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Volumn 27, Issue 1, 1999, Pages 53-57

Development of a recombinant interleukin-4-pseudomonas exotoxin for therapy of glioblastoma

Author keywords

Antitumor activity; Cytotoxicity; Glioblastoma; Interleukin 4 receptors; Interleukin 4 Pseudomonas exotoxin; Recombinant chimeric protein; Toxicology

Indexed keywords

CHIMERIC PROTEIN; IMMUNOMODULATING AGENT; INTERLEUKIN 4 RECEPTOR; PSEUDOMONAS EXOTOXIN; RECOMBINANT INTERLEUKIN 4;

EID: 0032979235     PISSN: 01926233     EISSN: None     Source Type: Journal    
DOI: 10.1177/019262339902700111     Document Type: Conference Paper
Times cited : (34)

References (28)
  • 1
    • 0027315711 scopus 로고
    • A wide range of human cancers express IL-4 receptors that can be targeted with chimeric toxin composed of IL-4 and Pseudomonas exotoxin
    • Debinski W, Puri RK, Kreitman RJ, and Pastan I (1993). A wide range of human cancers express IL-4 receptors that can be targeted with chimeric toxin composed of IL-4 and Pseudomonas exotoxin. J. Biol Chem. 268: 14065-14070.
    • (1993) J. Biol Chem. , vol.268 , pp. 14065-14070
    • Debinski, W.1    Puri, R.K.2    Kreitman, R.J.3    Pastan, I.4
  • 3
    • 0032529436 scopus 로고    scopus 로고
    • Complete regression of established glioblastoma tumor xenografts by interleukin-4 toxin therapy
    • Husain SR, Bihari N, Kreitman RJ, Pastan I, and Puri RK (1998). Complete regression of established glioblastoma tumor xenografts by interleukin-4 toxin therapy. Cancer Res. 58: 3649-3653.
    • (1998) Cancer Res. , vol.58 , pp. 3649-3653
    • Husain, S.R.1    Bihari, N.2    Kreitman, R.J.3    Pastan, I.4    Puri, R.K.5
  • 4
    • 0030834337 scopus 로고    scopus 로고
    • Interleukin-4 receptor expression on AIDS-associated kaposi's sarcoma cells and their targeting by a chimeric protein comprised of circularly permuted interleukin-4 and Pseudomonas exotoxin
    • Husain SR, Gill P, Kreitman RJ, Pastan I, and Puri RK (1997). Interleukin-4 receptor expression on AIDS-associated Kaposi's sarcoma cells and their targeting by a chimeric protein comprised of circularly permuted interleukin-4 and Pseudomonas exotoxin. Mol. Med. 3: 327-338.
    • (1997) Mol. Med. , vol.3 , pp. 327-338
    • Husain, S.R.1    Gill, P.2    Kreitman, R.J.3    Pastan, I.4    Puri, R.K.5
  • 6
    • 0027731604 scopus 로고
    • Sharing of interleukin-2 (IL-2) receptor γ chain between receptors for IL-2 and IL-4
    • Kondo M, Takeshita T, Ishi N, Nakamura M, Watanabe S, Arai K. and Sugamura K (1993). Sharing of interleukin-2 (IL-2) receptor γ chain between receptors for IL-2 and IL-4. Science 262: 1874-1877.
    • (1993) Science , vol.262 , pp. 1874-1877
    • Kondo, M.1    Takeshita, T.2    Ishi, N.3    Nakamura, M.4    Watanabe, S.5    Arai, K.6    Sugamura, K.7
  • 7
    • 0028178981 scopus 로고
    • A circularly permutated recombinant interleukin-4 toxin with increased activity
    • Kreitman RJ, Puri RK, and Pastan I (1994). A circularly permutated recombinant interleukin-4 toxin with increased activity. Proc. Natl. Acad Sci. USA 91: 6889-6893.
    • (1994) Proc. Natl. Acad Sci. USA , vol.91 , pp. 6889-6893
    • Kreitman, R.J.1    Puri, R.K.2    Pastan, I.3
  • 8
    • 0029135360 scopus 로고
    • Increased antitumor activity of a circularly permuted IL4-toxin in mice with IL-4 receptor bearing human carcinoma
    • Kreitman RJ, Puri RK, and Pastan I (1995). Increased antitumor activity of a circularly permuted IL4-toxin in mice with IL-4 receptor bearing human carcinoma. Cancer Res. 55: 3357-3363.
    • (1995) Cancer Res. , vol.55 , pp. 3357-3363
