Altered immune response of interferon regulatory factor 1-deficient mice against Plasmodium berghei blood-stage malaria infection

Infection and Immunity

Volumn 67, Issue 5, 1999, Pages 2277-2283

  Tan, Rosemary Sok Pin ^a   Feng, Chiguang ^b   Asano, Yoshihiro ^b   Kara, Anna Ursula ^a  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^b EHIME UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; INTERFERON REGULATORY FACTOR 1; INTERLEUKIN 12; NITRIC OXIDE; NITRIC OXIDE SYNTHASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; HOST RESISTANCE; IMMUNE RESPONSE; MALARIA; MOUSE; NONHUMAN; PARASITEMIA; PLASMODIUM BERGHEI; PRIORITY JOURNAL; SURVIVAL RATE;

EID: 0032948138     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/iai.67.5.2277-2283.1999     Document Type: Article

References (48)

1. Ahvazi, B. C., P. Jacobs, and M. M. Stevenson. 1995. Role of macrophage-derived NO in suppression of lymphocyte proliferation during blood stage malaria. J. Leukoc. Biol. 58:23-31.
2. Beckerman, K. P., H. W. Rogers, J. A. Corbett, R. D. Shreiber, M. L. McDaniel, and E. R. Unanue. 1993. Release of nitric oxide during the T cell-independent pathway of macrophage activation. Its role in resistance to Listeria monocytogenes. J. Immunol. 150:888-895.
3. Boockvar, K. S., D. L. Granger, R. M. Poston, M. Maybodi, M. K. Washington, J. B. Hibbs, Jr., and R. L. Kurlander. 1994. Nitric oxide produced during murine listeriosis is protective. Infect. Immun. 62:1089-1100.
4. Ding, A. H., C. F. Nathan, and D. J. Stuehr. 1988. Release of reactive nitrogen intermediates and oxygen intermediates from mouse peritoneal macrophages. J. Immunol. 141:2407-2412.
5. Fujita, T., Y. Kimura, M. Miyamoto, E. L. Barsoumian, and T. Taniguchi. 1989. Induction of endogenous IFN-α and IFN-β genes by a regulatory transcription factor, IRF-1. Nature 337:270-272.
6. Fujita, T., L. F. Reis, N. Watanabe, Y. Kimura, T. Taniguchi, and J. Vilcek. 1989. Induction of the transcription factor IRF-1 and interferon-beta mRNAs, by cytokines and activators of second-messenger pathways. Proc. Natl. Acad. Sci. USA 86:9936-9940.
7. 15nitrate in biological fluids. Anal. Biochem. 126:131-138.
8. Gregory, S. H., E. J. Wing, R. A. Hoffman, and R. L. Sher. 1993. Reactive nitrogen intermediates suppress the primary immunologic response to Listeria. J. Immunol. 150:2901-2909.
9. Harada, H., T. Fujita, M. Miyamoto, Y. Kimura, M. Maruyama, T. Miyata, and T. Taniguchi. 1989. Structurally similar but functionally distinct factors, IRF-1 and IRF-2, bind to the same regulatory elements of IFN and IFN-inducible genes. Cell 58:729-739.
10. Harada, H., K. Willison, J. Sakakibara, M. Miyamoto, T. Fujita, and T. Taniguchi. 1990. Absence of the type I IFN system in EC cells: transcriptional activator (IRF-1) and repressor (IRF-2) genes are developmentally regulated. Cell 63:303-312.
11. Hoffman, S. L., J. M. Crutcher, S. K. Puri, A. A. Ansari, F. Villinger, E. D. Franke, P. P. Singh, F. Finkelman, M. K. Gately, G. P. Dutta, and M. Sedagah. 1997. Sterile protection of monkeys against malaria after administration of IL-12. Nat. Med. 3:80-83.
12. Itoh, S., H. Harada, Y. Nakamura, R. White, and T. Taniguchi. 1991. Assignment of the human interferon regulatory factor-1 (IRF-1) gene to chromosome 5q23-31. Genomics 10:1097-1099.
13. Jacobs, P., D. Radzioch, and M. M. Stevenson. 1995. Nitric oxide expression in the spleen, but not in the liver correlates with resistance to blood-stage malaria in mice. J. Immunol. 155:5306-5313.
14. Jacobs, P., D. Radzioch, and M. M. Stevenson. 1996. In vivo regulation of nitric oxide production by tumor necrosis factor alpha and gamma interferon, but not by interleukin-4, during blood-stage malaria in mice. Infect. Immun. 64:44-49.
