-
1
-
-
0026088156
-
Differential regional haemodynamic effects of the non-peptide angiotensin II antagonist, DuP 753, in water-replete and water-deprived Brattleboro rats
-
BATIN, P., GARDINER, S.M., COMPTON, A.M. & BENNETT, T. (1991). Differential regional haemodynamic effects of the non-peptide angiotensin II antagonist, DuP 753, in water-replete and water-deprived Brattleboro rats. Life Sci., 48, 733-739.
-
(1991)
Life Sci.
, vol.48
, pp. 733-739
-
-
Batin, P.1
Gardiner, S.M.2
Compton, A.M.3
Bennett, T.4
-
2
-
-
0026641944
-
Aminoguanidine, a novel inhibitor of nitric oxide formation, prevents diabetic vascular dysfunction
-
CORBETT, J.A., TILTON, R.G., CHANG, K., HASAN, K.S., IDO, Y., WANG, J.L., SWEETLAND, M.A., LANCASTER JR, J.R., WILLIAMSON, J.R. & MCDANIEL, M.L. (1992). Aminoguanidine, a novel inhibitor of nitric oxide formation, prevents diabetic vascular dysfunction. Diabetes, 41, 552-556.
-
(1992)
Diabetes
, vol.41
, pp. 552-556
-
-
Corbett, J.A.1
Tilton, R.G.2
Chang, K.3
Hasan, K.S.4
Ido, Y.5
Wang, J.L.6
Sweetland, M.A.7
Lancaster Jr., J.R.8
Williamson, J.R.9
Mcdaniel, M.L.10
-
3
-
-
0028889173
-
In vivo pharmacological characterization of the non-peptide endothelin receptor antagonist SB 209670
-
DOUGLAS, S.A., EDWARDS, R.M., ELLIOTT, J.D. & OHLSTEIN, E.H. (1995a). In vivo pharmacological characterization of the non-peptide endothelin receptor antagonist SB 209670. Br. J. Pharmacol., 114, 405-413.
-
(1995)
Br. J. Pharmacol.
, vol.114
, pp. 405-413
-
-
Douglas, S.A.1
Edwards, R.M.2
Elliott, J.D.3
Ohlstein, E.H.4
-
4
-
-
0028944196
-
Antihypertensive actions of the novel nonpeptide endothelin receptor antagonist SB 209670
-
DOUGLAS, S.A., GELLAI, M., EZEKIEL, M., FEUERSTEIN, G.Z., ELLIOTT, J.D. & OHLSTEIN, E.H. (1995b). Antihypertensive actions of the novel nonpeptide endothelin receptor antagonist SB 209670. Hypertension, 25, 818-822.
-
(1995)
Hypertension
, vol.25
, pp. 818-822
-
-
Douglas, S.A.1
Gellai, M.2
Ezekiel, M.3
Feuerstein, G.Z.4
Elliott, J.D.5
Ohlstein, E.H.6
-
5
-
-
0024358568
-
Regional haemodynamic changes following hypovolemia in conscious rats
-
GARDINER, S.M., COMPTON, A.M. & BENNETT, T. (1989). Regional haemodynamic changes following hypovolemia in conscious rats. Am. J. Physiol., 256, R1076-R1083.
-
(1989)
Am. J. Physiol.
, vol.256
-
-
Gardiner, S.M.1
Compton, A.M.2
Bennett, T.3
-
6
-
-
0025235343
-
Control of regional blood flow by endothelium-derived nitric oxide
-
GARDINER, S.M., COMPTON, A.M., BENNETT, T., PALMER, R.M.J. & MONCADA, S. (1990a). Control of regional blood flow by endothelium-derived nitric oxide. Hypertension, 15, 486-492.
-
(1990)
Hypertension
, vol.15
, pp. 486-492
-
-
Gardiner, S.M.1
Compton, A.M.2
Bennett, T.3
Palmer, R.M.J.4
Moncada, S.5
-
7
-
-
0025123927
-
G-nitro-L-arginine methyl ester in conscious, Long Evans rats
-
G-nitro-L-arginine methyl ester in conscious, Long Evans rats. Br. J. Pharmacol., 101, 625-631.
-
(1990)
Br. J. Pharmacol.
, vol.101
, pp. 625-631
-
-
Gardiner, S.M.1
Compton, A.M.2
Kemp, P.A.3
Bennett, T.4
-
9
-
-
0027400550
-
Effects of chronic treatment with nitric oxide synthase inhibitors on regional haemodynamic responses to vasodilators in conscious Brattleboro rats
-
GARDINER, S.M., KEMP, P.A. & BENNETT, T. (1993). Effects of chronic treatment with nitric oxide synthase inhibitors on regional haemodynamic responses to vasodilators in conscious Brattleboro rats. Br. J. Pharmacol., 109, 222-228.