    • Kreitman, R.J.1    Puri, R.K.2    Pastan, I.3
  • 9
    • 0029557497 scopus 로고
    • Receptors for interleukin (IL)-4 do not associate with the common γ chain, and IL-4 induces the phosphorylation of JAK2 tyrosine kinase in human colon carcinoma cells
    • Murata T, Noguchi PD, and Puri RK (1995). Receptors for interleukin (IL)-4 do not associate with the common γ chain, and IL-4 induces the phosphorylation of JAK2 tyrosine kinase in human colon carcinoma cells. J. Biol. Chem. 270: 30829-30836.
    • (1995) J. Biol. Chem. , vol.270 , pp. 30829-30836
    • Murata, T.1    Noguchi, P.D.2    Puri, R.K.3
  • 10
    • 0031559793 scopus 로고    scopus 로고
    • Structure of IL-13 receptor: Analysis of subunit composition in cancer and immune cells
    • Murata T, Obiri NI, Debinski W, and Puri RK (1997). Structure of IL-13 receptor: Analysis of subunit composition in cancer and immune cells. Biochem. Biophys. Res. Commun. 238: 90-94.
    • (1997) Biochem. Biophys. Res. Commun. , vol.238 , pp. 90-94
    • Murata, T.1    Obiri, N.I.2    Debinski, W.3    Puri, R.K.4
  • 11
    • 0032009864 scopus 로고    scopus 로고
    • Structure of and signal transduction through interleukin 4 and interleukin 13 receptors
    • Murata T, Obiri NI, and Puri RK (1998). Structure of and signal transduction through interleukin 4 and interleukin 13 receptors. Int. J. Mol. Med. 1: 551-557.
    • (1998) Int. J. Mol. Med. , vol.1 , pp. 551-557
    • Murata, T.1    Obiri, N.I.2    Puri, R.K.3
  • 12
    • 0032525073 scopus 로고    scopus 로고
    • Interleukin-13 receptor α′ but not a chain: A functional component of interleukin-4 receptor
    • Murata T, Taguchi J, and Puri RK (1998). Interleukin-13 receptor α′ but not a chain: A functional component of interleukin-4 receptor. Blood 91: 3884-3891.
    • (1998) Blood , vol.91 , pp. 3884-3891
    • Murata, T.1    Taguchi, J.2    Puri, R.K.3
  • 14
    • 0027469405 scopus 로고
    • Expression of high affinity interleukin-4 receptors on human renal cell carcinoma cells and inhibition of tumor cell growth in vitro by interleukin-4
    • Obiri NI, Hillman G, Haas GP, Sud S, and Puri RK (1993). Expression of high affinity interleukin-4 receptors on human renal cell carcinoma cells and inhibition of tumor cell growth in vitro by interleukin-4. J. Clin. Invest. 91: 88-93.
    • (1993) J. Clin. Invest. , vol.91 , pp. 88-93
    • Obiri, N.I.1    Hillman, G.2    Haas, G.P.3    Sud, S.4    Puri, R.K.5
  • 15
    • 0031568012 scopus 로고    scopus 로고
    • The IL-13 receptor structure differs on various cell types and may share more than one component with IL-4 receptor
    • Obiri NI, Leland P, Murata T, Debinski W, and Puri RK (1997). The IL-13 receptor structure differs on various cell types and may share more than one component with IL-4 receptor. J. Immunol. 158: 756-764.
    • (1997) J. Immunol. , vol.158 , pp. 756-764
    • Obiri, N.I.1    Leland, P.2    Murata, T.3    Debinski, W.4    Puri, R.K.5
  • 16
    • 0028321590 scopus 로고
    • Expression and function of high affinity interleukin-4 receptors on human melanoma, ovarian and breast carcinoma cells
    • Obiri NI, Siegel JP, Varricchio F, and Puri RK (1994). Expression and function of high affinity interleukin-4 receptors on human melanoma, ovarian and breast carcinoma cells. Clin. Exp. Immunol. 95: 148-155.
    • (1994) Clin. Exp. Immunol. , vol.95 , pp. 148-155
    • Obiri, N.I.1    Siegel, J.P.2    Varricchio, F.3    Puri, R.K.4
  • 18
    • 0026321498 scopus 로고
    • Recombinant toxins for cancer treatment
    • Pastan I and FitzGerald D (1991). Recombinant toxins for cancer treatment. Science 254: 1173-1177.
