Recommendations for the prevention and treatment of glucocorticoid- induced osteoporosis

Arthritis and Rheumatism

Volumn 39, Issue 11, 1996, Pages 1791-1801

  Hochberg, Marc C ^a   Prashker, Mark J ^b   Greenwald, Maria ^c   Mirage, Rancho ^c   Hannan, Marian T ^c   Lane, Nancy E ^d   Lindsey, Stephen M ^e   Lovell, Daniel J ^f   Tindall, Elizabeth A ^g  

^a UNIVERSITY OF MARYLAND   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

^c BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e OCHSNER MEDICAL CENTER   (United States)

^f CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

^g NONE

Author keywords

[No Author keywords available]

Indexed keywords

ALENDRONIC ACID; ANABOLIC AGENT; BISPHOSPHONIC ACID DERIVATIVE; CALCITONIN; CALCIUM; ETIDRONIC ACID; FLUORIDE; GLUCOCORTICOID; PREDNISONE; SEX HORMONE; THIAZIDE DIURETIC AGENT; VITAMIN D;

ALCOHOL CONSUMPTION; ANALGESIA; BONE DENSITY; BONE MALFORMATION; BONE MINERAL; CALCIUM HOMEOSTASIS; COMPUTER ASSISTED TOMOGRAPHY; DOSE TIME EFFECT RELATION; EXERCISE; HORMONE SUBSTITUTION; HUMAN; MUSCLE WEAKNESS; MYOPATHY; OSTEOLYSIS; OSTEOPOROSIS; PATHOLOGIC FRACTURE; PRIORITY JOURNAL; REVIEW; SMOKING CESSATION; STEROID THERAPY;

GLUCOCORTICOIDS; HUMANS; OSTEOPOROSIS;

EID: 0029864560     PISSN: 00043591     EISSN: None     Source Type: Journal    
DOI: 10.1002/art.1780391104     Document Type: Review

References (87)