15. Kamijo, R., H. Harada, T. Matsuyama, M. Posland, J. Gerecitano, D. Shapiro, J. Le, T. Kimura, S. J. Green, T. W. Mak, T. Taniguchi, and J. Vilcek. 1994. Requirement for transcription factor IRF-1 in NO synthase induction in macrophages. Science 263:1612-1615.
16. Karmann, K., W. Min, W. C. Fanslow, and J. S. Pober. 1996. Activation and homologous desensitization of human endothelial cells by CD40 ligand, tumor necrosis factor and interleukin-1. J. Exp. Med. 184:173-182.
17. -/- mice. J. Immunol. 156:636-643.
18. Kimura, T., K. Nakayama, J. Penninger, M. Kitagawa, H. Harada, T. Matsuyama, N. Tanaka, R. Kamijio, J. Vilcek, T. W. Mak, and T. Taniguchi. 1994. Involvement of the IRF-1 transcription factor in antiviral responses to interferons. Science 264:1921-1924.
19. Lamphier, M., and T. Taniguchi. 1994.The transcriptional factors IRF-1 and IRF-2. Linking the interferon response and cell growth control. Immunologist 2:(5):167-171.
20. Li, R.-M., A. U. Kara, and R. Sinniah. 1998. Dysregulation of cytokine expression in tubulointerstitial nephritis associated with murine malaria. Kidney Int. 53:845-852.
21. Liew, F. Y., S. Millott, C. Parkinson, R. M. J. Palmer, and S. Moncada. 1990. Macrophage killing of Leishmania parasite in vivo is mediated by nitric oxide from L-arginine. J. Immunol. 144:4794-4797.
22. Lohoff, M., D. Ferrick, H.-W. Mittrucker, G. S. Duncan, S. Bischof, M. Rollinghoff, and T. W. Mak. 1997. Interferon regulatory factor-1 is required for a T helper 1 immune response in vivo. Immunity 6:681-689.
23. Martins, G. A., M. A. Cardoso, J. C. Aliberti, and J. S. Silva. 1998. Nitric oxide-induced apoptotic cell death in the acute phase of Trypanosoma cruzi infection in mice. Immunol. Lett. 63:113-120.
24. Matsuyama, T., T. Kimura, M. Kitagawa, K. Pfeffer, T. Kawakami, N. Watanabe, T. M. Kundig, R. Amakawa, K. Kishihara, A. Wakeham, J. Potter, C. L. Furlonger, A. Narendan, H. Suzuki, P. S. Ohashi, C. J. Paige, T. Taniguchi, and T. W. Mak. 1993. Targeted disruption of IRF-1 or IRF-2 results in abnormal type I IFN gene induction and aberrant lymphocyte development. Cell 75:83-97.
25. Mellouk, S., S. J. Green, C. A. Nacy, and S. L. Hoffman. 1991. IFN-γ inhibits development of Plasmodium berghei exoerythrocyte stages in hepatocytes by an L-arginine-dependence effector mechanism. J. Immunol. 146:3911-3976.
26. Misko, T. P., W. M. Moore, T. P. Kasten, G. A. Nichols, J. A. Corbett, R. G. Tilton, M. L. McDaniel, J. R. Williamson, and M. G. Currie. 1993. Selective inhibition of the inducible nitric oxide synthase by aminoguanidine. Eur. J. Pharmacol. 233:119-125.
27. Miyamoto, M., T. Fujita, Y. Kimura, M. Maruyama, H. Harada, V. Sudo, T. Miyata, and T. Taniguchi. 1988. Regulated expression of a gene encoding a nuclear factor, IRF-1 that specifically binds to IFN-β gene regulatory elements. Cell 54:903-913.
28. Moncada, S., R. M. J. Palmer, and E. A. Higgs. 1991. Nitric oxide: physiology, pathophysiology, and pharmacology. Pharmacol. Rev. 43:109-141.
29. Nathan, C., and Q. Xie. 1994. Regulation of biosynthesis of nitric oxide. J. Biol. Chem. 269:13725-13728.
30. Nussler, A. K., T. R. Billar, R. A. Hoffman, D. A. Gella, R. Selby, J. Madariaga, and R. L. Simmons. 1992. Stimulation of the nitric oxide synthase pathway in human hepatocytes by cytokines and endotoxin. J. Exp. Med. 176:261-264.
31. Rockett, K. A., M. M. Awburn, B. B. Aggarwal, W. B. Cowden, and I. A. Clark. 1992. In vivo induction of nitrite and nitrate by tumor necrosis factor, lymphotoxin, and interleukin-1: possible roles in malaria. Infect. Immun. 60:3725-3730.
