An allele of RFA1 suppresses RAD52-dependent double-strand break repair in Saccharomyces cerevisae

Genetics

Volumn 151, Issue 2, 1999, Pages 447-451

  Smith, Julianne ^a,b   Rothstein, Rodney ^a  

^a Columbia Univ Coll Phys Surgs ^*  (United States)

^b INSTITUT CURIE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

DNA BINDING PROTEIN; DOUBLE STRANDED DNA;

ALLELE; ARTICLE; DNA REPAIR; DNA STRAND BREAKAGE; GENE DELETION; GENE MUTATION; GENETIC RECOMBINATION; NONHUMAN; PRIORITY JOURNAL; SACCHAROMYCES CEREVISIAE;

DNA REPAIR; DNA, FUNGAL; DNA-BINDING PROTEINS; GENE EXPRESSION REGULATION, FUNGAL; GENES, FUNGAL; MUTATION; RAD52 DNA REPAIR AND RECOMBINATION PROTEIN; RECOMBINATION, GENETIC; REPLICATION PROTEIN A; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS;

SACCHAROMYCES; SACCHAROMYCES CEREVISIAE;

EID: 0032963978     PISSN: 00166731     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (71)

1. BARDWELL, L., A. J. COOPER and E. C. FRIEDBERG, 1992 Stable and specific association between the yeast recombination and DNA repair proteins RAD1 and RAD10 in vitro. Mol. Cell. Biol. 12: 3041-3019.
2. BAUDIN, A., O. OZIER-KALOGEROPOULOS, A. DENOUEL, F. LACROUTE and C. CULLIN, 1993 A simple and efficient method for direct gene deletion in Saccharomyces cerevisiae. Nucleic Acids Res. 21: 3329-3330.
3. BENSON, F. E., P. BAUMANN and S. C. WEST, 1998 Synergistic actions of Rad51 and Rad52 in recombination and DNA repair. Nature 391: 401-401.
4. BOEKE, J. D., F. LACROUTE AND G. R. FINK, 1984 A positive selection for mutants lacking orotidine-5′-phosphate decarboxylase activity in yeast: 5-fluoro-orotic acid resistance. Mol. Gen. Genet. 197: 342-346.
5. BOLLAG, R. J., and R. M. LISKAY, 1991 Direct-repeat analysis of chromatid interactions during intrachromosomal recombination in mouse cells. Mol. Cell. Biol. 11: 4839-4845.
6. BRILL, S. J., and B. STILLMAN, 1991 Replication factor-A from Saccharomyces cerevisiae is encoded by three essential genes coordinately expressed at S phase. Genes Dev. 5: 1589-1600.
7. CASKEY, C. T., A. PIZZUTI, Y. H. FU, R. G. FENWICK, JR. and D. L. NELSON, 1992 Triple repeat mutations in human disease. Science 256: 784-789.
8. CHRISTIANSEN, C., and R. L. BALDWIN, 1977 Catalysis of DNA reassociation by the Escherichia coli DNA binding protein: a polyamine-dependent reaction. J. Mol. Biol. 115: 441-454.
9. D'ANDREA, A., and M. GROMPE, 1997 Molecular biology of Fanconi anemia: implications for diagnosis and therapy. Blood 90: 1725-1736.
10. EDELMAN, G. M., and J. A. GALLY, 1970 Arrangement and Evolution of Eukaryotic Genes. Rockefeller University Press, New York.
11. FAN, H. Y., K. K. CHENG and H. L. KLEIN, 1996 Mutations in the RNA polymerase II transcription machinery suppress the hyperrecombination mutant hpr/delta of Saccharomyces cerevisiae. Genetics 142: 749-759.
12. FEINBERG, A. P., and B. VOGELSTEIN, 1983 A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity. Anal. Biochem. 132: 6-13.
13. FISHMAN-LOBELL, J., and J. E. HABER, 1992 Removal of nonhomologous DNA ends in double-strand break recombination: the role of the yeast ultraviolet repair gene RAD1. Science 258: 480-484.
14. FISHMAN-LOBELL, J., N. RUDIN and J. E. HABER, 1992 Two alternative pathways of double-strand break repair that are kinetically separable and independently modulated. Mol. Cell. Biol. 12: 1292-1303.