-
(1993)
Br. J. Pharmacol.
, vol.109
, pp. 222-228
-
-
Gardiner, S.M.1
Kemp, P.A.2
Bennett, T.3
-
10
-
-
0029112423
-
Enhancement of the hypotensive and vasodilator effects of endotoxaemia in conscious rats by the endothelin antagonist, SB 209670
-
GARDINER, S.M., KEMP, P.A., MARCH, J.E. & BENNETT, T. (1995a). Enhancement of the hypotensive and vasodilator effects of endotoxaemia in conscious rats by the endothelin antagonist, SB 209670. Br. J. Pharmacol., 116, 1718-1719.
-
(1995)
Br. J. Pharmacol.
, vol.116
, pp. 1718-1719
-
-
Gardiner, S.M.1
Kemp, P.A.2
March, J.E.3
Bennett, T.4
-
11
-
-
0029164376
-
Cardiac and regional haemodynamics, inducible nitric oxide synthase (NOS) activity, and the effects of NOS inhibitors in conscious, endotoxaemic rats
-
GARDINER, S.M., KEMP, P.A., MARCH, J.E. & BENNETT, T. (1995b). Cardiac and regional haemodynamics, inducible nitric oxide synthase (NOS) activity, and the effects of NOS inhibitors in conscious, endotoxaemic rats. Br. J. Pharmacol., 116, 2005-2016.
-
(1995)
Br. J. Pharmacol.
, vol.116
, pp. 2005-2016
-
-
Gardiner, S.M.1
Kemp, P.A.2
March, J.E.3
Bennett, T.4
-
12
-
-
0029962321
-
Effects of dexamethasone and SB 209670 on the regional haemodynamic responses to lipopolysaccharide in conscious rats
-
in press
-
GARDINER, S.M., KEMP, P.A., MARCH, J.E. & BENNETT, T. (1996). Effects of dexamethasone and SB 209670 on the regional haemodynamic responses to lipopolysaccharide in conscious rats. Br. J. Pharmacol., (in press).
-
(1996)
Br. J. Pharmacol.
-
-
Gardiner, S.M.1
Kemp, P.A.2
March, J.E.3
Bennett, T.4
-
13
-
-
0028808769
-
Aminoguanidine selectively decreases cyclic GMP levels produced by inducible nitric oxide synthase
-
GRIFFITHS, M.J.D., MESSENT, M., CURZEN, N.P. & EVANS, T.W. (1995). Aminoguanidine selectively decreases cyclic GMP levels produced by inducible nitric oxide synthase. Am. J. Resp. Crit. Care Med., 152, 1599-1604.
-
(1995)
Am. J. Resp. Crit. Care Med.
, vol.152
, pp. 1599-1604
-
-
Griffiths, M.J.D.1
Messent, M.2
Curzen, N.P.3
Evans, T.W.4
-
14
-
-
0027141432
-
Aminoguanidine selectively inhibits inducible nitric oxide synthase
-
GRIFFITHS, M.J.D., MESSENT, M., MACALLISTER, R.J. & EVANS, T.W. (1993). Aminoguanidine selectively inhibits inducible nitric oxide synthase. Br. J. Pharmacol., 110, 963-968.
-
(1993)
Br. J. Pharmacol.
, vol.110
, pp. 963-968
-
-
Griffiths, M.J.D.1
Messent, M.2
Macallister, R.J.3
Evans, T.W.4
-
15
-
-
0019603363
-
Regional blood flow measurement with pulsed Doppler flowmeter in conscious rat
-
HAYWOOD, J.R., SHAFFER, R.A., FASTENOW, C., FINK, G.D. & BRODY, M.J. (1981). Regional blood flow measurement with pulsed Doppler flowmeter in conscious rat. Am. J. Physiol., 241, H273-H278.
-
(1981)
Am. J. Physiol.
, vol.241
-
-
Haywood, J.R.1
Shaffer, R.A.2
Fastenow, C.3
Fink, G.D.4
Brody, M.J.5
-
17
-
-
0026662385
-
Dexamethasone inhibits mitogen induction of the TIS10 prostaglandin synthase/cyclooxygenase gene
-
KUJUBU, D.A. & HERSCHMAN, H.R. (1992). Dexamethasone inhibits mitogen induction of the TIS10 prostaglandin synthase/cyclooxygenase gene. J. Biol. Chem., 267, 7991-7994.
