Extracellular ATP: A further modulator in neuroendocrine control of the thymus

NeuroImmunoModulation

Volumn 6, Issue 1-2, 1999, Pages 81-89

  Alves, Luiz A ^a   Coutinho Silva, Robson ^b   Savino, Wilson ^a  

^a INSTITUTO OSWALDO CRUZ   (Brazil)

^b FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

Author keywords

ATP; Purinergic receptors; Thymic epithelial cells; Thymic nurse cells

Indexed keywords

ADENOSINE TRIPHOSPHATE; PURINE RECEPTOR;

ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CELL MATURATION; DENDRITIC CELL; EXTRACELLULAR MATRIX; MAJOR HISTOCOMPATIBILITY COMPLEX; NEUROENDOCRINE SYSTEM; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SECOND MESSENGER; STEM CELL; T LYMPHOCYTE ACTIVATION; THYMUS;

ADENOSINE TRIPHOSPHATE; ANIMALS; APOPTOSIS; CALCIUM; HUMANS; LYMPHOCYTES; MODELS, BIOLOGICAL; RECEPTORS, PURINERGIC P2; SIGNAL TRANSDUCTION; THYMUS GLAND;

EID: 0033006926     PISSN: 10217401     EISSN: None     Source Type: Journal    
DOI: 10.1159/000026367     Document Type: Article

References (90)

