메뉴 건너뛰기




Volumn 44, Issue 9, 1996, Pages 540-548

Leptin, its receptor and obesity

Author keywords

[No Author keywords available]

Indexed keywords

CARRIER PROTEIN; CELL SURFACE RECEPTOR; LEPTIN; LEPTIN RECEPTOR; PROTEIN;

EID: 0030331944     PISSN: 17088267     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (55)

References (83)
  • 1
    • 0028322089 scopus 로고
    • Increasing prevalence of overweight among US adults. the national health and nutrition examination surveys, 1960 to 1991
    • Kuczmarski RJ, Flegal KM, Campbell SM, Johnson CL. Increasing prevalence of overweight among US adults. The national health and nutrition examination surveys, 1960 to 1991. JAMA 1994;273(3):205-11.
    • (1994) JAMA , vol.273 , Issue.3 , pp. 205-211
    • Kuczmarski, R.J.1    Flegal, K.M.2    Campbell, S.M.3    Johnson, C.L.4
  • 5
    • 0015874760 scopus 로고
    • Central mechanism of feeding
    • Katoni M, ed. Tokyo: Tokyo University Press
    • Oomura Y. Central mechanism of feeding. In: Katoni M, ed. Advances in biophysics. Tokyo: Tokyo University Press, 1973:65-142.
    • (1973) Advances in Biophysics , pp. 65-142
    • Oomura, Y.1
  • 6
    • 0016435353 scopus 로고
    • Metabolic factors in the control of energy stores
    • Bray GA, Campfield LA. Metabolic factors in the control of energy stores. Metabolism 1975;24:99-117.
    • (1975) Metabolism , vol.24 , pp. 99-117
    • Bray, G.A.1    Campfield, L.A.2
  • 7
    • 0020186971 scopus 로고
    • Obesity-inducing hypothalamic knife cuts: Effects on the lipolysis and blood insulin levels
    • Bray GA, Sclafani A, Novin D. Obesity-inducing hypothalamic knife cuts: effects on the lipolysis and blood insulin levels. Am J Physiol 1982;23:R445-9.
    • (1982) Am J Physiol , vol.23
    • Bray, G.A.1    Sclafani, A.2    Novin, D.3
  • 8
    • 0028121685 scopus 로고
    • The VMH-dietary obese rat: A new model of non-insulin dependent diabetes mellitus
    • Axen KV, Li X, Fung K, Sclafani A. The VMH-dietary obese rat: a new model of non-insulin dependent diabetes mellitus. Am J Physiol 1994;266:R921-8.
    • (1994) Am J Physiol , vol.266
    • Axen, K.V.1    Li, X.2    Fung, K.3    Sclafani, A.4
  • 9
    • 85088668799 scopus 로고
    • Reciprocal innervation of the liver: Its significance in metabolic control
    • Szabo AJ, ed. New York: Academic Press
    • Shimazu T. Reciprocal innervation of the liver: its significance in metabolic control, In: Szabo AJ, ed. Advances in metabolic disorders, CNS regulation of carbohydrate metabolism. New York: Academic Press, 1983;10:55-84.
    • (1983) Advances in Metabolic Disorders, CNS Regulation of Carbohydrate Metabolism , vol.10 , pp. 55-84
    • Shimazu, T.1
  • 10
    • 0022190097 scopus 로고
    • Neuroendocrine disorders seen as triggers of the triad: Obesity-insulin resistance-abnormal glucose tolerance
    • Jeanrenaud B, Halimi S, Van de Werve G. Neuroendocrine disorders seen as triggers of the triad: obesity-insulin resistance-abnormal glucose tolerance. Diabetes Metab Rev 1985;1:261-91.
