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Volumn 371, Issue 1, 1999, Pages 51-58

Glucose-dependent insulinotropic effects of JTT-608, a novel antidiabetic compound

Author keywords

Insulin secretion; JTT 608; MIN6 cell; Pancreas, perfused; Streptozotocin induced diabetes; Sulphonylurea receptor

Indexed keywords

4 (4 METHYLCYCLOHEXYL) 4 OXOBUTYRIC ACID; ANTIDIABETIC AGENT; GLIBENCLAMIDE; GLUCOSE; SULFONYLUREA; SULFONYLUREA RECEPTOR; TOLBUTAMIDE; UNCLASSIFIED DRUG;

EID: 0032966289     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(99)00141-7     Document Type: Article
Times cited : (3)

References (28)
  • 1
    • 0028927388 scopus 로고
    • A new hypoglycemic agent, A-4166, inhibits ATP-sensitive potassium channels in rat pancreatic β-cells
    • Akiyoshi M., Kakei M., Nakazaki M., Tanaka H. A new hypoglycemic agent, A-4166, inhibits ATP-sensitive potassium channels in rat pancreatic β-cells. Am. J. Physiol. 268:1995;E185-E193.
    • (1995) Am. J. Physiol. , vol.268
    • Akiyoshi, M.1    Kakei, M.2    Nakazaki, M.3    Tanaka, H.4
  • 2
    • 0021741559 scopus 로고
    • Glucose induced closure of single potassium channels in isolated rat pancreatic β-cells
    • Ashcroft F.M., Harrison D.E., Ashcroft S.J.H. Glucose induced closure of single potassium channels in isolated rat pancreatic β-cells. Nature. 312:1984;446-448.
    • (1984) Nature , vol.312 , pp. 446-448
    • Ashcroft, F.M.1    Harrison, D.E.2    Ashcroft, S.J.H.3
  • 3
    • 0020578096 scopus 로고
    • Glibenclamide-associated hypoglycaemia: A report on 57 cases
    • Asplund K., Wiholm B.-E., Lithner F. Glibenclamide-associated hypoglycaemia: a report on 57 cases. Diabetologia. 24:1983;412-417.
    • (1983) Diabetologia , vol.24 , pp. 412-417
    • Asplund, K.1    Wiholm, B.-E.2    Lithner, F.3
  • 4
    • 0030793208 scopus 로고    scopus 로고
    • The postprandial state: Mechanisms of glucose intolerance
    • Dinneen S.F. The postprandial state: mechanisms of glucose intolerance. Diabetic Med. 14:1997;S19-S24.
    • (1997) Diabetic Med. , vol.14
    • Dinneen, S.F.1
  • 6
    • 0023935536 scopus 로고
    • Sulphonylureas and hypoglycemia
    • Ferner R.E., Neil H.A.W. Sulphonylureas and hypoglycemia. Br. Med. J. 296:1988;949-950.
    • (1988) Br. Med. J. , vol.296 , pp. 949-950
    • Ferner, R.E.1    Neil, H.A.W.2
  • 7
    • 0030576668 scopus 로고    scopus 로고
    • Studies on the N-[(trans-4-isopropylcyclohexyl)-calbonyl]-D-phenylalanine (A-4166) receptor in HIT T-15 cells
    • Fujita T., Seto Y., Kondo N., Kato R. Studies on the N-[(trans-4-isopropylcyclohexyl)-calbonyl]-D-phenylalanine (A-4166) receptor in HIT T-15 cells. Biochem. Pharmacol. 52:1996;407-411.
    • (1996) Biochem. Pharmacol. , vol.52 , pp. 407-411
    • Fujita, T.1    Seto, Y.2    Kondo, N.3    Kato, R.4
  • 9
    • 0020623001 scopus 로고
    • Glucose insensitivity and amino-acid hypersensitivity of insulin release in rats with non-insulin-dependent diabetes: A study with the perfused pancreas
    • Giroix M.H., Portha B., Kergoat M., Bailbe D., Picon L. Glucose insensitivity and amino-acid hypersensitivity of insulin release in rats with non-insulin-dependent diabetes: a study with the perfused pancreas. Diabetes. 32:1983;445-451.
    • (1983) Diabetes , vol.32 , pp. 445-451
    • Giroix, M.H.1    Portha, B.2    Kergoat, M.3    Bailbe, D.4    Picon, L.5
