Extracellular matrix receptors and the differentiation of human megakaryocytes in vitro

Leukemia and Lymphoma

Volumn 33, Issue 1-2, 1999, Pages 15-23

  Molla, Annie ^a   Mossuz, Pascal ^b,c   Berthier, Rolande ^c  

^a INSTITUT ALBERT BONNIOT   (France)

^b GRENOBLE UNIVERSITY HOSPITAL   (France)

^c CEA GRENOBLE   (France)

Author keywords

Extracellular matrix; Integrins; Megakaryocytic differentiation

Indexed keywords

BETA1 INTEGRIN; COLLAGEN; FIBRONECTIN; INTEGRIN; LAMININ; VERY LATE ACTIVATION ANTIGEN 2; VERY LATE ACTIVATION ANTIGEN 5;

ARTICLE; CELL ADHESION; CELL DIFFERENTIATION; CELL MATURATION; EXTRACELLULAR MATRIX; HUMAN; MEGAKARYOCYTE; PRIORITY JOURNAL; THROMBOCYTOPOIESIS;

EID: 0033014129     PISSN: 10428194     EISSN: None     Source Type: Journal    
DOI: 10.3109/10428199909093721     Document Type: Article

References (46)

1. Duperray, A., Berthier, R. and Marguerie, G. (1991). Biosynthesis and processing of platelets glycoproteins in megakaryocytes. In Blood Cell Biochemistry, Vol. 2, Megakaryocytes, Platelets, Macrophages and Eosinophils, edited by J.R. Harris, pp. 37-58. New York and London. Plenum Press.
2. Hynes, R.O. (1992). Integrins: versatility, modulation and signalling in cell adhesion. Cell. 69, 11-25.
3. Schwartz, M.A., Schaller, M.D. and Ginsberg, M. H. (1995). Integrins emerging paradigms of signal transduction. Annual Reviews in Cell and Developmental Biology. 11, 549-599.
4. Gewirtz, A. M. (1995). Megakaryocytopoiesis: the state of the art. Thrombosis and Haemostasis, 74, 204-209.
5. Avraham, H., Cowley, S., Chi, S.Y., Jiang, S. and Groopman, J. E. (1993). Characterization of adhesive interactions between human endothelial cells and megakaryocytes. Journal of Clinical Investigation. 91, 2378-2384.
6. Nagahisa, H., Nagata, Y., Ohnuki, T., Osada, M., Nagasawa, T., Abe, T. and Todokora, K. (1996). Bone marrow stromal cells produce thrombopoietin and stimulate megakaryocyte growth and maturation but suppress proplatelet formation Blood, 87, 1309-1316.
7. Kaushansky, K. (1995). Thrombopoietin: the primary regulator of platelet production. Blood, 86, 419-431.
8. Clark, B.R., Gallagher, J. T. and Dexter, T. M. (1992). Cell adhesion in the stromal regulation of haemopoiesis. Baillière's Clinical Haematology, 5, 619-651.
9. Verfaillie, C. M., Hurley, R., Bhatia, R and McCarthy, J. B. (1994). Role of bone marrow matrix in normal and abnormal hematopoiesis. Critical Review in Oncology and Hematology, 16, 201-224.
10. Vuillet-Gaugler, M.H., Breton-Gorius, J., Vainchenker, W., Guichard, J., Leroy, C., Tchernia, G. and Coulombel, L. (1990). Loss of attachment to fibronectin with terminal human erythroid differentiation. Blood, 75, 865-873.
11. Papayannopoulou, T. and Brice, M. (1992). Integrin expression profiles during erythroid differentiation. Blood, 79, 1686-1694.
12. Rosemblatt, M., Vuillet-Gaugler, M. H., Leroy, C. and Coulombel, L. (1991). Coexpression of two fibronectin receptors. VLA-4 and VLA-5, by immature human erythroblastic pre-cursor cells. Journal of Clinical Investigation, 87, 6-11.
13. Tsai, S., Patel, V., Beaumont, E., Lodish, H.F., Nathan, D.G. and Sieff, C. A. (1987) Differential binding of erythroid and myeloid progenitors to fibroblasts and fibronectin. Blood, 69, 1587-1594.
14. Verfaillie, CM., McCarthy, J.B. and McGlave, P.B. (1991). Differentiation of primitive human multipotent hematopoietic progenitors into single lineage clonogenic progenitors is accompanied by alterations in their interaction with fibronectin. Journal of Experimental Medicine, 174, 693-703.
