-
2
-
-
0029040199
-
Protein tyrosine kinase in the initiation of antigen receptor signaling
-
Bolen, J. B. 1995. Protein tyrosine kinase in the initiation of antigen receptor signaling. Curr. Opin. Immunol. 7:306-331.
-
(1995)
Curr. Opin. Immunol.
, vol.7
, pp. 306-331
-
-
Bolen, J.B.1
-
3
-
-
0028346563
-
Signal transduction by the B cell antigen receptor and its coreceptors
-
Cambier, J. C., C. M. Pleiman, and M. R. Clark. 1994. Signal transduction by the B cell antigen receptor and its coreceptors. Annu. Rev. Immunol. 12:457-486.
-
(1994)
Annu. Rev. Immunol.
, vol.12
, pp. 457-486
-
-
Cambier, J.C.1
Pleiman, C.M.2
Clark, M.R.3
-
4
-
-
0030175744
-
Regulation of antigen receptor signal transduction by protein tyrosine kinases
-
Chan, A. C., and A. S. Shaw. 1995. Regulation of antigen receptor signal transduction by protein tyrosine kinases. Curr. Opin. Immunol. 8:394-401.
-
(1995)
Curr. Opin. Immunol.
, vol.8
, pp. 394-401
-
-
Chan, A.C.1
Shaw, A.S.2
-
5
-
-
0029071585
-
Activation of ZAP-70 kinase activity hy phosphorylation of tyrosine 493 is required for lymphocyte antigen receptor function
-
Chan, A. C., M. Dalton, R. Johnson, G.-H. Kong, T. Wang, R. Thoma, and T. Kurosaki. 1995. Activation of ZAP-70 kinase activity hy phosphorylation of tyrosine 493 is required for lymphocyte antigen receptor function. EMBO J. 14:2499-2508.
-
(1995)
EMBO J.
, vol.14
, pp. 2499-2508
-
-
Chan, A.C.1
Dalton, M.2
Johnson, R.3
Kong, G.-H.4
Wang, T.5
Thoma, R.6
Kurosaki, T.7
-
6
-
-
0025942245
-
The ζ-chain is associated with a tyrosine kinase and upon T cell antigen receptor stimulation associates with ZAP-70, a 70 kilodalton tyrosine phosphoprotein
-
Chan, A. C., B. A. Irving, J. D. Fraser, and A. Weiss. 1991. The ζ-chain is associated with a tyrosine kinase and upon T cell antigen receptor stimulation associates with ZAP-70, a 70 kilodalton tyrosine phosphoprotein. Proc. Natl. Acad. Sci. USA 88:9166-9170.
-
(1991)
Proc. Natl. Acad. Sci. USA
, vol.88
, pp. 9166-9170
-
-
Chan, A.C.1
Irving, B.A.2
Fraser, J.D.3
Weiss, A.4
-
7
-
-
0026483786
-
ZAP-70: A 70kD protein tyrosine kinase that associates with the TCR ζ chain
-
Chan, A. C., M. Iwashima, C. W. Turck, and A. Weiss. 1992. ZAP-70: a 70kD protein tyrosine kinase that associates with the TCR ζ chain. Cell 71:649-662.
-
(1992)
Cell
, vol.71
, pp. 649-662
-
-
Chan, A.C.1
Iwashima, M.2
Turck, C.W.3
Weiss, A.4
-
8
-
-
0028340167
-
ZAP-70 deficiency in an autosomal recessive form of severe combined immunodeficiency
-
Chan, A. C., T. A. Kadlecek, M. E. Elder, A. H. Filipovich, W.-L. Kuo, M. Iwashima, T. G. Parslow, and A. Weiss. 1994. ZAP-70 deficiency in an autosomal recessive form of severe combined immunodeficiency. Science 264:1599-1601.
-
(1994)
Science
, vol.264
, pp. 1599-1601
-
-
Chan, A.C.1
Kadlecek, T.A.2
Elder, M.E.3
Filipovich, A.H.4
Kuo, W.-L.5
Iwashima, M.6
Parslow, T.G.7
Weiss, A.8
-
9
-
-
0028783322
-
Syk tyrosine kinase required for mouse viability and B cell development
-
Cheng, A. M., B. Rowley, W. Pao, A. Hayday, J. B. Bolen, and T. Pawson. 1995. Syk tyrosine kinase required for mouse viability and B cell development. Nature 378:303-306.
