Immunoglobulin gene associated chromosomal translocations in B-cell derived tumors

Current Topics in Microbiology and Immunology

Volumn 246, Issue , 1999, Pages 161-167

  Klein, G ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

B LYMPHOCYTE; BURKITT LYMPHOMA; CHROMOSOME TRANSLOCATION; CONFERENCE PAPER; HUMAN; NONHUMAN; ONCOGENE C MYC; PATHOGENESIS; PLASMACYTOMA; PRIORITY JOURNAL;

EID: 0032947209     PISSN: 0070217X     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-3-642-60162-0_20     Document Type: Conference Paper

References (10)

1. Magrath, I. (1990) The pathogenesis of Burkitt's lymphoma. Advances in Cancer Research, 55:133-270.
2. Hiom K. Melek M, Gellert M (1998) DNA transposition by the RAG1 and RAG2 proteins: a possible source of oncogenic translocations. Cell 94:463-470.
3. Agrawall A. Eastman Q. Schatz D. (1998) Transposition mediated by RAG1 and RAG2 and its implications for the evolution of the immune system. Nature 394:744-751.
4. Goossens T. Klein U. Küppers R. (1998) Frequent occurrence of deletions and duplications during somatic hypermutation:Implications for oncogene translocations and heavy chain disease. Proc. Natl. Acad. Sci.USA 95:2463-2468.
5. Limpens J. Stad R. Vos C. de Vlaam C. de Jong D. van Ommen GJ. Schuuring E. Kluin PM. (1995) Lymphoma-associated translocation t(14;18) in blood B cells of normal individuals. Blood 85;2528-36.
6. Müller J. Janz S. Goedert J. Potter M. Rabkin C. (1995) Persistence of immunoglobulin heavy chain/c-myc recombination-positive lymphocyte clones in the blood of human immunodeficiency virus-infected homosexual men. Proc. Natl. Acad. Sci. USA 92:6577-6581.
7. Janz S. Muller J. Shaughnessy J. Potter M. (1993) Detection of recombinations between c-myc and immunoglobulin switch alpha in murine plasma cell tumors and preneoplastic lesions by polymerase chain reaction. Proc. Natl. Acad. Sci. USA 90:7361-5.
8. Müller J. Mushinski E. Williams J, Hausner P. (1997) Immunoglobulin/myc recombinations in murine Peyer's patch follicles. Genes, Chromosomes & Cancer 20:1-8.
9. Roschke V. Kopantzev E. Dertzbaugh M. Rudikoff S. (1997) Chromosomal translocations deregulating c-myc are associated with normal immune responses. Oncogene 14:3011-3016.
10. Silva, S. Sugiyama H. Babonits M. Wiener F. Klein G. (1991) Differential susceptibility of BALB/c and DBA/2 cells to plasmacytoma induction in reciprocal chimeras. International Journal of Cancer 49:224-228.