  • 10
    • 0016412039 scopus 로고
    • The in vitro perfused pancreas
    • Grodsky G.M., Fanska R.E. The in vitro perfused pancreas. Meth. Enzymol. 39:1975;364-372.
    • (1975) Meth. Enzymol. , vol.39 , pp. 364-372
    • Grodsky, G.M.1    Fanska, R.E.2
  • 11
    • 0022544897 scopus 로고
    • Secondary failure to treatment with oral antidiabetic agents in non-insulin dependent diabetes
    • Groop L.C., Pelkonen R., Koskimies S., Bottazzo G.F., Doniach D. Secondary failure to treatment with oral antidiabetic agents in non-insulin dependent diabetes. Diabetes Care. 9:1986;129-133.
    • (1986) Diabetes Care , vol.9 , pp. 129-133
    • Groop, L.C.1    Pelkonen, R.2    Koskimies, S.3    Bottazzo, G.F.4    Doniach, D.5
  • 12
    • 0024364975 scopus 로고
    • Characteristics of non-insulin dependent diabetic patients with secondary failure to oral antidiabetic therapy
    • Groop L.C., Schalin C., Kallunki A.F., Widen E., Ekstrand A., Eriksson J. Characteristics of non-insulin dependent diabetic patients with secondary failure to oral antidiabetic therapy. Am. J. Med. 87:1989;183-190.
    • (1989) Am. J. Med. , vol.87 , pp. 183-190
    • Groop, L.C.1    Schalin, C.2    Kallunki, A.F.3    Widen, E.4    Ekstrand, A.5    Eriksson, J.6
  • 14
    • 0031038234 scopus 로고    scopus 로고
    • Hypoglycemic and insulinotropic effects of a novel oral antidiabetic agent, (-)-N-(trans-4-isopropylcyclohexane-carbonyl)-D-phenylalanine (A-4166)
    • Ikenoue T., Akiyoshi M., Fujitani S., Okazaki K., Kondo N., Maki T. Hypoglycemic and insulinotropic effects of a novel oral antidiabetic agent, (-)-N-(trans-4-isopropylcyclohexane-carbonyl)-D-phenylalanine (A-4166). Br. J. Pharmacol. 120:1997;137-145.
    • (1997) Br. J. Pharmacol. , vol.120 , pp. 137-145
    • Ikenoue, T.1    Akiyoshi, M.2    Fujitani, S.3    Okazaki, K.4    Kondo, N.5    Maki, T.6
  • 16
    • 0027360242 scopus 로고
    • Pancreatic beta-cell line MIN6 exhibits characteristics of glucose metabolism and glucose-stimulated insulin secretion similar to those of normal islets
    • Ishihara H., Asano T., Tsukuda K., Katagiri H., Inukai K., Anai M., Kikuchi M., Yazaki Y., Miyazaki J.-I., Oka Y. Pancreatic beta-cell line MIN6 exhibits characteristics of glucose metabolism and glucose-stimulated insulin secretion similar to those of normal islets. Diabetologia. 36:1993;1139-1145.
    • (1993) Diabetologia , vol.36 , pp. 1139-1145
    • Ishihara, H.1    Asano, T.2    Tsukuda, K.3    Katagiri, H.4    Inukai, K.5    Anai, M.6    Kikuchi, M.7    Yazaki, Y.8    Miyazaki, J.-I.9    Oka, Y.10
  • 17
    • 0024422762 scopus 로고
    • Effect of loss of first-phase insulin secretion on hepatic glucose production and tissue glucose disposal in humans
    • Luzi L., DeFronzo R.A. Effect of loss of first-phase insulin secretion on hepatic glucose production and tissue glucose disposal in humans. Am. J. Physiol. 257:1989;E241-E246.
    • (1989) Am. J. Physiol. , vol.257
    • Luzi, L.1    Defronzo, R.A.2
  • 18
    • 0025281303 scopus 로고
    • Establishment of a pancreatic β cell line that retains glucose-inducible insulin secretion: Special reference to expression of glucose transporter isoforms