1. Robey EA, Fowlkes B: Selective events in T cell development. Annu Rev Immunol 1994;12: 675-705.
2. Dardenne M, Savino W: Control of thymus physiology by peptide hormones and neuropeptides. Immunol Today 1994;15:518-523.
3. van Ewijk W: T-cell differentiation is influenced by thymic microenvironments. Annu Rev Immunol 1991;9:591-615.
4. Boyd RL, Tucek CL, Godfrey DI, Izon DJ, Wilson TJ, Davidson NJ, Bean AGD, Ladyman HM, Ritter MA, Hugo P: The thymic microenvironment. Immunol Today 1993; 14: 445-459.
5. Coutinho-Silva R, Alves LA, Campos-de-Carvalho AC, Savino W, Persechini PM: Characterization of P2Z purinergic receptors on phagocytic cells of the thymic reticulum in culture. Biochim Biophys Acta 1996;1280:217-222.
6. Coutinho-Silva R, Alves LA, Savino W, Persechini PM: A cation non-selective channel induced by extracellular ATP in macrophages and phagocytic cells of thymic reticulum. Biochim Biophys Acta 1996;1278:125-130.
7. Apasov S, Koshiba M, Redegeld F, Sitkovsky MV: Role of extracellular ATP and P1 and P2 classes of purinergic receptors in T-cell development and cytotoxic T lymphocyte effector functions. Immunol Rev 1995;146:5-19.
8. Dubyak GR, EI-Moatassim C: Signal transduction via P2-purinergic receptors for extracellular ATP and other nucleotides. Am J Physiol 1993;265:C577-C606.
9. Brake AJ, Julius D: Signaling by extracellular nucleotides. Annu Rev Cell Dev Biol 1996;12: 19-541.
10. Carr WES, Gleeson RA, Ache BW, Milstead ML: Olfactory receptors of the spiny lobster: ATP-sensitive cells similarities to P2-type purinoreceptors of vertebrates. J Comp Physiol A 1986;158:331-338.
11. Devreotes PN, Zigmond SH: Chemotaxis in eukaryotic cells: A focus on leukocytes and Dictyostelitim. Annu Rev Cell Biol 1988;4:649-686.
12. Olah ME, Stiles GL: Adenosine receptor sub-types: Characterization and therapeutic regulation. Annu Rev Pharmacol Toxicol 1995;35: 581-597.
13. Fredholm BB, et al: Sixth Nomenclature and Classification of Purinoceptors. Pharmacol Rev 1994;46:143-156.
14. Chen ZP, Levy A, Lightman SL: Nucleotides as extracellular signalling molecules. J Neuroendocrinol 1995;7:83-96.
15. Bertrand G, Chapal J, Loubatieres-Mariani MM: Potentiating synergism between adenosine diphosphate or triphosphate and acetylcholine on insulin secretion. Am J Physiol 1986;251:E416-E421.
16. Liu P, Wen M, Hayashi J: Characterization of ATP receptor responsible for the activation of phospholipase A2 and stimulation of prostaglandin E2 production in thymic epithelial cells. Biochem J 1995;308:399-404.
17. El-Moatassim C, Dornand J, Mani JC: Extracellular ATP increases cytosolic free calcium in thymocytes and initiates the blastogenesis of the phorbol 12-myristate 13-acetate-treated medullary population. Biochim Biophys Acta 1987;927:437-444.
18. Baricordi OR, Ferrari D, Melchiorri L, Chiozzi P, Hanau S, Chiari E, Rubini M, DiVirgilio F: An ATP-activated channel is involved in mitogenic stimulation of human T lymphocytes. Blood 1996;87:682-690.
19. Jamieson GP, Snook MB, Thurlow PJ, Wiley JS: Extracellular ATP causes loss of L-selectin from human lymphocytes via occupancy of P2Z purinoceptors. J Cell Physiol 1996;166: 637-642.
20. 4- permeabilizes thymocytes not only to cations but also to low-molecular-weight solutes. Eur J Pharmacol 1990;181: 111-118.
21. DiVirgilio F, Bronte V, Collavo D, Zanovello P: Responses of mouse lymphocytes to extracellular adenosine 5′-triphosphate (ATP): Lymphocytes with cytotoxic activity are resistant to the permeabilizing effects of ATP. J Immunol 1989;143:1955-1960.
22. Pizzo P, Zanovello P, Bronte V, DiVirgilio F: Extracellular ATP causes lysis of mouse thymocytes and activates a plasma membrane ion channel. Biochem J 1991;274:139-144.
