The relationship of hydroxyeicosatetraenoic acids and F2-isoprostanes to plaque instability in human carotid atherosclerosis

Journal of Clinical Investigation

Volumn 103, Issue 3, 1999, Pages 421-427

  Mallat, Ziad ^a   Nakamura, Tatsuji ^b   Ohan, Jeanny ^c   Lesèche, Guy ^c   Tedgui, Alain ^a   Maclouf, Jacques ^a   Murphy, Robert C ^b  

^a HÔPITAL LARIBOISIÈRE   (France)

^b NATIONAL JEWISH MEDICAL AND RESEARCH CENTER   (United States)

^c BEAUJON HOSPITAL   (France)

Author keywords

[No Author keywords available]

Indexed keywords

HYDROXYICOSATETRAENOIC ACID; ISOPROSTANE;

ARTICLE; ATHEROSCLEROSIS; ATHEROSCLEROTIC PLAQUE; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; ENDARTERECTOMY; ENZYME ACTIVITY; ENZYME MECHANISM; FEMALE; HUMAN; LIPID PEROXIDATION; MALE; MORBIDITY; MORTALITY; OXIDATIVE STRESS; PRIORITY JOURNAL; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; TANDEM MASS SPECTROMETRY;

EID: 0032959848     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI3985     Document Type: Article

References (37)

