Hypermethylation of the Myf-3 gene in colorectal cancers: Associations with pathological features and with microsatellite instability

International Journal of Cancer

Volumn 84, Issue 2, 1999, Pages 109-113

  Shannon, Beverley ^a   Kay, Peter ^a   House, Anthony ^a   Iacopetta, Barry ^a  

^a UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

MICROSATELLITE DNA;

AGE; ARTICLE; CANCER INVASION; CANCER LOCALIZATION; CANCER STAGING; CANCER SURVIVAL; COLON CARCINOGENESIS; COLORECTAL CARCINOMA; CONTROLLED STUDY; DIAGNOSTIC VALUE; DISEASE ASSOCIATION; DNA DETERMINATION; DNA METHYLATION; GENETIC ASSOCIATION; HUMAN; HUMAN TISSUE; MICROSATELLITE INSTABILITY; PRIORITY JOURNAL; PROGNOSIS;

ADENOMA; AGE FACTORS; CARCINOMA; COLORECTAL NEOPLASMS; DNA METHYLATION; DOSAGE COMPENSATION, GENETIC; HUMANS; INTESTINAL MUCOSA; MICROSATELLITE REPEATS; MIDDLE AGED; MYOD PROTEIN;

EID: 0033007587     PISSN: 00207136     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0215(19990420)84:2<109::AID-IJC3>3.0.CO;2-F     Document Type: Article

References (25)