-
(1995)
Nature
, vol.378
, pp. 303-306
-
-
Cheng, A.M.1
Rowley, B.2
Pao, W.3
Hayday, A.4
Bolen, J.B.5
Pawson, T.6
-
10
-
-
85038204721
-
-
Submitted for publication
-
Di Bartolo, V., D. Mege, V. Germain, M. Pelosi, E. Dufour, J.-M. Pascussi, F. Michael, G. Magistrelli, A. Isacchi, and O. Acuto. T cell antigen receptor signaling depends on the SH2-mediated association of lck to ZAP-70. Submitted for publication.
-
T Cell Antigen Receptor Signaling Depends on the SH2-mediated Association of lck to ZAP-70
-
-
Di Bartolo, V.1
Mege, D.2
Germain, V.3
Pelosi, M.4
Dufour, E.5
Pascussi, J.-M.6
Michael, F.7
Magistrelli, G.8
Isacchi, A.9
Acuto, O.10
-
11
-
-
0028292001
-
Human severe combined immunodeficiency due to a defect in ZAP-70, a T cell tyrosine kinase
-
Elder, M. E., D. Lin, J. Clever, A. C. Chan, T. J. Hope, A. Weiss, and T. Parslow. 1994. Human severe combined immunodeficiency due to a defect in ZAP-70, a T cell tyrosine kinase. Science 264:1595-1599.
-
(1994)
Science
, vol.264
, pp. 1595-1599
-
-
Elder, M.E.1
Lin, D.2
Clever, J.3
Chan, A.C.4
Hope, T.J.5
Weiss, A.6
Parslow, T.7
-
12
-
-
84988043558
-
Molecular basis for the interactions of the protein tyrosine kinase ZAP-70 with the T cell receptor
-
Hatada, M. H., X. Lu, E. R. Laird, J. Green, J. P. Morgenstern, M. Lou, C. S. Marr, T. B. Phillips, M. K. Ram, K. Theriault, M. J. Zoller, and J. L. Karas. 1995. Molecular basis for the interactions of the protein tyrosine kinase ZAP-70 with the T cell receptor. Nature 377:32-38.
-
(1995)
Nature
, vol.377
, pp. 32-38
-
-
Hatada, M.H.1
Lu, X.2
Laird, E.R.3
Green, J.4
Morgenstern, J.P.5
Lou, M.6
Marr, C.S.7
Phillips, T.B.8
Ram, M.K.9
Theriault, K.10
Zoller, M.J.11
Karas, J.L.12
-
13
-
-
0028209548
-
Sequential interactions of the TCR with two distinct cytoplasmic tyrosine kinases
-
Iwashima, M., B. A. Irving, N. S. C. van Oers, A. C. Chan, and A. Weiss. 1994. Sequential interactions of the TCR with two distinct cytoplasmic tyrosine kinases. Science 263:1136-1139.
-
(1994)
Science
, vol.263
, pp. 1136-1139
-
-
Iwashima, M.1
Irving, B.A.2
Van Oers, N.S.C.3
Chan, A.C.4
Weiss, A.5
-
14
-
-
0029783430
-
Distinct tyrosine phosphorylation sites in ZAP-70 mediate activation and negative regulation of antigen receptor function
-
Kong, G., M. Dalton, J. B. Wardenberg, D. Straus, T. Kurosaki, and A. C. Chan. 1996. Distinct tyrosine phosphorylation sites in ZAP-70 mediate activation and negative regulation of antigen receptor function. Mol. Cell. Biol. 16:5026-5035.
-
(1996)
Mol. Cell. Biol.
, vol.16
, pp. 5026-5035
-
-
Kong, G.1
Dalton, M.2
Wardenberg, J.B.3
Straus, D.4
Kurosaki, T.5
Chan, A.C.6
-
15
-
-
0029076731
-
Reconstitution of Syk function by the ZAP-70 protein tyrosine kinase
-
Kong, G.-H., J.-Y. Bu, T. Kurosaki, A. S. Shaw, and A. C. Chan. 1995. Reconstitution of Syk function by the ZAP-70 protein tyrosine kinase. Immunity 2:485-492.