1. Fuster, V., Badimon, L., Badimon, J.J., and Chesebro, J.H. 1992. The pathogenesis of coronary artery disease and the acute coronary syndromes. N. Engl. J. Med. 326:242-230.
2. Fuster, V., Badimon, L,. Badimon, J.J., and Chesebro, J.H. 1992. The pathogenesis of coronary artery disease and the acute coronary syn-dromes. N. Engl. J. Med. 326:310-318.
3. Lee, R.T., and Libby, P. 1997. The unstable atheroma. Arterioscler. Thromb. Vasc. Biol. 17:1859-1867.
4. Steinberg, D. 1997. Low density lipoprotein oxidation and its pathobiological significance. J. Biol. Chem. 272:20963-20966.
5. Berliner, J.A., and Heinecke, J.W. 1996. The role of oxidized lipoproteins in atherogenesis. Free Radic. Biol. Med. 20:707-727.
6. Napoli, C., et al. 1997. Fatty streak formation occurs in human fetal aortas and is greatly enhanced by maternal hypercholesterolemia. Intimal accumulation of low density lipoprotein and its oxidation precede monocyte recruitment into early atherosclerotic lesions. J. Clin. Invest. 100:2680-2690.
7. Kühn, H., Belkner, J., Suzuki, H., and Yamamoto, S. 1994. Oxidative modification of human lipoproteins by lipoxygenases of different positional specificities. J. Lipid Res. 35:1749-1759.
8. Upston, J.M., Neuzil, J., Witting, P.K., Alleva, R., and Stocker, R. 1997. Oxidation of free fatty acids in low density lipoprotein by 15-lipoxygenase stimulates nonenzymatic, α-tocopherol-mediated peroxidation of cholesteryl esters. J. Biol. Chem. 272:30067-30074.
9. Yamamoto, S. 1992. Mammalian lipoxygenases: molecular structures and functions. Biochim. Biophys. Acta. 1128:117-131.
10. Ravalli, S., et al. 1995. Immunohistochemical demonstration of 15-lipoxygenase in transplant coronary artery disease. Arterioscler. Thromb. Vasc. Biol. 15:340-348.
11. Folcik, V.A., Nivar-Aristy, R.A., Krajewski, L.P., and Cachcart, M.K. 1995. Lipoxygenase contributes to the oxidation of lipids in human atherosclerotic plaques. J. Clin. Invest. 96:504-510.
12. Kühn, H., Heydeck, D., Hugou, I., and Gniwotta, C. 1997. In vivo action of 15-lipoxygenase in early stages of human atherogenesis. J. Clin. Invest. 99:888-893.
13. Herderick, S.J., et al. 1996. Macrophage-mediated 15-lipoxygenase expression protects against atherosclerosis development. J. Clin. Invest. 98:2201-2208.
14. Hoppe, G., Ravandi, A., Herrera, D., Kuksis, A., and Hoff, H.F. 1997. Oxidation products of cholesteryl linoleate are resistant to hydrolysis in macrophages, form complexes with proteins, and are present in human atherosclerotic lesions. J. Lipid Res. 38:1347-1360.
15. Suarna, S.C., Dean, R.T., Southwell-Keeley, P.T., Moore, D.E., and Stocker, R. 1997. Separation and characterization of cholesteryl oxo- and hydroxy-linoleate isolated from human atherosclerotic plaque. Free Radic. Res. 27:397-408.
16. Porter, NA., Caldwell, S.E., and Mills, K.A. 1995. Mechanisms of free radical oxidation of unsaturated lipids. Lipids. 10:277-290.
17. Hall, L.M., and Murphy, R.C. 1998. Analysis of oxidized molecular species of glycerophospholipids following treatment of red blood cell ghosts with t-butylhydroperoxide. Anal. Biochem. 258:184-194.
18. Nakamura, T., Bratton, D.L., and Murphy, R.C. 1997. Analysis of epoxyeicosatrienoic and monohydroxyeicosatetraenoic acids esterified to phospholipids in human red blood cells by electrospray tandem mass spectrometry. J. Mass Spectrom. 32:888-896.
19. Morrow, J.D., and Roberts, L.J., II. 1996. The isoprostanes: current knowledge and directions for future research. Biochem. Pharmacol. 51:1-9.
20. Patrono, C., and FitzGerald, G.A. 1997. Isoprostanes: potential markers of oxidant stress in atherothrombotic disease. Arterioscler. Thromb. Vasc. Biol. 17:2309-2315.
21. Harrison, K., and Murphy, R.C. 1995. Isoleukotrienes: biologically active free radical products of lipid peroxidation. J. Biol. Chem. 270:17273-17278.
22. Jira, W., Spiteller, G., Carson, W., and Schramm, A. 1998. Strong increase in hydroxy fatty acids derived from linoleic acid in human low density lipoproteins of atherosclerotic patients. Chem. Phys. Lipids. 91:1-11.
23. 2-isoprostanes in human atherosclerotic lesions. J. Clin. Invest. 100:2028-2034.
24. Murphy, R.C., and Clay, K.C. 1990. Preparation of labeled molecules by exchange with oxygen-18 water. Methods Enzymol. 193:338-348.
25. Young, B., et al. 1996. An analysis of perioperative surgical mortality and morbidity in the Asymptomatic Carotid Atherosclerosis Study. Stroke. 27:2216-2224.
26. Moore, W.S., et al. 1995. Guidelines for carotid endarterectomy. A multidisciplinary consensus statement from the Ad Hoc Committee, American Heart Association. Stroke. 26:188-201.
27. No authors listed. 1994. Clinical advisory: carotid endarterectomy for patients with asymptomatic internal carotid artery stenosis. Stroke. 25:2523-2524.
28. Rose, H.G., and Oklander, M. 1965. Improved procedure for the extraction of lipids from human erythrocytes. J. Lipid Res. 6:428-431.
29. Morrison, W.R. 1964. A fast, simple and reliable method for the microdetermination of phosphorus in biological materials. Anal. Biochem. 7:218-224.
30. Suarna, C., Dean, R.T., May, J., and Stocker, R. 1995. Human atherosclerotic plaque contains both oxidized lipids and relatively large amounts of alpha-tocopherol and ascorbate. Artherioscler. Thromb. Vasc. Biol. 15:1616-1624.
31. 2-isoprostanes, are present in increased amounts in human atherosclerotic lesions. Arterioscler. Thromb. Vasc. Biol. 17:3236-3241.
32. 2-isoprostane receptors on rat vascular smooth muscle cells. Am. J. Physiol. 264:C1619-C1624.
33. O'Flaherty, J.T., and Rossi, A.G. 1993. 5-hydroxyicosatetraenoate stimulates neutrophils by a stereospecific, G protein-linked mechanism. J. Biol. Chem. 268:14708-14714.
34. Rosolowsky, M., Falck, J.R., Willerson, J.F., and Campbell, W.B. 1990. Synthesis of lipoxygenase and epoxygenase products of arachidonic acid by normal and stenosed canine coronary arteries. Circ. Res. 66:608-621.
35. Carr, S., Farb, A., Pearce, W.H., Virmani, R., and Yao, J.S. 1996. Atherosclerotic plaque rupture in symptomatic carotid artery stenosis. J. Vasc. Surg. 23:755-765.
36. Small, D.M. 1988. Progression and regression of atherosclerotic lesions. Insights from lipid physical biochemistry. Arteriosclerosis. 8:103-129.
37. Harats, D., Mulkins, M.A., and Sigal, E. 1995. A possible role for 15-lipoxygenase in atherogenesis. Trends Cardiovasc. Med. 5:29-36.