    • (1985) Diabetes Metab Rev , vol.1 , pp. 261-291
    • Jeanrenaud, B.1    Halimi, S.2    Van De Werve, G.3
  • 11
    • 0025935248 scopus 로고
    • Brain neuropeptide Y: An integrator of endocrine, metabolic, and behavioral processes
    • Leibowitz SF. Brain neuropeptide Y: an integrator of endocrine, metabolic, and behavioral processes. Brain Res Bull 1991;27:333-7.
    • (1991) Brain Res Bull , vol.27 , pp. 333-337
    • Leibowitz, S.F.1
  • 13
    • 0021248888 scopus 로고
    • Neuropeptide Y and human pancreatic polypeptide stimulate feeding behavior in rats
    • Clark JT, Kalra PS, Crowley WR, Kalra SP. Neuropeptide Y and human pancreatic polypeptide stimulate feeding behavior in rats. Endocrinology 1984;115:427-9.
    • (1984) Endocrinology , vol.115 , pp. 427-429
    • Clark, J.T.1    Kalra, P.S.2    Crowley, W.R.3    Kalra, S.P.4
  • 15
    • 0025764241 scopus 로고
    • Insatiable feeding evoked in rats by recurrent perfusion of neuropeptide Y in the hypothalamus
    • Paez X, Myers RD. Insatiable feeding evoked in rats by recurrent perfusion of neuropeptide Y in the hypothalamus. Peptides 1991;12:609-16.
    • (1991) Peptides , vol.12 , pp. 609-616
    • Paez, X.1    Myers, R.D.2
  • 16
    • 0026061245 scopus 로고
    • Neuropeptide Y suppresses sympathetic activity to interscapular brown adipose tissue
    • Egawa M, Yoshimatsu H, Bray GA. Neuropeptide Y suppresses sympathetic activity to interscapular brown adipose tissue. Am J Physiol 1991;260:R328-34.
    • (1991) Am J Physiol , vol.260
    • Egawa, M.1    Yoshimatsu, H.2    Bray, G.A.3
  • 17
    • 85050956429 scopus 로고
    • Induction and reversibility of an obese syndrome by intraventricular neuropeptide Y administration to normal rats
    • Vettor R, Zarjevski N. Cusin I, Rohner-Jeanrenaud F, Jeanrenaud B. Induction and reversibility of an obese syndrome by intraventricular neuropeptide Y administration to normal rats. Diabetologia 1994;37:1202-8.
    • (1994) Diabetologia , vol.37 , pp. 1202-1208
    • Vettor, R.1    Zarjevski, N.2    Cusin, I.3    Rohner-Jeanrenaud, F.4    Jeanrenaud, B.5
  • 18
    • 0028228615 scopus 로고
    • Neuropeptide Y and energy balance: One way ahead for the treatment of obesity
    • Dryden S, Frankish H, Wang Q, Williams G. Neuropeptide Y and energy balance: one way ahead for the treatment of obesity. Eur J Clin Invest 1994;24:293-308.
    • (1994) Eur J Clin Invest , vol.24 , pp. 293-308
    • Dryden, S.1    Frankish, H.2    Wang, Q.3    Williams, G.4
  • 19
    • 0025132297 scopus 로고
    • Molecular cloning of a novel G protein-coupled receptor that may belong to the neuropeptide receptor family
    • Eva C, Kreinanene K, Monyer H, Seeburg P, Sprengel R. Molecular cloning of a novel G protein-coupled receptor that may belong to the neuropeptide receptor family. FEBS Lett 1990;271:80-4.
    • (1990) FEBS Lett , vol.271 , pp. 80-84
    • Eva, C.1    Kreinanene, K.2    Monyer, H.3    Seeburg, P.4    Sprengel, R.5
  • 20
    • 0022475083 scopus 로고
    • Brain monoamines and peptides: Role in the control of eating behavior
    • Leibowitz SF. Brain monoamines and peptides: role in the control of eating behavior. Fed Proc 1986;45:1396-403.