-
(1995)
Immunity
, vol.2
, pp. 485-492
-
-
Kong, G.-H.1
Bu, J.-Y.2
Kurosaki, T.3
Shaw, A.S.4
Chan, A.C.5
-
16
-
-
14444276991
-
The Cbl phosphotyrosine-binding domain selects a D(N/D)XpY motif and binds to the Tyr292 negative regulatory phosphorylation site of ZAP-70
-
Lupher, M. L., Jr., S. Zhou, S. E. Shoelson, L. C. Cantley, and H. Band. 1997. The Cbl phosphotyrosine-binding domain selects a D(N/D)XpY motif and binds to the Tyr292 negative regulatory phosphorylation site of ZAP-70. J. Biol. Chem. 272:33140-33144.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 33140-33144
-
-
Lupher M.L., Jr.1
Zhou, S.2
Shoelson, S.E.3
Cantley, L.C.4
Band, H.5
-
17
-
-
0029133646
-
Essential role for ZAP-70 in both positive and negative selection of thymocytes
-
Negishi, I., N. Motoyama, K.-I. Nakayama, K. Nakayama, S. Senju, S. Hatakeyama, Q. Zhang, A. C. Chan, and D. Y. Loh. 1995. Essential role for ZAP-70 in both positive and negative selection of thymocytes. Nature 376: 435-438.
-
(1995)
Nature
, vol.376
, pp. 435-438
-
-
Negishi, I.1
Motoyama, N.2
Nakayama, K.-I.3
Nakayama, K.4
Senju, S.5
Hatakeyama, S.6
Zhang, Q.7
Chan, A.C.8
Loh, D.Y.9
-
18
-
-
0029031806
-
Binding of ZAP-70 to phosphorylated T-cell receptor ζ and η enhances its autophosphorylation and generates specific binding sites for SH2 domain-containing proteins
-
Neumeister, E. N., Y. Zhu, S. Richard, C. Terhorst, A. S. Chan, and A. S. Shaw. 1995. Binding of ZAP-70 to phosphorylated T-cell receptor ζ and η enhances its autophosphorylation and generates specific binding sites for SH2 domain-containing proteins. Mol. Cell. Biol. 15:3171-3178.
-
(1995)
Mol. Cell. Biol.
, vol.15
, pp. 3171-3178
-
-
Neumeister, E.N.1
Zhu, Y.2
Richard, S.3
Terhorst, C.4
Chan, A.S.5
Shaw, A.S.6
-
19
-
-
0030046923
-
Dominant-negative ZAP-70 inhibits T cell antigen receptor signaling
-
Qian, D., M. Mollenauer, and A. Weiss. 1998. Dominant-negative ZAP-70 inhibits T cell antigen receptor signaling. J. Exp. Med. 183:611-620.
-
(1998)
J. Exp. Med.
, vol.183
, pp. 611-620
-
-
Qian, D.1
Mollenauer, M.2
Weiss, A.3
-
20
-
-
0030943398
-
T cell antigen receptor signal transduction
-
Qian, D., and A. Weiss. 1997. T cell antigen receptor signal transduction. Curr. Opin. Cell Biol. 9:205-212.
-
(1997)
Curr. Opin. Cell Biol.
, vol.9
, pp. 205-212
-
-
Qian, D.1
Weiss, A.2
-
21
-
-
0029826970
-
c-Rel regulation of IL-2 gene expression may be mediated through activation of AP-1
-
Shapiro, V. S., M. N. Mollenauer, W. C. Greene, and A. Weiss. 1996. c-Rel regulation of IL-2 gene expression may be mediated through activation of AP-1. J. Exp. Med. 184:1663-1670.
-
(1996)
J. Exp. Med.
, vol.184
, pp. 1663-1670
-
-
Shapiro, V.S.1
Mollenauer, M.N.2
Greene, W.C.3
Weiss, A.4
-
22
-
-
0028180858
-
2+ mobilization through distinct pathways
-
2+ mobilization through distinct pathways. EMBO J. 13:1341-1349.
-
(1994)
EMBO J.
, vol.13
, pp. 1341-1349
-
-
Takata, M.1
Sabe, H.2
Hata, A.3
Inazu, T.4
Homma, Y.5
Nukada, T.6
Yamamura, H.7
Kurosaki, T.8
-
23
-
-
0030018304
-
A role for Bruton's tyrosine kinase in B cell antigen receptor-mediated activation of phospholipase C-g2
-
Takata, M., and T. Kurosaki. 1996. A role for Bruton's tyrosine kinase in B cell antigen receptor-mediated activation of phospholipase C-g2. J. Exp. Med. 184:31-40.