15. Koenigsmann, M., Griffin, J.D., DiCarlo, J. and Cannistra, S.A. (1992). Myeloid and erythroid progenitor cells from normal bone marrow adhere to collagen type I. Blood, 79, 657-665.
16. Kerst, J.M., Sanders, J.B., Slaper-Cortenbach, I.C.M., Doorakkers, M.C., Hooibrink, B., van Oers, R.H.J., von der Borne, A.E.G.Kr. and van der School, C.E. (1993). α4β1 and α5β1 are differentially expressed during myelopoiesis and mediate the adherence of human CD34+ cells to fibronectin in an activation-dependent way. Blood, 81, 344-351.
17. Mossuz, P., Schweitzer, A., Molla, A. and Berthier, R. (1997). Expression and function of receptors for extracellular matrix molecules in the differentiation of human megakaryocytes in vitro. British Journal of Haematology, 98, 819-827.
18. Oostendorp, R. A. J. and Dörmer, P. (1997). VLA-4-mediated interactions between normal human hemalopoietic progenitors and stromal cells. Leukemia and Lymphoma, 24, 423-435.
19. Debili, N., Wendling, F., Katz, A., Guichard, J., Breton-Gorius, J., Hunt, P. and Vainchenker, W. (1995). The Mpl-ligand or thrombopoietin or megakaryocyte growth and differentiative factor has both direct proliferative and differentiative activities on human megakaryocyte progenitors. Blood, 86, 2516-2525.
20. Dolzhanskiy, A., Basch, R. S. and Karpatkin, S. (1997). The development of human megakaryocytes: III. Development of mature megakaryocytes from highly purified committed progenitors in synthetic culture media and inhibition of thrombopoietin-induced polyploidization by interleukin-3. Blood, 89, 426-434.
21. Kato, T., Horie, K., Hagiwara, T., Maeda, E., Tsumura, H., Ohashi, H. and Miyazaki, H. (1996). GpIIb/IIIa subpopulation of rat megakaryocyte progenitor cells exhibits high responsiveness to human thrombopoietin. Experimental Hematology, 24, 1209-1214.
22. Papayannopoulou, T., Brice, M., Farrer, D. and Kaushansky, K. (1996) Insights into the cellular mechanisms of erythropoietin-thrombopoietin synergy. Experimental Hematology, 24, 660-669.
23. Higuchi, T., Koike, K., Sawai, N. and Koike, T. (1997). Proliferative and differentiative potential of thrombopoietin-responsive precursors: expression of megakaryocytic and erythroid lineages. Experimental Hematology, 25, 463-470.
24. Tronik-Le Roux, D., Roullot, V., Schweitzer, A., Berthier, R. and Marguerie, G. (1995). Suppression of erythro-megakaryocytopoiesis and the induction of reversible thrombocytopenia in mice transgenic for the thymidine kinase gene targeted by the platelet αxIIb promoter. Journal of Experimental Medicine, 181, 2141-2153.
25. Tropel, P., Roullot, V., Vernet, M., Poujol, C., Pointu, H., Nurden, P., Marguerie, G. and Tronik-Le Roux, D. (1997). A 2.7-kb portion of the 5′ flanking region of the murine glycoprotein αIIb gene is transcriptionally active in primitive hematopoietic progenitor cells. Blood, 90, 2995-3004.
26. Lerat, H., Lissitzky, J. C., Singer, J.W., Keating, A., Herve, P. and Charbord, P. (1993). Role of stromal cells and macrophages in fibronectin biosynthesis and matrix assembly in human long-term marrow cultures. Blood, 82, 1480-1492.
27. Hemler, M. E. (1990). VLA proteins in the integrin family: Structures, functions, and their role on leukocytes. Annual Review of Immunology, 8, 365-400.
28. Guan, J. L. and Hynes, R.O. (1990). Lymphoid cells recognize an alternative spliced segment of fibronectin via the integrin receptor α4β1. Cell, 60, 53-61.
29. Pierschbacher, M. D. and Ruoslathi, E. (1984). The cell attachment activity of fibronectin can be duplicated by small synthetic fragments of the molecule. Nature, 309, 30-34.