    • (1986) Fed Proc , vol.45 , pp. 1396-1403
    • Leibowitz, S.F.1
  • 21
    • 0024582418 scopus 로고
    • Effects of intraventricular infusion of corticotropin-releasing factor on VMH-lesioned obese rats
    • Arase K, Shargill NS, Bray GA. Effects of intraventricular infusion of corticotropin-releasing factor on VMH-lesioned obese rats. Am J Physiol 1989;256:R751-6.
    • (1989) Am J Physiol , vol.256
    • Arase, K.1    Shargill, N.S.2    Bray, G.A.3
  • 22
    • 0024502612 scopus 로고
    • Central corticotropin-releasing factor administration prevents the excessive body weight gain of genetically obese (fa/fa) rats
    • Rohner-Jeanrenaud F, Walker CD, Greco-Perotto R, Jeanrenaud B. Central corticotropin-releasing factor administration prevents the excessive body weight gain of genetically obese (fa/fa) rats. Endocrinology 1989;124:733-9.
    • (1989) Endocrinology , vol.124 , pp. 733-739
    • Rohner-Jeanrenaud, F.1    Walker, C.D.2    Greco-Perotto, R.3    Jeanrenaud, B.4
  • 23
    • 0026659679 scopus 로고
    • Glucagon-like peptide-1, a new hormone of the entero-insularaxis
    • Orskov C. Glucagon-like peptide-1, a new hormone of the entero-insularaxis. Diabetologia 1992;35:701-11.
    • (1992) Diabetologia , vol.35 , pp. 701-711
    • Orskov, C.1
  • 25
    • 0016737525 scopus 로고
    • New peptide in the vertebrate CNS reacting with antigastrin antibodies
    • Vanderhaeghen JJ, Signeau JC, Gepts W. New peptide in the vertebrate CNS reacting with antigastrin antibodies. Nature 1975;257:604-5.
    • (1975) Nature , vol.257 , pp. 604-605
    • Vanderhaeghen, J.J.1    Signeau, J.C.2    Gepts, W.3
  • 26
    • 0017088941 scopus 로고
    • Immunochemical evidence of cholecystokinin-like peptides in brain
    • Dockray GJ. Immunochemical evidence of cholecystokinin-like peptides in brain. Nature 1976;264:568-70.
    • (1976) Nature , vol.264 , pp. 568-570
    • Dockray, G.J.1
  • 27
    • 0001375240 scopus 로고
    • The development and proof of the CCK hypothesis of satiety
    • Cooper SJ, Iversen SD, Iversen LL, eds. Oxford: Oxford University Press
    • Dourish CT, Smithe GP, Gibbs J. The development and proof of the CCK hypothesis of satiety. In: Cooper SJ, Iversen SD, Iversen LL, eds. Multiple CCK receptors in the CNS. Oxford: Oxford University Press, 1992:166-82.
    • (1992) Multiple CCK Receptors in the CNS , pp. 166-182
    • Dourish, C.T.1    Smithe, G.P.2    Gibbs, J.3
  • 28
    • 0028340876 scopus 로고
    • Satiating effect of cholecystokinin
    • Smith GP, Gibbs J. Satiating effect of cholecystokinin. Ann N Y Acad Sci 1994;713:236-41.
    • (1994) Ann N Y Acad Sci , vol.713 , pp. 236-241
    • Smith, G.P.1    Gibbs, J.2
  • 30
    • 0025260137 scopus 로고
    • Brown adipose tissue thermogenesis: Interdisciplinary studies
    • Himms-Hagen J. Brown adipose tissue thermogenesis: interdisciplinary studies. FASEB J 1990;4:2890-8.
    • (1990) FASEB J , vol.4 , pp. 2890-2898
    • Himms-Hagen, J.1
  • 31
    • 0028281432 scopus 로고
    • Impaired expression and functional activity of the β3-and β1-adrenergic receptors in adipose tissue of congenitally obese (C57BL/6J ob/ob) mice
    • Collins S, Daniel KW, Rohlfs EM, Ramkumar V, Taylor IL, Gettys TW. Impaired expression and functional activity of the β3-and β1-adrenergic receptors in adipose tissue of congenitally obese (C57BL/6J ob/ob) mice. Mol Endocrinol 1994;8:518-27.
