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Volumn 58, Issue 2, 1999, Pages 120-128

Molecular analysis of microdissected de novo glioblastomas and paired astrocytic tumors

Author keywords

Astrocytic tumor progression; Formalin fixed paraffin embedded tissue; Heterogeneity; Microdissection; Molecular analysis

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR; PROTEIN P53; RECEPTOR PROTEIN;

EID: 0032986688     PISSN: 00223069     EISSN: None     Source Type: Journal    
DOI: 10.1097/00005072-199902000-00002     Document Type: Article
Times cited : (52)

References (39)
  • 2
    • 0024516807 scopus 로고
    • Cytologic composition of the untreated glioblastoma with implications for evaluation of needle biopsies
    • Burger PC, Kleihues P. Cytologic composition of the untreated glioblastoma with implications for evaluation of needle biopsies. Cancer 1989;63:2014-23
    • (1989) Cancer , vol.63 , pp. 2014-2023
    • Burger, P.C.1    Kleihues, P.2
  • 3
    • 0021878052 scopus 로고
    • Antigenic heterogeneity of human anaplastic gliomas and glioma-derived cell lines defined by monoclonal antibodies
    • Wikstrand CJ, Grahmann FC, McComb RD, Bigner DD. Antigenic heterogeneity of human anaplastic gliomas and glioma-derived cell lines defined by monoclonal antibodies. J Neuropathol Exp Neurol 1985;44:229-41
    • (1985) J Neuropathol Exp Neurol , vol.44 , pp. 229-241
    • Wikstrand, C.J.1    Grahmann, F.C.2    McComb, R.D.3    Bigner, D.D.4
  • 4
    • 0023175278 scopus 로고
    • Monoclonal antibodies against human astrocytomas and their reactivity pattern
    • Stavrou D, Keiditsch E, Schmidberger F, et al. Monoclonal antibodies against human astrocytomas and their reactivity pattern. J Neurol Sci 1987;80:205-20
    • (1987) J Neurol Sci , vol.80 , pp. 205-220
    • Stavrou, D.1    Keiditsch, E.2    Schmidberger, F.3
  • 6
    • 0026531917 scopus 로고
    • Molecular characterization of areas with low grade tumor or satellitosis in human malignant astrocytomas
    • Leenstra S, Troost D, Westerveld A, Bosch DA, Hulsebos TJM. Molecular characterization of areas with low grade tumor or satellitosis in human malignant astrocytomas. Cancer Res 1992;52: 1568-72
    • (1992) Cancer Res , vol.52 , pp. 1568-1572
    • Leenstra, S.1    Troost, D.2    Westerveld, A.3    Bosch, D.A.4    Hulsebos, T.J.M.5
  • 7
    • 0029026094 scopus 로고
    • Identical mutations of the p53 tumor suppressor gene in the gliomatous and the sarcomatous components of gliosarcomas suggest a common origin from glial cells
    • Biernat W, Aguzzi A, Sure U, Grant JW, Kleihues P, Hegi ME. Identical mutations of the p53 tumor suppressor gene in the gliomatous and the sarcomatous components of gliosarcomas suggest a common origin from glial cells. J Neuropathol Exp Neurol 1995; 54:651-56
    • (1995) J Neuropathol Exp Neurol , vol.54 , pp. 651-656
    • Biernat, W.1    Aguzzi, A.2    Sure, U.3    Grant, J.W.4    Kleihues, P.5    Hegi, M.E.6
  • 8
    • 0028799791 scopus 로고
    • Shared allelic losses on chromosomes 1p and 19q suggest a common origin of oligodendroglioma and oligoastrocytoma
    • Kraus JA, Koopmann J, Kaskel P, et al. Shared allelic losses on chromosomes 1p and 19q suggest a common origin of oligodendroglioma and oligoastrocytoma. J Neuropathol Exp Neurol 1995; 54:91-95
    • (1995) J Neuropathol Exp Neurol , vol.54 , pp. 91-95
