Effects of duodenal distension on antropyloroduodenal pressures and perception are modified by hyperglycemia

American Journal of Physiology - Gastrointestinal and Liver Physiology

Volumn 276, Issue 3 39-3, 1999, Pages

  Lingenfelser, T ^a   Sun, W M ^a   Hebbard, G S ^a   Dent, J ^a   Horowitz, M ^a  

^a NONE

Author keywords

Duodenum; Gastrointestinal sensation; Pylorus

Indexed keywords

GLUCOSE; INSULIN;

ADULT; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DUODENUM MOTILITY; FEMALE; GASTROINTESTINAL SECRETION; GASTROINTESTINAL TRACT FUNCTION; GLUCOSE BLOOD LEVEL; HUMAN; HUMAN EXPERIMENT; HUNGER; HYPERGLYCEMIA; INSULIN BLOOD LEVEL; INTESTINE DISTENSION; INTESTINE PRESSURE; MALE; NAUSEA; NORMAL HUMAN; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SINGLE BLIND PROCEDURE;

EID: 0032945251     PISSN: 01931857     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpgi.1999.276.3.g711     Document Type: Article

References (45)

1. Anderson, E. A., R. P. Hoffman, T. W. Balon, C. A. Sinkey, and A. L. Mark. Hyperinsulinemia produces both sympathetic neural activation and vasodilation in normal humans. J. Clin. Invest. 87: 2246-2252, 1991.
2. Andrews, J. M., C. K. Rayner, S. Doran, G. S. Hebbard, and M. Horowitz. Physiological changes in blood glucose affect appetite and pyloric motility during intraduodenal lipid infusion. Am. J. Physiol. 275 (Gastrointest. Liver Physiol. 38): G797-G804, 1998.
3. Azpiroz, F., and J. R. Malagelada. Perception and reflex relaxation of the stomach in response to gut distension. Gastroenterology 98: 1193-1198, 1990.
4. Barnett, J. L., and C. Owyang. Serum glucose concentration as a modulator of interdigestive gastric motility. Gastroenterology 94: 739-744, 1988.
5. Boeckxstaens, G., M. Horowitz, H. Bermingham, and R.H. Holloway. Physiological changes in blood glucose affect esophageal motility and sensation in normal subjects. Neurogastroenterol. Motil. 9: 239-246, 1997.
6. De Boer, S., A. Masclee, M. C. Jebbink, J. Schipper, H. H. Lemkes, J. B. Jansen, and C. B. Lamers. Effect of acute hyperglycaemia on gall bladder contraction induced by cholecystokinin in humans. Gut 34: 1128-1132, 1993.
7. De Boer, S. Y., A. A. Masclee, W. F. Lam, and C. B. Lamers. Effect of acute hyperglycemia on esophageal motility and lower esophageal sphincter pressure in humans. Gastroenterology 103: 775-780, 1992.
8. De Boer, S. Y., A. A. Masclee, W. F. Lam, H. H. Lemkes, J. Schipper, M. Frolich, J. B. Jansen, and C. B. Lamers. Effect of hyperglycaemia on gallbladder motility in type 1 (insulin-dependent) diabetes mellitus. Diabetologia 37: 75-81, 1994.
9. Edelbroek, M., M. Horowitz, J. Dent, W. M. Sun, C. Malbert, A. Smout, and L. Akkermans. Effects of duodenal distension on fasting and postprandial antropyloroduodenal motility in humans. Gastroenterology 106: 583-592, 1994.
10. Eliasson, B., E. Bjornsson, V. Urbanavicius, H. Andersson, J. Fowlein, and S. Attvall. Hyperinsulinaemia impairs gastrointestinal motility and slows carbohydrate absorption. Diabetologia 38: 79-85, 1995.
11. Feinle, C., M. D'Amato, and N. W. Read. Cholecystokinin-A receptors modulate gastric sensory and motor responses to gastric distention and duodenal lipid. Gastroenterology 110: 1379-1385, 1996.
12. Fraser, R., M. Horowitz, and J. Dent. Hyperglycaemia stimulates pyloric motility in normal subjects. Gut 32: 475-478, 1991.