    • (1991) Science , vol.254 , pp. 1173-1177
    • Pastan, I.1    FitzGerald, D.2
  • 19
    • 0025764757 scopus 로고
    • Interleukin-4: A prototypic immunoregulatory lymphokine
    • Paul WE (1990). Interleukin-4: A prototypic immunoregulatory lymphokine. Blood 77: 1859-1870.
    • (1990) Blood , vol.77 , pp. 1859-1870
    • Paul, W.E.1
  • 20
    • 0029433641 scopus 로고
    • Structure and function of interleukin 4 and its receptors
    • R Kurzrock and M Talpaz (eds). Kluwer, Norwell, Massachusetts
    • Puri RK (1995). Structure and function of interleukin 4 and its receptors. In: Cytokines: Interleukins and Their receptors, R Kurzrock and M Talpaz (eds). Kluwer, Norwell, Massachusetts, pp. 143-186.
    • (1995) Cytokines: Interleukins and Their Receptors , pp. 143-186
    • Puri, R.K.1
  • 21
    • 0028353277 scopus 로고
    • Human renal cell carcinoma cells are sensitive to the cytotoxic effect of a chimeric protein comprised of human interleukin-4 and Pseudomonas exotoxin
    • Puri RK, Debinski W, Obiri N, Kreitman R, and Pastan I (1994). Human renal cell carcinoma cells are sensitive to the cytotoxic effect of a chimeric protein comprised of human interleukin-4 and Pseudomonas exotoxin. Cell. Immunol. 154: 369-379.
    • (1994) Cell. Immunol. , vol.154 , pp. 369-379
    • Puri, R.K.1    Debinski, W.2    Obiri, N.3    Kreitman, R.4    Pastan, I.5
  • 22
    • 0029751129 scopus 로고    scopus 로고
    • Preclinical development of a recombinant toxin containing circularly permuted interleukin-4 and truncated Pseudomonas exotoxin for therapy of malignant astrocytoma
    • Puri RK, Hoon DS, Leland P, Snoy P, Rand RW, Pastan I, and Kreitman RJ (1996). Preclinical development of a recombinant toxin containing circularly permuted interleukin-4 and truncated Pseudomonas exotoxin for therapy of malignant astrocytoma. Cancer Res. 56: 5631-5637.
    • (1996) Cancer Res. , vol.56 , pp. 5631-5637
    • Puri, R.K.1    Hoon, D.S.2    Leland, P.3    Snoy, P.4    Rand, R.W.5    Pastan, I.6    Kreitman, R.J.7
  • 23
    • 0028067301 scopus 로고
    • Human neurological cancer cells express interleukin-4 (IL-4) receptors which are targets for the cytotoxic effect of IL-4-Pseudomonas exotoxin chimeric protein
    • Puri RK, Leland P, Kreitman RJ, and Pastan I (1994). Human neurological cancer cells express interleukin-4 (IL-4) receptors which are targets for the cytotoxic effect of IL-4-Pseudomonas exotoxin chimeric protein. Int. J. Cancer 58: 574-581.
    • (1994) Int. J. Cancer , vol.58 , pp. 574-581
    • Puri, R.K.1    Leland, P.2    Kreitman, R.J.3    Pastan, I.4
  • 25
    • 0025821068 scopus 로고
    • Expression of high affinity IL-4 receptors on murine sarcoma cells and receptor mediated cytotoxicity of tumor cells to chimeric protein between IL-4 and Pseudomonas exotoxin
    • Puri RK, Ogata M, Leland P, Feldman GM, FitzGerald D, and Pastan I (1991). Expression of high affinity IL-4 receptors on murine sarcoma cells and receptor mediated cytotoxicity of tumor cells to chimeric protein between IL-4 and Pseudomonas exotoxin. Cancer Res. 51: 3011-3017.
    • (1991) Cancer Res. , vol.51 , pp. 3011-3017
    • Puri, R.K.1    Ogata, M.2    Leland, P.3    Feldman, G.M.4    FitzGerald, D.5    Pastan, I.6
  • 26
    • 0027259503 scopus 로고
    • Interleukin-4 and cancer therapy
    • Puri RK and Siegel JP (1993). Interleukin-4 and cancer therapy. Cancer Invest. 11: 473-486.
    • (1993) Cancer Invest. , vol.11 , pp. 473-486
    • Puri, R.K.1    Siegel, J.P.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.