Natural immunity and HIV disease progression

AIDS

Volumn 13, Issue 5, 1999, Pages 557-563

  Ullum, Henrik ^a   Cozzi Lepri, Alessandro ^b   Aladdin, Hassan ^a   Katzenstein, Terese ^a   Victor, Jette ^a   Phillips, Andrew N ^b   Gerstoft, Jan ^a   Skinhøj, Peter ^a   Pedersen, Bente Klarlund ^a  

^a Rigshospitalet   (Denmark)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

Cellular immunity; HIV; HIV RNA; Lymphokine activated killer cells; Natural history; Natural killer cells

Indexed keywords

CD16 ANTIGEN; CD4 ANTIGEN; CD56 ANTIGEN; VIRUS RNA;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; ARTICLE; DISEASE COURSE; FOLLOW UP; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; LYMPHOCYTE COUNT; LYMPHOKINE ACTIVATED KILLER CELL; MAJOR CLINICAL STUDY; NATURAL KILLER CELL; PATHOGENESIS; PRIORITY JOURNAL; PROSPECTIVE STUDY; T LYMPHOCYTE; VIRUS IMMUNITY;

CD4 LYMPHOCYTE COUNT; DISEASE PROGRESSION; HIV INFECTIONS; HIV-1; HUMANS; IMMUNITY, NATURAL; KILLER CELLS, LYMPHOKINE-ACTIVATED; KILLER CELLS, NATURAL; VIRAL LOAD;

EID: 0032990486     PISSN: 02699370     EISSN: None     Source Type: Journal    
DOI: 10.1097/00002030-199904010-00004     Document Type: Article

References (25)