13. Fraser, R., M. Horowitz, A. Maddox, and J. Dent. Organization of antral pyloric and duodenal motility in patients with gastroparesis. J. Gastrointest. Motil. 5: 167-175, 1993.
14. Fraser, R., M. Horowitz, A. F. Maddox, P. E. Harding, B. E. Chatterton, and J. Dent. Hyperglycaemia slows gastric emptying in type 1 (insulin-dependent) diabetes mellitus. Diabetologia 33: 675-680, 1990.
15. Groop, L., L. Luizi, R. DeFronzo, and A. Melander. Hyperglycemia and absorption of sulphonylurea drugs. Lancet ii: 129-130, 1989.
16. Grundy, D. The integration of physiological mechanisms: extrinsic innervation. In: Gastrointestinal Motility. London: Blackwell, 1989, p. 35-56.
17. Hasler, W. L., H. C. Soudah, G. Dulai, and C. Owyang. Mediation of hyperglycemia-evoked gastric slow-wave dysrhthymias by endogenous prostaglandins. Gastroenterology 108: 727-736, 1995.
18. Hebbard, G. S., M. Samsom, and J. M. Andrews, D. Carman, B. Tansell, W. M. Sun, J. Dent, and M. Horowitz. Hyperglycemia affects gastric electrical rhythm and nausea during intraduodenal triglyceride infusion. Dig. Dis. Sci. 42: 568-575, 1997.
19. Hebbard, G. S., M. Samsom, W.-M. Sun, J. Dent, and M. Horowitz. Hyperglycemia affects proximal gastric motor and sensory function during small intestinal triglyceride infusion. Am. J. Physiol. 271 (Gastrointest. Liver Physiol. 34): G814-G819, 1996.
20. Hebbard, G. S., W.-M. Sun, J. Dent, and M. Horowitz. Hyperglycemia affects proximal gastric motor and sensory function in normal subjects. Eur. J. Gastroenterol. Hepatol. 8: 211-217, 1996.
21. Heddle, R., P. Collins, J. Dent, M. Horowitz, N. W. Read, B. E. Chatterton, and L. Houghton. Motor mechanisms associated with slowing of the gastric emptying of a solid meal by an intraduodenal lipid infusion. J. Gastroenterol. Hepatol. 4: 437-447, 1989.
22. Heddle, R., J. Dent, J. Toouli, and N. W. Read. Topography and measurement of pyloric pressure waves and tone in humans. Am. J. Physiol. 255 (Gastrointest. Liver Physiol. 18): G490-G497, 1988.
23. Horowitz, M., P. E. Harding, A. F. Maddox, J. M. Wishart, L. M. A. Akkermans, B. E. Chatterton, and D. J. C. Shearman. Gastric and oesophageal emptying in patients with type 2 (non-insulin dependent) diabetes mellitus. Diabetologia 32: 151-159, 1989.
24. Horowitz, M., A. F. Maddox, J. M. Wishart, P. E. Harding, B. E. Chatterton, and D. J. C. Shearman. Relationships between oesophageal transit and solid and liquid gastric emptying in diabetes mellitus. Eur. J. Nucl. Med. 18: 229-234, 1991.
25. Horowitz, M., J. M. Wishart, K. L. Jones, and G. S. Hebbard. Gastric emptying in diabetes: an overview. Diabet. Med. 13: S16-S22, 1996.
26. Iovino, P., F. Azpiroz, E. Dominigo, and J. R. Malagelada. The sympathetic nervous system modulates perception and reflex responses to gut distension in humans. Gastroenterology 108: 680-686, 1995.
27. Jones, K. L., M. Horowitz, M. Berry, J. Wishart, S. M. Doran, and S. Guha. The blood glucose concentration influences postprandial fullness in insulin-dependent diabetes mellitus. Diabetes Care 20: 1141-1146, 1997.
28. Kim, C. H., F. P. Kennedy, M. Camilleri, A. R. Zinsmeister, and D. J. Ballard. The relationship between clinical factors and gastrointestinal dysmotility in diabetes mellitus. J. Gastrointest. Motil. 3: 268-272, 1991.
