메뉴 건너뛰기




Volumn 13, Issue 1, 1999, Pages

Combination therapy containing ritonavir plus saquinavir has superior short-term antiretroviral efficacy: A randomized trial

Author keywords

Efficacy; Indinavir; Randomized controlled trial; Ritonavir; Safety; Saquinavir

Indexed keywords

INDINAVIR; NUCLEOSIDE ANALOG; RITONAVIR; SAQUINAVIR; VIRUS RNA;

EID: 0032988176     PISSN: 02699370     EISSN: None     Source Type: Journal    
DOI: 10.1097/00002030-199901140-00002     Document Type: Article
Times cited : (90)

References (20)
  • 1
    • 0007010412 scopus 로고    scopus 로고
    • Antiretroviral therapy for HIV infection in 1998: Updated recommendations of the International AIDS Society - USA Panel
    • 1. Carpenter CCJ, Fischl MA, Hammer SM, et al.: Antiretroviral therapy for HIV infection in 1998: updated recommendations of the International AIDS Society - USA Panel. JAMA 1998, 280:78-86.
    • (1998) JAMA , vol.280 , pp. 78-86
    • Carpenter, C.C.J.1    Fischl, M.A.2    Hammer, S.M.3
  • 2
    • 0032566194 scopus 로고    scopus 로고
    • 1998 Revision to the British HIV Association guidelines for antiretroviral treatment of HIV seropositive individuals
    • 2. Gazzard B, Moyle G: 1998 revision to the British HIV Association guidelines for antiretroviral treatment of HIV seropositive individuals, Lancet 1998, 352:314-316.
    • (1998) Lancet , vol.352 , pp. 314-316
    • Gazzard, B.1    Moyle, G.2
  • 3
    • 7844246144 scopus 로고    scopus 로고
    • Changes in use of antiretroviral therapy in regions of Europe over time
    • 3. Kirk O, Mocroft A, Katzenstein TL, et al., for the EuroSIDA study group: Changes in use of antiretroviral therapy in regions of Europe over time. AIDS 1998, 12:2031-2039.
    • (1998) AIDS , vol.12 , pp. 2031-2039
    • Kirk, O.1    Mocroft, A.2    Katzenstein, T.L.3
  • 4
    • 6844240219 scopus 로고    scopus 로고
    • Randomised placebo-controlled trial of ritonavir in advanced HIV-1 disease
    • 4. Cameron DW, Heath-Chiossi M, Danner S, et al., for the Advanced HIV Disease Ritonavir Study Group: Randomised placebo-controlled trial of ritonavir in advanced HIV-1 disease. Lancet 1998, 351:543-549.
    • (1998) Lancet , vol.351 , pp. 543-549
    • Cameron, D.W.1    Heath-Chiossi, M.2    Danner, S.3
  • 5
    • 0442268112 scopus 로고    scopus 로고
    • A controlled trial of two nucleoside analogues plus indinavir in persons with human immunodeficiency virus infection and CD4 cell counts of 200 per cubic millimeter or less
    • 5. Hammer SM, Squires KE, Hughes MD, et al., for the AIDS Group 320 Study Team: A controlled trial of two nucleoside analogues plus indinavir in persons with human immunodeficiency virus infection and CD4 cell counts of 200 per cubic millimeter or less. N Engl J Med 1997, 336:725-73.
    • (1997) N Engl J Med , vol.336 , pp. 725-773
    • Hammer, S.M.1    Squires, K.E.2    Hughes, M.D.3
  • 6
    • 0030869269 scopus 로고    scopus 로고
    • Treatment with indinavir, zidovudine, and lamivudine in adults with human immunodeficiency virus infection and prior antiretroviral therapy
    • 6. Gulick RM, Mellors JVV, Havlir D, et al.: Treatment with indinavir, zidovudine, and lamivudine in adults with human immunodeficiency virus infection and prior antiretroviral therapy. N Engl J Med 1997, 337:734-739.
    • (1997) N Engl J Med , vol.337 , pp. 734-739
    • Gulick, R.M.1    Mellors, J.V.V.2    Havlir, D.3
  • 7
    • 2642709177 scopus 로고    scopus 로고
    • Declining morbidity and mortality among patients with advanced human immunodeficiency virus infection
    • 7. Paella FJ Jr, Delaney KM, Moorman AC, et al., and the HIV Outpatient Study Investigators: Declining morbidity and mortality among patients with advanced human immunodeficiency virus infection. N Engl J Med 1998, 338:853-860.
    • (1998) N Engl J Med , vol.338 , pp. 853-860
    • Paella F.J., Jr.1    Delaney, K.M.2    Moorman, A.C.3
  • 8
    • 9844261693 scopus 로고    scopus 로고
    • Impact of protease inhibitors on AIDS-defining events and hospitalizations in 10 French AIDS reference centres
    • 8. Mouton Y, Alfandari S, Valette M, et al., and the Fédération Nationale des Centres de Lutte contre le SIDA: Impact of protease inhibitors on AIDS-defining events and hospitalizations in 10 French AIDS reference centres. AIDS 1997, 11:F101-F105.
    • (1997) AIDS , vol.11
    • Mouton, Y.1    Alfandari, S.2    Valette, M.3
  • 9
    • 9844238154 scopus 로고    scopus 로고
    • Impact of new antiretroviral combination therapies in HIV infected patients in Switzerland: Prospective multicentre study