23. Persechini PM, Bisaggio RC, Alves-Neto JL, Coutinho-Silva R: Extracellular ATP in the lymphohematopoietic system: P2Z purinoceptors and membrane permeabilization. Braz J Med Biol Res 1998;31:25-34.
24. Wiley JS, Mayger W, Cragoe EJ, Jopson M: Extracellular ATP opens an amiloride-sensitive cation channel in human lymphocytes. Ann NY Acad Sci 1990;603:439-440.
25. + uptake: Inhibition of fluxes by suramin. Arch Biochem Biophys 1993;305:54-60.
26. Bretschneider F, Klapperstuck M, Lohn M, Markwardt F: Nonselective cationic currents elicited by extracellular ATP in human and Blymphocytes. Eur J Physiol 1995;429:691-698.
27. Albuquerque C, Oliveira SM, Coutinho-Silva R, Oliveira-Castro GM, Persechini PM: ATP-and UTP-induced currents in macrophages and macrophage-polykaryons. Am J Physiol 1993;265:C1663-C1673.
28. Markwardt F, Lohn M, Bohm T, Klapperstuck M: Purinoceptor-operated cationic channels in human b lymphocytes. J Physiol 1997;498: 143-151.
29. Valeva A, Weisser A, Walker B, Kehoe M, Bayley H, Bhakdi S, Palmer M: Molecular architecture of a toxin pore - a 15-residue sequence lines the transmembrane channel of staphylococcal alpha-toxin. EMBO J 1996;15:1857-1864.
30. Blanchard DK, Hoffman SL, Djeu JY: Inhibition of extracellular ATP-mediated lysis of human macrophages by calmodulin antagonists. J Cell Biochem 1995;57:452-464.
31. Nuttle LC, Dubyak GR: Differential activation of cation channels and non-selective pores by macrophage P-2Z purinergic receptors expressed in Xenopus oocytes. J Biol Chem 1994; 269:13988-13996.
32. 7 purinoceptor expression in Xenopus oocytes is not sufficient to produce a pore-forming P2Z-like phenotype. FEBS Lett 1997;411:339-345.
33. Coutinho-Silva R, Persechini PM: P2Z purinoceptor-associated pores induced by extracellular ATP in macrophages and J774 cells. Am J Physiol 1997;273:C1793-C1800.
34. Nagy P, Panyi G, Jenei A, Bene L, Caspar R, Matko J, Damjanovich S: Ion-channel activities regulate transmembrane signaling in thymocyte apoptosis and T-cell activation. Immunol Lett 1995;44:91-95.
35. Chused TM, Apasov S, Sitkovsky M: Murine T lymphocytes modulate activity of an ATP-activated P-2z-type purinoceptor during differentiation. J Immunol 1996;157:1371-1380.
36. Ross PE, Ehring GR, Cahalan MD: Dynamics of ATP-induced calcium signaling in single mouse thymocytes. J Cell Biol 1997; 138:987-998.
37. 1 in thymocyte apoptosis. Immunity 1996;5:275-283.
38. Koshiba M, Apasov S, Sverdlov V, Chen P, Erb L, Turner JT, Weisman GA, Sitkovsky MV: Transient up-regulation of P2Y2 nucleotide receptor mRNA expression is an immediate early gene response in activated thymocytes. Proc Natl Acad Sci USA 1997;94:831-836.
39. Jiang S, Kull B, Fredholm BB, Orrenius S: P2X purinoceptor is not important in thymocyte apoptosis. Immunol Lett 1996;49:197-201.
40. Huang S, Apasov S, Koshiba M, Sitkovsky M: Role of A2a extracellular adenosine receptor-mediated signaling in adenosine-mediated inhibition of T-cell activation and expansion. Blood 1997;90:1600-1610.
41. Eichmann KA: Signal strength hypothesis of thymic selection: Preliminary considerations. Immunol Lett 1995;44:87-90.
42. Wang CR, Hashimoto K, Kubo S, Yokochi T, Kubo M, Suzuki M, Suzuki K, Tada T, Nakayama T: T-Cell receptor-mediated signaling events in CD4+CD8+ thymocytes undergoing thymic selection: Requirement of calcineurin activation of thymic positive selection but not negative selection. J Exp Med 1995;181:927-941.
43. Guidos JC: Positive selection of CD4+ and CD8 cells. Curr Opin Immunol 1996;8:225-232.
44. Andjelic S, Jain N, Nikolic-Zugic J: Immature thymocytes become sensitive to calcium-mediated apoptosis with the onset of CD8, CD4, and the T cell receptor expression: A role for bcl-2? J Exp Med 1993;178:1745-1751.
45. Zheng LM, Zychlinsky A, Liu CC, Ojcius DM, Young JDE: Extracellular ATP as a trigger for apoptosis or programmed cell death. J Cell Biol 1991;112:279-288.
