Differing roles of adenosine receptor subtypes in retinal ischemia- reperfusion injury in the rat

Experimental Eye Research

Volumn 68, Issue 1, 1999, Pages 9-17

  Li, Bing ^a   Rosenbaum, Pearl S ^c   Jennings, Nuala M ^b   Maxwell, Kelly M ^a   Roth, Steven ^a  

^a UNIVERSITY OF CHICAGO   (United States)

^b UNIVERSITY OF CHICAGO   (United States)

^c ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

Adenosine; CSC; DPCPX; Ischemia; Rat; Retina

Indexed keywords

8 CYCLOPENTYL 1,3 DIPROPYLXANTHINE; ADENOSINE RECEPTOR; RECEPTOR SUBTYPE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ELECTRORETINOGRAM; HISTOPATHOLOGY; MICROSCOPY; NONHUMAN; PRIORITY JOURNAL; RAT; REPERFUSION INJURY; RETINA ISCHEMIA;

EID: 0033004985     PISSN: 00144835     EISSN: None     Source Type: Journal    
DOI: 10.1006/exer.1998.0573     Document Type: Article

References (32)

1. Aden, U., Lindstrom, K., Bona, E., Hagberg, H. and Fredholm, B. B. (1994). Changes in adenosine receptors in the neonatal rat brain following hypoxic ischemia. Mol. Brain Res. 23, 354-8.
2. Bisserbe, J. C., Pascal, O., Deckert, J. and Maziere, B. (1992). Potential use of DPCPX as a probe for in vivo localization of brain A1 receptors. Brain Res. 599, 6-12.
3. Blazynski, C. (1990). Discrete distributions of adenosine receptors in mammalian retina. J. Neurochem. 54, 648-55.
4. Blazynski, C. and Perez, M. T. (1991). Adenosine in vertebrate retina: Localization, receptor characterization, and function. Cell. Mol. Neurobiol. 11, 463-84.
5. Braas, K.M., Zarbin, M. A. and Snyder, S. H. (1987). Endogenous adenosine and adenosine receptors localized to ganglion cells of the retina. Proc. Natl. Acad. Sci. USA 84, 3906-10.
6. Coates, J., Sheehan, M. J. and Strong, P. (1994). 1,3-Dipropyl-8-cyclopentyl xanthine (DPCPX): A useful tool for pharmacologists and physiologists. Gen. Pharmacol. 25, 387-94.
7. +-ATP channels mediate adenosine-induced hyperemia in retina. Invest. Ophthalmol. Vis. Sci. 37, 2624-33.
8. Gidday, J. M. and Park, T. S. (1993). Adenosine-mediated autoregulation of retinal arteriolar tone in the piglet. Invest. Ophthalmol. Vis. Sci. 34, 2713-19.
9. Hughes, W. F. (1991). Quantitation of ischemic damage in the rat retina. Exp. Eye Res. 53, 573-82.
10. Jacobson, K. A., Nikodijevic, O., Padgett, W. L., Gallo-Rodriquez, C., Maillard, M. and Daly, J. W. (1993). 8-(3-Chlorostyryl)caffeine (CSC) is a selective A2-adenosine antagonist in vitro and in vivo. FEBS Lett. 323, 141-4.
11. Kvanta, A., Seregard, S., Sejersen, S., Kull, B. and Fredholm, B. B. (1997). Localization of adenosine receptor messenger RNAs in the rat eye. Exp. Eye Res. 65, 595-602.
12. Larsen, A. K. and Osborne, N. N. (1996). Involvement of adenosine in retinal ischemia: Studies in the rat. Invest. Ophthalmol. Vis. Sci. 37, 2603-11.
13. Latini, S., Pazzagli, M., Pepe, G. and Pedata, F. (1996). A2 adenosine receptors: Their presence and neuromodulatory role in the central nervous system. Gen. Pharmacol. 27, 925-33.
14. Lee, K. S., Tetzlaff, W. and Kreutzberg, G. W. (1986). Rapid down regulation of hippocampal adenosine receptors following brief anoxia. Brain Res. 380, 155-8.
15. Nagasawa, H., Araki, T. and Kogure, K. (1994). Alteration of adenosine A1 receptor binding in the post-ischemic rat brain. NeuroReport 5, 1453-6.