1. 1. Gryllis C, Wainberg MA, Gornitsky M, Brenner B: Diminution of inducible lymphokine-activated killer cell activity in individuals with AIDS-related disorders. AIDS 1990, 4 ; 1205-1212.
2. 2. Ullum H, Gøtzsche PC, Victor J, Dickmeiss E, Skinhøj P, Pedersen BK: Defective natural immunity - an early manifestation of human immunodeficiency virus infection. J Exp Med 1995, 182 ; 789-800.
3. 3. O'Shea J, Ortaldo JR: The biology of natural killer cells: insights into the molecular basis of function. In The Natural Killer Cell. Edited by Lewis CE, McGee J. Oxford: Oxford University Press, 1992 : 1-40.
4. 4. Ljunggren HG, Karre K: In search of the 'missing self'; MHC molecules and NK cell recognition. Immunol Today 1990, 11 : 237-244.
5. 5. Moretta L, Ciccone E, Mingari MC, Biassoni R, Moretta A: Human natural killer cells: origin, clonality, specifity and receptors. Adv Immunol 1995, 55:341-380.
6. 6. Trinchieri G: Biology of natural killer cells. Adv Immunol 1989, 47 ; 187-376.
7. 7. Welsh RM: Regulation of virus infections by natural killer cells. A review. Nat Immun Cell Growth Regul 1986, 5 : 169-199.
8. 8. Grimm EA, Mazumder A, Zhang HZ, Rosenberg SA: Lymphokine-activated killer cell phenomenon. Lysis of natural killer-resistant fresh solid tumor cells by interleukin 2-activated autologous human peripheral blood lymphocytes. J Exp Med 1982, 155: 1823-1841.
9. 9. Bonavida B, Katz J, Gottlieb M: Mechanism of defective NK cell activity in patients with acquired immunodeficiency syndrome (AIDS) and AIDS-related complex. Defective trigger on NK cells for NKCF production by target cells, and partial restoration by IL-2. J Immunol 1986, 137 : 1157-1163.
10. 10. Cai Q, Huang XL, Rappocciolo G, Rinaldo CRJ: Natural killer cell responses in homosexual men with early HIV infection. J Acquir Immune Defic Syndr 1990, 3 : 669-676.
11. 11. Ullum H, Katzenstein T, Gerstoft I, Skinhøj P, Pederen BK: Low levels of natural immunity is related to high levels of HIV RNA in plasma of HIV infected individuals. AIDS Res Hum Retroviruses 1996, 13 : 255-256.
12. 12. Collins KL, Chen BK, Kalams SA, Walker BD, Baltimore D: HIV-1 Nef protein protects infected primary cells against killing by cytotoxic T lymphocytes. Nature 1998, 391 : 397-401.
13. 13. Schwartz O, Marechal V, Le Gall S, Lemonnier F, Hedfors E: Endocytosis of major histocompability complex class I molecules is induced by the HIV-1 Nef protein. Nat Med 1996, 2 : 338-342.
14. 14. Phillips AN, Pezzotti P, Cozzi Lepri A, Rezza G: CD4 lymphocyte count as a determinant of the time from HIV seroconversion to AIDS and death from AIDS: evidence from the Italian Seroconversion Study. AIDS 1994, 8 : 1299-1305.
15. 15. Mellors JW, Rinaldo Jr CR, Gupta P, White RM, Todd JA, Kingsley LA: Prognosis in HIV-1 infection predicted by the quantify of virus in plasma. Science 1996, 272 : 1167-1170.
16. 16. Pezzotti P, Phillips AN, Dorrucci M et al.: Category of exposure to HIV and age in the progression to AIDS: longitudinal study of 1199 people with known dates of seroconversion. HIV Italian Seroconversion Study Group. BMJ 1996, 313 : 583-586.
17. 17. Pross HF, Baines MG, Rubin P, Shragge P, Patterson MS: Spontaneous human lymphocyte-mediated cytotoxicity against tumor target cells. The quantitation of natural killer cell activity. J Clin Immunol 1981, 1 : 51-63.
18. 18. Skibber JM, Lotze MT, Muul LM, Uppenkamp IK, Ross W, Rosenberg SA: Human lymphokine-activated killer cells: further isolation and characterization of the precursor and effector cell. Nat Immun Cell Growth Regul 1987, 6 : 291-305.
19. 19. Skowron G, Cole BF, Zheng D, Accetta G, Yen-Lieberman B: gp120-directed antibody-dependent cellular cytotoxicity as a major determinant of the rate of decline in CD4 percentage in HIV-1 disease. AIDS 1997, 11 : 1807-1814.
20. 20. Jewett A, Cavalcanti M, Giorgi J, Bonavida B: Concomitant killing in vitro of both gp120-coated CD4+ peripheral T lymphocytes and natural killer cells in the antibody-dependent cellular cytotoxicity (ADCC) system. J Immunol 1997, 158 : 5492-5500.
21. 21. Bruunsgaard H, Pedersen C, Skinhøj P, Pedersen BK: Clinical progression of HIV infection: role of NK cells. Scand J Immunol 1997, 46 : 91-95.
22. 22. Ahmad A, Morisset R, Thomas R, Menezes J: Evidence for a defect of antibody-dependent cellular cytotoxic (ADCC) effector function and anti-HIV gp120/41-specific ADCC mediating antibody titres in HIV-infected individuals. J Acquir Immune Defic Syndr 1994, 7 ; 428-437.
23. 23. Rappocciolo G, Toso JF, Torpey DJ, Gupta P, Rinaldo CRJ: Association of alpha interferon production with natural killer cell lysis of U937 cells infected with human immunodeficiency virus. J Clin Microbiol 1989, 27 : 41-48.
24. 24. Hofmann B, Lindhardt BO, Gerstoft J et al.: Lymphocyte transformation response to pokeweed mitogen as a predictive marker for development of AIDS and AIDS related symptoms in homosexual men with HIV antibodies. Br Med J (Clin Res Ldn) 1987, 295 : 293-296.
25. 25. Roos MT, Miedema F, Koot M, et al.: T cell function in vitro is an independent progression marker for AIDS in human immunodeficiency virus-infected asymptomatic subjects. J Infect Dis 1995, 171 : 531-536.