Water maze performance is unaffected in artificially reared rats fed diets supplemented with arachidonic acid and docosahexaenoic acid

Journal of Nutrition

Volumn 129, Issue 5, 1999, Pages 1079-1089

  Wainwright, P E ^a   Xing, H C ^a   Ward, G R ^a   Huang, Y S ^b   Bobik, E ^b   Auestad, N ^b   Montalto, M ^b  

^a UNIVERSITY OF WATERLOO   (Canada)

^b ABBOTT LABORATORIES   (United States)

Author keywords

Arachidonic acid; Brain development; Docosahexaenoic acid; Rat; Water maze learning

Indexed keywords

ARACHIDONIC ACID; DOCOSAHEXAENOIC ACID; LINOLEIC ACID; LINOLENIC ACID;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN DEVELOPMENT; BRAIN LEVEL; CONTROLLED STUDY; DIETARY INTAKE; LEARNING; LIPID COMPOSITION; MALE; NONHUMAN; PERFORMANCE; RAT; WORKING MEMORY;

EID: 0032938292     PISSN: 00223166     EISSN: None     Source Type: Journal    
DOI: 10.1093/jn/129.5.1079     Document Type: Article

References (45)

1. Agostini, C., Trojan, S., Bellu, R., Riva E., Bruzzese, M. G. & Giovannini, M. (1997) Developmental quotient at 24 months and fatty acid composition of diet in early infancy: a follow up study. Arch. Dis. Child. 76: 421-424.
2. Agostoni, C., Trojan, S., Bellu, R., Riva, E. & Giovannini, M. (1995) Neuradevelopmental quotient of healthy term infants at 4 mos. and feeding practice: the role of long-chain polyunsaturated fatty acids. Pedatr. Res. 38: 262-266.
3. Agid, Y., Javoy-Agid, F. & Ruberg, M. (1987) Biochemistry of neurotransmitters in Parkinson's disease. Mov. Disord. 2: 166-230.
4. Auestad, N., Montalto, M. B., Hall, R. T., Fitzgerald, K. M., Wheeler. R. E., Connor, W. E., Neuringer, M., Connor, S. L., Taylor, J. A. & Hartmann, E. E. (1997) Visual acuity, erythrocyte fatty acid composition, and growth in term infants fed formulas with long chain polyunsaturated fatty acids for one year. Ross Pediatric Upid Study. Pediatr. Res. 41: 1-10.
5. Birch, E. E., Birch, D. G., Hoffman, D. R. & Uauy, R. (1992) Dietary essential fatty acid supply and visual acuity development. Invest. Opthalmol. Vis. Sci. 33: 3242-3253.
6. Birch, E. E., Hoffman, D. R., Uauy, R., Birch, D. G. & Prestidge, C. (1998) Visual acuity and the essentiality of docosahexaenoic acid and arachidonic acid in the diet of term infants. Pediatr. Res. 44: 201-209.
7. Carlson, S. E., Cooke, R. J., Werkman, S. H. & Tolley, E. A. (1992) First year growth of preterm infants fed standard compared to marine oil (n-3) supplemented formula. Lipids 27: 901-907.
8. Carlson, S. E. & Werkman, S. H. (1996) A randomized trial of visual attention of preterm infants fed docosahexaenoic acid until two months. Lipids 31: 85-90.
9. Carlson, S. E., Werkman, S. H., Peoples, J. M., Cooke, R. J. & Tolley, E. A. (1993a) Arachidonic acid staus correlates with first year growth in preterm infants. Proc. Natl. Acad. Sci. U.S.A. 90: 1073-1077.
10. Carlson, S. E., Werkman, S. H., Peeples, J. M., Cooke, R. J. & Tolley, E. A. (1994) Growth and development of premature infants in relation to omega 3 and omega 6 fatty acid status. World Rev. Nutr. Diet 75: 3-69.
11. Carlson, S., Werkman, S. H., Rhodes, P. G. & Tolley, E. A. (1993b) Visual acuity development in healthy preterm infants: effects of marine oil supplementation. Am. J. Clin. Nutr. 58: 35-42.
12. Carlson, S. E., Werkman, S. H. & Tolley, E. A. (1996) Effect of long-chain (n-3) fatty acid supplementation on visual acuity and growth of preterm infants with and without bronchopulmonary dysplasia. Am. J. Clin. Nutr. 63: 687-697.