    • 9. Egger M, Hirschel B, Francioli P, et al., and the Swiss HIV Cohort Study: Impact of new antiretroviral combination therapies in HIV infected patients in Switzerland: prospective multicentre study. BMJ 1997, 315:1194-1199.
    • (1997) BMJ , vol.315 , pp. 1194-1199
    • Egger, M.1    Hirschel, B.2    Francioli, P.3
  • 10
    • 0032576426 scopus 로고    scopus 로고
    • Changing patterns of mortality in patients infected with HIV
    • 10. Mocroft A, Vella S, Benfield T, et al., for the EuroSIDA study group Changing patterns of mortality in patients infected with HIV. Lancet 1998, 352:1725-1730.
    • (1998) Lancet , vol.352 , pp. 1725-1730
    • Mocroft, A.1    Vella, S.2    Benfield, T.3
  • 11
    • 0344015847 scopus 로고    scopus 로고
    • Virological treatment failure of protease inhibitor therapy in an unselected cohort of HIV-infected patients
    • 11. Fätkenheuer G, Theisen A, Rockstroh J, et al.: Virological treatment failure of protease inhibitor therapy in an unselected cohort of HIV-infected patients AIDS 1997, 11:F113-F116.
    • (1997) AIDS , vol.11
    • Fätkenheuer, G.1    Theisen, A.2    Rockstroh, J.3
  • 13
    • 7144257182 scopus 로고    scopus 로고
    • Pharmacokinetic interactions between two immunodeficiency virus protease inhibitors, ritonavir and saquinavir
    • 13. Hsu A, Granneman GR, Cao G, et al: Pharmacokinetic interactions between two immunodeficiency virus protease inhibitors, ritonavir and saquinavir. Clin Pharmacol Ther 1998, 63:453-464.
    • (1998) Clin Pharmacol Ther , vol.63 , pp. 453-464
    • Hsu, A.1    Granneman, G.R.2    Cao, G.3
  • 14
    • 0031054507 scopus 로고    scopus 로고
    • Saquinavir pharmacokinetics alone and in combination with ritonavir in HIV-infected patients
    • 14. Merry C, Barry MG, Mulcahy F, et al.: Saquinavir pharmacokinetics alone and in combination with ritonavir in HIV-infected patients. AIDS 1997, 11:F29-F33.
    • (1997) AIDS , vol.11
    • Merry, C.1    Barry, M.G.2    Mulcahy, F.3
  • 16
    • 0032500125 scopus 로고    scopus 로고
    • Activity of a ritonavir plus saquinavir-containing regimen in patients with virologic evidence of indinavir or ritonavir failure
    • 16. Decks SG, Grant RM, Beatty GW, Horton C, Detmer J, Eastman S. Activity of a ritonavir plus saquinavir-containing regimen in patients with virologic evidence of indinavir or ritonavir failure. AIDS 1998, 12:F97-F102.
    • (1998) AIDS , vol.12
    • Decks, S.G.1    Grant, R.M.2    Beatty, G.W.3    Horton, C.4    Detmer, J.5    Eastman, S.6
  • 17
    • 0032537171 scopus 로고    scopus 로고
    • The antiviral effect of ritonavir and saquinavir in combination amongst HIV-infected adults: Results from a community-based study
    • 17. Rhone SA, Hogg RS, Yip B, et al.: The antiviral effect of ritonavir and saquinavir in combination amongst HIV-infected adults: results from a community-based study AIDS 1998, 12:619-624.
    • (1998) AIDS , vol.12 , pp. 619-624
    • Rhone, S.A.1    Hogg, R.S.2    Yip, B.3
  • 18
    • 0027122957 scopus 로고
    • 1993 Revised classification system for HIV infection and expanded surveillance case definition for AIDS among adolescents and adults
    • 18. Centers for Disease Control and Prevention: 1993 Revised classification system for HIV infection and expanded surveillance case definition for AIDS among adolescents and adults. MMWR 1992, 41:1-19.
    • (1992) MMWR , vol.41 , pp. 1-19
  • 19
    • 0013603912 scopus 로고    scopus 로고
    • Different analyses give highly variable estimates of HIV-1 RNA undetectability and log reduction in clinical trials
    • Geneva. June - July [abstract 42204]
    • 19. Hill A, Demasi R, Kuhn M, and Avanti Steering Committee: Different analyses give highly variable estimates of HIV-1 RNA undetectability and log reduction in clinical trials. 12th World AIDS Conference. Geneva. June - July 1998 [abstract 42204].
    • (1998) 12th World AIDS Conference
    • Hill, A.1    Demasi, R.2    Kuhn, M.3
  • 20
    • 15144357022 scopus 로고    scopus 로고
    • The duration of viral suppression during protease inhibitor therapy for HIV-1 infection is predicted by plasma HIV-1 RNA at the nadir
    • 20. Kempf DJ, Rode RA, Xu Y, et al.: The duration of viral suppression during protease inhibitor therapy for HIV-1 infection is predicted by plasma HIV-1 RNA at the nadir AIDS 1998, 12:F9-F14.
    • (1998) AIDS , vol.12
    • Kempf, D.J.1    Rode, R.A.2    Xu, Y.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.