Cell kinetics and repopulation parameters of irradiated xenograft tumours in SCID mice: Comparison of two dose-fractionation regimens

European Journal of Cancer

Volumn 35, Issue 5, 1999, Pages 850-858

  Sham, E ^a   Durand, R E ^b  

^a BRITISH COLUMBIA CANCER AGENCY   (Canada)

^b BRITISH COLUMBIA CANCER RESEARCH CENTRE   (Canada)

Author keywords

Accelerated repopulation; Cell kinetics; Predictive assays; Radiotherapy; T(pot); Xenografts

Indexed keywords

DNA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL KINETICS; CELL LOSS; CELL POPULATION; CONTROLLED STUDY; DNA CONTENT; FLOW CYTOMETRY; HUMAN; HUMAN TISSUE; MOUSE; NONHUMAN; PRIORITY JOURNAL; RADIATION DOSE FRACTIONATION; TREATMENT PLANNING; TUMOR GROWTH; TUMOR VOLUME; TUMOR XENOGRAFT; UTERINE CERVIX CARCINOMA;

ANIMALS; CARCINOMA, SQUAMOUS CELL; CELL DIVISION; FEMALE; MICE; MICE, SCID; TRANSPLANTATION, HETEROLOGOUS; TUMOR CELLS, CULTURED; UTERINE CERVICAL NEOPLASMS;

EID: 0032999604     PISSN: 09598049     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0959-8049(99)00019-2     Document Type: Article

References (33)