1. AHUJA, N., AVINASH, L., MOHAN, Q., STOLKER, J., HERMAN, J., HAMILTON, S., BAYLIN, S. and ISSA, J., Association between CpG island methylation and microsatellite instability in colorectal cancer. Cancer Res., 57, 3370-3374 (1997).
2. BAYLIN, S., HERMAN, J., GRAFF, J., VERTINO, P. and ISSA, J., Alterations in DNA methylation: a fundamental aspect of neoplasia. Adv. Cancer Res., 72, 141-196 (1998).
3. BAYLIN, S., MAKOS, M., WU, J., YEN, R., DEBUSTROS, A., VERTINO, P. and NELKIN, B., Abnormal patterns of DNA methylation in human neoplasia: potential consequences for tumour progression. Cancer Cells, 3, 383-390 (1991).
4. BRANDEIS, M., ARIEL, M. and CEDAR, H., Dynamics of DNA methylation during development. Bioessays, 15, 709-713 (1993).
5. BRAUN, T., BOBER, E., BUSCHHAUSEN-DENKER, G., KOTZ, S., GRZESCHIK, K.-H. and ARNOLD, H., Differential expression of myogenic determination genes in muscle cells: possible autoactivation by the Myf gene products. EMBO J., 8, 3617-3625 (1989).
6. CHENG, P., SCHMUTTE, C., COFER, C., FELIS, J., YU, M. and DUBEAU, L., Alterations in DNA methylation are early, but not initial, events in ovarian tumorigenesis. Brit. J. Cancer, 75, 396-402 (1997).
7. CRESCENZI, M., FLEMING, K., LASSAR, A., WEINTRAUB, H. and AARONSON, S., MyoD induces growth arrest independent of differentiation in normal and transformed cells. Proc. nat. Acad. Sci. (Wash.), 87, 8442-8446 (1990).
8. DE BUSTROS, A., NELKIN, B., SILVERMAN, A., EHRLICH, G., POIESZ, B. and BAYLIN, S., The short arm of chromosome 11 is a "hot spot" for hypermethylation in human neoplasia. Proc. nat. Acad. Sci. (Wash.), 85, 5693-5697 (1988).
9. DIX, B., ROBBINS, P., SPAGNOLO, D., PADOVAN, G., HOUSE, A. and IACOPETTA, B., Clonal analysis of colorectal tumours using K-ras and p53 gene mutations as markers. Diagn. mol. Pathol., 4, 261-265 (1995).
10. DUTRILLAUX, B., Pathways of chromosome alteration in human epithelial cancers. Adv. Cancer Res., 67, 59-82 (1995).
11. HAHNEL, R., HARVEY, J. and KAY, P., Hypermethylation of the myogenic gene Myf-3 in human breast carcinomas. Anticancer Res., 16, 2111-2115 (1996).
12. HILTUNEN, M., ALHONEN, L., KOISTINAHO, J., MYOHANEN, S., MARIN, S., KOSMA, V. PAAKONEN, M. and JANNE, J., Hypermethylation of the WT1 and calcitonin gene promoter regions at chromosome 11p in human colorectal cancer. Int. J. Cancer, 70, 644-648 (1997).
13. IACOPETTA, B., HARMAN, D., SPAGNOLO, D., HOUSE, A. and KAY, P., Hypermethylation of the Myf-3 gene in human colorectal cancer. Anticancer Res., 17, 429-432 (1997).
14. IACOPETTA, B., WELCH, J., SOONG, R., HOUSE, A., ZHOU, X. and HAMELIN, R., Mutation of the transforming growth factor-β type II receptor gene in right-sided colorectal cancer: relationship to clinicopathological features and genetic alterations. J. Pathol., 184, 390-395 (1998).
15. ISSA, J., VERTINO, P., BOEHM, C., NEWSHAM, I. and BAYLIN, S., Switch from monoallelic to biallelic human IGF2 promoter methylation during aging and carcinogenesis. Proc. nat. Acad. Sci. (Wash.), 93, 11757-11762 (1996).
16. KANE, M., LODA, M., GAIDA, G., LIPMAN, J., MISHRA, R., GOLDMAN, H., JESSOP, J. and KOLODNER, M., Methylation of the hMLH1 promoter correlates with lack of expression of hMLH1 in sporadic colon tumours and mismatch repair-defective human tumour cell lines. Cancer Res., 57, 808-811 (1997).
17. KAY, P., TAYLOR, J., KEES, U., BAKER, D. and SPAGNOLO, D., Myf-3 hypermethylation in malignant lymphoproliferative disorders. Int. J. Cancer, 62, 797-799 (1995).
18. LENGAUER, C., KINZLER, K. and VOGELSTEIN, B., Genetic instability in colorectal cancers. Nature, 386, 623-627 (1997a).
19. LENGAUER, C., KINZLER, K. and VOGELSTEIN, B., DNA methylation and genetic instability in colorectal cancer cells. Proc. nat. Acad. Sci. (Wash.), 94, 2545-2550 (1997b).
20. MENKO, F., Genetics of colorectal cancer for clinical practice, pp. 31-112, Kluwer, Dordrecht (1993).
21. RIDEOUT, W., EVERSOLE-CIRE, P., SPRUCK, C., HUSTAD, C., COETZEE, G., GONZALES, F. and JONES, P., Progressive increases in the methylation status and heterochromatization of the MvoD CpG island during oncogenic transformation. Mol. Cell Biol., 14, 6143-6152 (1994).
22. STIRZAKER, C., MILLAR, D., PAUL, C., WARNECKE, P., HARRISON, J., VINCENT, P., FROMMER, M. and CLARK, S., Extensive DNA methylation spanning the Rb promoter in retinoblastoma tumours. Cancer Res., 57, 2229-2237 (1997).
23. TAJBAKHSH, S., ROCANCOURT, D., COSSU, G. and BUCKINGHAM, M., Redefining the genetic hierarchies controlling skeletal myogenesis: Pax-3 and Myf-5 act upstream of MyoD. Cell, 89, 127-138 (1997).
24. TYCKO, B., DNA methylation in genomic imprinting. Mutation Res., 386, 131-140 (1997).
25. ZHOU, X.-P. and 14 OTHERS, Determination of the replication error phenotype in human tumours without the requirement for matching normal DNA by analysis of mononucleotide repeat microsatellites. Genes Chromosomes Cancer, 21, 101-107 (1997).