Evaluation of C3a receptor expression on human leucocytes by the use of novel monoclonal antibodies

Immunology

Volumn 97, Issue 1, 1999, Pages 166-172

  Zwirner, J ^a   Gotze O ^a   Begemann, G ^b   Kapp, A ^b   Kirciihoff, K ^b   Werfel, T ^b  

^a UNIVERSITY OF GÖTTINGEN   (Germany)

^b HANNOVER MEDICAL SCHOOL   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENT COMPONENT C3A; COMPLEMENT COMPONENT C3B RECEPTOR; MONOCLONAL ANTIBODY;

ANIMAL CELL; ANTIGEN EXPRESSION; ARTICLE; BASOPHIL; CONTROLLED STUDY; EOSINOPHIL; HUMAN; HUMAN CELL; LEUKOCYTE ACTIVATION; MONOCYTE; NEUTROPHIL; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIGENS, CD; B-LYMPHOCYTES; BASOPHILS; EOSINOPHILS; FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT; HUMANS; LEUKOCYTES; MEMBRANE PROTEINS; MONOCYTES; NEUTROPHILS; RATS; RECEPTOR, ANAPHYLATOXIN C5A; RECEPTORS, COMPLEMENT; TUMOR CELLS, CULTURED;

EID: 0032941977     PISSN: 00192805     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2567.1999.00764.x     Document Type: Article

References (35)

