Paradoxical locomotor behavior of dopamine d1 receptor transgenic mice

Experimental Neurology

Volumn 157, Issue 1, 1999, Pages 169-179

  Dracheva, Stella ^a   Xu, Ming ^a   Kelley, Kevin A ^a   Haroutunian, Vahram ^b   Holstein, Gay R ^a   Haun, Shannan ^a   Silverstein, Jeffrey H ^a   Sealfon, Stuart C ^a  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF CINCINNATI MEDICAL CENTER   (United States)

Author keywords

D1 receptor; Dopamine; Locomotion; Parkinson's disease; SKF 81297; Transgenic mice

Indexed keywords

DOPAMINE 1 RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BEHAVIOR; BODY MOVEMENT; BRADYKINESIA; CONTROLLED STUDY; DOPAMINE METABOLISM; DOPAMINERGIC NERVE CELL; LEARNING; LIGAND BINDING; LOCOMOTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECEPTOR BINDING; RECEPTOR GENE; SENSORIMOTOR FUNCTION;

EID: 0032933058     PISSN: 00144886     EISSN: None     Source Type: Journal    
DOI: 10.1006/exnr.1999.7037     Document Type: Article

References (48)

1. Accili D., Fishburn C. S., Drago J., Steiner H., Lachowicz J. E., Park B. H., Gauda E. B., Lee E. J., Cool M. H., Sibley D. R., Gerfen C. R., Westphal H., Fuchs S. A targeted mutation of the D3 dopamine receptor gene is associated with hyperactivity in mice. Proc. Natl. Acad. Sci. USA. 93:1996;1945-1949.
2. Baik J. H., Picetti R., Saiardi A., Thiriet G., Dierich A., Depaulis A., Le Meur M., Borelli E. Parkinsonian-like locomotor impairment in mice lacking dopamine D2 receptors. Nature. 377:1995;424-428.
3. Cabib S., Puglisi-Allegra S. Stress, depression and the mesolimbic dopamine system. Psychopharmacology (Berlin). 128:1996;331-342.
4. Carboni E., Tanda G. L., Frau R., Di Chiara G. Blockade of the noradrenaline carrier increases extracellular dopamine concentrations in the prefrontal cortex: Evidence that dopamine is taken upin vivo. J. Neurochem. 55:1990;1067-1070.
5. Crawley J. N., Paylor R. A proposed test battery and constellations of specific behavioral paradigms to investigate the behavioral phenotypes of transgenic and knockout mice. Horm. Behav. 31:1997;197-211.
6. de Sousa Moreira L. F., Pinheiro M. C., Masur J. Catatonic behavior induced by haloperidol, increased by retesting and elicited without drug in rats. Pharmacology. 25:1982;1-5.
7. Deutch A. Y. Prefrontal cortical dopamine systems and the elaboration of functional corticostriatal circuits: Implications for schizophrenia and Parkinson's disease. J. Neural Transm. Gen. Sect. 91:1993;197-221.
8. Drago J., Gerfen C. R., Lachowicz J. E., Steiner H., Hollon T. R., Love P. E., Ooi G. T., Grinberg A., Lee E. J., Huang S. P. Altered striatal function in a mutant mouse lacking D1A dopamine receptors. Proc. Natl. Acad. Sci. USA. 91:1994;12564-12568.
9. Elsworth J. D., Taylor J. R., Berger P., Roth R. H. Cocaine-sensitive and -insensitive dopamine uptake in prefrontal cortex, nucleus accumbens and striatum. Neurochem. Int. 23:1993;61-69.
10. Ferre S., Gimenez-Llort L., Artigas F., Martinez E. Motor activation in short- and long-term reserpinized mice: Role ofNd. Eur. J. Pharmacol. 255:1994;203-213.
11. Franklin K. B. J., Paxinos G. The Mouse Brain in Stereotaxic Coordinates. 1997;Academic Press, San Diego/London.
12. Fujiwara H. Comparative studies of sulpiride and classical neuroleptics on induction of catalepsy, locomotor activity, and brain dopamine metabolism in mice. Pharmacol. Biochem. Behav. 41:1992;301-308.
