A T cell receptor (TCR) antagonist competitively inhibits serial TCR triggering by low-affinity ligands, but does not affect triggering by high-affinity anti-CD3 antibodies

European Journal of Immunology

Volumn 27, Issue 11, 1997, Pages 3080-3083

  Viola, Antonella ^a   Linkert, Susanne ^a   Lanzavecchia, Antonio ^a  

^a BASEL INSTITUTE FOR IMMUNOLOGY   (Switzerland)

Author keywords

Low and high affinity ligands; T cell receptor antagonism; T cell receptor downregulation; T cell receptor serial triggering

Indexed keywords

CD3 ANTIGEN; LIGAND; MONOCLONAL ANTIBODY CD3; PEPTIDE; RECEPTOR BLOCKING AGENT; SUPERANTIGEN; T LYMPHOCYTE RECEPTOR;

ANIMAL CELL; ANTIGEN PRESENTING CELL; ARTICLE; CELLULAR IMMUNITY; CONTROLLED STUDY; NONHUMAN; PRIORITY JOURNAL; RECEPTOR AFFINITY; T LYMPHOCYTE ACTIVATION;

ANTIBODIES, MONOCLONAL; ANTIGENS, CD3; BACTERIAL TOXINS; BINDING, COMPETITIVE; CLONE CELLS; DOWN-REGULATION; ENTEROTOXINS; HUMANS; LIGANDS; LYMPHOCYTE ACTIVATION; PEPTIDE FRAGMENTS; RECEPTORS, ANTIGEN, T-CELL; SUPERANTIGENS; T-LYMPHOCYTES;

EID: 0030715298     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/eji.1830271146     Document Type: Article

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