    • (1994) Mol Endocrinol , vol.8 , pp. 518-527
    • Collins, S.1    Daniel, K.W.2    Rohlfs, E.M.3    Ramkumar, V.4    Taylor, I.L.5    Gettys, T.W.6
  • 33
    • 0028978913 scopus 로고
    • Association of a polymorphism in the β3-adrenergic-receptor gene with features of the insulin resistance syndrome in Finns
    • Widen E, Lehto M, Kanninen T, Walston J, Shuldiner AR, Groop LC. Association of a polymorphism in the β3-adrenergic-receptor gene with features of the insulin resistance syndrome in Finns. N Engl J Med 1995;333:348-51.
    • (1995) N Engl J Med , vol.333 , pp. 348-351
    • Widen, E.1    Lehto, M.2    Kanninen, T.3    Walston, J.4    Shuldiner, A.R.5    Groop, L.C.6
  • 35
    • 0029084089 scopus 로고
    • The β3-adrenergic receptor - A cause and cure of obesity
    • Arner P. The β3-adrenergic receptor - a cause and cure of obesity. N Engl J Med 1995;333:382-3.
    • (1995) N Engl J Med , vol.333 , pp. 382-383
    • Arner, P.1
  • 36
    • 0025828908 scopus 로고    scopus 로고
    • Molecular studies of the uncoupling protein
    • Ricquier D, Casteill L, Bouillaud F. Molecular studies of the uncoupling protein. FASEB J 1996;5:2237-42.
    • (1996) FASEB J , vol.5 , pp. 2237-2242
    • Ricquier, D.1    Casteill, L.2    Bouillaud, F.3
  • 38
    • 0006445309 scopus 로고
    • Identification of genes underlying polygenic obesity in animal models
    • Bouchard C, ed. Boca Raton: CRC Press
    • Warden CH, Fisler JS. Identification of genes underlying polygenic obesity in animal models. In: Bouchard C, ed. The genetics of obesity. Boca Raton: CRC Press, 1994:181-99.
    • (1994) The Genetics of Obesity , pp. 181-199
    • Warden, Ch.1    Fisler, J.S.2
  • 41
    • 0025627770 scopus 로고
    • Fat (fat) and tubby (tub): Two autosomal recessive mutations causing obesity syndromes in the mouse
    • Coleman DL, Elcher EM. Fat (fat) and tubby (tub): two autosomal recessive mutations causing obesity syndromes in the mouse. J Hered 1990;81:424-7.
    • (1990) J Hered , vol.81 , pp. 424-427
    • Coleman, D.L.1    Elcher, E.M.2
  • 47
    • 0000736325 scopus 로고
    • Obese, a new mutation in the house mouse
    • Ingalls AM, Dickie MM, Snell GD. Obese, a new mutation in the house mouse. J Hered 1950;41:317-8.
    • (1950) J Hered , vol.41 , pp. 317-318
    • Ingalls, A.M.1    Dickie, M.M.2    Snell, G.D.3
  • 48
    • 0020045888 scopus 로고
    • Diabetes-obesity syndromes in mice
    • Coleman DL. Diabetes-obesity syndromes in mice. Diabetes 1982;31(1 Suppl):1-6.
    • (1982) Diabetes , vol.31 , Issue.1 SUPPL. , pp. 1-6
    • Coleman, D.L.1
  • 49
    • 0015792424 scopus 로고
    • Effects of parabiosis of obese with diabetes and normal mice
    • Coleman DL. Effects of parabiosis of obese with diabetes and normal mice. Diabetologia 1973;9:294-8.