16. Nehlig, A., Daval, J.-L. and Boyet, S. (1994). Effects of selective adenosine A1 and A2 receptor agonists and antagonists on local rates of energy metabolism in the rat brain. Eur. J. Pharmacol. 258, 57-66.
17. Ostwald, P., Goldstein, I. M., Pachnanda, A. and Roth, S. (1995). Effect of nitric oxide synthase inhibition on blood flow after retinal ischemia in cats. Invest. Ophthalmol. Vis. Sci. 36, 2396-403.
18. Ostwald, P., Park, S. S., Toledano, A. Y. and Roth, S. (1997). Adenosine receptor blockade and nitric oxide synthase inhibition: Impact upon blood flow and the electro-retinogram following retinal ischemia. Vision Res. 37, 3453-61.
19. Phillis, J. W. (1995). The effects of selective A1 and A2a adenosine receptor antagonists on cerebral ischemic injury in the gerbil. Brain Res. 705, 79-4.
20. Rosenbaum, D. M., Rosenbaum, P. S., Gupta, A., Michaelson, M. D., Hall, D. H. and Kessler, J. A. (1997). Retinal ischemia leads to apoptosis which is ameliorated by aurintricarboxylic acid. Vision Res. 37, 3443-51.
21. Rosenbaum, P. S., Roth, S. and Mosseri, M. (1992). Protective effects of cyclohexyladenosine during experimental retinal ischemia (abstract). Invest. Ophthalmol. Vis. Sci. 33, 1125.
22. Roth, S., Osinski, J., Park, S., Ostwald, P. and Moshfeghi, A. (1996). Measurement of purine nucleoside concentration in the intact rat retina. J. Neurosci. Methods 68, 87-90.
23. Roth, S., Park, S. S., Sikorski, C. W., Osinski, J., Chan, R. and Loomis, K. (1997a). Concentrations of adenosine and its metabolites in the rat retina/choroid during reperfusion after ischemia. Curr. Eye Res. 16, 875-85.
24. Roth, S., Rosenbaum, P. S., Park, S. S., Osinski, J., Toledano, A. Y. and Moshfeghi, A. A. (1997b). Ischemia induces significant changes in purine nucleoside concentration in the retina-choroid in rats. Exp. Eye Res. 65, 771-9.
25. Roth, S., Li, B., Rosenbaum, P. S., Gupta, H., Goldstein, I. M., Maxwell, K. M. and Gidday, J. M. (1998). Preconditioning provides complete protection against retinal ischemic injury in rats. Invest. Ophthalmol. Vis. Sci. 39, 777-85.
26. Rudolphi, K. A. and Schubert, P. (1997). Modulation of neuronal and glial cell function by adenosine and neuroprotection in vascular dementia. Behav. Brain Res. 83, 123-8.
27. Sebastiao, A. M. and Ribeiro, J. A. (1996). Adenosine A2 receptor-mediated excitatory actions on the nervous system [Review]. Prog. Neurobiol. 48, 167-89.
28. Sweeney, M. I. (1997). Neuroprotective effects of adenosine in cerebral ischemia: Window of opportunity. Neurosci. Behav. Rev. 21, 207-17.
29. Takagi, H., King, G. L., Robinson, G. S., Ferrara, N. and Aiello, L. P. (1996). Adenosine mediates hypoxic induction of vascular endothelial growth factor in retinal pericytes and endothelial cells. Invest. Ophthalmol. Vis. Sci. 37, 2165-76.
30. von Lubitz, D. K., Lin, R. C. S. and Jacobson, K. A. (1995a). Cerebral ischemia in gerbils: Effects of acute and chronic treatment with adenosine A2a receptor agonist and antagonist. Eur. J. Pharmacol. 287, 295-302.
31. von Lubitz, D. K., Carter, M. F., Beenhakker, M., Lin, R. C. and Jacobson, K. A. (1995b). Adenosine: A protherapeutic concept in neurodegeneration. In Neuroprotective Agents: Experimental and Clinical Perspectives (B. Trembly eds.). Pp. 160-78. NY Academy of Sciences: New York, U.S.A.
32. Zhu, Y. and Gidday, J. M. (1996). Hypoglycemic hyperemia in retina of newborn pigs. Involvement of adenosine. Invest. Ophthalmol. Vis. Sci. 37, 86-92.