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 7991-7994
-
-
Kujubu, D.A.1
Herschman, H.R.2
-
18
-
-
0025833001
-
Inhibition of diabetes-associated complications by nucleophilic compounds
-
KUMARI, K., UMAR, S., BANSAL, V. & SAHIB, M.K. (1991). Inhibition of diabetes-associated complications by nucleophilic compounds. Diabetes, 40, 1079-1084.
-
(1991)
Diabetes
, vol.40
, pp. 1079-1084
-
-
Kumari, K.1
Umar, S.2
Bansal, V.3
Sahib, M.K.4
-
19
-
-
0028843127
-
Aminoguanidine inhibits both constitutive and inducible nitric oxide synthase isoforms in rat intestinal microvasculaturc in vivo
-
LASZLO, F., EVANS, S.M. & WHITTLE, B.J.R. (1995). Aminoguanidine inhibits both constitutive and inducible nitric oxide synthase isoforms in rat intestinal microvasculaturc in vivo. Eur. J. Pharmacol., 272, 169-175.
-
(1995)
Eur. J. Pharmacol.
, vol.272
, pp. 169-175
-
-
Laszlo, F.1
Evans, S.M.2
Whittle, B.J.R.3
-
20
-
-
0028828569
-
Aminoguanidine-provoked leukocyte adherence to rat mcsenteric venules: Role of constitutive nitric oxide synthase inhibition
-
LOPEZ-BELMONTE, J. & WHITTLE, B.J.R. (1995). Aminoguanidine-provoked leukocyte adherence to rat mcsenteric venules: role of constitutive nitric oxide synthase inhibition. Br. J. Pharmacol., 116, 2710-2714.
-
(1995)
Br. J. Pharmacol.
, vol.116
, pp. 2710-2714
-
-
Lopez-Belmonte, J.1
Whittle, B.J.R.2
-
21
-
-
0027402115
-
Selective inhibition of the inducible nitric oxide synthase by aminoguanidine
-
MISKO, T.P., MOORE, W.M., KASTEN, T.P., NICKOLS, G.A., CORBETT, J.A., TILTON, R.G., MCDANIEL, M.L., WILLIAMSON, J.R. & CURRIE, M.G. (1993). Selective inhibition of the inducible nitric oxide synthase by aminoguanidine. Eur. J. Pharmacol., 233, 119-125.
-
(1993)
Eur. J. Pharmacol.
, vol.233
, pp. 119-125
-
-
Misko, T.P.1
Moore, W.M.2
Kasten, T.P.3
Nickols, G.A.4
Corbett, J.A.5
Tilton, R.G.6
Mcdaniel, M.L.7
Williamson, J.R.8
Currie, M.G.9
-
22
-
-
0028968360
-
Novel potent and selective inhibitors of inducible nitric oxide synthase
-
NAKANE, M., KLINGHOFER, V., KUK, J.E., DONNELLY, J.L., BUDZIK, G.P., POLLOCK, J.S., BASHA, F. & CARTER, G.W. (1995). Novel potent and selective inhibitors of inducible nitric oxide synthase. Mol. Pharmacol., 47, 831-834.
-
(1995)
Mol. Pharmacol.
, vol.47
, pp. 831-834
-
-
Nakane, M.1
Klinghofer, V.2
Kuk, J.E.3
Donnelly, J.L.4
Budzik, G.P.5
Pollock, J.S.6
Basha, F.7
Carter, G.W.8
-
23
-
-
0028093424
-
SB 209670, a rationally designed potent nonpeptide endothelin receptor antagonist
-
OHLSTEIN, E.H., NAMBI, P., DOUGLAS, S.A., EDWARDS, R.M., GELLAI, M., LAGO, A., LEBER, J.D., COUSINS, R.D., GAO, A., FRAZEE, J.S., PEISHOFF, C.E., BEAN, J.W., EGGLESTON, D.S., ELSHOURBAGY, N.A., KUMAR, C., LEE, J.A., YUE, T-L., LOUDEN, C., BROOKS, D.P., WEINSTOCK, J., FEUERSTEIN, G., POSTE, G., RUFFOLO, R.R., GLEASON, J.G. & ELLIOTT, J.D. (1994). SB 209670, a rationally designed potent nonpeptide endothelin receptor antagonist. Proc. Natl. Acad. Sci. U.S.A., 91, 8052-8056.
-
(1994)
Proc. Natl. Acad. Sci. U.S.A.
