Structural features of the central cannabinoid CB1 receptor involved in the binding of the specific CB1 antagonist SR 141716A

Journal of Biological Chemistry

Volumn 271, Issue 12, 1996, Pages 6941-6946

  Shire, David ^a   Calandra, Bernard ^a   Delpech, Monique ^a   Dumont, Xavier ^a   Kaghad, Mourad ^a   Le Fur, Gérard ^a   Caput, Daniel ^a   Ferrara, Pascual ^a  

^a SANOFI   (France)

Author keywords

[No Author keywords available]

Indexed keywords

4 (1,1 DIMETHYLHEPTYL) 1',2',3',4',5',6' HEXAHYDRO 2,3' DIHYDROXY 6' (3 HYDROXYPROPYL)BIPHENYL; CANNABINOID RECEPTOR; CHIMERIC PROTEIN; RIMONABANT;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; DRUG RECEPTOR BINDING; LIGAND BINDING; NONHUMAN; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION;

EID: 0029965292     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.271.12.6941     Document Type: Article

References (45)

1. Gaoni, Y., and Mechoulam, R. (1964) J. Am. Chem. Soc. 86, 1646-1647
2. Matsuda, L A , Lolait, S. J , Brownstein, M. J., Young, A. C., and Bonner, T. I. (1990) Nature 346, 561-564
3. Gérard, C. M., Mollereau, C., Vassart, G., and Parmentier, M. (1991) Biochem. J. 279, 129-134
4. Munro, S., Thomas, K. L , and Abu-Shaar, M. (1993) Nature 365, 61-65
5. Dohlman, H. G., Thorner, J., Caron, M. G., and Lefkowitz, R J. (1991) Annu. Rev. Biochem. 60, 653-688
6. Slipetz, D. M., O'Neill, G. P , Favreau, L., Dufresne, C., Gallant, M., Gareau, Y., Guay, D , Labelle, M., and Metters, K. M (1995) Mol. Pharmacol. 48, 352-361
7. Felder, C. C., Joyce, K. E., Briley, E. M., Mansouri, J., Mackie, K., Blond, O., Lai, Y., Ma, A. L., and Mitchell, R. L. (1995) Mol. Pharmacol. 48, 443-450
8. Devane, W. A., Hanus, L., Breuer, A., Pertwee, R. G , Stevenson, L. A., Griffin, G., Gibson, D., Mandelbaum, A , Etinger, A., and Mechoulam, R. (1992) Science 258, 1946-1949
9. Mechoulam, R., Ben-Shabat, S., Hanus, L., Ligumsky, M., Kaminski, N. E., Schatz, A. R., Gopher, A., Almog, S., Martin, B. R., Compton, D. R., Pertwee, R. G , Griffin, G., Beyewitch, M., Barg, J., and Vogel Z. (1995) Biochem. Pharmacol. 50, 83-90
10. Howlett, A. C. (1985) Mol. Pharmacol. 27, 429-436
11. Howlett, A. C., Qualy, J. M , and Khachatrian, L L. (1986) Mol. Pharmacol. 29, 307-313
12. Rinaldi-Carmona, M., Barth, F., Héaulme, M., Shire, D., Calandra, B., Congy, C , Martinez, S., Maruani, J , Néliat, G., Caput, D , Ferrara, P., Soubrié, P., Brelière, J.-C., and Le Fur, G (1994) FEBS Lett. 350, 240-244
13. Mackie, K., and Hille, B (1992) Proc. Natl. Acad. Sci. U S. A. 89, 3825-3829
14. Felder, C. C , Veluz, J. S., Williams, H. L., Briley, E M., and Matsuda, L. A. (1992) Mol. Pharmacol. 42, 838-845
15. Kobilka, B. K., Kobilka, T. S., Daniel, K., Regan, J. W., Caron, M. G., and Lefkowitz, R. J. (1988) Science 240, 1310-1316
16. Schwartz, T. W. (1994) Curr. Opin. Biotechnol. 5, 434-444
17. Strader, C D , Fong, T. M., Tota, M. R., Underwood, D., and Dixon, R. A. F. (1994) Annu. Rev Biochem 63, 101-132