46. Gargett CE, Cornish EJ, Wiley JS: Phospholipase D activation by P-2Z-purinoceptor agonists in human lymphocytes is dependent on bivalent cation influx. Biochem J 1996;313: 529-535.
47. Bronte V, Macino B, Zambon A, Rosato A, Mandruzzato S, Zanovello P, Collavo D: Protein tyrosine kinases and phosphatases control apoptosis induced by extracellular adenosine 5′-triphosphate. Biochem Biophys Res Commun 1996;218:344-351.
48. Hogquist KA, Nett MA, Unanue ER, Chaplin DD: Interleukin-1 is processed and released during apoptosis. Proc Natl Acad Sci USA 1991;88:8485-8489.
49. Perregaux D, Gabel CA: Interleukin-1β maturation and release in response to ATP and nigericin. J Biol Chem 1994;269:15195-15203.
50. Cohen GM: Caspases: the executioners of apoptosis. Biochem J 1997;326:1-16.
51. Gordon JL: Extracellular ATP: Effects, sources and fate. Biochem J 1986;233:309-319.
52. Abraham EH, Prat AG, Gerweck L, Seneveratne T, Arceci RJ, Kramer R, Guidotti G, Cantiello HF: The multidrug resistance (mdrl) gene product functions as an ATP channel. Proc Natl Acad Sci USA 1993;90:312-316.
53. Reisin IL, Prat AG, Abraham EH, Amara JF, Gregory RJ, Ausiello DA, Cantiello HF: The cystic fibrosis transmembrane conductance regulator is a dual ATP and chloride channel. J Biol Chem 1994;269:20584-20591.
54. Schwiebert EM, Egan M, Hwang TH, Fulmer SB, Allen S, Cutting GR, Guggino WB: CFTR regulates outwardly rectifying chloride channels through an autocrine mechanism involving ATP. Cell 1995;81:1063-1073.
55. Ferrari D, Chiozzi P, Falzoni S, Hanau S, DiVirgilio F: Purinergic modulation of interleukin-1-beta release from microglial cells stimulated with bacterial endotoxin. J Exp Med 1997;185:579-582.
56. Blanchard DK, Wei S, Duan CN, Pericle F, Diaz JI, Djeu JY: Role of extracellular adenosine triphosphate in the cytotoxic T-lymphocyte-mediated lysis of antigen presenting cells. Blood 1995;85:3173-3182.
57. 1 receptor activation in HL60 cells. Blood 1996;87:2659-2664.
58. Filippini A, Taffs RE, Sitkovsky MV: Extracellular ATP in T-lymphocyte activation: Possible role in effector functions. Proc Natl Acad Sci USA 1990;87:8267-8271.
59. Feiten SY, Feiten DL, Bellinger DL, Carlson SL, Ackerman KD, Madden KS, Olschowka JA, Livnat S: Noradrenergic sympathetic innervation of lymphoid organs. Prog Allergy 1988;43:14-36.
60. Kugelgen I, Klaus S: Noradrenaline-ATP co-transmission in the sympathetic nervous system. Trends Pharmacol Sci 1991;12:319-324.
61. Bulloch K, Moore RY: Innervation of the thymus gland by brain stem and spinal cord in the mouse and rat. Am J Anat 1984;162:157-166.
62. Marchetti B, Morale MC, Paradis P, Bouvier M: Characterization, expression, and hormonal control of a thymic beta-2-adrenergic receptor. Am J Physiol 1994;267:E718-E731.
63. Kurz B, Feindt J, von Gaudecker B, Kranz A, Loppnow H, Mentlein R: Beta-adrenoceptor-mediated effects in rat cultured thymic epithelial cells. Br J Pharmacol 1997;120:1401-1408.
64. Singh U, Fatani JA, Mohajir AM: Ontogeny of cholinergic innervation of thymus in mouse. Dev Comp Immunol 1987;11:627-635.
65. Lammas DA, Stober C, Harvey CJ, Kendrick N, Panchalingam S, Kumararatne DS: ATP-induced killing of mycobacteria by human macrophages is mediated by purinergic P2Z(P2X7) receptors. Immunity 1997;7:433-444.
66. Fredholm BB: Purines and neutrophil leukocytes. Gen Pharmacol 1997;28:345-350.
67. Valera S, Hussy N, Evans RJ, Adami N, North RA, Surprenant A, Buell G: A new class of ligand-gated ion channel defined by P2X receptor for extracellular ATP. Nature 1994;317: 516-519
68. Brake AJ, Wagenbach MJ, Julius D: New structural motif for ligand-gated ion channels defined by an ionotropic ATP receptor. Nature 1994;317:519-523.