, vol.91
, pp. 8052-8056
-
-
Ohlstein, E.H.1
Nambi, P.2
Douglas, S.A.3
Edwards, R.M.4
Gellai, M.5
Lago, A.6
Leber, J.D.7
Cousins, R.D.8
Gao, A.9
Frazee, J.S.10
Peishoff, C.E.11
Bean, J.W.12
Eggleston, D.S.13
Elshourbagy, N.A.14
Kumar, C.15
Lee, J.A.16
Yue, T.-L.17
Louden, C.18
Brooks, D.P.19
Weinstock, J.20
Feuerstein, G.21
Poste, G.22
Ruffolo, R.R.23
Gleason, J.G.24
Elliott, J.D.25
more..
-
24
-
-
0026766944
-
Histamine N-methyl-transferase controls the contractile response of guinea pig trachea to histamine
-
OHRUI, T., YAMAUCHI, K., SEZIKAWA, K., OHKAWARA, Y., MAEYAMA, K., SASAKI, M., TAKEMURA, M., WADA, H., WATANABE, T., SASAKI, II. & TAKISHIMA, T. (1992). Histamine N-methyl-transferase controls the contractile response of guinea pig trachea to histamine. J. Pharmacol. Exp. Ther., 261, 1268-1272.
-
(1992)
J. Pharmacol. Exp. Ther.
, vol.261
, pp. 1268-1272
-
-
Ohrui, T.1
Yamauchi, K.2
Sezikawa, K.3
Ohkawara, Y.4
Maeyama, K.5
Sasaki, M.6
Takemura, M.7
Wada, H.8
Watanabe, T.9
Sasaki, I.I.10
Takishima, T.11
-
25
-
-
0027517899
-
Aminoguanidine: A drug proposed for prophylaxis in diabetes inhibits catalase and generates hydrogen peroxide in vitro
-
OU, P. & WOLFF, S.P. (1993). Aminoguanidine: a drug proposed for prophylaxis in diabetes inhibits catalase and generates hydrogen peroxide in vitro. Biochem. Pharmacol., 46, 1139-1144.
-
(1993)
Biochem. Pharmacol.
, vol.46
, pp. 1139-1144
-
-
Ou, P.1
Wolff, S.P.2
-
26
-
-
0027500926
-
Effect of dexamethasone on the onset and persistence of vascular hyporeactivity induced by E. coli lipopolysaccharide in rats
-
PAYA, D., GRAY, G.A., FLEMING, I. & STOCLET, J-C. (1993). Effect of dexamethasone on the onset and persistence of vascular hyporeactivity induced by E. coli lipopolysaccharide in rats. Circ. Shock, 41, 103-112.
-
(1993)
Circ. Shock
, vol.41
, pp. 103-112
-
-
Paya, D.1
Gray, G.A.2
Fleming, I.3
Stoclet, J.-C.4
-
27
-
-
0027984808
-
Endothelins: Molecular biology, biochemistry, pharmacology, physiology, and pathophysiology
-
RUBANYI, G.M. & POLOKOFF, M.A. (1994). Endothelins: molecular biology, biochemistry, pharmacology, physiology, and pathophysiology, Pharmacol. Rev., 46, 325-415.
-
(1994)
Pharmacol. Rev.
, vol.46
, pp. 325-415
-
-
Rubanyi, G.M.1
Polokoff, M.A.2
-
28
-
-
0021920139
-
The influence of catabolic reactions on polyamine excretion
-
SEILER, N., BOLKENIUS, F.N. & KNODGEN, B. (1985). The influence of catabolic reactions on polyamine excretion. Biochem. J., 225, 219-226.
-
(1985)
Biochem. J.
, vol.225
, pp. 219-226
-
-
Seiler, N.1
Bolkenius, F.N.2
Knodgen, B.3
-
29
-
-
0028848015
-
Isothioureas: Potent inhibitors of nitric oxide synthases with variable isoform selectivity
-
SOUTHAN, G.J., SZABÓ, C. & THIEMERMANN. C. (1995). Isothioureas: potent inhibitors of nitric oxide synthases with variable isoform selectivity. Br. J. Pharmacol., 114, 510-516.
-
(1995)
Br. J. Pharmacol.
, vol.114
, pp. 510-516
-
-
Southan, G.J.1
Szabó, C.2
Thiemermann, C.3
-
30
-
-
0024334174
-
Endotoxin stimulates endothelin-release in vivo and in vitro as determined by radioimmunoassay
-
SUGIURA, M., INAGAMI, T. & KON, V. ( 1989). Endotoxin stimulates endothelin-release in vivo and in vitro as determined by radioimmunoassay. Biochem. Biophys. Res. Commun., 161, 1220-1227.
-
(1989)
Biochem. Biophys. Res. Commun.