    • Miyazaki J.-I., Araki K., Yamato E., Ikegami H., Asano T., Shibasaki Y., Oka Y., Yamamura K. Establishment of a pancreatic β cell line that retains glucose-inducible insulin secretion: special reference to expression of glucose transporter isoforms. Endocrinology. 127:1990;126-132.
    • (1990) Endocrinology , vol.127 , pp. 126-132
    • Miyazaki, J.-I.1    Araki, K.2    Yamato, E.3    Ikegami, H.4    Asano, T.5    Shibasaki, Y.6    Oka, Y.7    Yamamura, K.8
  • 20
    • 0033042904 scopus 로고    scopus 로고
    • JTT-608 controls blood glucose by enhancement of glucose-stimulated insulin secretion in normal and diabetes mellitus rats
    • Ohta T., Furukawa N., Yonemori F., Wakitani K. JTT-608 controls blood glucose by enhancement of glucose-stimulated insulin secretion in normal and diabetes mellitus rats. Eur. J. Pharmacol. 367:1999;91-99.
    • (1999) Eur. J. Pharmacol. , vol.367 , pp. 91-99
    • Ohta, T.1    Furukawa, N.2    Yonemori, F.3    Wakitani, K.4
  • 21
    • 0016270910 scopus 로고
    • Diabetgenic effect of streptozotocin in the rat during the perinatal period
    • Portha B., Levacher C., Picon L., Rosselin G. Diabetgenic effect of streptozotocin in the rat during the perinatal period. Diabetes. 23:1974;889-895.
    • (1974) Diabetes , vol.23 , pp. 889-895
    • Portha, B.1    Levacher, C.2    Picon, L.3    Rosselin, G.4
  • 22
    • 0023525741 scopus 로고
    • 2+, cAMP, and phospholipid-derived messengers in coupling mechanisms of insulin secretion
    • 2+, cAMP, and phospholipid-derived messengers in coupling mechanisms of insulin secretion. Physiol. Rev. 67:1987;1185-1248.
    • (1987) Physiol. Rev. , vol.67 , pp. 1185-1248
    • Prentki, M.1    Matschinsky, F.M.2
  • 24
    • 0024436438 scopus 로고
    • Glyburide enhances the responsiveness of the β-cell to glucose but does not correct the abnormal patterns of insulin secretion in non insulin-dependent diabetes mellitus
    • Shapiro E.T., Cauter E.V., Tillil H., Given B.D., Hirsh L., Beebe C., Rubenstein A.H., Polonsky K.S. Glyburide enhances the responsiveness of the β-cell to glucose but does not correct the abnormal patterns of insulin secretion in non insulin-dependent diabetes mellitus. J. Clin. Endocrinol. Metab. 69:1989;571-576.
    • (1989) J. Clin. Endocrinol. Metab. , vol.69 , pp. 571-576
    • Shapiro, E.T.1    Cauter, E.V.2    Tillil, H.3    Given, B.D.4    Hirsh, L.5    Beebe, C.6    Rubenstein, A.H.7    Polonsky, K.S.8
  • 27
    • 0019510244 scopus 로고
    • Islet secretion in a new experimental model for non-insulin-dependent diabetes
    • Weir J.C., Clore E.T., Zmachinski C.J., Bornner-Weir S. Islet secretion in a new experimental model for non-insulin-dependent diabetes. Diabetes. 30:1981;590-595.
    • (1981) Diabetes , vol.30 , pp. 590-595
    • Weir, J.C.1    Clore, E.T.2    Zmachinski, C.J.3    Bornner-Weir, S.4
  • 28
    • 0018760738 scopus 로고
    • Starvation diabetes in the rat: Onset, recovery, and specificity of reduced responsiveness of pancreatic β-cells
    • Zawalich W.S., Dye E.S., Pagliara A.S., Rognstad R., Matshinsky F.M. Starvation diabetes in the rat: onset, recovery, and specificity of reduced responsiveness of pancreatic β-cells. Endocrinology. 104:1979;1344-1351.
    • (1979) Endocrinology , vol.104 , pp. 1344-1351
    • Zawalich, W.S.1    Dye, E.S.2    Pagliara, A.S.3    Rognstad, R.4    Matshinsky, F.M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.