Management of inherited outer retinal dystrophies: Present and future

British Journal of Ophthalmology

Volumn 83, Issue 1, 1999, Pages 120-122

  Chong, N H Victor ^a   Bird, Alan C ^a  

^a MOORFIELDS EYE HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

APOPTOSIS; CELL TRANSPLANTATION; GENE THERAPY; HUMAN; PRIORITY JOURNAL; RETINA DYSTROPHY; SHORT SURVEY;

EID: 0032971670     PISSN: 00071161     EISSN: None     Source Type: Journal    
DOI: 10.1136/bjo.83.1.120     Document Type: Short Survey

References (46)

1. Bird AC. Retinal photoreceptor dystrophies. Am J Ophthalmol 1995; 119:543-62.
2. Bunker CH, Berson EL, Bromley WC, et al. Prevalence of retinitis pigmentosa in Maine. Am J Ophthalmol 1984;97:357-65.
3. Jay M. On the heredity of retinitis pigmentosa. Br J Ophthalmol 1982;66:405-16.
4. Goldberg AF, Molday RS. Defective subunit assembly underlies a digenic form of retinitis pigmentosa linked to mutations in peripherin/rds and rom-1. Proc Natl Acad Sci USA 1996;93:13726-30.
5. Kajiwara K, Berson EL, Dryja TP. Digenic retinitis pigmentosa due to mutations at the unlinked peripherin/RDS and ROM1 loci. Science 1994;264:1604-8.
6. Illingworth DR, Connor WE, Miller RG. α-Betalipoproteinemia: report of two cases and review of therapy. Arch Neurol 1980;37:659-62.
7. Gouras P, Carr RE, Gunkel RD. Retinitis pigmentosa in α-beta-lipoproteinemia: effects of vitamin A. Invest Ophthalmol 1971;10:784-93.
8. Hansen E, Bachen NI, Flage T. Refsum's disease. Eye manifestations in a patient treated with low phytol low phytanic acid diet. Acta Ophthalmol 1979;57:899-913.
9. Newsome DA, Stark-WJ J, Maumenee IH. Cataract extraction and intraocular lens implantation in patients with retinitis pigmentosa or Usher's syndrome. Arch Ophthalmol 1986;104:852-4.
10. Cox SN, Hay E, Bird AC. Treatment of chronic macular oedema with acetazolamide. Arch Ophthalmol 1988;106:1190-5.
11. Berson EL, Rosner B, Sandberg MA, et al. A randomized trial of vitamin A and vitamin E supplementation for retinitis pigmentosa. Arch Ophthalmol 1993;111:761-72.
12. Massof RW, Finkelstein D. Supplemental vitamin A retards loss of ERG amplitude in retinitis pigmentosa. Arch Ophthalmol 1993;111:751-4.
13. Gal A, Apfelstedt Sylla E, Janecke AR, et al. Rhodopsin mutations in inherited retinal dystrophies and dysfunctions. Prog Ret Eye Res 1997;16:51-79.
14. Mullen RJ, La Vail MM. Inherited retinal dystrophy: primary defect in pigment epithelium determined with experimental rat chimeras. Science 1976; 192:799-901.
15. Wyllie AH, Kerr JFR, Currie AR, Cell death: the significance of apoptosis. Int Rev Cytol 1980;68:251-306.
16. Raff MC, Barres BA, Burne JF, et al. Programmed cell death and the control of cell survival. Philos Trans R Soc Lond B Biol Sci 1994;345:265-8.
17. Faktorovich EG, Steinberg RH, Yasumura D, et al. Photoreceptor degeneration in inherited retinal dystrophy delayed by basic fibroblast growth factor. Narwre 1990;347:83-6.
18. Borhani H, Peyman GA, Rahimy MH, et al. Vitreoretinal toxicity of basic fibroblast growth factor. Int Ophthalmol 1993;17:195-9.
19. Thoenen H. The changing scene of neurotrophic factors. Trends Neurosci 1991;14:165-70.
20. Richardson PM. Ciliary neurotrophic factor: a review. Pharmacol Ther 1994; 63:187-98.
21. Unoki K, LaVail MM. Protection of the rat retina from ischemic injury by brain-derived neurotrophic factor, ciliary neurotrophic factor, and basic fibroblast growth factor. Invest Ophthalmol Vis Sci 1994;35:907-15.
22. LaVail MM, Unoki K, Yasumura D, et al. Multiple growth factors, cytokines, and neurotrophins rescue photoreceptors from the damaging effects of constant light. Proc Natl Acad Sci USA 1992;89:11249-53.
23. LaVail MM, Yasumura D, M.atthes MT, et al. Protection of mouse photoreceptors by survival factors in retinal degenerations. Invest Ophthalmol Vis Sci 1998;39:592-602.