1. Withers H.R., Taylor J.M., Maciejewski B. The hazard of accelerated tumor clonogen repopulation during radiotherapy. Acta Oncol. 27:1988;131-146.
2. Allam A., Perez L.A., Huang P., et al. The effect of the overall treatment time of fractionated irradiation on the tumor control probability of a human soft tissue sarcoma xenograft in nude mice. Int. J. Radiat. Oncol. Biol. Phys. 32:1995;105-111.
3. Bentzen S.M., Thames H.D. Overall treatment time and tumor control dose for head and neck tumors: the dog leg revisited. Radiother. Oncol. 25:1992;143-144.
4. Duncan W., MacDougall R.H., Kerr G.R., Downing D. Adverse effect of treatment gaps in the outcome of radiotherapy for laryngeal cancer. Radiother. Oncol. 41:1996;203-207.
5. Fowler J.F., Lindstrom M.J. Loss of local control with prolongation in radiotherapy. Int. J. Radiat. Oncol. Biol. Phys. 23:1992;457-467.
6. Fyles A.W., Keane T.J., Barton M., Simm J. The effect of treatment duration in the local control of cervix cancer. Radiother. Oncol. 25:1992;273-279.
7. Hansen O., Overgaard J., Hansen H.S., et al. Importance of overall treatment time for the outcome of radiotherapy of advanced head and neck carcinoma: dependency on tumor differentiation. Radiother. Oncol. 43:1997;47-51.
8. Peters L.J., Withers H.R. Applying radiobiological principles to combined modality treatment of head and neck cancerthe time factor. Int. J. Radiat. Oncol. Biol. Phys. 39:1997;831-836.
9. Withers H.R., Peters L.J., Taylor J.M., et al. Local control of carcinoma of the tonsil by radiation therapy: an analysis of patterns of fractionation in nine institutions. Int. J. Radiat. Oncol. Biol. Phys. 33:1995;549-562.
10. Bourhis J., Wibault P., Lusinchi A., Bobin S., Luboinski B., Eschwege F. Status of accelerated fractionation radiotherapy in head and neck squamous cell carcinomas. Curr. Opin. Oncol. 9:1997;262-266.
11. Maciejewski B., Majewski S. Dose fractionation and tumour repopulation in radiotherapy for bladder cancer. Radiother. Oncol. 21:1991;163-170.
12. Roberts S.A., Hendry J.H. The delay before onset of accelerated tumour cell repopulation during radiotherapy: a direct maximum-likelihood analysis of a collection of worldwide tumour-control data. Radiother. Oncol. 29:1993;69-74.
13. Trott K.R., Kummermehr J. Rapid repopulation in radiotherapy: a debate on mechanism. Accelerated repopulation in tumours and normal tissues. Radiother. Oncol. 22:1991;159-160.
14. Fowler J.F. The phantom of tumor treatmentcontinually rapid proliferation unmasked. Radiother. Oncol. 22:1991;156-158.
15. Kummermehr J., Dorr W., Trott K.R. Kinetics of accelerated repopulation in normal and malignant squamous epithelia during fractionated radiotherapy. Br. J. Radiol. 24:1992;193-199.
16. Dubben H.H. No clinical evidence for the influence of overall treatment time on TCD50 of head and neck tumours. Radiother. Oncol. 25:1992;142-143.
17. Lai P.P., Pilepich M.V., Krall J.M., et al. The effect of overall treatment time on the outcome of definitive radiotherapy for localized prostate carcinoma: the Radiation Therapy Oncology Group 75-06 and 77-06 experience. Int. J. Radiat. Oncol. Biol. Phys. 21:1991;925-933.
18. pot! Int. J. Radiat. Oncol. Biol. Phys. 32:1995;1539-1541.
19. Hoyer M., Jorgensen K., Bundgaard T., et al. Lack of predictive value of potential doubling time and iododeoxyuridine labelling index in radiotherapy of squamous cell carcinoma of the head and neck. Radiother. Oncol. 46:1998;147-155.
20. pot in cancer of the uterine cervix: correlation between two laboratories and preliminary clinical results. Int. J. Radiat. Oncol. Biol. Phys. 32:1995;1319-1329.
21. Sham E., Durand R.E. Cell kinetics and repopulation mechanisms during multifraction irradiation of spheroids. Radiother. Oncol. 46:1998;201-207.
22. Sham E, Durand RE. Repopulation characteristics and cell kinetic parameters resulting from multifraction irradiation of xenograft tumors in SCID mice. Int J Radiat Oncol Biol Phys 1999, 43, 617-622.
23. Friedl F., Kimura I., Osato T., Ito Y. Studies on a new human cell line (SiHa) derived from carcinoma of uterus. I. Its establishment and morphology. Proc. Soc. Exptl. Biol. Med. 135:1970;543-545.
24. Begg A.C., McNally N.J., Shrieve D.C., Kärcher H. A method to measure the duration of DNA synthesis and the potential doubling time from a single sample. Cytometry. 6:1985;620-626.
25. White R.A., Terry N.H.A., Meistrich M.L., Calkins D.P. Improved method for computing potential doubling time from flow cytometric data. Cytometry. 11:1990;314-317.
26. pot in heterogeneous systems: a new approach illustrated with multicell spheroids. Cytometry. 14:1993;527-534.
27. Steel GG. Growth Kinetics of Tumours. Oxford, Oxford University Press, 1977.
28. Durand R.E. Tumor repopulation during radiotherapy: quantitation in two xenografted human tumors. Int. J. Radiat. Oncol. Biol. Phys. 39:1997;803-808.
29. Eschwege F., Bourhis J., Girinski T., et al. Predictive assays of radiation response in patients with head and neck squamous cell carcinoma: a review of the Institute Gustave Roussy experience. Int. J. Radiat. Oncol. Biol. Phys. 39:1997;849-853.
30. Begg A.C., Hofland I., Kummermehr J. Tumour cell repopulation during fractionated radiotherapy: correlation between flow cytometric and radiobiological data in three murine tumours. Eur. J. Cancer. 27:1991;537-543.
31. Hansen O., Grau C., Bentzen S.M., Overgaard J. Repopulation in the SCCVII squamous cell carcinoma assessed by an in vivoin vitro excision assay. Radiother. Oncol. 39:1996;137-144.
32. LaRue S.M., Fox M.H., Withrow S.J., et al. Impact of heterogeneity in the predictive value of kinetic parameters in canine osteosarcoma. Cancer Res. 54:1994;3916-3921.
33. Speke A.K., Hill R.P. Repopulation kinetics during fractionated irradiation and the relationship to the potential doubling time, Tpot. Int. J. Radiat. Oncol. Biol. Phys. 31:1995;847-856.