Dose response with fluticasone propionate on adrenocortical activity and recovery of basal and stimulated responses after stopping treatment

Clinical Endocrinology

Volumn 50, Issue 3, 1999, Pages 329-335

  Wilson, Andrew M ^a   Sims, Erika J ^a   Lipworth, Brian J ^a  

^a UNIVERSITY OF DUNDEE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BECLOMETASONE DIPROPIONATE; BUDESONIDE; CORTICOTROPIN; CORTICOTROPIN RELEASING FACTOR; FLUTICASONE PROPIONATE; HYDROCORTISONE; OSTEOCALCIN;

ADRENAL CORTEX FUNCTION; ADRENAL SUPPRESSION; ADULT; ARTICLE; ASTHMA; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOSE RESPONSE; DRUG MEGADOSE; FEMALE; FORCED EXPIRATORY VOLUME; HUMAN; HUMAN CELL; HUMAN TISSUE; MALE; METERED DOSE INHALER; PRIORITY JOURNAL; SINGLE BLIND PROCEDURE; STEROID THERAPY; URINARY EXCRETION;

ADRENAL CORTEX; ADULT; ANDROSTADIENES; ANTI-ASTHMATIC AGENTS; ASTHMA; CORTICOTROPIN-RELEASING HORMONE; CREATININE; DEPRESSION, CHEMICAL; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; HUMANS; HYDROCORTISONE; MALE; OSTEOCALCIN; SINGLE-BLIND METHOD;

EID: 0032941189     PISSN: 03000664     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2265.1999.00652.x     Document Type: Article

References (27)

1. American College of Rheumatology Task Force on Osteoporosis Guidelines (1996) Recommendations for the prevention and treatment of glucocorticoid-induced osteoporosis. Arthritis and Rheumatism, 39, 1791-1801.
2. American Thoracic Society (1987) Standards for the diagnosis and care of patients with chronic obstructive pulmonary disease (COPD) and asthma. American Review of Respiratory Disease, 136, 225-243.
3. Bikle, D.D. (1997) Biochemical markers in the assessment of bone disease. American Journal of Medicine, 103, 427-436.
4. Boorsma, M., Anderson, N., Larsson, P. & Ullman, A. (1996) Assessment of the relative systemic potency ofhaled fluticasone and budesonide. European Respiratory Journal, 9, 1427-1432.
5. British guidelines on asthma management (1997) 1995 review and position statement. Thorax, 52 (Suppl. 1), S 1-S28.
6. Broide, J., Soferman, R., Kivity, S., Golander, A., Dickstein, G., Spirer, Z. & Weisman, Y. (1995) Low-dose adrenocorticotropin test reveals impaired adrenal function in patients taking inhaled corticosteroids. Journal of Clinical Endocrinology and Metabolism, 80, 1243-1246.
7. Brown, P.H., Blundell, G., Greening, A.P. & Crompton, G.K. (1991) Screening for hypothalamo-pituitary-adrenal axis suppression in asthmatics taking high dose inhaled corticosteroids. Respiratory Medicine, 85, 511-516.
8. Clark, D.J. & Lipworth, B.J. (1997a) Adrenal suppression with chronic-dosing of fluticasone propionate compared with budesonide in adult asthmatic patients. Thorax, 52, 55-58.
9. Clark, D.J. & Lipworth, B.J. (1997b) Evaluation of corticotropin releasing factor stimulation and basal markers of hypothalamic-pituitary-adrenal axis suppression in asthmatic patients. Chest, 112, 1248-1252.
10. Committee of Safety of Medicines (1997) Using long-term systemic corticosteroids safely. Current Problems in Pharmacovigilance, 23, 1-4.
11. Donnelly, R., Williams, K.M., Baker, B., Badcock, C.A., Day, R.O. & Seale, P. (1997) Effects of budesonide and fluticasone propionate on 24 hour plasma cortisol. American Journal of Respiratory and Critical Care Medicine, 156, 1748-1751.
12. Grebe, S.K.G., Peek, C.M., Durham, J.A., Kljakovic, M. & Cooke, R.R. (1997) Inhaled beclomethasone dipropionate suppresses the hypothalmo-pituitary-adrenal axis in a dose-dependent manor. Clinical Endocrinology, 47, 297-304.
13. Honour, J.W. (1994) Hypothalamic-pituitary-adrenal axis. Respiratory Medicine, 88 (Suppl. A) , 9-15.
14. Knuttson, U., Stierna, P., Marcus, C., Carlstedt-Duke, J., Carlstrom, K. & Bronnegard, M. (1995) Effects oftranasal glucocorticoids on endogenous glucocorticoid peripheral and central function. Journal of Endocrinology, 144, 301-310.
15. Lipworth, B.J. (1996) Airway and systemic effects ofhaled corticosteroids in asthma: dose response relationship. Pulmonary Pharmacology, 9, 19-27.
16. Lipworth, B.J. & Seekl, J.R. (1997) Measures for detecting systemic bioactivity with inhaled and intra-nasal corticosteroids. Thorax, 52, 476-582.
17. Livanou, T., Ferriman, D. & James, V.H.T. (1967) Recovery of hypothalamo-pituitary adrenal function after corticosteroid therapy. Lancet, 2, 856-859.
18. National Asthma Education and Prevention Programme (1997) Expert Panel Report II: Guidelines for the Diagnosis and Management of Asthma. Publication no. 97-4051, National Institutes of Health, Bethesda, MD.
19. Salem, M., Tainsh, R.E., Bromberg, J., Loriaux, D.L. & Chernow, B. (1994) Perioperative glucocorticoid coverage. A reassessment 42 years after emergence of a problem. Annals of Surgery, 219, 416-425.
20. Schlanghecke, R., Kornely, E., Santen, R.T. & Ridderskamp, P. (1992) The effect of long term glucocorticoid therapy on pituitary-adrenal responses to exogenous corticotropin releasing hormone. New England Journal of Medicine, 326, 226-236.
21. Thorsson, L., Dahlstrom, K., Edshacker, S., Kallen, A., Paulson, J. & Wiren, J.E. (1997) Pharmacokinetics and systemic effects of fluticasone propionate in healthy subjects. British Journal of Clinical Pharmacology, 43, 155-161.
22. Toogood, J.H., Baskerville, J., Jennings, B.A., Lefcoe, N.M. & Johansson, S.A. (1989) Bioequivalent doses of budesonide and prednisone in moderate and severe asthma. Journal of Allergy and Clinical Immunology, 84, 688-700.
23. Wasnich, R. (1993) Bone mass measurement: prediction of risk. American Journal of Medicine, 95 (Suppl. 5A), 65-105.
24. Webb, J. & Clark, J.H. (1981) Recovery of plasma corticotropin and cortisol levels after a three-week course of prednisolone. Thorax, 36, 22-24.
25. Wilson, A.M. & Lipworth, BJ. (1997) Systemic dose-response relationships with oral and inhaled corticosteroids in asthmatics. Thorax, 52 (Suppl. 6), A57.
26. Wong, J. & Black, P. (1992) Acute adrenal insufficiency associated with high dose inhaled steroids. British Medical Journal, 304, 1415.
27. Zwaan, C.M., Odink, R.J.H., Delemarre-Van de Waal, H.A., Dankert-Roelse, J.E., & Bokma J.A. (1992) Acute adrenal insufficiency after discontinuation ofhaled corticosteroid therapy. Lancet, 340, 1289-1290.