1. Mitchell DR, Lyles KW: Glucocorticoid-induced osteoporosis: mechanisms for bone loss; evaluation of strategies for prevention. J Gerontol 45:M153-M155, 1990
2. Lukert BP, Raisz LG: Glucocorticoid-induced osteoporosis: pathogenesis and management. Ann Intern Med 112:352-364, 1990
3. Smith R: Corticosteroids and osteoporusis. Thorax 45:573-578, 1990
4. Lihanati CR, Baylink DJ: Prevention and treatment of glucocorticoid-induced osteoporosis: a pathogenetic perspective. Chest 102:1426-1435, 1992
5. Adachi JD, Bensen WG, Hodsman AB: Corticosteroid-induced osteoporosis. Semin Arthritis Rheum 22:375-384, 1993
6. Hahn TJ: Steroid and drug induced osteoporosis. In, Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism. Second edition. Edited by MJ Favus. New York, Raven Press, 1993
7. Olbricht T, Benker G: Glucocorticoid-induced osteoporosis: pathogenesis, prevention and treatment, with special regard to the rheumatic diseases. J Intern Med 234:237-244, 1993
8. Reid IR, Grey AB: Corticosteroid osteoporosis. Baillieres Clin Rheumatol 7:573-587, 1993
9. Lukert BP, Raisz LG: Glucocorticoid-induced osteoporosis. Rheum Dis Clin North Am 20:630-651, 1994
10. Joseph JC: Corticosteroid-induced osteoporosis. Am J Hosp Pharm 51:188-197, 1994
11. Sambrook PN, Jones G: Corticosteroid osteoporosis. Br J Rheumatol 34:8-12, 1995
12. Eastell R on behalf of a UK Consensus Group Meeting on Osteoporosis: Management of corticosteroid-induced osteoporosis. J Intern Med 237:439-447, 1995
13. Lane NE, Mroczkowski PJ, Hochberg MC: Prevention and management of glucocorticoid-induced osteoporosis. Bull Rheum Dis 44:1-4, 1995
14. Dequeker J, Westhovens R: Low dose corticosteroid associated osteoporosis in rheumatoid arthritis and its prophylaxis and treatment: bones of contention. J Rheumatol 22:1013-1019, 1995
15. Hahn BH: Glucocorticoid-induced osteoporosis. Hosp Pract 45-56, 1995
16. Gulko PS, Mulloy AL: Glucocorticoid-induced osteoporosis: pathogenesis, prevention and treatment. Clin Exp Rheumatol 14:199-206, 1996
17. Adinoff AD, Hollister JR: Steroid-induced fractures and bone loss in patients with asthma. N Engl J Med 309:265-268, 1983
18. Verstraeten A, Dequeker J: Vertebral and peripheral bone mineral content and fracture evidence in postmenopausal patients with rheumatoid arthritis: effect of low dose corticosteroids. Ann Rheum Dis 45:852-857, 1986.
19. Dykman TR, Gluck OS, Murphy WA, Hahn TJ, Hahn BH: Evaluation of factors associated with glucocorticoid-induced osteopenia in patients with rheumatic diseases. Arthritis Rheum 28: 361-368, 1985
20. Michel BA, Bloch DA, Fries JF: Predictors of fractures in early rheumatoid arthritis. J Rheumatol 18:804-808, 1991
21. Michel BA, Bloch PA, Wolfe F, Fries JF: Fractures in rheumatoid arthritis: an evaluation of associated risk factors. J Rheumatol 20:1666-1669, 1993
22. Cooper C, Coupland C, Mitchell M: Rheumatoid arthritis, corticosteroid therapy and hip fracture. Ann Rheum Dis 54:49-52, 1994
23. Saag KG, Koehnke R, Caldwell JR, Brasington R, Burmeister LF, Zimmerman B, Kohler JA, Furst DE: Low dose long-term corticosteroid therapy in rheumatoid arthritis: an analysis of serious adverse events. Am J Med 96:115-123, 1994
24. Marystone JF, Barrett-Connor EL, Morton DJ: Inhaled and oral corticosteroids: their effect on bone mineral density in older adults. Am J Public Health 85:1693-1695, 1995
25. Gluck OS, Murphy WA, Hahn TJ, Hahn BH: Bone loss in adults receiving alternate day glucocorticoid therapy: a comparison with daily therapy. Arthritis Rheum 24:892-898, 1981
26. Ruegsegger P, Medici TC, Anliker M: Corticosteroid-induced bone loss: a longitudinal study of alternate day therapy in patients with bronchial asthma using quantitative computed tomography. Eur J Clin Pharmacol 25:615-620, 1994
27. Ward MJ: Inhaled corticosteroids - effect on bone? Respir Med 87 (suppl A):33-36, 1993
28. Boyd G: Effect of inhaled corticosteroids on bone. Respir Med 88 (suppl A):45-54, 1994
29. Hanania NA, Chapman KR, Sturtridge WC, Szalai JP, Kesten S: Dose-related decrease in bone density among asthmatic patients treated with inhaled corticosteroids. J Allergy Clin Immunol 96:571-579, 1995
30. Klein RG, Arnaud SB, Gallagher JC, Deluca HF, Riggs BL: Intestinal calcium absorption in exogenous hypercortisolism: role of 25-hydroxyvitamin D and corticosteroid dose. J Clin Invest 64:655-665, 1977
31. Hahn TJ, Halstead LR, Teitelbaum SL, Hahn BH: Altered mineral metabolism in glucocorticoid-induced osteopenia: effect of 25-hydroxy vitamin D administration. J Clin Invest 64:655-665, 1979
32. Suzuki Y, Ichikawa Y, Saito E, Homma M: Importance of increased urinary calcium excretion in the development of secondary hyperparathyroidism of patients under glucocorticoid therapy. Metabolism 32:151-156, 1983