30. Hagiwara, T., Nagasawa, T., Nagahisa, H., Takizawa, M., Osada, M., and Abe, T. (1996) Expression of adhesion molecules on cytoplasmic processes of human megakaryocytes. Experimental Hematoloxy, 24, 690-695.
31. Soligo, D., Schiro, R., Luksch, R., Manara, G., Quirici, N., Parravicini, C. and Lambertenghi Deliliers, E. (1990). Expression of integrins in human bone marrow. British Journal of Haematology, 76, 323-332.
32. Shattil, S. J. (1995) Function and regulation of the β3 integrins in hemostasis and vascular biology. Thrombosis and Haemostasis. 74, 149-155.
33. Tablin, F., Castro, M. and Leven, R. M. (1990); Blood platelet formation in vitro: The effects of extracellular matrix and cytoskeleton on megakaryocyte fragmentation. Journal of Cell Science, 97, 59-70.
34. Shattil, S. J., Ginsberg, M., H. and Brugge J. S. (1994) Adhesive signaling in platelets. Current Opinion in Cell Biology, 6, 695-704.
35. Brooks, P. C., Clark, R. A. F. and Cheresh, D. A. (1994) Requirement of vascular integrin αvβ3 for angiogenesis. Science, 264, 569-571.
36. Leven, R. M. and Tablin, F. (1992). Extracellular matrix stimulation of guinea pig megakaryocyte proplatelet formation in vitro is mediated through the vitronectin receptor. Experimental Hematology, 20, 1316-1322.
37. Handagama, P. , Scarborough, Shuman, M. A. and Bainton, D. F. (1993) Endocytosis of fibrinogen into megakaryocyte and platelet alpha-granules is mediated by αIIbβ3. Blood, 82, 135-138.
38. Zauli, G., Vitale, M., Falcieri, E., Gibellini, D., Bassini, A., Celeghini, C., Columharo, M. and Capitani, S. (1997). In vitro senescence and apoptotic cell death of human megakaryocytes. Blood, 90, 2234-2243.
39. Leven, R. (1995) Differential regulation of integrin-mediated proplatelet formation and megakaryocyte spreading. Journal of Cell Physiology 163, 597-607.
40. Levesque, J.P., Haylock, D. N. and Simmons P.J: (1996) Cytokine regulation of proliferation and cell adhesion are correlated events in human CD34+ hematopoietic progenitors. Blood, 88, 1168-1176.
41. Dedhar, S. and Hannigan, G.E. (1996). Integrin cytoplasmic interactions and bidirectional transmembrane signalling. Current Opinion in Cell Biology, 8, 657-669.
42. Cui, L., Ramstj̈ell, V., Borge, O.J;, Veiby, O.P., Lok, S. and Jacobsen, S. E. (1997) Thrombopoietin promotes adhesion of primitive human hemopoietic cells to fibronectin and vascular cell adhesion molecule-1: role of activation of very late antigen (VLA)-4 and VLA-5. Journal of Immunology, 159, 1961-1969.
43. Zauli, G., Bassini, A., Vitale, M., Gibellini, D., Celeghini, C., Caramelli, E., Pierpaoli, S;, Guidotti, L. and Capitani, S. (1997) Thrombopoietin enhances the αIIbβ3-dependent adhesion of megakaryocytic cells to fibrinogen or fibronectin through PI 3 kinase. Blood, 89, 883-895.
44. Choi, E. (1997) Regulation of proplatelet and platelet formation in vitro. In Thrombosis and Thrombopoietin: molecular, cellular, preclinical and clinical biology; Humana Press Inc. Totowa, NJ. 271-284.
45. Guerriero, R., Testa, H., Gabbianelli, M., Mattia, G., Montesoro, E., Macioce, G., Pace, A., Ziegler, B., Hassan, H.J. and Peschle, C. (1995). Unilineage megakaryocytic proliferation and differentiation of purified hematopoietic progenitors in serum-free liquid culture. Blood, 86, 3725-3736.
46. Choi, E. S., Nichol, J. L., Hokom, M. M., Hornkohl, A. C. and Hunt. P. (1995). Platelets generated in vitro from proplatelet-displaying human megakaryocytes are functional. Blood, 85, 402-413.