15. FU, Y. H., D. P. KUHL, A. PIZZUTI, M. PIERETTI, J. S. SUTCLIFFE et al. 1991 Variation of the CGG repeat at the fragile X site results in genetic instability: resolution of the Sherman paradox. Cell 67: 1047-1058.
16. FU, Y. H., A. PIZZUTI, R. FENWICK, JR., J. KING, S. RAJNARAYAN et al. 1992 An unstable triplet repeat in a gene related to myotonic muscular dystrophy. Science 255: 1256-1258.
17. FUKUCHI, K., G. M. MARTIN and R. MONNAT, JR., 1989 Mutator phenotype of Werner syndrome is characterized by extensive deletions. Proc. Natl. Acad. Sci. USA 86: 5893-5897.
18. GAME, J. C., and B. S. COX, 1971 Allelism tests of mutants affecting sensitivity to radiation in yeast and a proposed nomenclature. Mutat. Res. 6: 37-55.
19. GANGLOFF, S., H. ZOU and R. ROTHSTEIN, 1996 Gene conversion plays the major role in controlling the stability of large tandem repeats in yeast. EMBO J. 15: 1715-1725.
20. GIETZ, D., A. ST. JEAN, R. A. WOODS and R. H. SCHIESTL, 1992 Improved method for high efficiency transformation of intact yeast cells. Nucleic Acids Res. 20: 1425.
21. HABER, J. E., and M. HEARN. 1985 RAD52-independent mitotic gene conversion in Saccharomyces cerevisiae frequently results in chromosomal loss. Genetics 111: 7-22.
22. HALUSKA, F. G., S. FINVER, Y. TSUJIMOTO and C. M. CROCE, 1986 The t(8; 14) chromosomal translocation occurring in B-cell malignancies results from mistakes in V-D-J joining. Nature 324: 158-161.
23. HARLEY, H. G., J. D. BROOK, S. A. RUNDLE, S. CROW, W. REARDON et al. 1992 Expansion of an unstable DNA region and phenotypic variation in myotonic dystrophy. Nature 355: 545-546.
24. HEYER, W. D., M. R. RAO, L. F. ERDILE, T. J. KELLY and R. D. KOLODNER, 1990 An essential Saccharomyces cerevisiae single-stranded DNA binding protein is homologous to the large subunit of human RP-A. EMBO J. 9: 2321-2329.
25. HOEKSTRA, M. F., T. NAUGHTON and R. E. MALONE, 1986 Properties of spontaneous mitotic recombination occurring in the presence of the rad52-1 mutation of Saccharomyces cerevisiae. Genet. Res. 48: 9-17.
26. HOFFMAN, C. S. and F. WINSTON, 1987 A ten-minute DNA preparation efficiently releases autonomous plasmids for transformation of Escherichia coli. Gene 57: 267-272.
27. HUNTINGTON'S DISEASE COLLABORATIVE RESEARCH GROUP, 1993 A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes. Cell 72: 971-983.
28. IVANOV, E. L., and J. E. HABER, 1995 RAD1 and RAD10, but not other excision repair genes, are required for double-strand break-induced recombination in Saccharomy cerevisiae. Mol. Cell. Biol. 15: 2245-2251.
29. JACKSON, J. A., and G. R. FINK, 1981 Gene conversion between duplicated genetic elements in yeast. Nature 292: 306-311.
30. JENSEN, R. E., and I. HERSKOWITZ, 1984 Directionality and regulation of cassette substitution in yeast. Cold Spring Harbor Symp. Quant. Biol. 49: 97-104.
31. JINKS-ROBERTSON, S., and T. D. PETES, 1986 Chromosomal translocations generated by high-frenquency meiotic recombination between repeated yeast genes. Genetics 114: 731-752.
32. KLEIN, H. L., 1988 Different types of recombination events are controlled by the RAD1 and RAD52 genes of Saccharomyces cerevisiae. Genetics 120: 367-377.
33. KLEIN, H. L., 1990 Genetic control of intrachromosomal recombination. Bioessays 17: 147-159.
