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Volumn 8, Issue 1, 1999, Pages 55-59

Intracellular localization and activation of endothelial nitric oxide synthase

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM; NITRIC OXIDE SYNTHASE; PROTEIN KINASE (CALCIUM,CALMODULIN);

EID: 0032964654     PISSN: 10624821     EISSN: None     Source Type: Journal    
DOI: 10.1097/00041552-199901000-00010     Document Type: Review
Times cited : (16)

References (23)
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    • Dynamic activation of endothelial nitric oxide synthase by Hsp90
    • These authors document the agonist-and shear stress-induced formation of a heterocomplex between eNOS and Hsp90 in endothelial cells; they also present evidence for an involvement of Hsp90 in regulating the NO-dependent agonist-induced relaxation of isolated rat aorta using geldanamycin, a potentially specific inhibitor of the ATP-binding site of Hsp90
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    • 2+-dependent regulation of the subcellular distribution of eNOS in endothelial cells. These results confirm 'the eNOS-caveolin regulatory cycle paradigm' by establishing that the eNOS targeting to caveolae is labile and subject to receptor-regulated reversible translocation to perinuclear structures in the cell cytosol
    • 2+-dependent regulation of the subcellular distribution of eNOS in endothelial cells. These results confirm 'the eNOS-caveolin regulatory cycle paradigm' by establishing that the eNOS targeting to caveolae is labile and subject to receptor-regulated reversible translocation to perinuclear structures in the cell cytosol.
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* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.