32. Rockett, K. A., M. M. Awburn, E. J. Rockett, W. B. Cowden, and I. A. Clark. 1994. Possible role of nitric oxide in malarial immunosuppression. Parasite Immunol. 16:243-249.
33. Saito, S., and F. Sendo. 1997. Aminoguanidine, a nitric oxide synthase inhibitor increases the mortality of mice intraperitoneally injected with limiting dosages of virulent Plasmodium berghei NK65. Parasitol. Int. 46:111-113.
34. Salkowski, C. A., S. A. Barber, G. R. Detore, and S. N. Vogel. 1996. Differential deregulation of nitric oxide production in macrophages with targeted disruptions in IFN regulatory factor-1 and -2 genes. J. Immunol. 156:3107-3110.
35. Sedagah, M., F. Finkelman, and S. L. Hoffman. 1994. IL-12 induction of IFN-γ-dependent protection against malaria. Proc. Natl. Acad. Sci. USA 91: 10700-10702.
36. Stenger, S., H. Thering, M. Rollinghoff, and C. Bogdan. 1994. Tissue expression of inducible nitric oxide synthase is closely associated with resistance to Leishmania major. J. Exp. Med. 180:783-793.
37. Stevenson, M. M., M. F. Tam, S. F. Wolf, and A. Sher. 1995. IL-12-induced protection against blood-stage Plasmodium chabaudi AS requires IFN-γ and TNF-α and occurs via a nitric oxide-dependent mechanism. J. Immunol. 155: 2545-2556.
38. Stuehr, D. J., and M. A. Marietta. 1985. Mammalian nitrate biosynthesis: mouse macrophages produce nitrite and nitrate in response to Escherichia coli lipopolysaccharide. Proc. Natl. Acad. Sci. USA 82:7738-7742.
39. Taki, S., T. Sato, K. Ogasawara, T. Fukuda, M. Sato, S. Hida, G. Suzuki, M. Mitsuyama, E.-H. Shin, S. Kojima, T. Taniguchi, and V. Asano. 1997. Multistage regulation of Th1-type immune responses by the transcription factor IRF-1. Immunity 6:673-679.
40. Tamara, T., M. Ishihara, M. S. Lamphier, N. Tanaka, I. Oishi, S. Aizawa, T. Matsuyama, T. W. Mak, S. Taki, and T. Taniguchi. 1995. An IRF-1-dependent pathway of DNA damage-induced apoptosis in mitogen-activated T lymphocytes. Nature 376:596-599.
41. Tan, R. S.-P., T. Taniguchi, and H. Harada. 1996. Identification of the lysyl oxidase gene as a target of the antioncogenic transcription factor, IRF-1, and its possible role in tumor suppression. Cancer Res. 56:2417-2421.
42. 41a. Tan, R. S.-P., et al. Unpublished data.
43. Tanaka, N., T. Kawakami, and T. Taniguchi. 1993. Recognition DNA sequences of interferon regulatory factor 1 (IRF-1) and IRF-2, regulators of cell growth and the Interferon system. Mol. Cell Biol. 13:4531-4538.
44. Tanaka, N., M. Ishihara, M. Kitagawa, H. Harada, T. Kimura, T. Matsuyama, M. S. Lamphier, S. Aizawa, T. W. Mak, and T. Taniguchi. 1994. Cellular commitment to oncogene-induced transformation or apoptosis is dependent on the transcription factor IRF-1. Cell 77:829-839.
45. Tanaka, N., M. Ishihara, M. S. Lamphier, H. Nozawa, T. Matsuyama, T. W. Mak, S. Aizawa, T. Tokino, M. Oren, and T. Taniguchi. 1996. Cooperation of the tumour suppressors IRF-1 and p53 in response to DNA damage. Nature 382:816-818.
46. Trinchieri, G. 1993. Interleukin-12 and its role in the generation of ThI cells. Immunol. Today 14:335-338.
47. Willman, C. L., C. E. Sever, M. G. Pallavicini, H. Harada, N. Tanaka, M. L. Slovak, H. Tamamoto, K. Harada, T. C. Meeker, A. F. List, and T. Taniguchi. 1993. Deletion of IRF-1, mapping to chromosome 5q31.1, in human leukemia and preleukemic myelodysplasia. Science 259:968-971.
48. Yap, M. W. C., A. U. Kara, B. ten Heggeler-Bordier, R. C. Y. Ting, and T. M. C. Tan. 1997. Partial nucleotide sequence and organisation of extra-chromosomal plastid-like DNA in Plasmodium berghei. Gene 200:91-98.