    • Kraus, J.A.1    Koopmann, J.2    Kaskel, P.3
  • 9
    • 0030017885 scopus 로고    scopus 로고
    • Overexpression of the EGF receptor and p53 mutations are mutually exclusive in the evolution of primary and secondary glioblastomas
    • Watanabe K, Tachibana O, Sata K, Yonekawa Y, Kleihues P, Ohgaki H. Overexpression of the EGF receptor and p53 mutations are mutually exclusive in the evolution of primary and secondary glioblastomas. Brain Pathol 1996;6:217-23
    • (1996) Brain Pathol , vol.6 , pp. 217-223
    • Watanabe, K.1    Tachibana, O.2    Sata, K.3    Yonekawa, Y.4    Kleihues, P.5    Ohgaki, H.6
  • 10
    • 0029890378 scopus 로고    scopus 로고
    • Analysis of p53 mutation and epidermal growth factor receptor amplification in recurrent gliomas with malignant progression
    • Reifenberger J, Ring GU, Gies U, et al. Analysis of p53 mutation and epidermal growth factor receptor amplification in recurrent gliomas with malignant progression. J Neuropathol Exp Neurol 1996; 55:822-31
    • (1996) J Neuropathol Exp Neurol , vol.55 , pp. 822-831
    • Reifenberger, J.1    Ring, G.U.2    Gies, U.3
  • 11
    • 0023914874 scopus 로고
    • Gene amplification in malignant human gliomas: Clinical and histopathologic aspects
    • Bigner SH, Burger PC, Wong AJ, et al. Gene amplification in malignant human gliomas: Clinical and histopathologic aspects. J Neuropathol Exp Neurol 1988;47:191-205
    • (1988) J Neuropathol Exp Neurol , vol.47 , pp. 191-205
    • Bigner, S.H.1    Burger, P.C.2    Wong, A.J.3
  • 12
    • 10144241684 scopus 로고    scopus 로고
    • Lack of prognostic relevance of alterations in the epidermal growth factor receptor-transforming growth factor-a pathway in human astrocytic gliomas
    • Waha A, Baumann A, Wolf HK, et al. Lack of prognostic relevance of alterations in the epidermal growth factor receptor-transforming growth factor-a pathway in human astrocytic gliomas. J Neurosurg 1996;85:634-41
    • (1996) J Neurosurg , vol.85 , pp. 634-641
    • Waha, A.1    Baumann, A.2    Wolf, H.K.3
  • 13
    • 0028652269 scopus 로고
    • CDKN2 (p16/MTS1) gene deletion or CDK4 amplification occurs in the majority of glioblastomas
    • Schmidt EE, Ichimura K, Reifenberger G, Collins VP CDKN2 (p16/MTS1) gene deletion or CDK4 amplification occurs in the majority of glioblastomas. Cancer Res 1994;54:6321-24
    • (1994) Cancer Res , vol.54 , pp. 6321-6324
    • Schmidt, E.E.1    Ichimura, K.2    Reifenberger, G.3    Collins, V.P.4
  • 14
    • 0028897307 scopus 로고
    • Homozygous deletions of the multiple tumor suppressor gene 1 in the progression of human astrocytomas
    • Walker DG, Duan W, Popovic EA, Kaye AH, Tomlinson FH, Lavin M. Homozygous deletions of the multiple tumor suppressor gene 1 in the progression of human astrocytomas. Cancer Res 1995;55: 20-23
    • (1995) Cancer Res , vol.55 , pp. 20-23
    • Walker, D.G.1    Duan, W.2    Popovic, E.A.3    Kaye, A.H.4    Tomlinson, F.H.5    Lavin, M.6
  • 15
    • 0026710064 scopus 로고
    • Association of epidermal growth factor receptor gene amplification with loss of chromosome 10 in human glioblastoma multiforme
    • von Deimling A, Louis DN, von Ammon K, et al. Association of epidermal growth factor receptor gene amplification with loss of chromosome 10 in human glioblastoma multiforme. J Neurosurg 1992;77:295-301
    • (1992) J Neurosurg , vol.77 , pp. 295-301
    • Von Deimling, A.1    Louis, D.N.2    Von Ammon, K.3