34. KOSTRIKEN, R., J. N. STRATHERN, A. J. KLAR, J. B. HICKS and F. HEFFRON, 1983 A site-specific endonuclease essential for mating-type switching in Saccharomyces cerevisiae. Cell 35: 167-174.
35. LAKICH, D., H. KAZAZIAN, JR., S. E. ANTONARAKIS and J. GITSCHIER, 1993 Inversions disrupting the factor VIII gene are a common cause of severe haemophilia A. Nat. Genet. 5: 236-241.
36. LANGLOIS, R. G., W. L. BIGBEE, R. H. JENSEN and J. GERMAN, 1989 Evidenece for increased in vivo mutation and somatic recombination in Bloom's syndrome. Proc. Natl. Acad. Sci. USA 86: 670-674.
37. LA SPADA, A. R., E. M. WILSON, D. B. LUBAHN, A. E. HARDING and R. H. FISCHBECK. 1991 Androgen receptor gene mutations in X-linked spinal and bulbar muscular atrophy. Nature 352: 77-79.
38. LEA, D. E. and C. A. COULSON, 1949 The distribution in the numbers of mutants in bacterial populations. J. Genet. 49: 264-285.
39. LEHRMAN, M. A., D. W. RUSSELL, J. L. GOLDSTEIN and M. S. BROWN, 1986 Exon-Alu recombination deletes 5 kilobases from the low density lipoprotein receptor gene, producing a null phenotype in familial hypercholesterolemia. Proc. Natl. Acad. Sci. USA 83: 3679-3683.
40. MALONE, R. E., and R. E. ESPOSITO, 1980 The RAD52 gene is required for homothallic interconversion of mating types and spontaneous mitotic recombination in yeast. Proc. Natl. Sci. USA 77: 503-507.
41. MALONE, R. E., B. A. MONTELONE, C. EDWARDS, K. CARNEY and M. F. HOEKSTRA, 1988 A reexamination of the role of the RAD52 gene in spontaneous mitotic recombination. Curr. Genet. 14: 211-223.
42. MCDONNELL, M. W., M. N. SIMON and F. W. STUDIER, 1977 Analysis of restriction fragments of T7 DNA and determination of molecular weights by electrophoresis in neutral and alkaline gels. J. Mol. Biol. 110: 119-146.
43. MELTON, D. A., P. A. KRIEG, M. R. REBAGLIATI, T. MANIATIS, K. ZINN et al. 1984 Efficient in vitro synthesis of biologically active RNA and RNA hybridization probes from plasmids containing a bacteriophage SP6 promoter. Nucleic Acids Res. 12: 7035-7056.
44. MEYN, M. S., 1993 High spontaneous intrachromosomal recombination rates in ataxia-telanglectasia. Science 260: 1326-1330.
45. MONNAT, R. J., JR., 1992 Werner syndrome: molecular genetic and mechanistic hypotheses. Exp. Gerontol. 27: 447-453.
46. MORTENSEN, U. H., C. BENDIXEN, I. SUNJEVARIC and R. ROTHSTEIN, 1990 DNA strand annealing is promoted by the yeast Rad52 protein. Proc. Natl. Acad. Sci. USA 93: 10729-10734.
47. NASSIE, N., J. PENNEY, S. PAL, W. R. ENGELS and G. B. GROOR, 1994 Efficient copying of nonhomologous sequences from ectopic sites via P-element-induced gap repair. Mol. Cell. Biol. 14: 1613-1625.
48. NEW, J. H., T. SUGIYAMA, E. ZAITSEVA and S. C. KOWALCZYKOWSKI, 1998 Rad52 protein stimulates DNA strand exchange by Rad51 and replication protein A. Nature 391: 407-410.
49. ORR-WEAVER, T. L., J. W. SZOSTAK and R. J. ROTHSTEIN, 1981 Yeast transformation: a model system for the study of recombination. Proc. Natl. Acad. Sci. USA 78: 6354-6358.
50. OZENBERGER, B. A., and G. S. Roeder. 1991 A unique pathway of double-strand break repair operates in tandemly repeated genes. Mol. Cell. Biol. 11: 1222-1231.
51. PÂQUES, F., W. Y. LEUNG and J. E. HABER, 1998 Expansions and contractions in a tandem repeat induced by double-strand break repair. Mol. Cell. Biol. 18: 2045-2054.
