Analysis of induced sputum after air and ozone exposures in healthy subjects

Environmental Research

Volumn 70, Issue 2, 1995, Pages 77-83

  Fahy, John V ^a,b   Wong, Hofer H ^b   Liu, Jane T ^b   Boushey, Homer A ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0029551324     PISSN: 00139351     EISSN: None     Source Type: Journal    
DOI: 10.1006/enrs.1995.1051     Document Type: Article

References (23)

1. Aris, R. M., Christian, D., Hearne, P. Q., Ken, K., Finkbeiner, W. E., and Balmes, J. (1993). Ozone-induced airway inflammation in human subjects as determined by airway lavage and biopsy. Am. Rev. Respir. Dis. 148, 1363-1372.
2. Claman, D., Boushey, H. A., Liu, J., Wong, H., and Fahy, J. V. (1994). Analysis of induced sputum to examine the effects of prednisone on airway inflammation. J. Allergy Clin. Immunol. 94, 861-869.
3. Devlin, R. B., Mc Donnell, W. F., Mann, R., Becker, S., House, D., Schreinmachers, D., and Koren, H. S. (1991). Exposure of humans to ambient levels of ozone for 6.6 hours causes cellular and biochemical changes in the lung. Am. J. Respir. Cell. Mol. Biol. 4, 72-81.
4. Devlin, R. B., Mc Kinnon, K. P., Noah, T., Becker, S., and Koren, H. S. (1994). Ozone-induced release of cytokines and fibronec-tin by alveolar macrophages and airway epithelial cells. Am. J. Physiol. 266, L612-L619.
5. Fahy, J. V., Liu, J., Wong, H., and Boushey, H. A. (1993a). Cellular and biochemical analysis of induced sputum from asthmatic and healthy subjects. Am. Rev. Respir. Dis. 147, 1126-1131.
6. Fahy, J. V., Steiger, D. J., Liu, J., Basbaum, C. B., Finkbeiner, W. E., and Boushey, H.A. (1993b). Markers of mucus secretion and DNA levels in induced sputum from asthmatic and healthy subjects. Am. Rev. Respir. Dis. 147, 1132-1137.
7. Fahy, J. V., Liu, J., Wong, H., and Boushey, H. A. (1994). Analysis of cellular and biochemical constituents of induced sputum after allergen challenge: A method for studing allergic airway inflammation. J. Allergy Clin. Immunol. 93, 1031-1039.
8. Fahy, J. V., Wong, H. H., Liu, J., and Boushey, H. A. (1995). Comparison of samples collected by sputum induction and bronchoscopy from asthmatic and healthy subjects. Am. J. Respir. Crit. Care Med. 152, 53-58.
9. Hilterman, T. J. N., Stolk, J., Hiemstra, P. S., Fokkens, P. H. B., Rombout, P. J. A., Sont, J. K., Sterk, P. J., and Dijkman, J. H. (1995). Effect of ozone exposure on maximal airway narrowing in non-asthmatic and asthmatic subjects. Clin. Sci. 89, 619-624.
10. Koren, H., Devlin, R. B., Graham, D., Mann, R., Mc Gee, M. P., Horstman, D. H., Kozumbo, W. J., Becker, S., House, D. E., Mc Donnell, W. F., and Bromberg, P. A. (1989). Ozone-induced inflammation in the lower airways of human subjects. Am. Rev. Respir. Dis. 139, 407-415.
11. Kelley, J. (1990). Cytokines of the lung. Am. Rev. Respir. Dis. 141, 765-788.
12. Last, J. A., Jennings, M. D., Schwartz, L. W., and Cross, C. E. (1977). Glycoprotein secretion by tracheal explants cultured from rats exposed to ozone. Am. Rev. Respir. Dis. 116, 695-703.
13. McBride, D. E., Koenig, J. Q., Luchtel, D. L., Williams, P. V., and Henderson, W. R. (1994). Inflammatory effects of ozone in the upper airways of subjects with asthma. Am. J. Respir. Crit. Care Med. 149, 1192-1197.
14. Miller, M. D., and Krangel, M. S. (1992). Biology and biochemistry of the chemokines: A family of chemotactic and inflammatory cytokines. Crit. Rev. Immunol. 12, 17-46.
15. Nauseef, W. M. (1988). Myeloperoxidase deficiency. Hematol. Oncol. Clin. North Am. 2, 135-158.
16. Phipps, R. J., Denas, D. M., Scelzak, M. W., and Wanner, A. (1986). Effects of 0.5 ppm ozone on glycoprotein secretion, ion and water fluxes in sheep trachea. J. Appl. Physiol. 60, 918-927.
17. Pin, I., Freitag, A. P., O’Byme, P. M., Girgis-Gabardo, A., Watson, R. M., Dolovich, J., Denburg, J., and Hargreave, F. E. (1992). Changes in the cellular profile of induced sputum after allergen-induced asthmatic responses. Am. Rev. Respir. Dis. 145, 1265-1269.
18. Pin, I., Gibson, P. G., Kolendowicz, R., Girgis-Gabardo, A., Denburg, J. A., Hargreave, F. E., and Dolovich, J. (1992). Use of induced sputum cell counts to investigate airway inflammation in asthma. Thorax 25-29.
19. Richman-Eisenstat, J. B. Y., Jorens, P. G., Hebert, C., Ueki, I., and Nadel, J. A. (1993). Interleukin-8: An important chemoat-tractant in sputum of patients with chronic inflammatory airway diseases. Am. J. Physiol. (Lung Cell. Mol. Physiol.) 264, L413-L418.
20. Schelegle, E. S., Siefkin, A. D. F., and Mc Donald, R. J. (1991). Time course of ozone-induced neutrophilia in normal humans. Am. Rev. Respir. Dis. 143, 1353-1358.
21. Seltzer, J., Bigby, B. G., Stulbarg, M., Holtzman, M. J., Nadel, J. A., Ueki, I. F., Leikhauf, G. D., Goetzyl, E. J., and Boushey, H. A. (1986). Ozone-induced changes in bronchial reactivity to methacholine and airway inflammation in humans. J. Appl. Physiol. 60, 1321.
22. Ulich, T. R., Yin, S., Guo, K., Yi, E. S., Remick, D., and del Castillo, J. (1991). Intratracheal injection of endotoxin and cytokines. II. Interleukin-6 and transforming growth factor beta inhibit acute inflammation. Am. J. Pathol. 138, 1097-1101.
23. Zgliczynski, J. M. (1980). Characteristics of MPO from neutrophils and other peroxidases from different cells. In “The Reticuloendothelial System, Vol. 2. Biochemistry and Metabolism” (A. J. Sbarra and R. R. Strauss, Eds.), pp. 255-265. Plenum, New York.