  • 16
    • 0029024891 scopus 로고
    • Chromosome 10 deletion mapping in human gliomas: A common deletion region in 10q25
    • Rasheed BKA, Mclendon RE, Friedman HS, et al. Chromosome 10 deletion mapping in human gliomas: A common deletion region in 10q25. Oncogene 1995;10:2243-46
    • (1995) Oncogene , vol.10 , pp. 2243-2246
    • Rasheed, B.K.A.1    McLendon, R.E.2    Friedman, H.S.3
  • 17
    • 0031967883 scopus 로고    scopus 로고
    • Distinct patterns of deletion on 10p and 10q suggest involvement of multiple tumor suppressor genes in the development of astrocytic gliomas of different malignant grades
    • Ichimura K, Schmidt EE, Miyakawa A, Goike HM, Collins VP. Distinct patterns of deletion on 10p and 10q suggest involvement of multiple tumor suppressor genes in the development of astrocytic gliomas of different malignant grades. Genes Chromosomes Cancer 1998;22:9-15
    • (1998) Genes Chromosomes Cancer , vol.22 , pp. 9-15
    • Ichimura, K.1    Schmidt, E.E.2    Miyakawa, A.3    Goike, H.M.4    Collins, V.P.5
  • 18
    • 17144436629 scopus 로고    scopus 로고
    • Identification of a candidate tumour suppressor gene. MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers
    • Steck PA, Pershouse MA, Jasser SA, et al. Identification of a candidate tumour suppressor gene. MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers. Nat Genet 1997;15: 356-62
    • (1997) Nat Genet , vol.15 , pp. 356-362
    • Steck, P.A.1    Pershouse, M.A.2    Jasser, S.A.3
  • 19
    • 0030936323 scopus 로고    scopus 로고
    • PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer
    • Li J, Yen C, Liaw D, et al. PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer. Science 1997;275:1943-47
    • (1997) Science , vol.275 , pp. 1943-1947
    • Li, J.1    Yen, C.2    Liaw, D.3
  • 20
    • 0030879478 scopus 로고    scopus 로고
    • DMBT1, a new member of the SRCR superfamily. On chromosome 10q25.3-26.1 is deleted in malignant brain tumors
    • Mollenhauer J, Wiemann S, Scheurlen W, et al. DMBT1, a new member of the SRCR superfamily. on chromosome 10q25.3-26.1 is deleted in malignant brain tumors. Nat Genet 1997;17:32-40
    • (1997) Nat Genet , vol.17 , pp. 32-40
    • Mollenhauer, J.1    Wiemann, S.2    Scheurlen, W.3
  • 21
    • 7144223432 scopus 로고    scopus 로고
    • PTEN mutations in gliomas and glioneuronal tumors
    • Duerr EM, Rollbrocker B, Hayashi Y, et al. PTEN mutations in gliomas and glioneuronal tumors. Oncogene 1998;16:2259-64
    • (1998) Oncogene , vol.16 , pp. 2259-2264
    • Duerr, E.M.1    Rollbrocker, B.2    Hayashi, Y.3
  • 24
    • 0030839886 scopus 로고    scopus 로고
    • Loss of heterozygosity of chromosome 14q in low- and high-grade meningiomas
    • Tse JYM, Ng HK, Lau KM, Lo KW, Poon WS, Huang DP. Loss of heterozygosity of chromosome 14q in low- and high-grade meningiomas. Hum Pathol 1997;28:779-85
    • (1997) Hum Pathol , vol.28 , pp. 779-785
    • Tse, J.Y.M.1    Ng, H.K.2    Lau, K.M.3    Lo, K.W.4    Poon, W.S.5    Huang, D.P.6
  • 26
    • 0028832159 scopus 로고
    • Reliability of differential PCR for the detection of EGFR and MDM2 gene amplification in DNA extracted from FFPE glioma tissue
    • Hunter SB, Abbott K, Varma VA, Olson JJ, Barnett DW, James CD. Reliability of differential PCR for the detection of EGFR and MDM2 gene amplification in DNA extracted from FFPE glioma tissue. J Neuropathol Exp Neurol 1995;54:57-64
