Long-term effect of manidipine on renal function and structure in uninephrectomized spontaneously hypertensive rats

Clinical and Experimental Pharmacology and Physiology

Volumn 24, Issue 7, 1997, Pages 506-512

  Fujimaki, Michitaka ^a   Nagase, Mitsumasa ^a   Uchida, Shunya ^a  

^a TEIKYO UNIVERSITY   (Japan)

Author keywords

Calcium channel blocker; Glomerular hypertension; Spontaneously hypertensive rat; Uninephrectomy

Indexed keywords

CALCIUM CHANNEL BLOCKING AGENT; MANIDIPINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; GLOMERULUS; HYPERTENSION; INULIN CLEARANCE; KIDNEY FUNCTION; KIDNEY HYPERTROPHY; KIDNEY MASS; KIDNEY TUBULE DISORDER; MALE; MORPHOLOGY; NONHUMAN; ORAL DRUG ADMINISTRATION; PROTECTION; PROTEINURIA; RAT; RENOVASCULAR HYPERTENSION; SPONTANEOUSLY HYPERTENSIVE RAT; UNINEPHRECTOMY;

EID: 0030973321     PISSN: 03051870     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1440-1681.1997.tb01236.x     Document Type: Article

References (36)

1. Bauer JH, Reams GR. Renal protection in essential hypertension: How do angiotensin-converting enzyme inhibitors compare with calcium antagonism. J. Am. Soc. Nephrol. 1990; 4 (Suppl. 2): S81-7.
2. Simons JL, Provoost AP, Anderson RS, Rennke HG, Troy JL. Modulation of glomerular hypertension defines susceptibility to progressive glomerular injury. Kidney Int. 1994; 46: 396-404.
3. Komatsu K, Frohlich ED, Ono H, Ono Y, Numabe A, Willis GW. Glomerular dynamics and morphology of aged spontaneously hypertensive rats. Hypertension 1995; 25: 207-13.
4. Dworkin LD, Feiner HD, Parker M, Tolbert E. Effects of nifedipine and enalapril on glomerular structure and function in uninephrectomized SHR. Kidney Int. 1991; 39: 1112-17.
5. Bank N, Alterman L, Aynedjian HS. Selective deep nephron hyperfiltration in uninephrectomized spontaneously hypertensive rats. Kidney Int. 1983; 24: 185-91.
6. Pelayo JC, Harris DCH, Shanley PF, Miller GJ, Schrier RW. Glomerular hemodynamic adaptations in remnant nephrons: Effects of verapamil. Am. J. Physiol. 1988; 254: F425-31.
7. Brunner FP, Thiel G, Hermle M, Bock HA, Mihatsch MJ. Long-term enalapril and verapamil in rats with reduced renal mass. Kidney Int. 1989; 36: 969-77.
8. Tojo A, Kimura K, Matsuoka H, Sugimoto T. Effects of manidipine hydrochloride on the renal microcirculation in spontaneously hypertensive rats. J. Cardiovasc. Pharmacol. 1992; 20: 895-9.
9. Reams GP, Villarreal D, Wu Z, Wang X, Luger AM, Bauer JH. An evaluation of the renal protective effect of manidipine in the uninephrectomized spontaneously hypertensive rat. Am. Heart J. 1993; 125: 620-5.
10. Kimura K, Nanba S, Tojo A, Hirata Y, Matsuoka H, Sugimoto T. Variations in arterioles in spontaneously hypertensive rats. Virchows Arch. A Pathol. Anal. 1989; 415: 565-9.
11. Dworkin LD, Feiner HD. Glomerular injury in uninephrectomized spontaneously hypertensive rats. A consequence of glomerular capillary hypertension. J. Clin. Invest. 1986; 77: 797-809.
12. Weibel ER. Practical methods for biological morphometry in stereological methods. Academic Press, London, 1979.
13. Okuda K, Takahashi S. Measurement of proximal tubular diameter for evaluation of tubular hypertrophy. Nephron 1995; 70: 122.
14. Rise EW. Improved biuret procedure for routine determination of urinary total proteins in clinical proteinuria. Clin. Chem. 1975; 21: 398-401.
15. Judy WV, Watanabe AM, Henry DP, Besch HR Jr, Murphy WR, Hockel GM. Sympathetic nerve activity: Role in regulation of blood pressure in the spontaneously hypertensive rat. Circ. Res. 1976; 38 (Suppl. II): II-21-9.
16. Lundin S, Ricksten SE, Thor n P. Renal sympathetic activity in spontaneously hypertensive rats and normotensive controls, as studied by three different methods. Acta Physiol. Scand. 1984; 120: 265-72.