33. Brandli DW, Golde G, Greenwald M, Silverman SL: Glucocorticoid-induced osteoporosis: a cross-sectional study. Steroids 56:518-523, 1991
34. Seeman E, Kumar R, Huder GG, Scott M, Heath H, Riggs BL: Production, degradation and circulating levels of 1,25-dihydroxy vitamin D in health and in chronic glucocorticoid excess. J Clin Invest 66:664-669, 1980
35. Hsueh AJ, Erickson GF: Glucocorticoid inhibition of FSH-induced estrogen production in cultured rat granulosa cells. Steroids 32:639-648, 1978
36. MacAdams MR, White RH, Chipps BE: Reduction in serum testosterone levels during chronic glucocorticoid therapy. Ann Intern Med 104:648-651, 1986
37. Reid IR, France JT, Pybus J, Ibbertson HK: Low plasma testosterone levels in glucocorticoid-treated male asthmatics. BMJ 291:574-578, 1985
38. Dempster DW, Arlot MA, Meunier PI: Mean wall thickness and formation periods of trabecular bone packets in corticosteroid-induced osteoporosis. Calcif Tissue Int 35:410-417, 1983
39. Gronowicz G, McCarthy MB: Glucocorticoids inhibit the attachment of osteoblasts to bone extracellular matrix proteins and decreases β-1 integrin levels. Endocrinology 136:598-608, 1995
40. Hughes-Fulford M, Blaug S: Down regulation of c-fos and cell growth with upregulation of p53 oncogene in glucocorticoid treated osteoblasts (abstract). J Bone Miner Res 8:S365, 1993
41. Canalis EM: Effect of glucocorticoids on type I collagen synthesis, alkaline phosphatase activity, and deoxyribonucleic acid content in cultured rat calvariae. Endocrinology 112:931-939, 1983
42. Jonsson KB, Ljunghall S, Karlstrom O, Johansson AG, Mallmain H, Ljunggren O: Insulin-like growth factor I enhances the formation of type I collagen in hydrocortisone-treated human osteoblasts. Biosci Rep 13:297-302, 1993
43. Centrella M, McCarthy TL, Canalis E: Glucocorticoid control of transforming growth factor β activity and binding and effects in osteoblast-enriched cultures from fetal rat bone. Mol Cell Biol 11:4490-4496, 1991
44. Genant HK, Engelke K, Fuerst T, Gluer CC, Grampp S, Harris ST, Jergas M, Lang T, Lu Y, Majumdar S, Mathur A, Takada M: Noninvasive assessment of bone mineral and structure: state of the art. J Bone Miner Res 11:707-730, 1996
45. Miller PD, Bonnick SL, Rosen CJ, for the Society for Clinical Densitometry: Clinical utility of bone mass measurement in adults: consensus of an international panel. Semin Arthritis Rheum 25:361-372, 1996
46. Johnston CC Jr, Melton LJ III, Lindsay R, Eddy DM: Clinical indications for hone mass measurements: a report from the Scientific Advisory Board of the National Osteoporosis Foundation. J Bone Miner Res 4 (suppl 2):1-28, 1989
47. Yu W, Gluer CC, Fuerst T, Grampp S, Li J, Lu Y, Genant HK: Influence of degenerative joint disease on spinal bone mineral measurements in postmenopausal women. Calcif Tissue Int 57: 169-174, 1995
48. Lufkin EG, Wahner HW, Bergstralh EJ: Reversibility of steroid-induced osteoporosis. Am J Med 85:887-888, 1988
49. Reid IR, Ibbertson HK: Calcium supplements in the prevention of steroid-induced osteoporosis. Am J Clin Nutr 44:287-290, 1986
50. Hahn TJ, Hahn BH: Osteopenia in patients with rheumatic diseases: principles of diagnosis and therapy. Semin Arthritis Rheum 6:165-188, 1976
51. Adachi JD, Bensen WG, Bianehi F, Cividino A, Pillersdorf S, Sebaldt RJ, Tugwell P, Gordon M, Steele M, Webber C, Goldsmith CH: Vitamin D and calcium in the prevention of corticosteroid induced osteoporosis: a 3 year followup. J Rheumatol 23:995-1000, 1996
52. Sambrook P, Birmingham J, Kelly P, Kempler S, Nguyen T, Pocock N, Eisman J: Prevention of corticosteroid osteoporosis: a comparison of calcium, calcitriol, and calcitonin. N Engl J Med 328:1747-1752, 1993
53. Adams JS, Wahl TO, Lukert BP: Effects of hydrochlorothiazide and dietary sodium restriction on calcium metabolism in corticosteroid treated patients. Metabolism 30:217-221, 1981
54. Cauley JA, Cummings SR, Seelcy DG, Black D, Browner W, Kuller LH, Nevitt MC: Effects of thiazide diuretic therapy on bone mass, fractures and falls: The Study of Osteoporotic Fractures Research Group. Ann Intern Med 118:666-673, 1993
55. Morton DJ, Barrett-Connor EL, Edelstein SL: Thiazides and bone mineral density in elderly men and women. Am J Epidemiol 139:1107-1115, 1994
56. Jones G, Nguyen T, Sambrook PH, Eisman JA: Thiazide diuretics and fractures: can mcta-analysis help? J Bone Miner Res 10:106-111, 1995
57. Lukert BP, Johnson BE, Robinson RG: Estrogen and progesterone replacement therapy reduces glucocorticoid-induced hone loss. J Bone Miner Res 7:1063-1069, 1992
58. Hall GM, Daniels M, Doyle DV, Spector TD: Effect of hormone replacement therapy on bone mass in rheumatoid arthritis patients treated with and without steroids. Arthritis Rheum 37:1499-1505, 1994