    • (1973) Diabetologia , vol.9 , pp. 294-298
    • Coleman, D.L.1
  • 55
    • 0029048408 scopus 로고
    • Recombinant mouse OB protein: Evidence for a peripheral signal linking adiposity and central neural networks
    • Campfield LA, Smith FJ, Guisez Y, Devos R, Burn P. Recombinant mouse OB protein: evidence for a peripheral signal linking adiposity and central neural networks. Science 1995;269:546-9.
    • (1995) Science , vol.269 , pp. 546-549
    • Campfield, L.A.1    Smith, F.J.2    Guisez, Y.3    Devos, R.4    Burn, P.5
  • 58
    • 0028821861 scopus 로고
    • The ob gene and insulin. A relationship leading to clues to the understanding of obesity
    • Cusin I, Sainsbury A, Doyle P, Rohner-Jeanrenaud F, Jeanrenaud B. The ob gene and insulin. A relationship leading to clues to the understanding of obesity. Diabetes 1995;44:1467-70.
    • (1995) Diabetes , vol.44 , pp. 1467-1470
    • Cusin, I.1    Sainsbury, A.2    Doyle, P.3    Rohner-Jeanrenaud, F.4    Jeanrenaud, B.5
  • 59
    • 0029021599 scopus 로고
    • Induction of ob gene expression by corticosteroids is accompanied by body weight loss and reduced food intake
    • De Vos P, Saladin R, Auwerx J, Staels B. Induction of ob gene expression by corticosteroids is accompanied by body weight loss and reduced food intake. J Biol Chem 1995;270:15958-61.
    • (1995) J Biol Chem , vol.270 , pp. 15958-15961
    • De Vos, P.1    Saladin, R.2    Auwerx, J.3    Staels, B.4
  • 60
    • 0028826355 scopus 로고
    • Acute cold-induced suppression of ob (obese) gene expression in white adipose tissue of mice: Mediation by the sympathetic system
    • Trayburn P, Thomas MEA, Duncan JS, Rayner DV. Acute cold-induced suppression of ob (obese) gene expression in white adipose tissue of mice: mediation by the sympathetic system. Biochem J 1995;311:729-31.
    • (1995) Biochem J , vol.311 , pp. 729-731
    • Trayburn, P.1    Thomas, M.E.A.2    Duncan, J.S.3    Rayner, D.V.4
  • 62
    • 0029986894 scopus 로고    scopus 로고
    • Localization of binding sites in the central nervous system for leptin (OB protein) in normal, obese (ob/ob), and diabetic (db/db) C57B1/6J mice
    • Malik KF, Young WS. Localization of binding sites in the central nervous system for leptin (OB protein) in normal, obese (ob/ob), and diabetic (db/db) C57B1/6J mice. Endocrinology 1996;137:1497-500.
    • (1996) Endocrinology , vol.137 , pp. 1497-1500
    • Malik, K.F.1    Young, W.S.2
  • 66
    • 0026094772 scopus 로고
    • Altered neuropeptice Y concentrations in specific hypothalamic regions of obese (fa/fa) Zucker rats. Possible relationship to obesity and neuroendocrine disturbances
    • McKibbin PE, Cotton SJ, McMillan S, Holloway B, Mayers R, McCarthy HD, Williams G. Altered neuropeptice Y concentrations in specific hypothalamic regions of obese (fa/fa) Zucker rats. Possible relationship to obesity and neuroendocrine disturbances. Diabetes 1991;40:1423-9.
    • (1991) Diabetes , vol.40 , pp. 1423-1429
    • McKibbin, P.E.1    Cotton, S.J.2    McMillan, S.3    Holloway, B.4    Mayers, R.5    McCarthy, H.D.6    Williams, G.7
  • 67
    • 25744469559 scopus 로고
    • Increased hypothalamic preproneuropeptide Y mRNA in six- To nine-day-old fatty (fa/fa) fats
    • Chung WK, Truett GE, Smoller JW, Hirsch J, Leibel RL. Increased hypothalamic preproneuropeptide Y mRNA in six- to nine-day-old fatty (fa/fa) fats. FASEB J 1992;6:A1785.
