Reduced tumor necrosis factor-α and transforming growth factor-β1 expression in the lungs of inbred mice that fail to develop fibroproliferative lesions consequent to asbestos exposure

American Journal of Pathology

Volumn 154, Issue 3, 1999, Pages 853-862

  Brass, David M ^a   Hoyle, Gary W ^a   Poovey, Halet G ^a   Liu, Jing Yao ^a   Brody, Arnold R ^a  

^a TULANE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ASBESTOS FIBER; BROXURIDINE; MESSENGER RNA; TRANSFORMING GROWTH FACTOR BETA1; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASBESTOSIS; BRONCHIOLE; CONTROLLED STUDY; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; INBRED STRAIN; LUNG ALVEOLUS EPITHELIUM; LUNG ALVEOLUS MACROPHAGE; LUNG DEPOSIT; LUNG FIBROSIS; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION;

EID: 0032997844     PISSN: 00029440     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0002-9440(10)65332-1     Document Type: Article

References (41)

1. Selikoff IJ, Lee DH: Asbestos and Disease. New York, Academic Press, 1978
2. Crystal RG: Interstitial lung disease: current concepts of pathogenesis, staging and therapy. Am J Med 1981, 70:542-565
3. Crouch E: Pathobiology of pulmonary fibrosis. Am J Physiol 1990, 259:L159-L184
4. Morris GF, Brody AR: Molecular mechanisms of particle-induced lung disease. Environmental and Occupational Medicine. Edited by Rom WN. Philadelphia, Lippincott-Raven, 1998, pp 305-333
5. Yi ES, Lee H, Yin S, Piguet P, Sarosi I, Kaufmann S, Tarpley J, Wang N-S, Ulich TR: Platelet-derived growth factor causes pulmonary cell proliferation and collagen deposition in vivo. Am J Pathol 1996, 149: 539-548
6. Liu J-Y, Morris GF, Lei W-H, Hart CE, Lasky JA, Brody AR: Rapid activation of PDGF-A and -B expression at sites of lung injury in asbestos-exposed rats. Am J Respir Cell Mol Biol 1997, 17:129-140
7. Perdue TD, Brody AR: Distribution of transforming growth factor-β1, fibronectin, and smooth muscle actin in asbestos-induced pulmonary fibrosis in rats. J Histochem Cytochem 1994, 42:1061-1070
8. Piguet PF, Collart MA, Grau GE, Sappino A-P, Vassili P: Requirement of tumor necrosis factor for development of silica-induced pulmonary fibrosis. Nature 1990, 344:245-247
9. Kelly J: Cytokines of the lung. Am Rev Respir Dis 1990, 141:765-788
10. Brody AR, Hill LH, Adkins B, O'Connor R: Chrysotile asbestos inhalation in rats: deposition pattern and reaction of alveolar epithelium and pulmonary macrophages. Am Rev Respir Dis 1981, 123:670-679
11. Brody AR: Asbestos induced lung disease. Environ Health Perspect 1993, 100:21-30
12. Brody AR: Asbestos exposure as a model of inflammation inducing interstitial pulmonary fibrosis. Inflammation: Basic Principles and Clinical Correlates. Edited by Gallin JI, Goldstein IM, Snyderman R. New York, Raven Press, 1992, pp 1033-1049
13. Brody AR, Roe MW: Deposition pattern of inorganic particles at the alveolar level in the lungs of rats and mice. Am Rev Respir Dis 1983, 128:724-729
14. Miyazaki Y, Araki K, Vesin C, Garcia I, Kapanci Y, Whitsett JA, Piguet P-F, Vassalli P: Expression of a tumor necrosis factor-α transgene in murine lung causes lymphocytic and fibrosing alveolitis. J Clin Invest 1995, 96:250-259
15. Ray P, Tang W, Wang P, Homer R, Kuhn C III, Flavell RA, Elias JA: Regulated overexpression of interleukin 11 in the lung: use to dissociate development-dependent and -independent phenotypes. J Clin Invest 1997, 100:2501-2511
16. Zhou L, Dey CR, Wert SE, Whitsett JA: Arrested lung morphogenesis in transgenic mice bearing an SP-C-TGF-β1 chimeric gene. Dev Biol 1996, 175:227-238
17. Boström H, Willetts K, Pekny M, Levéen P, Lindahl P, Hedstrand H, Pekna M, Hellström M, Gebre-Medhin S, Schalling M, Nilsson M, Kurland S, Törnell J, Heath JK, Betsholtz C: PDGF-A signaling is a critical event in lung alveolar myofibroblast development and alveogenesis. Cell 1996, 85:863-873
18. Kulkarni AB, Ward JM, Yaswen L, Mackall CL, Bauer SR, Huh C-G, Gress RE, Karlsson S: Transforming growth factor-β1 null mice: an animal model for inflammatory disorders. Am J Pathol 1995, 146:264-275
19. Lee JJ, McGarry MP, Farmer SC, Denzler KL, Larson DA, Carrigan PE, Brenneise IE, Horton MA, Haczku A, Gelfand EW, Leikauf GD, Lee NA: Interleukin-5 expression in the lung epithelium of transgenic mice leads to pulmonary changes pathognomonic of asthma. J Exp Med 1997, 185:2143-2156