59. Sowers MFR, Galuska DA: Epidemiology of bone mass in premenopausal women. Epidemiol Rev 15:374-398, 1993
60. Reid IR, Wattie DJ, Evans MC, Stapleton JP: Testosterone therapy in glucocorticoid-treated men. Arch Intern Med 156:1173-1177, 1996
61. Bagatell CJ, Bremner WJ: Androgens in men - uses and abuses. N Engl J Med 334:707-714, 1996
62. Rodan GA, Fleisch HA: Bisphosphonates: mechanisms of action. J Clin Invest 97:2692-2696, 1996
63. Mulder H, Struys A: Intermittent cyclical etidronate in the prevention of corticosteroid-induced bone loss. Br J Rheumatol 33:348-350, 1994
64. Diamond T, McGuigan L, Barbagallo S, Bryant C: Cyclical etidronate plus ergocalciferol prevents glucocorticoid-induced bone loss in postmenopausal women. Am J Med 98:459-463, 1995
65. Adachi JD, Cranney A, Goldsmith CH, Bensen WG, Bianehi F, Cividino A, Craig GL, Kaminska E, Sebaldt RJ, Papaioannou A, Boratto M, Gordon M, Steele M: Intermittent cyclic therapy with etidronate in the prevention of corticosteroid induced bone loss. J Rheumatol 21:1922-1926, 1994
66. Struys A, Snelder AA, Mulder H: Cyclical etidronate reverses bone loss of the spine and proximal femur in patients with established corticosteroid-induced osteoporosis. Am J Med 99: 235-242, 1995
67. Reid IR, King AR, Alexander CJ, Ibbertson HK: Prevention of steroid-induced osteoporosis with (3-amino-1-hydroxypropylidene)-1,1-bisphosphonate (APD). Lancet 1:143-146, 1988
68. Reid IR, Heap SW, King AR, lbbertson HK: Two-year followup of biphosphonate (APD) treatment in steroid osteoporosis. Lancet 2:1144-1145, 1488
69. Ringe JD, Welzel D: Salmon calcitonin in the therapy of corticosteroid-induced osteoporosis. Eur J Clin Pharmacol 33:35-39, 1987
70. Montcmorro L, Schiraldi G, Fraioli P, Tosi G, Rihddi A, Rizzato G: Prevention of corticosteroid-induced osteoporosis with salmon calcitonin in sarcoid patients. Calcif Tissue Int 49:71-76, 1991
71. Healey J. Paget S, Williams-Russo P, Szatrowski T, Schneider R, Spiera H, Mitnick H, Ales K, Schwartzberg P: Randomized trial of salmon calcitonin to prevent hone loss in corticosteroid-treated temporal arteritis and polymyalgia rheumatica. Calcif Tissue Int 58:73-80, 1996
72. Adami S, Rossini M: Anabolic steroids in corticosteroid-induced osteoporosis. Wien Med Wochenschr 44:395-397, 1993
73. Greenwald M, Brandli D, Spector S, Silverman S, Golde G: Corticosteroid-induced osteoporosis: effects of a treatment with slow-release sodium fluoride. Osteoporosis Int 2:203-204, 1992
74. Tinetti ME: Performance-oriented assessment of mobility problems in elderly patients. J Am Geriatr Soc 34:119-126, 1986
75. Rubenstein LZ, Robbins AS, Josephson KR, Schulman BL, Osterweil D: The value of assessing falls in an elderly population. Ann Intern Med 113:308-316, 1990
76. Pun KK, Chan LWL: Analgesic effect of intranasal salmon calcitonin in the treatment of osteoporotic vertebral fractures. Clin Ther 11:205-209, 1989
77. Sinaki M: Musculoskeletal rehabilitation. In, Osteoporosis: Etiology, Diagnosis, and Management. Second edition. Edited by BL Riggs, LJ Melton III. Philadelphia, Lippincott-Ravcn, 1995
78. Simkin A, Ayalon J, Leichter I: Increased trabecular bone density due to bone-loading exercises in postmenopausal osteoporotic women. Calcif Tissue Int 40:59-63, 1987
79. Dalsky GP, Stocke KS, Ehsani AA, Slatopolsky E, Lee WC, Birge SJ: Weight-bearing exercise training and lumbar bone mineral content in postmenopausal women. Ann Intern Med 108:824-828, 1988
80. Rubin S, Cummings S: Results of bone densitometry affect women's decisions. Ann Intern Med 116:990-995, 1992
81. Slemenda CW, Reister TK, Hui SL, Miller JZX, Christian JC, Johnston CC: Influences on skeletal mineralization in children and adolescents: evidence for varying effects of sexual maturation and physical activity. J Pediatr 125:201-207, 1994
82. Kreipe RE: Bones of today, hones of tomorrow. Am J Dis Child 146:22-25, 1992
83. Thomas KA, Cook SD, Bennett JT: Femoral neck and lumbar spine bone mineral densities in a normal population 3-20 years of age. J Pediatr Orthop 11:48-58, 1991
84. Warady BD, Lindsley CB, Robinson RG, Lukert BP: Effects of nutritional supplementation on bone mineral status of children with rheumatic diseases receiving corticosteroid therapy. J Rheumatol 21:530-535, 1994
85. NIH Consensus Development Panel on Optimal Calcium Intake: Optimal calcium intake. JAMA 272:1942-1947, 1994
86. Alien DB, Goldbcrg BD: Stimulation of collagen synthesis and linear growth by growth hormone in glucocorticoid-treated children. Pediatrics 89:416-421, 1984
87. Taylor AK, Leuken SA, Libanati C, Baylink DJ: Biochemical markers of bone turnover for the clinical assessment of bone metabolism. Rheum Dis Clin North Am 20:589-607, 1994