24. Fisher SK, Guerin CJ, Linberg KA, et al. BDNF promotes outer segment regeneration in experimentally detached retina. Invest Ophihalmol Vis Sci (Suppl) 1995;36:963.
25. Chong NHV, Alexander RA, Waters L, et al. CNTF analogue, but not BDNF, delays photoreceptor cell death in retinal degeneration. Invest Ophthalmol Vis Sci (Suppl) 1998;39:2689
26. Maysinger D, Krieglstein K, FilipovicGrcic J, et al. Microencapsulated ciliary neurotrophic factor: physical properties and biological activities. Exp Neurol 1996;138:177-88.
27. Travis GH, Groshan KR, Lloyd M, et al. Complete rescue of photoreceptor dysplasia and degeneration in transgenic retinal degeneration slow (rds) mice. Neuron 1992;9:113-9.
28. Pepose JS, Leib DA. Herpes simplex viral vectors for therapeutic gene delivery to ocular tissues. Recent breakthroughs in the molecular genetics of ocular diseases. Invest Ophthalmol Vis Sci 1994;35:2662-6.
29. Ali RR, Reichel MB, Hunt DM, et al. Gene therapy for inherited retinal degeneration, Br J Ophihalmol 1997;81:795-801.
30. Bennett J, Tanabe T, Sun D, et al. Photoreceptor cell rescue in retinal degeneration (rd) mice by in vivo gene therapy. Nature Med 1996;2:649-54.
31. Dreunser KA, Timmers AM, Hauswirth WW, et al. Ribozyme-targeted destruction of RNA associated with autosomal-dominant retinitis pigmentosa. Invest Ophthalmol Vis Sci 1998;39:681-9.
32. Lewin AS, Hauswirth WW, Drenser K, et al. Ribozyme rescue of photoreceptor cells in a transgenic rat model of autosomal dominant retinitis pigmentosa. Invest Ophthalmol Vis Sci (Suppl) 1998;39:5150.
33. Cayouette M, Gravel C. Adenovirus-mediated gene transfer of ciliary neurotrophic factor can prevent photoreceptor degeneration in the retinal degeneration (rd) mouse. Hum Gene Ther 1997;8:423-30.
34. Aramant RB, Seiler MJ, Turner JE. Donor age influences on the success of retinal transplants to adult rat retina. Invest Ophthalmol Vis Sci 1988; 29:498-503.
35. Gouras P, Du J, Gelanze M, et al. Survival and synapse formation of transplanted rat rods. J Neural Transplant Plast 1991;2:91-100.
36. Gouras P, Du J, Gelanze M, et al. Transplantation of photoreceptors labelled with tritiated thymidine into RCS rats. Invest Ophthalmol Vis Sci 1991;32:1704-7.
37. Mohand-Said S, Hicks D, Simonutti M, et al. Photoreceptor transplants increase host cone survival in the retinal degeneration (rd) mouse. Ophthalmic Res 1997;29:290-7.
38. del Cerro M, Das TP, Lazar ES, et al. Neural retinal transplantation into twelve RP patients. Invest Ophthalmol Vis Sci (Suppl) 1997;38:1204.
39. Kaplan HJ, Tezel TH, Berger AS, et al. Human photoreceptor transplantation in retinitis pigmentosa. A safety study. Arch Ophthalmol 1997;115:1168-72
40. Sheedlo HJ, Li LX, Turner JE. Functional and structural characteristics of photoreceptor cells rescued in RPE-cell grafted retinas of RCS dystrophic rats. Exp Eye Res 1989;48:841-54.
41. Sheedlo HJ, Li LX, Turner JE. Photoreceptor cell rescue in the RCS rat by RPE transplantation: a therapeutic approach in a model of inherited retinal dystrophy. Prog Clin Bio Res 1989;314:645-58.
42. Whiteley SJ, Litchfield TM, Coffey PJ, et al. Improvement of the pupillary light reflex of Royal College of Surgeons rats following RPE cell grafts. Exp Neurol 1996;140:100-4.
43. Yamamoto S, Du J, Gouras P, et al. Retinal pigment epithelial transplants and retinal function in RCS rats. Invest Ophthalmol Vis Sci 1993;34:3068-75.
44. Algvere PV, Berglin L, Gouras P, et al. Transplantation of RPE in age-related macular degeneration: observations in disciform lesions and dry RPE atrophy. Graefes Arch Clin Exp Ophthalmol 1997;235:149-58.
45. Humayun MS, Propst R, de Juan E Jr, et al. Bipolar surface electrical stimulation of the vertebrate retina. Arch Ophthalmol 1994;112:110-6.
46. Humayun MS, de Juan E Jr, Dagnelie G, et al. Artificial vision. Invest Ophthalmol Vis Sci (Suppl) 1996;37:2055.