69. Lewis C, Neidhart S, Holy C, North RA, Buell G, Surprenant A: Coexpression of P2X2 and P2X3 receptor subunits can account for ATP-gated currents in sensory neurons. Nature 1995;377:432-435.
70. Chen CC, Akoplan AN, Sivilloti L, Colquhoun D, Burnstock G, Wood JN: A P2X purinoceptor expressed by a subset of sensory neurons. Nature 1995;377:428-431.
71. Wang CZ, Namba N, Gonoi T, Inagaki N, Seino S: Cloning and pharmacological characterization of a fourth P2X receptor subtype widely expressed in brain and peripheral tissues including various endocrine tissues. Biochem Biophys Res Commun 1996;220:196-202.
72. Soto F, Garcia-Guzman M, Gomez-Hernandez JM, Hollmann M, Karschin C, Stuhmer W: P2X4: An ATP-activated ionotropic receptor cloned from rat brain. Proc Natl Acad Sci USA 1996;93:3684-3688.
73. Buell G, Lewis C, Collo G, North RA, Suprenant A: An antagonist-insensitive P2X receptor expressed in epithelia and brain. EMBO J 1996;15:55-62.
74. Bo X, Zhang Y, Nassar M, Burnstock G, Shoepfer R: A P2X purinoceptor cDNA conferring a novel pharmacological profile. FEBS Lett 1995:375:129-133.
75. Garcia-Guzman M, Soto F, Laube B, Stuhmer W: Molecular cloning and functional expression of a novel rat heart P2X purinoceptor. FEBS Lett 1996;388:123-127.
76. Soto F, Garcia-Guzman M, Karschin C, Stuhmer W: Cloning and tissue distribution of a novel P2X receptor from rat brain. Biochem Biophys Res Commun 1996;223:456-460.
77. Suprenant A, Rassendren F, Kawashima E, North RA, Buell G: The cytolytic P2Z receptor for extracellular ATP identified as a P2X receptor (P2X7). Science 1996;272:735-738.
78. 7. J Biol Chem 1997;272: 5482-5486.
79. Tokuyama Y, Hara M, Jones EMC, Fan Z, Bell I: Cloning of rat and mouse P2Y purinoreceptors. Biochem Biophys Res Commun 1995; 211:211-218.
80. Parr CE, Sullivan DM, Paradiso AM, Lazorowski ER, Burch LH, Olsen JC, Erb L, Weisman GA, Boucher RC, Turner JT: Cloning and expression of a human P2U nucleotide receptor, a target for cystic fibrosis pharmacotherapy. Proc Natl Acad Sci USA 1994;91:3275-3279.
81. Lustig KD, Shiau AK, Brake AJ, Julius D: Expression cloning of an ATP receptor from mouse neuroblastoma cells. Proc Natl Acad Sci USA 1993;90:5113-5117.
82. Webb TE, Henderson D, King BF, Wang S, Simon J, Bateson AN, Bumstock G, Barnard EA: A novel G protein-coupled P2 purinoceptor (P2Y3) activated preferentially by nucleoside diphosphates. Mol Pharmacol 1996;50: 258-265.
83. Barnard EA, Burnstock G, Webb TEG: Protein-coupled receptors for ATP and other nucleotides: A new receptor family. Trends Pharmacol Sci 1994;15:67-70.
84. Nguyen T, Erb L, Weiman GA, Marchese A, Heng HHQ, Garrad RC, George SR, Turner JT, O'Dowd BF: Cloning, expression, and chromosomal localization of the human uridine nucleotide receptor gene. J Biol Chem 1995;270:30845-30848.
85. Communi D, Pirotton S, Parmentier M, Boeynaems JM: Cloning and functional expression of a human uridine nucleotide receptor. J Biol Chem 1995;270:30849-30852.
86. Webb TE, Kaplan MG, Barnard EA: Identification of 6H1 as a P2Y purinoreceptor: P2Y5. Biochem Biophys Res Commun 1996;219: 105-110.
87. Chang K, Hanaoka K, Kumada M, Takuwa Y: Molecular cloning and functional analysis of a novel P2 nucleotide receptor. J Biol Chem 1995;270:26152-26158.
88. Communi D, Pirotton S, Parmentier M, Boeynaems JM: Cloning, functional expression and tissue distribution of the human PY6 receptor. Biochem Biophys Res Commun 1996;222: 303-308.
89. Akbar GKM, Dasari VR, Webb TE, Ayyanathan K, Pillarisetti K, Sandhu AK, Athwal RS, Daniel JL, Ashby B, Banard EA, Kunapuli SP: Molecular cloning of a novel P2 purinoceptor from human erythroleukemia cells. J Biol Chem 1996;271:18363-18367.
90. Bogdanov YD, Dale L, King BF, Whittock N, Bumstock G: Early expression of a novel nucleotide receptor in neural plate of Xenopus embryos. J Biol Chem 1997;272:12583-12590.