Unexpected increased thiabendazole tolerance in Haemonchus contortus resistant to anthelmintics by modulation of glutathione activity

Parasitology Research

Volumn 85, Issue 8-9, 1999, Pages 713-718

  Kerboeuf, Dominique ^a   Aycardi, Jacques ^a  

^a CEMAGREF   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ANTHELMINTIC AGENT; ANTINEOPLASTIC AGENT; ANTIPROTOZOAL AGENT; BENZIMIDAZOLE DERIVATIVE; BUTHIONINE SULFOXIMINE; GLUTATHIONE; GLUTATHIONE TRANSFERASE; MALEIC ACID DIETHYL ESTER; PATULIN; TIABENDAZOLE;

APOPTOSIS; ARTICLE; CYTOTOXICITY; DRUG RESISTANCE; DRUG SENSITIVITY; HAEMONCHUS CONTORTUS; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; ANTINEMATODAL AGENTS; DRUG RESISTANCE; GLUTATHIONE; HAEMONCHUS; THIABENDAZOLE;

EID: 0032975821     PISSN: 00443255     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004360050620     Document Type: Article

References (43)

1. Asakura T, Takahashi N, Takada K, Inoue T, Ohkwa K (1997) Drug conjugate of doxorubicin with glutathione is a potent reverser of multidrug resistance in rat hepatoma cells. Anticancer Drugs 8: 199-203
2. Asakura T, Ohkawa K, Takahashi N, Takada K, Inoue T, Yokohama S (1997) Glutathione-doxorubicin expresses potent cytotoxicity by suppression of glutathione S-tranferase activity: comparison between doxorubicin-sensitive and -resistant rat hepatoma cells Br J Cancer 76: 1333-1337
3. Bailey HH, Mulcahy RT, Tutsch KD, Arzoomanian RZ, Alberti D, Tombes MB, Wilding G, Pomplun M, Springs DR (1994) Phase I clinical trial of intravenous L-buthionine sulfoximine and melphalan: an attempt at modulation of glutathione. J Clin Oncol 12: 194-205
4. Barrett J (1995) Helminth glutathione transferase. Helminthologia 32: 125-128
5. Barrett J (1997) Helminth detoxification mechanisms. J Helminthol 71: 85-89
6. Beaumont-Schwartz C, Kerboeuf D, Hubert J (1987) Méthodes de mise en evidence de souches de strongles gastro-intestinaux résistantes aux anthelminthiques. Rec Med Vet 163: 683-688
7. Beugnet F, Kerboeuf D, Nicolle JC, Soubieux D (1996) Use of free-living stages to study the effects of thiabendazole, levamisole, pyrantel and ivermectin on the fine structure of Haemonchus contortus and Heligmosomoides polygyrus. Vet Parasitol 63: 83-94
8. Boggs SE, McCormick TS, Lapetina EG (1998) Glutathione levels determine apoptosis in macrophages. Biochem Biophys Res Commun 247: 229-233
9. Brophy PM, Crowley P, Barrett J (1990) Relative distribution of glutathione transferase, glyoxalase I and glyoxalase II in helminths. Int J Parasitol 20: 259-261
10. Burghart RC, Barhomi R, Lewis EH, Bailey EH, Pyle KA, Clement BA, Phillips TD (1992) Patulin-induced toxicity: a vital fluorescence study. Toxicol Appl Pharmacol 112: 235-244
11. Chasseaud LF (1979) The role of glutathione and glutathione-S-transferases in the metabolism of chemical carcinogens and other electrophilic agents. Adv Cancer Res 29: 175-274
12. Chuman Y, Chen ZS, Scto K, Sumizawa T, Furukawa T, Tani A, Haraguchi M, Niwa K, Yamada K, Aikou T, Akiyama S (1998) Reversal of MRP-mediated vincristine resistance in KB cells by buthionine sulfoximine in combination with PAK-104P. Cancer Lett 129: 69-76
13. Cioli D, Pica-Mattoccia L, Archer S (1995) Antischistosmial drugs: past, present and future ? Pharmacol Ther 68: 35-85
14. Cunningham ML, Fairlamb AH (1995) Trypanothione reductase from Leishmania donovani. Purification, characterisation and inhibition by trivalent antimonials. Eur J Biochem 230: 460-468
15. Dubois VL, Platel DFN, Pauly G, Tribouleyduret J (1995) Plasmodium berghei: implication of intracellular glutathione and its related enzyme in chloroquine resistance in vivo. Exp Parasitol 81: 117-124
16. Fairlamb AH, Cerami A (1985) Identification of a novel, thiol-containing co-factor essential for glutathione reductase enzyme activity in trypanosomatids. Mol Biochem Parasitol 14: 187-198
17. Fairlamb AH, Cerami A (1992) Metabolism and functions of trypanothione in the Kinetoplastida. Annu Rev Microbiol 46: 695-729
18. Fairlamb AH, Blackburn P, Ulrich P, Chait B, Cerami A (1985) Trypanothione: a novel bis(glutathionyl)spermidine cofactor for glutathione reductase in trypanosomatids. Science 227: 1485-1487