    • (1992) FASEB J , vol.6
    • Chung, W.K.1    Truett, G.E.2    Smoller, J.W.3    Hirsch, J.4    Leibel, R.L.5
  • 70
    • 0029083859 scopus 로고
    • Increased obese mRNA expression in omental fat cells from massively obese humans
    • Hamilton BS, Paglia D, Kwan AYM, Deitel M. Increased obese mRNA expression in omental fat cells from massively obese humans. Nat Med 1995;1(9):953-6.
    • (1995) Nat Med , vol.1 , Issue.9 , pp. 953-956
    • Hamilton, B.S.1    Paglia, D.2    Kwan, A.Y.M.3    Deitel, M.4
  • 74
    • 0024244339 scopus 로고
    • Measurement of plasma glucose, free fatty acids, lactate, and insulin for 24 hours in patients with NIDDM
    • Reaven GM, Hollenbeck C, Jeng CY, Wu MS, Chen YDI. Measurement of plasma glucose, free fatty acids, lactate, and insulin for 24 hours in patients with NIDDM. Diabetes 1988;37:1020-4.
    • (1988) Diabetes , vol.37 , pp. 1020-1024
    • Reaven, G.M.1    Hollenbeck, C.2    Jeng, C.Y.3    Wu, M.S.4    Chen, Y.D.I.5
  • 76
    • 0029938057 scopus 로고    scopus 로고
    • Extreme obesity may be linked to markers flanking the human OB gene
    • Reed DR, Ding Y, Xu W, Cather C, Green ED, Price RA. Extreme obesity may be linked to markers flanking the human OB gene. Diabetes 1996;45:691-4.
    • (1996) Diabetes , vol.45 , pp. 691-694
    • Reed, D.R.1    Ding, Y.2    Xu, W.3    Cather, C.4    Green, E.D.5    Price, R.A.6
  • 77
    • 0029885220 scopus 로고    scopus 로고
    • The hypothalamic leptin receptor in humans: Identification of incidental sequence polymorphisms and absence of the db/db mouse and fa/fa fat mutations
    • Considine RV, Considine EL, Williams CJ, Hyde TM, Caro JF. The hypothalamic leptin receptor in humans: identification of incidental sequence polymorphisms and absence of the db/db mouse and fa/fa fat mutations. Diabetes 1996;19:992-4.
    • (1996) Diabetes , vol.19 , pp. 992-994
    • Considine, R.V.1    Considine, E.L.2    Williams, C.J.3    Hyde, T.M.4    Caro, J.F.5
  • 78
    • 0029864416 scopus 로고    scopus 로고
    • Leptin enters the brain by a saturable system independent of insulin
    • Banks WA, Kastin AJ, Huang W, Jaspan JB, Maness LM. Leptin enters the brain by a saturable system independent of insulin. Peptides 1996;17:305-11.
    • (1996) Peptides , vol.17 , pp. 305-311
    • Banks, W.A.1    Kastin, A.J.2    Huang, W.3    Jaspan, J.B.4    Maness, L.M.5
  • 79
    • 0029881125 scopus 로고    scopus 로고
    • Cerebrospinal fluid leptin levels; relationship to plasma levels and to adiposity in humans
    • Schwartz MW, Peskind E, Raskind M, Boyko EJ, Porte D. Cerebrospinal fluid leptin levels; relationship to plasma levels and to adiposity in humans. Nat Med 1996;2:586-93.
    • (1996) Nat Med , vol.2 , pp. 586-593
    • Schwartz, M.W.1    Peskind, E.2    Raskind, M.3    Boyko, E.J.4    Porte, D.5
  • 83
    • 0030020895 scopus 로고    scopus 로고
    • Genes and obesity
    • Andersson LB. Genes and obesity. Ann Med 1996;28:5-7.
    • (1996) Ann Med , vol.28 , pp. 5-7
    • Andersson, L.B.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.