1. 1. Ames R.S., Li Y., Sarau H.M. et al. (1996) Molecular cloning and characterization of the human anaphylatoxin C3a receptor. J Biol Chem 271, 20231.
2. 2. Crass T., Raffetseder U., Martin U. et al. (1996) Expression cloning of the human C3a anaphylatoxin receptor (C3aR) from differentiated U-937 cells. Eur J Immunol 26, 1944.
3. 3. Roglic A., Prossnitz E.R., Cavanagh S.L., Pan Z., Zou A. & Ye R.D. (1996) cDNA cloning of a novel G protein-coupled receptor with a large extracellular loop structure. Biochim Biophys Acta 1305, 39.
4. 4. Hugli T.E. (1989) Structure and function of C3a anaphylatoxin. Curr Top Microbiol Immunol 153, 181.
5. 5. Bischoff S.C., De Weck A.L. & Dahinden C.A. (1990) Interleukin 3 and granulocyte/macrophage-colony-stimulating factor render human basophils responsive to low concentrations of complement component C3a. Proc Natl Acad Sci USA 87, 6813.
6. 6. El-Lati S.G., Dahinden C.A. & Church M.K. (1994) Complement peptides C3a- and C5a-induced mediator release from dissociated human skin mast cells. J Invest Dermatol 102, 803.
7. 7. Kretschmar T., Jeromin A., Gietz C. et al. (1993) Chronic myelogenous leukemia-derived basophilic granulocytes express a functional active receptor for the anaphylatoxin C3a. Eur J Immunol 23, 558.
8. 8. Nilsson G., Johnell M., Hammer C.H. et al. (1996) C3a and C5a are chemotaxins for human mast cells and act through distinct receptors via a pertussis toxin-sensitive signal transduction pathway. J Immunol 157, 1693.
9. 9. Hartmann K., Henz B.M., Krüger-Krasagakes S. et al. (1997) C3a and C5a stimulate chemotaxis of human mast cells. Blood 89, 2863.
10. 10. Zwirner J., Götze O., Sieber A. et al. (1998) The human mast cell line HMC-1 binds and responds to C3a but not C3a (desArg). Scand J Immunol 47, 19.
11. 11. Elsner J., Oppermann M., Czech W. et al. (1994) C3a activates reactive oxygen radical species production and intracellular calcium transients in human eosinophils. Eur J Immunol 24, 518.
12. 12. Takafuji S., Tadokoro K. & Dahinden C.A. (1994) Degranulation from human eosinophils stimulated with C3a and C5a. Int Arch Allergy Appl Immunol 104, 27.
13. 13. Daffern P.J., Pfeifer P.H., Ember J.A. & Hugli T.E. (1995) C3a is a chemotaxin for human eosinophils but not for neutrophils. I. C3a Stimulation of neutrophils is secondary to eosinophil activation. J Exp Med 181, 2119.
14. 14. Elsner J., Oppermann M., Czwch W. & Kapp A. (1994) C3a activates the respiratory burst in human polymorphonuclear leukocytes via pertussis toxin-sensitive G-proteins. Blood 83, 3324.
15. 15. Zwirner J., Werfel T., Wilken H.-C., Theile E. & Götze O. (1998) Anaphylatoxin C3a but not C3a (desArg) is a chemotaxin for the mouse macrophage cell line J774. Eur J Immunol 28, 1570.
16. 16. Martin U., Bock D., Arseniev L. et al. (1997) The human C3a receptor is expressed on neutrophils and monocytes, but not on B or T lymphocytes. J Exp Med 186, 199.
17. 17. Hawlisch H., Frank R., Hennecke M. et al (1998) Site-directed C3a receptor antibodies from phage display libraries. J Immunol 160, 2947.
18. 18. Haeffner-Cavaillon N., Cavaillon J.M., Laude M. & Kazatchkine M.D. (1987) C3a (C3a des-Arg) induces production and release of interleukin 1 by cultured human monocytes. J Immunol 139, 794.
19. 19. Takabayashi T., Vannier E., Clark B.D. et al. (1996) A new biologic role for C3a and C3a des Arg. J Immunol 156, 3455.
20. 20. Takabayashi T., Vannier E., Burke J.F., Tompkins R.G., Gelfand J.A. & Clark B.D. (1998) Both C3a and C3a (desArg) regulate interleukin-6 synthesis in human peripheral blood mononuclear cells. J Infect Dis 177, 1622.
21. 21.Zwirner J., Götze O., Moser A. et al. (1997) Blood-and skin-derived monocytes/macrophages respond to C3a but not to C3a (desArg) with a transient release of calcium via a pertussis toxin-sensitive signal transduction pathway. Eur J Immunol 27, 2317.
22. desArg. J Immunol 159, 4279.
23. 23. Rothermel E., Zwirner J., Vogt T., Rabini S. & Götze O. (1997) Molecular cloning and expression of the functional rat C5a receptor. Mol Immunol 34, 877.
24. 24. Butterfield J.H., Weiler D., Dewald G. & Gleich G.J. (1988) Establishment of an immature mast cell line from a patient with mast cell leukemia. Leuk Res 12, 345.
25. 25. Werfel T., Oppermann M., Schulz M., Krieger G., Weber M. & Götze O. (1992) Binding of fluorescein-labeled anaphylatoxin C5a to human peripheral blood, spleen, and bone marrow leukocytes. Blood 79, 152.
26. 26. Oppermann M., Raedi U., Hebell T. & Götze O. (1993) Probing the human receptor for C5a anaphylatoxin with site directed antibodies. Identification of a potential ligand binding site on the NH2-terminal domain. J Immunol 74, 3785.
27. 27. Lavabre-Bertrand T., Duperray C., Brunet C. et al. (1994) Quantification of CD24 and CD45 antigens in parallel allows a precise determination of B-cell maturation stages: relevance for the study of B-cell neoplasias. Leukemia 8, 402.
28. 28. Poncelelt P. & Carayon P. (1985) Cytofluorometric quantification of cell-surface antigens by indirect immunofluorescence using monoclonal antibodies. J Immunol Methods 85, 65.
29. 29. Legler D.F., Loetscher M., Jones S.A., Dahinden C.A., Arock M. & Moser B. (1996) Expression of high- and low-affinity receptors for C3a on the human mast cell line HMC-1. Eur J Immunol 26, 753.
30. 30. Klotz I.M. (1982) Numbers of receptor sites from Scatchard graphs: facts and fantasies. Science 217, 1247.
31. 31. Werfel T., Oppermann M., Butterfield J.H. et al. (1996) The human mast cell line HMC-1 expresses C5a receptors and responds to C5a but not to C5a (desArg). Scand J Immunol 44, 30.
32. 3 and all-trans retinoic acid. Eur J Immunol 27, 935.
33. 33. Glovsky M.M., Hugli T.E., Ishizaka T., Lichtenstein L.M. & Erickson B.W. (1979) Anaphylatoxin-induced histamine release with human leukocytes. Studies of C3a leukocyte binding and histamine release. J Clin Invest 64, 804.
34. 125I-C3a binding. Biochemistry 31, 11274.
35. 35. Gerardy-Schahn R., Ambrosius D., Saunders D. et al. (1989) Characterization of C3a receptor-protein on guinea pig platelets and human polymorphonuclear leukocytes. Eur J Immunol 19, 1095.