13. Connor, W. E., Neuringer, M. & Reisbick, S. (1992) Essential fatty acids: the importance of n-3 fatty acids in the retina and brain. Nutr. Rev. 50: 21-29.
14. Cook, H. W. (1991) Fatty acid desaturation and chain elongation in eucaryotes. In: Biochemistry of Lipids, Lipoproteins and Membranes (Vance, D. E. & Vance, J., eds.), pp. 141-169. Elsevier, Amsterdam, The Netherlands.
15. Delion S., Chalon, S., Herault, J., Guilloteau, D., Besnard, J.-C. & Durand, G. (1994) Chronic dietary α-linolenic acid deficiency alters dopaminergic and serotoninergic neurotransmission in rats. J. Nutr. 124: 2466-2476.
16. Dobbing, J., ed. (1997) Developing Brain and Behavior: The Role of Lipids in Infant Formula. Academic Press, London, England.
17. Everitt, B. J. & Robbins, T. W. (1997) Central cholinergic systems and cognition. Annu. Rev. Psychol. 48: 649-684.
18. Folch, J., Lees, M. & Sloane-Stanley, G. H. (1957) A simple method for the isolation and purification of total lipids from animal tissues. J. Biol. Chem. 226: 497-509.
19. Galli, C., Trzeciak, J. B. & Paoletti, R. (1971) Effects of dietary fatty acids on the fatty acid composition of brain ethanolamine phosphoglyceride: reciprocal replacement of n-6 and n-3 polyunsaturated fatty acids. Biochim. Biophys. Acta 248: 449-454.
20. Greenwood, C. E. & Winocur, G. (1996) Cognitive impairment in rats fed high fat diets: a specific effect of saturated fatty acid intake. Behav. Neurosci. 110: 451-459.
21. Innis, S. (1991) Essential fatty acids in growth and development. Prog. Lipid Res. 30: 39-103.
22. Makrides, M., Neumann, M. A. & Gibson, R. A. (1996) Is dietary docosahexaenoic acid essential for term infants? Lipids 31: 115-119.
23. Mohrhauer, H. & Holman, R. T. (1963) Alteration of the fatty acid composition of brain lipids by varying levels of dietary essential fatty acids. J. Neurochem. 10: 523-530.
24. Morrison, W. R. & Smith, L. M. (1964) Preparation of fatty acid methyl esters and dimethylacetals from lipids with boron trifluoride-methanol. J. Lipid Res. 5: 600-608.
25. Reeves, P. G., Nielsen, F. H. & Fahey, G. C., Jr. (1993) AIN-93 purified diets for laboratory rodents: final report of the American Institute of Nutrition ad hoc writing committee on the reformulation of the AIN-76A rodent diet. J. Nutr. 123: 1939-1951.
26. Reisbick, S. & Neuringer, M. (1997) Omega-3 fatty acid deficiency and behavior: a critical review and directions for future research. In: Handbook of Essential Fatty Acid Biology: Biochemistry, Physiology and Behavioral Neurobiology (Yehuda, S. & Mostofsky, D. I., eds.), pp. 397-426. Humana Press, Totowa, NJ.
27. Reisbick, S., Neuringer, M., Gohl, E. & Wald, R. (1997) Visual attention in infant monkeys: effects of dietary fats and age. Dev. Psychol. 33: 387-395.
28. Saste, M. D., Carver, J. D., Stockard, J. E., Benford, V. J., Chen, L. T. & Phelps, C. P. (1998) Maternal diet fatty acid composition affects neurodevelopment in rat pups. J. Nutr. 128: 740-743.
29. Sastry, P. S. (1985) Lipids of nervous tissue: composition and metabolism. Prog. Lipid Res. 24: 69-176.
30. Stewart, C. A. & Morris, R. G. (1993) The water maze. In: Behavioural Neuroscience: A Practical Approach. Vol. 1 (Saghal, A., ed.), pp. 107-122. Oxford University Press, New York, NY.
31. Strupp, B. J. & Levitsky, D. A. (1995) Enduring cognitive effects of early malnutrition: a theoretical appraisal. J. Nutr. 125: 2221S-2232S.