20. Pinkerton KE, Brody AR, McLaurin DA, Adkins B, O'Connor RW, Pratt PC, Crapo JD: Characterization of three types of chrysotile asbestos after aerosolization. Environ Res 1983, 31:32-53
21. Fermin CD, Degraw S: Colour thresholding in video imaging. J Anat 1995, 186:469-481
22. Eller P, Cassinelli M: NIOSH Manual of Analytical Methods, DHHS publication 94-113, ed 4. Washington, DC, Department of Health and Human Services, 1994
23. Liu J-Y, Morris GF, Lei W-H, Corti M, Brody AR: Up-regulated expression of transforming growth factor-α in the bronchiolar-alveolar duct regions of asbestos-exposed rats. Am J Pathol 1996, 149:205-217
24. Gardner SY, Brody AR: Incorporation of bromodeoxyuridine as a method to quantify cell proliferation in bronchiolar-alveolar duct regions of asbestos-exposed mice. Inhal Toxicol 1995, 7:215-224
25. Pelton RW, Johnson MD, Perkett EA, Gold LI, Moses HL: Expression of transforming growth factor-β1, -β2, and -β3 and protein in the murine lung. Am J Respir Cell Mol Biol 1991, 5:522-530
26. Coin PG, Osornio-Vargas AR, Roggli VL, Brody AR: Pulmonary fibrogenesis after three consecutive inhalation exposures to chrysotile asbestos. Am J Respir Crit Care Med 1996, 154:1511-1519
27. Chang LY, Overby LH, Brody AR, Crapo JD: Progressive lung cell reactions and extracellular matrix production after a brief exposure to asbestos. Am J Pathol 1988, 131:156-170
28. Doetschman TC, Eistetter H, Katz M, Schmidt W, Kemler R The in vitro development of blastocyst-derived embryonic stem cell lines: formation of visceral yolk sac, blood islands and myocardium. J Embryol Exp Morphol 1985, 87:27-45
29. McMahon AP, Bradley A: The Wnt-1 (int-1) proto-oncogene is required for development of a large region of the mouse brain. Cell 1990, 62:1073-1085
30. Dixon D, Bowser AD, Badgett A, Haseman JK, Brody AR: Incorporation of bromodeoxyuridine (BrdU) in the bronchiolar-alveolar regions of the lungs following two inhalation exposures to chrysotile asbestos in strain A/J mice. J Environ Pathol Toxicol Oncol 1995, 14:205-213
31. Raines EW, Ross R: Platelet-derived growth factor. I. High yield purification and evidence for multiple forms. J Biol Chem 1982, 257: 5154-5160
32. Derynck R: The physiology of transforming growth factor-α. Adv Cancer Res 1992, 58:27-52
33. Pelton RW, Moses HL: The β-type transforming growth factors, mediators of cell regulation in the lung. Am Rev Respir Dis 1990, 142: 31-35
34. Moses HL, Tucker RF, Leof EB, Coffey RJ, Halper J Jr, Shipley GD: Type β transforming growth factor is a growth stimulator and a growth inhibitor. Growth Factors and Transformation. Edited by Feramisco J, Ozanne B, Stiles B. Cold Spring Harbor, NY, Cold Spring Harbor Laboratory Press, 1985, pp 65-71
35. Centrella M, McCarthy TL, Canalis E: Transforming growth factor β is a bifunctional regulator of replication and collagen synthesis in osteoblast-enriched cell cultures from fetal rat bone. J Biol Chem 1987, 262:2869-2874
36. Brody AR, Roe MW, Evans JN, Davis GS: Deposition and translocation of inhaled silica in rats Lab Invest 1982, 47:533-542
37. Pinkerton KE, Dodge DE, Cederdahl-Demmler J, Wong VJ, Peake J, Haselton CJ, Mellick PW, Sing G, Plopper CG: Differentiated bronchiolar epithelium in alveolar ducts of rats exposed to ozone for 20 months. Am J Pathol 1993, 142:946-956
38. Sime PJ, Marr RA, Gauldie D, Xing Z, Hewlett BR, Graham FL, Gauldie J: Transfer of tumor necrosis factor-α to rat lung induces severe pulmonary inflammation and patchy interstitial fibrogenesis with induction of transforming growth factor-β1 and myofibroblasts. Am J Pathol 1998, 153:825-832
39. Phan SH, Gharaee-Kermani M, McGarry B, Kunkel SL, Wolber FW: Regulation of rat pulmonary artery endothelial cell transforming growth factor-β production by IL-1β and tumor necrosis factor-α1. J Immunol 1992, 149:103-106
40. Liu J-Y, Hoyle GW, Brody AR: Tumor necrosis factor-α receptor knockout mice are protected from the fibroproliferative effects of inhaled asbestos fibers. Am J Pathol 1998, 153:1839-1847
41. Brass DM, Hoyle GW, Liu J-Y, Brody AR: Primary lung fibroblasts from mice resistant to the fibrogenic effects of asbestos exhibit reduced proliferative capacity in vitro. Am J Respir Crit Care Med 1998, 157: A246