29. Kirchgessner, A., and M.-T. Liu. Identification and characterisation of gluco-responsive neurons in the rat small intestine (Abstract). Gastroenterology 114: A3204, 1998.
30. Liang, K. Y., and S. L. Zeger. Longitudinal data analysis using generalized linear models. Biometrika 73: 13-22, 1986.
31. Lingenfelser, T., D. Overkamp, W. Renn, U. Buettner, K. Kimmerle, A. Schmalfuss, and B. Jakober. Insulin-associated modulation of neuroendocrine counterregulation, hypoglycemia perception, and cerebral function in insulin-dependent diabetes mellitus: evidence for an intrinsic effect of insulin on the central nervous system. J. Clin. Endocrinol. Metab. 81: 1197-1205, 1996.
32. MacGregor, I. L., R. Gueller, H. D. Watts, and J. H. Meyer. The effect of acute hyperglycemia on gastric emptying in man. Gastroenterology 70: 190-196, 1976.
33. Mayer, E. A., and H. E. Raybould. Role of visceral afferent mechanisms in functional bowel disorders. Gastroenterology 99: 1688-1704, 1990.
34. Mearin, F., M. Camilleri, and J. R. Malagelada. Pyloric dysfunction in diabetics with recurrent nausea and vomiting. Gastroenterology 90: 1919-1925, 1986.
35. Oster-Jorgensen, E., S. Pedersen, and M. Larsen. The influence of induced hyperglycemia on gastric emptying in healthy humans. Scand. J. Clin. Lab. Invest. 35: 831-836, 1990.
36. Russo, A., R. Fraser, and M. Horowitz. The effect of acute hyperglycemia on small intestinal motility in normal subjects. Diabetologia 39: 984-989, 1996.
37. Russo, A., W.-M. Sun, Y. Sattawatthamrong, R. Fraser, M. Horowitz, J. M. Andrews, and N. W. Read. Acute hyperglycemia affects anorectal motor and sensory function in normal subjects. Gut 41: 494-499, 1997.
38. Samsom, M., L. M. A. Akkermans, R. J. A. Jebbink, H. Van Isselt, G. P. Van Berge-Henegouwen, and A. J. P. M. Smout. Gastrointestinal motor mechanisms in hyperglycemia-induced delayed gastric emptying in type I diabetes mellitus. Gut 40: 641-646, 1997.
39. Samsom, M., G. Salet, J. Roelofs, L. Akkermans, G. Van Berge-Henegouwen, and A. Smout. Compliance of the proximal stomach and dyspeptic symptoms in patients with type I diabetes mellitus. Dig. Dis. Sci. 40: 2037-2042, 1995.
40. Schvarcz, E., M. Palmer, J. Aman, M. Horowitz, M. Stridsberg, and C. Berne. Changes in blood glucose within the physiological range affect gastric emptying in normal subjects and patients with insulin dependent diabetes mellitus. Gastroenterology 113: 60-66, 1997.
41. Schvarcz, E., M. Palmer, J. Aman, B. Lindkvist, and K. W. Beckman. Hypoglycaemia increases the gastric emptying rate in patients with type I diabetes mellitus. Diabet. Med. 10: 660-663, 1993.
42. Schvarcz, E., M. Palmer, C. Ingberg, J. Aman, and C. Berne. Increased prevalence of upper gastrointestinal symptoms in long-term type 1 diabetes mellitus. Diabet. Med. 13: 478-481, 1996.
43. Sepple, C. P., and N. W. Read. Gastrointestinal correlates of the development of hunger in man. Appetite 13: 183-191, 1989.
44. Sims, M. A., W. L. Hasler, W. D. Chey, M. S. Kim, and C. Owyang. Hyperglycemia inhibits mechanoreceptor-mediated gastrocolonic responses and colonic peristaltic reflexes in healthy humans. Gastroenterology 108: 350-359, 1995.
45. Sun, W. M., S. Doran, T. Lingenfelser, G. S. Hebbard, J. E. Morley, J. Dent, and M. Horowitz. Effects of glyceryl trinitrate on the pyloric motor response to intraduodenal triglyceride infusion in humans. Eur. J. Clin. Invest. 26: 657-664, 1996.