17. Bidani AK, Schwartz MM, Lewis EJ. Renal autoregulation and vulnerability to hypertensive injury in remnant kidney. Am. J. Physiol. 1987; 252: F1003-10.
18. Takabatake T, Ushiogi Y, Ohta K, Hattori N. Attenuation of enhanced tubuloglomerular feedback activity in SHR by renal denervation. Am. J. Physiol. 1990; 258: F980-5.
19. Morimoto S, Ohyama T, Hisaki K, Matsumura Y. Effects of CV-4093, a new dihydropyridine calcium channel blocker, on renal hemodynamics and function in stroke-prone spontaneously hypertensive rats (SHRSP). Jpn. J. Pharmacol. 1989; 51: 257-65.
20. Shimosawa T, Ando K. Effect of a calcium antagonist on renal hemodynamics in salt-loaded spontaneously hypertensive rats. Jpn. Heart J. 1995; 36: 797-805.
21. Arima S, Ito S, Omata K, Tsunoda K, Yaoita H, Abe K. Diverse effects of calcium antagonists on glomerular hemodynamics. Kidney Int. 1996; 49: S132-4.
22. Anderson S, Rennke HG, Brenner BM. Therapeutic advantage of converting enzyme inhibitors in arresting progressive renal disease associated with systemic hypertension in the rat. J. Clin. Invest. 1986; 77: 1993-2000.
23. Jackson B, Johnston CI. The contribution of systemic hypertension to progression of chronic renal failure in the rat remnant kidney: Effect of treatment with an angiotensin converting enzyme inhibitor or a calcium inhibitor. J. Hypertens. 1988; 6: 495-501.
24. Miller PL, Rennke HG, Meyer TW. Glomerular hypertrophy accelerates hypertensive glomerular injury in rats. Am. J. Physiol. 1991; 261: F459-65.
25. Yoshida Y, Kawamura T, Ikoma M, Fogo A, Ichikawa I. Effects of antihypertensive drugs on glomerular morphology. Kidney Int. 1989; 36: 626-35.
26. Dworkin LG, Benstein JA, Parker M, Tolbert E, Feiner HD. Calcium antagonists and converting enzyme inhibitors reduce renal injury by different mechanisms. Kidney Int. 1993; 43: 808-14.
27. Harris DCH, Hammond WS, Burke TJ, Schrier RW. Verapamil protects against progression of experimental chronic renal failure. Kidney Int. 1987; 31: 41-6.
28. Fine L. The biology of renal hypertrophy. Kidney Int. 1986; 29: 619-34.
29. Hammerman MR, O'Shea M, Miller SB. Role of growth factors in regulation of renal growth. Annu. Rev. Physiol. 1993; 55: 305-21.
30. Wolf G, Mueller E, Stahl RAK, Ziyadeh FN. Angiotensin II-induced hypertrophy of cultured murine proximal tubular cells is mediated by endogenous transforming growth factor-β. J. Clin. Invest. 1993; 92: 1366-72.
31. Katsumata H, Suzuki H, Ohishi A, Nakamoto H, Saruta T, Sakaguchi H. Effects of antihypertensive agents on blood pressure and the progress of renal failure in partially nephrectomized spontaneously hypertensive rats. Lab. Invest. 1990; 62: 474-80.
32. Wolf G, Neilson EG. Angiotensin II as a hypertrophogenic cytokine for proximal tubular cells. Kidney Int. 1993; 43: S100-7.
33. Ling H, Vamvakas S, Schaefer L, Schnittler HJ, Schaefer RM, Heidland A. Angiotensin-II-induced cell hypertrophy: Potential role of impaired proteolytic activity in cultured LLC-PK1 cells. Nephrol. Dial. Transplant. 1993; 10: 1305-12.
34. Huelsemann JL, Sterzel RB, McKenzie DE, Wilcox CS. Effects of a calcium entry blocker on blood pressure and renal function during angiotensin-induced hypertension. Hypertension 1985; 7: 374-9.
35. ter Wee PM, De Micheli AG, Epstein M. Effects of calcium antagonists on renal hemodynamics and progression of nondiabetic chronic renal disease. Arch. Intern. Med. 1994; 154: 1185-202.
36. Kobayashi S, Hishida A. Effects of a calcium antagonist, manidipine, on progressive renal injury associated with mild hypertension in remnant kidneys. J. Lab. Clin. Med. 1995; 125: 572-80.