3-Hydroxy-3-methylglutaryl CoA reductase inhibitors reduce serum triglyceride levels through modulation of apolipoprotein C-III and lipoprotein lipase

FEBS Letters

Volumn 452, Issue 3, 1999, Pages 160-164

  Schoonjans, Kristina ^a   Peinado Onsurbe, Julia ^b   Fruchart, Jean Charles ^a   Tailleux, Anne ^a   Fiévet, Catherine ^a   Auwerx, Johan ^a  

^a INSERM   (France)

^b UNIVERSITY OF BARCELONA   (Spain)

Author keywords

Atherosclerosis; Gene regulation; Hypolipidemic drug; Sterol response element binding protein 1 adipocyte determination and differentiation factor 1; Triglyceride

Indexed keywords

ANTILIPEMIC AGENT; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; LIPOPROTEIN LIPASE; LOW DENSITY LIPOPROTEIN RECEPTOR; SIMVASTATIN; STATINE DERIVATIVE; STEROL REGULATORY ELEMENT BINDING PROTEIN; VERY LOW DENSITY LIPOPROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ATHEROSCLEROSIS; CHOLESTEROL METABOLISM; CONTROLLED STUDY; DRUG MECHANISM; ENZYME ACTIVITY; LIPOLYSIS; MALE; NONHUMAN; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; RAT; TRIACYLGLYCEROL BLOOD LEVEL;

ANIMALS; APOLIPOPROTEIN A-I; APOLIPOPROTEIN A-II; APOLIPOPROTEIN C-III; APOLIPOPROTEINS C; CHOLESTEROL; CHOLESTEROL, HDL; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; LIPOPROTEIN LIPASE; MALE; RATS; RATS, SPRAGUE-DAWLEY; SIMVASTATIN; TRIGLYCERIDES;

EID: 0033006201     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-5793(99)00632-8     Document Type: Article

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