-
(1996)
J. Exp. Med.
, vol.184
, pp. 31-40
-
-
Takata, M.1
Kurosaki, T.2
-
24
-
-
0028889302
-
Perinatal lethality and blocked B cell development in mice lacking the tyrosine kinase Syk
-
Turner, M., P. J. Mee, P. S. Costello, O. Williams, A. A. Price, L. P. Duddy, M. T. Furlong, R. L. Geahlen, and V. L. J. Tybulewicz. 1995. Perinatal lethality and blocked B cell development in mice lacking the tyrosine kinase Syk. Nature 378:298-302.
-
(1995)
Nature
, vol.378
, pp. 298-302
-
-
Turner, M.1
Mee, P.J.2
Costello, P.S.3
Williams, O.4
Price, A.A.5
Duddy, L.P.6
Furlong, M.T.7
Geahlen, R.L.8
Tybulewicz, V.L.J.9
-
25
-
-
0027228369
-
Constitutive tyrosine phosphorylation of the T-cell receptor (TCR) ζ subunit: Regulation of TCR-associated protein kinase activity by TCR C
-
van Oers, N. S. C., W. Tao, J. D. Watts, P. Johnson, R. Aebersold, and H.-S. Teh. 1993. Constitutive tyrosine phosphorylation of the T-cell receptor (TCR) ζ subunit: regulation of TCR-associated protein kinase activity by TCR C. Mol. Cell. Biol. 13:5771-5780.
-
(1993)
Mol. Cell. Biol.
, vol.13
, pp. 5771-5780
-
-
Van Oers, N.S.C.1
Tao, W.2
Watts, J.D.3
Johnson, P.4
Aebersold, R.5
Teh, H.-S.6
-
26
-
-
0030250114
-
Complex complexes: Signaling at the TCR
-
Wange, R. L., and L. E. Samelson. 1996. Complex complexes: signaling at the TCR. Immunity 5:197-205.
-
(1996)
Immunity
, vol.5
, pp. 197-205
-
-
Wange, R.L.1
Samelson, L.E.2
-
27
-
-
0029151944
-
Activating and inhibitory mutations in adjacent tyrosines in the kinase domain of ZAP-70
-
Wange, R. L., R. Guitian, N. Isakov, J. D. Watts, R. Aebersold, and L. E. Samelson. 1995. Activating and inhibitory mutations in adjacent tyrosines in the kinase domain of ZAP-70. J. Biol. Chem. 270:18730-18733.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 18730-18733
-
-
Wange, R.L.1
Guitian, R.2
Isakov, N.3
Watts, J.D.4
Aebersold, R.5
Samelson, L.E.6
-
28
-
-
0028985602
-
3, a novel competitive inhibitor of the binding of ZAP-7010 the T cell antigen receptor, blocks early T cell signaling
-
3, a novel competitive inhibitor of the binding of ZAP-7010 the T cell antigen receptor, blocks early T cell signaling. J. Biol. Chem. 270:944-948.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 944-948
-
-
Wange, R.L.1
Isakov, N.2
Burke, J.3
R, T.4
Olaka, A.5
Roller, P.P.6
Watts, J.D.7
Aebersold, R.8
Samelson, L.E.9
-
29
-
-
0027328526
-
Tandem SH2 domains of ZAP-70 bind to T cell antigen receptor ζ and CD3ε from activated Jurkat T cells
-
Wange, R. L., S. N. Malek, S. Desiderio, and L. E. Samelson. 1993. Tandem SH2 domains of ZAP-70 bind to T cell antigen receptor ζ and CD3ε from activated Jurkat T cells. J. Biol. Chem. 268:19797-19801.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 19797-19801
-
-
Wange, R.L.1
Malek, S.N.2
Desiderio, S.3
Samelson, L.E.4
-
30
-
-
0028062116
-
Identification by electrospray ionization mass spectrometry of the sites of tyrosine phosphorylation induced in activated Jurkat T cells on the protein tyrosine kinase ZAP-70
-
Watts, J. D., M. Affolter, D. L. Krebs, R. L. Wange, L. E. Samelson, and R. Aebersold. 1994. Identification by electrospray ionization mass spectrometry of the sites of tyrosine phosphorylation induced in activated Jurkat T cells on the protein tyrosine kinase ZAP-70. J. Biol. Chem. 269:29520-29529.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 29520-29529