13. Giros B., Jaber M., Jones S. R., Wightman R. M., Caron M. G. Hyperlocomotion and indifference to cocaine and amphetamine in mice lacking the dopamine transporter. Nature. 379:1996;606-612.
14. Graybiel A. M. Building action repertoires: Memory and learning functions of the basal ganglia. Curr. Opin. Neurobiol. 5:1995;733-741.
15. Graybiel A. M., Ragsdale C. W. Biochemical anatomy of the striatum. Chemical Neuroanatomy. 1983;Raven Press, New York. p. 427-504.
16. Hogan B., Beddington R., Constantini F., Lacy E. Manipulating the Mouse Embryo. 1994;Cold Spring Harbor Laboratory Press, Cold Spring Harbor. p. 219-250.
17. Hornykiewicz O. Dopamine (3-hydroxytyramine) and brain function. Pharmacol. Rev. 18:1966;925-964.
18. Hu X. T., White F. J. Loss of D1/D2 dopamine receptor synergisms following repeated administration of D1 or D2 receptor selective antagonists: Electrophysiological and behavioral studies. Synapse. 17:1994;43-61.
19. Iversen S. D. The effect of surgical lesions to frontal cortex and substantia nigra on amphetamine responses in rats. Brain Res. 31:1971;295-311.
20. Izenwasser S., Werling L. L., Cox B. M. Comparison of the effects of cocaine and other inhibitors of dopamine uptake in rat striatum, nucleus accumbens, olfactory tubercle, and medial prefrontal cortex. Brain Res. 520:1990;303-309.
21. Jaber M., Robinson S. W., Missale C., Caron M. G. Dopamine receptors and brain function. Neuropharmacology. 35:1996;1503-1519.
22. Kelly M. A., Rubinstein M., Phillips T. J., Lessov C. N., Burkhart-Kasch S., Zhang G., Bunzow J. R., Fang Y., Gerhardt G. A., Grandy D. K., Low M. J. Locomotor activity in D2 dopamine receptor-deficient mice is determined by gene dosage, genetic background, and developmental adaptations. J. Neurosci. 18:1998;3470-3479.
23. Kleven M. S., Perry B. D., Woolverton W. L., Seiden L. S. Effects of repeated injections of cocaine on D1 and D2 dopamine receptors in rat brain. Brain Res. 532:1990;265-270.
24. Koob G. F., Weiss F. Neuropharmacology of cocaine and ethanol dependence. Recent Dev. Alcohol. 10:1992;201-233.
25. Lee S. H., Minowa M. T., Mouradian M. M. Two distinct promoters drive transcription of the human D1A dopamine receptor gene. J. Biol. Chem. 271:1996;25292-25299.
26. Lindvall O., Bjorklund A. General organization of cortical monoamine systems. Descarries L., Reader T. R., Jasper H. H. Monoamine Innervation of Cerebral Cortex. 1984;9-40 Liss, New York.
27. Lowry O. H., Rosebrough N. J., Farr A. L., Randall R. J. Protein measurement with the Folin phenol reagent. J. Biol. Chem. 193:1951;265-275.
28. Mansour A., Meador-Woodruff J. H., Zhou Q. Y., Civelli O., Akil H., Watson S. J. A comparison of D1 receptor binding and mRNA in rat brain using receptor autoradiographic and in situ hybridization techniques. Neuroscience. 45:1991;359-371.
29. Meyer M. E., Cottrell G. A., Van Hartesveldt C. Dopamine D1 antagonists potentiate the durations of bar and cling catalepsy and the dorsal immobility response in rats. Pharmacol. Biochem. Behav. 41:1992;507-510.
30. Meyer M. E., Cottrell G. A., Van Hartesveldt C., Potter T. J. Effects of dopamine D1 antagonists SCH23390 and SKF83566 on locomotor activities in rats. Pharmacol. Biochem. Behav. 44:1993;429-432.
31. Missale C., Nash S. R., Robinson S. W., Jaber M., Caron M. G. Dopamine receptors: From structure to function. Physiol. Rev. 78:1998;189-225.