18. Shire, D., Carillon, C., Kaghad, M., Calandra, B , Rinaldi-Carmona, M., Le Fur, G., Caput, D., and Ferrara, P. (1995) J Biol. Chem. 270, 3726-3731
19. Horton, R. M., Hunt, H. D., Ho, S. N., Pullen, J K., and Pease, L. R. (1989) Gene (Amst) 77, 61-68
20. Miloux, B., and Lupker, J. H. (1994) Gene (Amst.) 149, 341-344
21. Sanger, F., Nicklen, S , and Coulson, A. R (1977) Proc. Natl. Acad. Sci. U. S. A. 74, 5463-5467
22. Lupker, J. H., Roskam, W. G , Miloux, B., Liauzun, P., Yaniv, M., and Jouanneau, J. (1983) Gene (Amst.) 24, 281-287
23. Bradford, M. M (1976) Anal. Biochem 72, 248-254
24. Mouillac, B , Caron, M., Bonin, H., Dennis, M., and Bouvier, M. (1992) J. Biol. Chem. 267, 21733-21737
25. Pan, Y., Wilson, P , and Gitschier, J. (1994) J. Biol. Chem. 269, 31933-31937
26. Lu, R., Hubbard, J. R., Martin, B. R , and Kalimi, M Y. (1993) Mol. Cell. Biochem. 121, 119-126
27. Hillard, C. J., Edgemond, W. S., and Campbell, W. B. (1995) J. Neurochem. 64, 677-683
28. Davidson, F. F., Loewen, P C., and Khorana, H. G. (1994) Proc. Natl Acad. Sci. U. S A. 91, 4029-4033
29. Karnik, S S., Sakmar, T. P , Chen, H.-B., and Khorana, H. B. (1988) Proc. Natl. Acad. Sci. U S. A. 85, 8459-8463
30. Rinaldi-Carmona, M., Barth, F , Héaulme, M , Alonso, R., Shire, D., Congy, C., Soubrié, P., Breliere, J -C., and Le Fur, G (1995) Life Sci. 56, 1941-1947
31. Bramblett, R. D., Panu, A. M., Ballesteros, J. A., and Reggio, P. H. (1995) Life Sci. 56, 1971-1982
32. Baldwin, J. M. (1994) Curr. Opin. Cell Biol 6, 180-190
33. Schertler, G. F. X , Villa, C., and Henderson, R. (1993) Nature 362, 770-772
34. Fong, T. M., Yu, H., Cascieri, M. A., Underwood, D , Swain, C. J., and Strader, C. D (1994) J Biol. Chem. 269, 2728-2732
35. Sachais, B. S., Snider, R M , Lowe, J. A., III, and Krause, J. E. (1993) J. Biol. Chem 268, 2319-2323
36. Sachais, B. S., and Krause, J E (1994) Mol. Pharmacol. 46, 122-128
37. Xue, J -C , Chen, C., Zhu, J , Kunapuli, S., DeRiel, J K., Yu, L , and Liu-Chen, L -Y. (1994) J. Biol. Chem. 269, 30195-30199
38. Olah, M. E , Jacobson, K A , and Stiles, G L. (1994) J. Biol. Chem 269, 24692-24698
39. Pittel, Z., and Wess, J. (1994) Mol. Pharmacol. 45, 61-64
40. Suryanarayana, S., Von Zastrow, M , and Kobilka, B. K. (1992) J. Biol. Chem. 267, 21991-21994
41. Zhou, W., Flanagan, C , Ballesteros, J. A., Konvicka, K., Davidson, J. S., Weinstein, H., Millar, R. P., and Sealfon, S. C. (1994) Mol. Pharmacol. 45, 165-170
42. Kozell, L. B., Machida, C. A., Neve, R. L., and Neve, K. A. (1994) J. Biol. Chem. 269, 30299-30306
43. Hurtley, S. M., and Helenius, A. (1989) Annu. Rev. Cell Biol 5, 277-307
44. Rinaldi-Carmona, M., Pialot, F., Congy, C., Barth, F., Brelière, J.-C., and Le Fur, G (1995) abstract in 1995 ICRS Symposium on Cannabis and the Cannabinoids, Scottsdale, Arizona
45. Bramblett, R. D. and Reggio, P. H. (1995) abstract in 1995 ICRS Symposium on Cannabis and the Cannabinoids, Scottsdale, Arizona