Solid-phase synthesis of artificial β-sheets

Journal of the American Chemical Society

Volumn 119, Issue 33, 1997, Pages 7665-7669

  Holmes, Darren L ^a   Smith, Eric M ^a   Nowick, James S ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; BETA CHAIN; CHEMICAL STRUCTURE; HYDROGEN BOND; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PROTEIN SYNTHESIS; PURIFICATION;

EID: 0030883636     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja9710971     Document Type: Article

References (18)

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2. (b) Nowick, J. S.; Smith, E. M.; Pairish, M. Chem. Soc. Rev. 1996, 25, 401.
3. (c) Service, R. F. Science 1996, 274, 34.
4. (a) Nowick, J. S.; Smith, E. M.; Noronha, G. J. Org. Chem. 1995, 60, 7386.
5. (b) Nowick, J. S.; Holmes, D. L.; Mackin, G.; Noronha, G.; Shaka, A. J.; Smith, E. M. J. Am. Chem. Soc. 1996, 118, 2764.
6. (c) Nowick, J. S.; Pairish, M.; Lee, I. Q.; Holmes, D. L.; Ziller, J. W. J. Am. Chem. Soc. 1997, 119, 5413.
7. Structural studies of artificial β-sheet 4 will be described in a forthcoming paper. Studies of a closely related artificial β-sheet comprising a triurea template, a β-strand mimic, and two peptide strands are described in ref 1b.
8. Nowick, J. S.; Holmes, D. L.; Noronha, G.; Smith, E. M.; Nguyen, T. M.; Huang, S.-L. J. Org. Chem. 1996, 61, 3929.
9. Stewart, J. M.; Young, J. D. Solid Phase Peptide Synthesis, 2nd ed.; Pierce Chemical Company: Rockford, IL, 1984.
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11. de Paulis, T.; Janowsky, A.; Kessler, R. M.; Clanton, J. A.; Smith, H. E. J. Med. Chem. 1988, 31, 2027.
12. Zervas, L.; Borovas, D.; Gazis, E. J. Am. Chem. Soc. 1963, 85, 3660.
13. Romani, S.; Bovermann, G.; Moroder, L.; Wünsch, E. Synthesis 1985, 512.
14. (a) Wünsch, E.; Spangenberg, R. Chem. Ber. 1972, 105, 740.
15. (b) Lüscher, I. F.; Schneider, C. H. Helv. Chim. Acta 1983, 66, 602.
16. Nowick, J. S.; Powell, N. A.; Nguyen, T. M.; Noronha, G. J. Org. Chem. 1992, 57, 7364.
17. Reference 5, p 91.
18. Nowick, J.; Smith, E. M. Unpublished results.