32. Moratalla R., Xu M., Tonegawa S., Graybiel A. M. Cellular responses to psychomotor stimulant and neuroleptic drugs are abnormal in mice lacking the D1 dopamine receptor. Proc. Natl. Acad. Sci. USA. 93:1996;14928-14933.
33. Nestler E. J. Schizophrenia. An emerging pathophysiology. Nature. 385:1997;578-579.
34. Okubo Y., Suhara T., Suzuki K., Kobayashi K., Inoue O., Terasaki O., Someya Y., Sassa T., Sudo Y., Matsushima E., Iyo M., Tateno Y., Toru M. Decreased prefrontal dopamine D1 receptors in schizophrenia revealed by PET. Nature. 385:1997;634-636.
35. Robbins T. W. Functions of dopamine in the dorsal and ventral striatum. Semin. Neurosci. 4:1992;119-127.
36. Rubinstein M., Phillips T. J., Bunzow J. R., Falzone T. L., Dziewczapolski G., Zhang G., Fang Y., Larson J. L., McDougall J. A., Chester J. A., Saez C., Pugsley T. A., Gershanik O., Low M. J., Grandy D. K. Mice lacking dopamine D4 receptors are supersensitive to ethanol, cocaine, and methamphetamine. Cell. 90:1997;991-1001.
37. Sesack S. R., Hawrylak V. A., Matus C., Guido M. A., Levey A. I. Dopamine axon varicosities in the prelimbic division of the rat prefrontal cortex exhibit sparse immunoreactivity for the dopamine transporter. J. Neurosci. 18:1998;2697-2708.
38. Starr B. S., Starr M. S., Kilpatrick I. C. Behavioural role of dopamine D1 receptors in the reserpine-treated mouse. Neuroscience. 22:1987;179-188.
39. Stoof J. C., Kebabian J. W. Two dopamine receptors: biochemistry, physiology and pharmacology. Life Sci. 35:1984;2281-2296.
40. Surmeier D. J., Song W. J., Yan Z. Coordinated expression of dopamine receptors in neostriatal medium spiny neurons. J. Neurosci. 16:1996;6579-6591.
41. Tanda G., Pontieri F. E., Frau R., Di Chiara G. Contribution of blockade of the noradrenaline carrier to the increase of extracellular dopamine in the rat prefrontal cortex by amphetamine and cocaine. Eur. J. Neurosci. 9:1997;2077-2085.
42. Thierry A. M., Pirot S., Gioanni Y., Glowinski J. Dopamine function in the prefrontal cortex. Adv. Pharmacol. 42:1998;717-720.
43. Vezina P., Blanc G., Glowinski J., Tassin J. P. Opposed behavioural outputs of increased dopamine transmission in prefrontocortical and subcortical areas: A role of cortical D1 dopamine receptor. Eur. J. Neurosci. 3:1991;1001-1007.
44. Williams M., Wright S., Lloyd G. K. Improved therapies for Parkinson's disease: Life beyond dopamine D2/D3 receptor agonists. Trends Pharmacol. Sci. 18:1997;307-310.
45. Xu M., Hu X. T., Cooper D. C., Moratalla R., Graybiel A. M., White F. J, Tonegawa S. Elimination of cocaine-induced hyperactivity and dopamine-mediated neurophysiological effects in dopamine D1 receptor mutant mice. Cell. 79:1994;945-955.
46. Xu M., Koeltzow T. E., Santiago G. T., Moratalla R., Cooper D. C., Hu X. T., White N. M., Graybiel A. M., White F. J., Tonegawa S. Dopamine D3 receptor mutant mice exhibit increased behavioral sensitivity to concurrent stimulation of D1 and D2 receptors. Neuron. 19:1997;837-848.
47. Xu M., Moratalla R., Gold L. H., Hiroi N., Koob G. F., Graybiel A. M., Tonegawa S. Dopamine D1 receptor mutant mice are deficient in striatal expression of dynorphin and in dopamine-mediated behavioral responses. Cell. 79:1994;729-742.
48. Zhou Q. Y., Li C., Civelli O. Characterization of gene organization and promoter region of the rat dopamine D1 receptor gene. J. Neurochem. 59:1992;1875-1883.