Chemical synthesis and characterization of chemokine RANTES and its analogues

Cytokine

Volumn 11, Issue 1, 1999, Pages 8-15

  Boykins, Robert A ^a   Oravecz, Tamas ^a   Unsworth, Edward ^a   Syin, Chiang ^a,b  

^a CENTER FOR BIOLOGICS EVALUATION AND RESEARCH   (United States)

^b CENTER FOR DRUG EVALUATION AND RESEARCH   (United States)

Author keywords

Analogues; Chemical synthesis; Chemokines; RANTES

Indexed keywords

DIPEPTIDYL PEPTIDASE IV; RANTES; RESIN;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; IMMUNOCHEMISTRY; NONHUMAN; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN DEGRADATION; PROTEIN FOLDING; PROTEIN PURIFICATION; PROTEIN SYNTHESIS; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; STRUCTURE ACTIVITY RELATION;

ANIMALIA;

EID: 0032977602     PISSN: 10434666     EISSN: None     Source Type: Journal    
DOI: 10.1006/cyto.1998.0391     Document Type: Article

References (19)

1. Baggiolini M, Dewald B, Moser B (1997) Human chemokines: An update. Annu Rev Immunol 15:675-705.
2. Schall TJ, Jongstra J, Dyer BJ, Jorgensen J, Calyberger C, Davis MM, Krensky AM (1988) A human T cell-specific molecule is a member of a new gene family. J Immunol 141:1018-1025.
3. Heeger P, Wolf G, Meyers C, Sun MJ, O'Farrell SC, Krensky AM, Neilson EG (1992) Isolation and characterization of cDNA from renal tubular epithelium encoding the murine RANTES, a small intercrine from the Scy superfamily. Kidney Int 41:220-225.
4. Nelson PJ, Kim HT, Manning WC, Goralski TJ, Krensky AM (1993) Genomic organization and transcriptional regulation of the RANTES chemokine gene. J Immunol 151:2601-2612.
5. Schall TJ, Bacon K, Toy KJ, Goeddel DV (1990) Selective attraction of monocytes and T lymphocytes of the memory phenotype by cytokine RANTES. Nature 347:669-671.
6. Alkathib G, Combadiere C, Broder CC, Feng Y, Kennedy PE, Murphy PM, Berger EA (1996) CC CKR5: A RANTES, NIP-1a, MIP-1b, receptor as a fusion cofactor for macrophage-tropic HIV-1. Science 272:1955-1958.
7. Gong JH, Uguccion M, Dewald B, Baggiolini M, Clark-Lewis I (1996) RANTES and MCP-3 antagonists bind multiple chemokine receptors. J Biol Chem 271:10521-10527.
8. Arenzana-Seisdedos F, Virelizier JL, Rousset D, Clark-Lewis I, Loetscher P, Moser B, Baggiolini M (1996) HIV blocked by chemokine antagonist. Nature 383:400.
9. Simmons G, Clapham PR, Picard L, Offord RE, Rosenkilde MM, Schwartz TW, Buser R, Wells TNC, Proudfoot, AEI (1997) Potent inhibition of HIV-1 infectivity in macrophages and lymphocytes by a novel CCR5 antagonist. Science 276:276-279.
10. Noso N, Sticherling M, Bartels J, Mallet AI, Christophers E, Schroder JM (1996) Identification of an N-terminally truncated form of the chemokine RANTES and granulocyte-macrophage colony-stimulating factor as major eosinophil attractants released by cytokine-stimulated dermal fibroblasts. J Immunol 156: 1946-1953.
11. Oravecz T, Pall M, Roderiquez G, Gorrell MD, Ditto M, Nguyen NY, Boykins R, Unsworth E, Norcross MA (1997) Regulation of the receptor specificity and function of the chemokine RANTES by dipeptidyl peptidase IV (CD26)-mediated cleavage. J Exp Med 186:1865-1872.
12. Clark-Lewis I, Moser B, Walz A, Baggiolini M, Scott GJ, Aebersold R (1991) Chemical synthesis, purification and characterization of two inflammatory proteins, neutrophil activating peptide 1 (interleukin-8) and neutrophil activation peptide 2. Biochem 30:3128-3135.
13. Proost P, Leuven PV, Wuyts A, Ebberink R, Opdenakker G, Damme JV (1995) Cemical synthesis, purification and folding of the human monocyte chemotactic proteins MCP-2 and MCP-3 into biologically active chemokines. Cytokine 7:97-104.
14. Merrifield RB (1963) Solid phase peptide synthesis: The synthesis of a tetrapeptide. J Am Chem Soc 85:2149-2153.
15. Atherton E, Sheppard RC (1989) Solid-phase Peptide Synthesis. IRL Press, Oxford.
16. Sarin VK, Kent SBH, Tam JP, and Merrifield RB (1981) Quantitative monitoring of solid-phase peptide synthesis by the Ninhydrin reaction. Anal Biochem. 117:147-157.
17. Oravecz T, Pall M, Norcross MA (1996) Beta-chemokine inhibition of monocytotropic HIV-1 infection: Interference with a post-binding fusion step. J Immunol 157:1329-1332.
18. Veber DF, Milkowski JD, Varga SL, Denkewalter RG, Hirschmann R (1972) Acetamidomethyl. A novel thiol protecting group for cysteine. J Am Chem Soc 94:5456-5461.
19. Liu TY, Boykins RA (1989) Hydrolysis of proteins and peptides in a hermetically sealed microcapillary tube: High recovery of labile amino acids. Anal Biochem 182:383-387.