52. PRADO, F., and A. AGUILERA, 1995 Roll-of reciprocal exchange, one-ended invasion crossover and single-strand annealing on inverted and direct repeat recombination in yeast: different requirements for the RAD1, RAD10, and RAD52 genes. Genetics 139: 109-123.
53. RESNICK, M. A., 1969 Genetic control of radiation sensitivity in Saccharomyces cerevisiae. Genetics 62: 519-531.
54. RESNICK, M. A., and P. MARTIN, 1976 The repair of double-strand breaks in the nuclear DNA of Sacchromyces cerevisiae and its genetic-control. Mol. Gen. Genet. 143: 119-129.
55. REYNOLDS, R. J., and E. C. FREIDBERG, 1981 Molecular mechanisms of pyrimidine dimer excision in Saccharomyces cerevisiae, incision of ultraviolet-irradiated deoxyribonucleic acid in vivo. J. Bacteriol. 146: 692-704.
56. RUDIN, N., and J. E. HABER, 1988 Efficient repair of HO-induced chromosomal breaks in Saccharomyces cerevisiae by recombination between flanking homologous sequences. Mol. Cell. Biol. 8: 3918-3928.
57. SAMBROOK, J., E. F. FRITSCH and T. MANIATIS, 1989 Molecular Cloning: A Laboatory Manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
58. SCHIESTL, R. H., and S. PRAKASH, 1988 RAD1, an excision repair gene of Saccharomyces cerevisiae, is also involved in recombination. Mol. Cell. Biol. 8: 3619-3626.
59. SHERMAN, F., 1991 Getting started with yeast, pp. 3-21 in Guide to Yeast Genetics and Molecular Biology, edited by C. GUTHRIE and G. R. GINK. Academic Press, San Diego, CA.
60. SHERMAN, F., G. R. FINK and J. B. HICKS, 1986 Methods in Yeast Genetics. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
61. SHINOHARA, A., and T. OGAWA, 1998 Stimulation by Rad52 of yeast Rad52-mediated recombination. Nature 391: 404-407.
62. SMITH, J., and R. ROTHSTEIN, 1995 A mutation in the gene encoding the Saccharomyces cerevisiae single-stranded DNA-binding protein Rfa1 stimulates a RAD52-independent pathway for direct-repeat recombination. Mol. Cell. Biol. 15: 1632-1641.
63. SMITH, J., H. ZOU and R. ROTHSTEIN, 1995 PCR-based gene disruption in Saccharomyces cerevisiae. Methods Mol. Cell. Biol. 5: 270-277.
64. SOUTHERN, E. M., 1975 Detention of specific sequences among DNA fragments separated by gel electrophoresis. J. Mol. Biol. 98: 503-517.
65. SUGAWARA, N. and J. E. HABER, 1992 Characterization of double-strand break-induced recombination: homology requirements and single-stranded DNA formation. Mol. Cell. Biol. 12: 563-575.
66. SUNG, P., 1997a Function of yeast Rad52 protein as a mediator between replication protein A and the Rad51 recombinase. J. Biol. Chem. 272: 28194-28197.
67. SUNG, P., 1997b Yeast Rad55 and Rad57 proteins form a heterodimer that functions with replication protein A to promote DNA strand exchange by Rad51 recombinase. Genes Dev. 11: 1111-1121.
68. THOMAS, B. J., and R. ROTHSTEIN, 1989a Elevated recombination rates in transcriptionally active DNA. Cell 56: 619-630.
69. THOMAS, B. J., and R. ROTHSTEIN, 1989b The genetic control of direct-repeat recombination in Saccharomyces the effect of rad52 and rad1 on mitotic recombination at GAL10, a transcriptionally regulated gene. Genetics 123: 725-738.
70. TOMKINSON, A. E., A. J. BARDWELL, L. BARDWELL, N. J. TAPPE and E. C. FIEDBERG, 1993 Yeast DNA repair and recombination proteins Rad1 and Rad10 constitute a single-stranded-DNA endonuclease. Nature 362: 860-862.
71. WHITE, C. I., and J. E. HABER, 1990 Intermediates of recombination during mating type switching in Saccharomyces cerevisiae. EMBO J. 9: 663-673.