Evolutionary molecular engineering by random elongation mutagenesis

Nature Biotechnology

Volumn 17, Issue 1, 1999, Pages 58-61

  Matsuura, Tomoaki ^a   Miyai, Kouji ^a   Trakulnaleamsai, Savitr ^a   Yomo, Tetsuya ^a,b   Shima, Yasufumi ^a   Miki, Shigeji ^a   Yamamoto, Keizo ^c   Urabe, Itaru ^a  

^a OSAKA UNIVERSITY   (Japan)

^b JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^c NARA MEDICAL UNIVERSITY   (Japan)

Author keywords

Catalase; Directed evolution; Fitness landscape; Random mutagenesis; Sequence space

Indexed keywords

BACTERIAL ENZYME; CATALASE;

ARTICLE; BACTERIUM MUTANT; BIOENGINEERING; ENZYME STABILITY; GEOBACILLUS STEAROTHERMOPHILUS; MOLECULAR EVOLUTION; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL; THERMOSTABILITY;

AMINO ACID SEQUENCE; CATALASE; ENZYME STABILITY; EVOLUTION, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS; MUTATION; PEPTIDES; PROTEIN ENGINEERING;

BACTERIA (MICROORGANISMS); GEOBACILLUS STEAROTHERMOPHILUS;

EID: 0032936541     PISSN: 10870156     EISSN: None     Source Type: Journal    
DOI: 10.1038/5232     Document Type: Article

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