Effect of methacholine challenge on cellular composition of sputum induction

Thorax

Volumn 54, Issue 1, 1999, Pages 37-39

  Spanevello, A ^a   Vignola, A M ^b   Bonanno, A ^b   Confalonieri, M ^d   Crimi, E ^c   Brusasco, V ^c  

^a IRCCS   (Italy)

^b CNR   (Italy)

^c UNIVERSITY OF GENOA   (Italy)

^d Fondazion Salvatore Maugeri ^*

Author keywords

Asthma; Induced sputum; Methacholine challenge

Indexed keywords

ALBUMIN; EOSINOPHIL CATIONIC PROTEIN; METHACHOLINE;

ADULT; ARTICLE; ASTHMA; CELL COUNT; CLINICAL ARTICLE; EOSINOPHIL; EPITHELIUM CELL; FEMALE; HUMAN; LUNG FUNCTION; LYMPHOCYTE; MACROPHAGE; MALE; NEUTROPHIL; PRIORITY JOURNAL; PROVOCATION TEST; SPUTUM ANALYSIS; TIME;

EID: 0032965068     PISSN: 00406376     EISSN: None     Source Type: Journal    
DOI: 10.1136/thx.54.1.37     Document Type: Article

References (13)

1. National Asthma Education Program Expert Panel Report. Overview of approaches to asthma therapy. In: Guidelines for the diagnosis and management of asthma. NIH Publication No. 91-3042. Bethesda, MD: Department of Health and Human Services.
2. Hargreave FE, Ryan G, Thomson NC. Bronchial responsiveness to histamine or methacholine in asthma: measurement and clinical significance. J Allergy Clin Immunol 1981;68:347-55.
3. Pin I, Gibson PG, Kolendovicz R, et al. Use of induced sputum cell counts to investigate airway inflammation in asthma. Thorax 1992;47:25-9.
4. Fahy JV, Liu J, Wong H, et al. Cellular and biochemical analysis of induced sputum from asthmatic and from healthy subjects. Am Rev Respir Dis 1993;147:1126-31.
5. Spanevello A, Migliori GB, Sharara AM, et al. Induced sputum to assess airway inflammation: a study of reproducibility. Clin Exp Allergy 1997;27:1138-44.
6. In't Veen JCCM, De Gouw HWFM, Smits HH, et al. Repeatability of cellular and soluble markers of inflammation in induced sputum from patients with asthma. Eur Respir J 1996;9:2441-7.
7. Pizzichini E, Pizzichini MMM, Efthimiadis A, et al. Indices of airway inflammation in induced sputum: reproducibility and validity of cell fluid-phase measurements. Am J Respir Crit Care Med 1996;154:308-17.
8. Crimi E, Spanevello A, Neri M, et al. Dissociation between airway inflammation and airway hyperresponsiveness in allergic asthma. Am J Respir Crit Care Med 1998;157:4-9.
9. Wong HH, Fahy JV. Safety of one method of sputum induction in asthmatic subjects. Am J Respir Crit Care Med 1997; 156:299-303.
10. Quanjer PH, ed. Report of Working Party of European Community for Coal and Steel. Standardization of lung function tests. Bull Eur Physiopathol Respir 1983;19(Suppl 5):7-87.
11. Lam S, Al-Majed S, Chan H, et al. Differences in mediator release between allergic rhinitis and asthma. J Allergy Clin Immunol 1991;87:842-9.
12. Beasley R, Roche WR, Roberts JA, et al. Cellular events in the bronchi in mild asthma and after bronchial provocation. Am Rev Respir Dis 1989;139:806-17.
13. Soderberg M, Lundgren R, Bjermer L, et al. Inhaled methacholine does not influence the cellular composition of bronchoalveolar lavage fluid. Allergy 1993;48:173-6.