PTEN/MMAC1 mutations in hepatocellular carcinomas: Somatic inactivation of both alleles in tumors

Japanese Journal of Cancer Research

Volumn 90, Issue 4, 1999, Pages 413-418

  Kawamura, Naoki ^a,b   Nagai, Hisaki ^a   Bando, Koichi ^a   Koyama, Masaaki ^a   Matsumoto, Satoshi ^a   Tajiri, Takashi ^a   Onda, Masahiko ^a   Fujimoto, Jiro ^c   Ueki, Takahiro ^c   Konishi, Noboru ^d   Shiba, Tadayoshi ^b   Emi, Mitsuru ^a  

^a NIPPON MEDICAL SCHOOL   (Japan)

^b KITASATO UNIVERSITY   (Japan)

^c HYOGO COLLEGE OF MEDICINE   (Japan)

^d NARA MEDICAL UNIVERSITY   (Japan)

Author keywords

Hepatocellular carcinoma; Loss of heterozygosity; PTEN MMAC1; Somatic mutation; Tumor suppressor gene

Indexed keywords

ALLELE; ARTICLE; CHROMOSOME 10Q; CODON; DELETION MUTANT; EXON; FRAMESHIFT MUTATION; GENE INACTIVATION; GENE LOSS; GENETIC MARKER; GENETIC POLYMORPHISM; HUMAN; HUMAN TISSUE; LIVER CARCINOGENESIS; LIVER CELL CARCINOMA; MAJOR CLINICAL STUDY; NUCLEIC ACID BASE SUBSTITUTION; POINT MUTATION; PRIORITY JOURNAL; SOMATIC MUTATION; TUMOR SUPPRESSOR GENE;

EID: 0032938982     PISSN: 09105050     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1349-7006.1999.tb00763.x     Document Type: Article

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