19. Griffith OW (1981) Depletion of glutathione by inhibition of biosynthesis. Methods Enzymol 77: 59-63
20. Griffith OW, Meister A (1979) Potent and specific inhibition of glutathione synthesis by buthionine sulfoximine (S-n-butyl homocysteine sulfoximine) J Biol Chem 254: 7558-7560
21. Hedley DW (1993) Flow cytometric assays of anticancer drug resistance. Ann NY Acad Sci 677: 341-353
22. Hussein AS, Walter RD (1996) Inhibition of glutathione synthesis of Ascaris suum by buthionine sulfoximine. Parasitol Res 82: 372-374
23. Kawalek JC, Rews RS, Heavner J (1984) Glutathione S-transferase, a possible drug metabolising enzyme in Haemonchus contortus: comparative activity of a cambendazole-resistant and a susceptible strain. Int J Parasitol 14: 173-175
24. Kerboeuf D, Soubieux D, Guilluy R, Brazier JL, Rivière JL (1995) In vivo metabolism of aminopyrine by the larvae of the helminth Heligmosomoides polygyrus. Parasitol Res 81: 302 304
25. Kerboeuf D, Aycardi J, Soubieux D (1996) Flow cytometric analysis of sheep nematode eggs Parasitol Res 82: 358-363
26. Kotze AC (1997) Cytochrome P450 monooxygenase activity in Haemonchus contortus (Nematoda). Int J Parasitol 27: 33-40
27. Lee TK, Li LQ, Ballatori N (1998) Hepatic glutathione and glutathione S-conjugate transport mechanisms. Yale J Biol Med 70: 287-300
28. Martin RJ, Robertson AP, Bjorn H (1997) Target sites of anthelmintics. Parasitology 114: S111-S124
29. Maya JD, Repetto Y, Agosin M, Ojeda JM, Tellez R, Gaule C, Morello A (1997) Effects of Nifurtimox and benznidazole upon glutathione and trypanothione content in epimastigote, trypomastigote and amastigote forms of Trypanosoma cruzi. Mol Biochem Parasitol 86: 101-106
30. Medh RD, Gupta V, Awashi YC (1991) Reversal of melphalan resistance in vivo and by modulation of glutathione metabolism. Biochem Pharmacol 42: 439-441
31. Meister A (1991) Glutathione deficiency produced by inhibition of its synthesis, and its reversal: applications in research and therapy. Pharmacol Ther 51: 155-194
32. Meister A, Anderson M (1983) Glutathione. Annu Rev Biochem 52: 711-760
33. Millis KK, Lesko SA, Gamcsik MP (1997) Formation, intracellular distribution and efflux of glutathione-bimane conjugates in drug-sensitive and drug-resistant MCF cells. Cancer Chemother Pharmacol 40: 101-111
34. Mukhopadhyay R, Dey S, Xu N, Gage D, Lightbody J, Ouelette M, Rosen BP (1996) Trypanothione overproduction and resistance to antimonials and arsenicals in Leishmania tarentolae. Proc Natl Acad Sci USA: 93: 10383-10387
35. Mulder GJ, Ouwerkerk-Mahadevan S (1997) Modulation of glutathione conjugation in vivo: how to decrease glutathione conjugation in vivo or in intact cellular systems in vitro. Chem-Biol Interact 105: 17-34
36. Nakanishi Y, Matsuki H, Takayama K, Yalsunami J, Kawasaki M, Abe M, Hara N (1997) Glutathione derivatives enhance adriamycin cytotoxicity in a human lung adenocarcinoma cell line. Anticancer Res 17: 2129-2134
37. Olas B. Wachowicz B (1998) Modulation of cisplatin toxicity in blood platelets by glutathione depletion. Anticancer Drugs 9: 473-478
38. Perego P, Romanelli S, Carenini N, Magnani I, Leone R, Bonctti A, Paolicchi A, Zunino F (1998) Ovarian cancer cisplatin-resistant cell lines: multiple changes including collateral sensitivity to Taxol. Annals Oncol 9: 423-430
39. Plummer JL, Smith BR, Sies H, Bend JR (1981) Chemical depletion of glutathione in vivo. Methods Enzymol 77. 50-59
40. Srivastava RK, Srivastava AR, Cho-Chung YS (1996) Multidrug resistance in cancer (review). Int J Oncol 9: 879-884
41. Sumizawa T, Chen ZS, Chuman Y, Seto K, Furukawa T, Haraguchi M, Tani A, Akiyama S (1997) Reversal of multidrug resistance-associated protein-mediated drug resistance by the pyridine analog PAK-104P. Mol Pharmacol 51: 399-405
42. Webb WW, Elfarra AA, Webster KD, Thom RE, Anders MW (1987) Role for an episulfonium ion in S-(2-chloroethyl)-D,L-cysteine-induced cytotoxicity and its reaction with glutathione. Biochemistry 26: 3017-3023
43. Xu BH, Singh SV (1992) Effect of buthionine sulfoximine and ethacrynic acid on cytotoxic activity of mitomycin C analogs BMY 25282 and BMY 25067. Cancer Res 52: 6666-6670