    • (1995) J Neuropathol Exp Neurol , vol.54 , pp. 57-64
    • Hunter, S.B.1    Abbott, K.2    Varma, V.A.3    Olson, J.J.4    Barnett, D.W.5    James, C.D.6
  • 27
    • 0026545619 scopus 로고
    • Analysis of gene amplification in archival tissue by differential polymerase chain reaction
    • Neubauer A, Neubauer B, He M, et al. Analysis of gene amplification in archival tissue by differential polymerase chain reaction. Oncogene 1992;7:1019-25
    • (1992) Oncogene , vol.7 , pp. 1019-1025
    • Neubauer, A.1    Neubauer, B.2    He, M.3
  • 28
    • 0028053095 scopus 로고
    • Paraffin section p53 protein immunohistochemistry in neuroectodermal tumors
    • Ng HK, Lo SY, Huang DP, Poon WS. Paraffin section p53 protein immunohistochemistry in neuroectodermal tumors. Pathology 1994;26:1-5
    • (1994) Pathology , vol.26 , pp. 1-5
    • Ng, H.K.1    Lo, S.Y.2    Huang, D.P.3    Poon, W.S.4
  • 29
    • 0030917734 scopus 로고    scopus 로고
    • Incidence and timing of p53 mutations during astrocytoma progression in patients with multiple biopsies
    • Watanabe K, Sato K, Biernat W, et al. Incidence and timing of p53 mutations during astrocytoma progression in patients with multiple biopsies. Clin Cancer Res 1997;3:523-30
    • (1997) Clin Cancer Res , vol.3 , pp. 523-530
    • Watanabe, K.1    Sato, K.2    Biernat, W.3
  • 33
    • 0028123442 scopus 로고
    • The p53 gene and protein in human brain tumors
    • Louis DN, The p53 gene and protein in human brain tumors. J Neuropathol Exp Neurol 1994;53:11-21
    • (1994) J Neuropathol Exp Neurol , vol.53 , pp. 11-21
    • Louis, D.N.1
  • 34
  • 37
    • 0023429079 scopus 로고
    • Increased expression of the epidermal growth factor receptor gene in malignant gliomas is invariabley associated with gene amplification
    • Wong AJ, Bigner SH, Bigner DD, Kinzler KW, Hamilton SR, Vogelstein B. Increased expression of the epidermal growth factor receptor gene in malignant gliomas is invariabley associated with gene amplification. Proc Natl Acad Sci USA 1987;84:6899-6903
    • (1987) Proc Natl Acad Sci USA , vol.84 , pp. 6899-6903
    • Wong, A.J.1    Bigner, S.H.2    Bigner, D.D.3    Kinzler, K.W.4    Hamilton, S.R.5    Vogelstein, B.6
  • 38
    • 0025790916 scopus 로고
    • Genes for epidermal growth factor receptor, transforming growth factor alpha, and epidermal growth factor and their expression in human glioma in vivo
    • Ekstrand AJ, James CD, Cavenee WK, Seliger B, Pettersson RF, Collins VP. Genes for epidermal growth factor receptor, transforming growth factor alpha, and epidermal growth factor and their expression in human glioma in vivo. Cancer Res 1991;51:2164-72
    • (1991) Cancer Res , vol.51 , pp. 2164-2172
    • Ekstrand, A.J.1    James, C.D.2    Cavenee, W.K.3    Seliger, B.4    Pettersson, R.F.5    Collins, V.P.6
  • 39
    • 0028885029 scopus 로고
    • Distribution of epidermal growth factor receptor gene amplification in brain tumours and correlation to prognosis
    • Diedrich U, Lucius J, Baron E, Behnke J, Pabst B, Zoll B. Distribution of epidermal growth factor receptor gene amplification in brain tumours and correlation to prognosis. J Neurol 1995;242:683-88
    • (1995) J Neurol , vol.242 , pp. 683-688
    • Diedrich, U.1    Lucius, J.2    Baron, E.3    Behnke, J.4    Pabst, B.5    Zoll, B.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.