32. Tinoco, J., Babcock, R., Hincenbergs, I., Medwadowski, B. & Miljanich, P. (1978) Linolenic acid deficiency: changes in fatty acid patterns in female and male rats raised on a linolenic acid-deficient diet for two generations. Lipids 13: 6-17.
33. Wainwright, P. E. (1997) Essential fatty acids and behaviour: is there a role for the eicosanoids? In: Handbook of Essential Fatty Acid Biology: Biochemistry, Physiology and Behavioral Neurobiology (Yehuda, S., and Mostofsky, D. I., eds.), pp. 299-341. Humana Press, Totowa, NJ.
34. Wainwright, P. E., Huang, Y. S., Bulman-Fleming, B., Lévesque, S. & McCutcheon, D. (1994a) The effects of dietary fatty acid composition combined with environmental enrichment on brain and behavior in mice. Behav. Brain Res. 60: 125-136.
35. Wainwright, P. E., Huang, Y. S., Coscina, D. V., Lévesque, S. & McCutcheon, D. (1994b) Brain and behavioral effects of dietary n-3 deficiency in mice: a three generation study. Dev. Psychobiol. 27:467-487.
36. Wainwright, P. E., Mutsaers, L. M., Jalali, E. & Bell, R. (1996) A comparison of the effects on behavioral development in mice of a diet with a low (n-3): (n-6) ratio with those of malnutrition. AOCS Conference on PUFA in Infant Nutrition: Consensus and Controversies, Barcelona, Spain, November 1996.
37. Wainwright, P. E. & Ward, G. R. (1997) Early nutrition and behavior: a conceptual framework for critical analysis of research. In: Developing Brain and Behavior: The Role of Lipids in Infant Formula (Dobbing, J., ed.), pp. 387-425. Academic Press, London, England.
38. Wainwright, P. E., Xing, H.-C., Girard, T., Parker, L. & Ward, G. R. (1998) Effects of dietary (n-3) fatty acid deficiency on Morris water-maze performance and amphetamine-induced conditioned place preference in rats. Nutr. Neurosci. 1: 281-293.
39. Wainwright, P. E., Xing, H.-C., Mutsaers, L., McCutcheon, D. & Kyle, D. (1997) Arachidonic acid offsets the effects on mouse brain and behavior of a diet with a low (n-6):(n-3) ratio and very high levels of docosahexaenoic acid. J. Nutr. 127: 184-193.
40. Ward, G. R., Huang, Y.-S., Bobik, E., Xing, H.-C., Mutsaers, L., Auestad, N., Montalto, M. & Wainwright, P. E. (1998) Long-chain polyunsaturated fatty acid levels in formulae influence deposition of docosahexaenoic acid and arachidonic acid in brain and red blood cells of artificially reared neonatal rat pups. J. Nutr. 128: 2473-2487.
41. Ward, G. R. & Wainwright, P. E. (1998) The contribution of animal models to understanding the role of fats in infant nutrition. In: Recent Advances in Roles of Lipids in Infant Nutrition (Huang Y.-S. & Sinclair, A. J., eds.), pp. 39-62. AOCS Press, Champaign, IL.
42. Weisinger, H. S., Vingrys, A. J. & Sinclair, A. J. (1996) The effect of docosahexaenoic acid on the electroretinogram of the guinea pig. Lipids 31: 65-70.
43. Werkman, S. H. & Carlson, S. E. (1996) A randomized trial of visual attention of preterm infants fed docosahexaenoic acid until nine months. Lipids 31: 91-97.
44. Whishaw, I. Q. (1995) A comparison of rats and mice in a swimming pool place task and matching to place task: some surprising differences. Physiol. Behav. 58: 687-693.
45. Willats, P., Forsyth, J. S., DiMondugno, M. K., Varma, S. & Colvin, M. (1998) Effect of long-chain polyunsaturated fatty acids in infant formula on problem solving at 10 months of age. Lancet 352: 688-691.