, vol.161
, pp. 1220-1227
-
-
Sugiura, M.1
Inagami, T.2
Kon, V.3
-
31
-
-
0027476883
-
Nitric oxide-mediated hyporeactivity to noradrenaline precedes the induction of nitric oxide synthase in endotoxin shock
-
SZABO, C., MITCHELL, J.A., THIEMERMANN, C. & VANE, J.R (1993). Nitric oxide-mediated hyporeactivity to noradrenaline precedes the induction of nitric oxide synthase in endotoxin shock. Br. J. Pharmacol., 108, 786-792.
-
(1993)
Br. J. Pharmacol.
, vol.108
, pp. 786-792
-
-
Szabo, C.1
Mitchell, J.A.2
Thiemermann, C.3
Vane, J.R.4
-
32
-
-
0026327242
-
Modulation of circulating endothelin levels in hypertension and endotoxaemia in rats
-
VEMULAPALLI, S., CHIU, P.J.S., RIVELLI, M., FOSTER, C.J. & SYBERTZ, E.J. (1991). Modulation of circulating endothelin levels in hypertension and endotoxaemia in rats. J. Cardiovasc. Pharmacol., 18, 895-903.
-
(1991)
J. Cardiovasc. Pharmacol.
, vol.18
, pp. 895-903
-
-
Vemulapalli, S.1
Chiu, P.J.S.2
Rivelli, M.3
Foster, C.J.4
Sybertz, E.J.5
-
33
-
-
0027935254
-
Regional haemodynamic responses to acetylcholine, methoxamine, salbutamol and bradykinin during lipopolysaccharide infusion in conscious rats
-
WALLER, J., GARDINER, S.M. & BENNETT, T. (1994a). Regional haemodynamic responses to acetylcholine, methoxamine, salbutamol and bradykinin during lipopolysaccharide infusion in conscious rats. Br. J. Pharmacol., 112, 1057-1064.
-
(1994)
Br. J. Pharmacol.
, vol.112
, pp. 1057-1064
-
-
Waller, J.1
Gardiner, S.M.2
Bennett, T.3
-
34
-
-
84989416667
-
The effect of aminoguanidine on the regional haemodynamic changes during a continuous low infusion of lipopolysaccharide in conscious rats
-
WALLER, J., GARDINER, S.M. & BENNETT, T. (1994b). The effect of aminoguanidine on the regional haemodynamic changes during a continuous low infusion of lipopolysaccharide in conscious rats. Br. J. Pharmacol., 113, 6P.
-
(1994)
Br. J. Pharmacol.
, vol.113
-
-
Waller, J.1
Gardiner, S.M.2
Bennett, T.3
-
35
-
-
84989457677
-
Aminoguanidine does not diminish lipopolysaccharide-induced vascular hyporesponsiveness to acetylcholine or methoxamine in conscious rats
-
WALLER, J., GARDINER, S.M. & BENNETT, T. (1995). Aminoguanidine does not diminish lipopolysaccharide-induced vascular hyporesponsiveness to acetylcholine or methoxamine in conscious rats. Br. J. Pharmacol., 114, 27P.
-
(1995)
Br. J. Pharmacol.
, vol.114
-
-
Waller, J.1
Gardiner, S.M.2
Bennett, T.3
-
36
-
-
0028911559
-
Aminoguanidine attenuates the delayed circulatory failure and improves survival in rodent models of endotoxic shock
-
WU, C-C., CHEN, S-J., SZABÓ, C., THIEMERMANN, C. & VANE, J.R. (1995a). Aminoguanidine attenuates the delayed circulatory failure and improves survival in rodent models of endotoxic shock. Br. J. Pharmacol., 114, 1666-1672.
-
(1995)
Br. J. Pharmacol.
, vol.114
, pp. 1666-1672
-
-
Wu, C.-C.1
Chen, S.-J.2
Szabó, C.3
Thiemermann, C.4
Vane, J.R.5
-
37
-
-
0028899719
-
Lipocortin 1 mediates the inhibition by dexamethasone of the induction by endotoxin of nitric oxide synthase in the rat
-
WU, C-C., CROXTALL, J.D., PERRETTI, M., BRYANT, C.E., THIEMERMANN, C., FLOWER, R.J. & VANE, J.R. (1995b). Lipocortin 1 mediates the inhibition by dexamethasone of the induction by endotoxin of nitric oxide synthase in the rat. Proc. Natl. Acad. Sci. U.S.A., 92, 3473-3477.
-
(1995)
Proc. Natl. Acad. Sci. U.S.A.
, vol.92
, pp. 3473-3477
-
-
Wu, C.-C.1
Croxtall, J.D.2
Perretti, M.3
Bryant, C.E.4
Thiemermann, C.5
Flower, R.J.6
Vane, J.R.7
|