-
-
Watts, J.D.1
Affolter, M.2
Krebs, D.L.3
Wange, R.L.4
Samelson, L.E.5
Aebersold, R.6
-
31
-
-
0000082758
-
Phosphorylation of SLP-76 by the ZAP-70 protein-tyrosine kinase is required for T cell receptor function
-
Wardenberg, J. B., C. Fu, J. K. Jackman, H. Flotow, S. E. Wilkinson, D. H. Williams, R. Johnson, G. Kong, A. C. Chan, and P. R. Findell. 1996. Phosphorylation of SLP-76 by the ZAP-70 protein-tyrosine kinase is required for T cell receptor function. J. Biol. Chem. 271:19641-19644.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 19641-19644
-
-
Wardenberg, J.B.1
Fu, C.2
Jackman, J.K.3
Flotow, H.4
Wilkinson, S.E.5
Williams, D.H.6
Johnson, R.7
Kong, G.8
Chan, A.C.9
Findell, P.R.10
-
32
-
-
0028014460
-
Signal transduction by lymphocyte antigen receptors
-
Weiss, A., and D. R. Littman. 1994. Signal transduction by lymphocyte antigen receptors. Cell 76:263-274.
-
(1994)
Cell
, vol.76
, pp. 263-274
-
-
Weiss, A.1
Littman, D.R.2
-
34
-
-
0031912097
-
Genetic evidence for differential coupling of Syk family kinases to the T-cell receptor: Reconstitution studies in a ZAP-70-deficicnt Jurkat T-cell line
-
Williams, B. L., K. L. Schreiber, W. Zhang, R. L. Wange, L. E. Samelson, P. J. Leibson, and R. T. Abraham. 1998. Genetic evidence for differential coupling of Syk family kinases to the T-cell receptor: reconstitution studies in a ZAP-70-deficicnt Jurkat T-cell line. Mol. Cell. Biol. 18:1388-1399.
-
(1998)
Mol. Cell. Biol.
, vol.18
, pp. 1388-1399
-
-
Williams, B.L.1
Schreiber, K.L.2
Zhang, W.3
Wange, R.L.4
Samelson, L.E.5
Leibson, P.J.6
Abraham, R.T.7
-
35
-
-
0027331410
-
p21ras and calcineurin synergize to regulate the nuclear factor of activated T cells
-
Woodrow, M., N. A. Clipstone, and D. Cantrell. 1993. p21ras and calcineurin synergize to regulate the nuclear factor of activated T cells. J. Exp. Med. 178:1517-1522.
-
(1993)
J. Exp. Med.
, vol.178
, pp. 1517-1522
-
-
Woodrow, M.1
Clipstone, N.A.2
Cantrell, D.3
-
36
-
-
0001584956
-
Vav and Slp76 interact and functionally cooperate in IL-2 gene activation
-
Wu, J., D. G. Motto, G. A. Koretzky, and A. Weiss. 1996. Vav and Slp76 interact and functionally cooperate in IL-2 gene activation. Immunity 4:593-602.
-
(1996)
Immunity
, vol.4
, pp. 593-602
-
-
Wu, J.1
Motto, D.G.2
Koretzky, G.A.3
Weiss, A.4
-
38
-
-
0030914118
-
The Vav binding site (Y315) in ZAP-70 is critical for antigen receptor-mediated signal transduction
-
Wu, J., Q. Zhao, T. Kurosaki, and A. Weiss. 1997. The Vav binding site (Y315) in ZAP-70 is critical for antigen receptor-mediated signal transduction. J. Exp. Med. 185:1877-1882.
-
(1997)
J. Exp. Med.
, vol.185
, pp. 1877-1882
-
-
Wu, J.1
Zhao, Q.2
Kurosaki, T.3
Weiss, A.4
-
39
-
-
0029968995
-
Enhancement of lymphocyte responsiveness by a gain-of-function mutation of ZAP-70
-
Zhao, Q., and A. Weiss. 1996. Enhancement of lymphocyte responsiveness by a gain-of-function mutation of ZAP-70. Mol. Cell. Biol. 16:6765-6774.
-
(1996)
Mol. Cell. Biol.
, vol.16
, pp. 6765-6774
-
-
Zhao, Q.1
Weiss, A.2
|