Relationship between serum ferritin and risk factors for ischaemic heart disease in 2235 Danes aged 30-60 years

Journal of Internal Medicine

Volumn 245, Issue 5, 1999, Pages 423-433

  Milman, Nils ^a,b   Kirchhoff, M ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b NAESTVED HOSPITAL   (Denmark)

Author keywords

Blood pressure; Epidemiological survey; Ferritin; Iron metabolism; Ischaemic heart disease; Risk factors; Serum lipids

Indexed keywords

ADULT; ALCOHOL CONSUMPTION; ARTICLE; BODY MASS; CARDIOVASCULAR RISK; CHOLESTEROL BLOOD LEVEL; DENMARK; DIASTOLIC BLOOD PRESSURE; FEMALE; FERRITIN BLOOD LEVEL; HUMAN; ISCHEMIC HEART DISEASE; LIPOPROTEIN BLOOD LEVEL; MAJOR CLINICAL STUDY; MALE; PHYSICAL ACTIVITY; PRIORITY JOURNAL; SEX DIFFERENCE; SMOKING; SYSTOLIC BLOOD PRESSURE;

ADULT; AGE DISTRIBUTION; ALCOHOL DRINKING; BLOOD PRESSURE; BODY MASS INDEX; DENMARK; EXERCISE; FEMALE; FERRITINS; HUMANS; LIPIDS; MALE; MIDDLE AGED; MYOCARDIAL ISCHEMIA; RISK FACTORS; SEX DISTRIBUTION; SMOKING;

EID: 0032930387     PISSN: 09546820     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2796.1999.00465.x     Document Type: Article

References (30)

1. Sullivan JL. The iron paradigm of ischemic heart disease. Am J Heart 1989;117: 1177-88.
2. Williams RE, Zweier JL, Flatherhy JT. Treatment with deferoxamine during ischemia improves functional and metabolic recovery and reduces reperfusion-induced oxygen radical generation in rabbit hearts. Circulation 1991; 83: 1006-14.
3. McCord JM. Is iron sufficiency a risk factor in ischemic heart disease? Circulation 1991; 83: 1112-14.
4. Araujo JA, Romano EL, Brito BE et al. Iron overload augments the development of atherosclerotic lesions in rabbits. Arterioscler Thromb Vasc Biol 1995; 15: 1172-80.
5. Weiner MA, Paige SB, Bailey SR. Antioxidant therapy decreases atherosclerotic plaque burden in an iron loaded animal model. Eur Heart J 1994; 15: 425.
6. Sullivan JL. Iron and the sex difference in heart disease risk. Lancet 1981; ii: 1293-94.
7. Salonen JT, Nyyssnen K, Korpela H, Tuomilehto J, Seppnen R, Salonen R. High stored iron levels are associated with excess risk of myocardial infarction in Eastern Finnish men. Circulation 1992; 86: 803-11.
8. Milman N. Serum ferritin in Danes: studies of iron status from infancy to old age, during blood donation and pregnancy. Int J Hematol 1996; 63: 103-35.
9. Milman N, Kirchhoff M. Iron stores in 1433, 30- to 60-year- old Danish males. Evaluation by serum ferritin and haemoglobin. Scand J Clin Lab Invest 1991; 51: 635-41.
10. Milman N, Kirchhoff M. Iron stores in 1359, 30- to 60-year- old Danish women. Evaluation by serum ferritin and hemoglobin. Ann Hematol 1992; 64: 22-27.
11. Lauffer RB. Iron stores and the international variation in mortality from coronary artery disease. Medical Hypotheses 1990; 35: 96-102.
12. Kannel WB, Hjortland MC, McNamara PN, Gordon T. Menopause and risk of cardiovascular disease. The Framingham Study. Ann Intern Med 1976; 85: 447-52.
13. Walters GO, Miller FM, Worwood M. Serum ferritin concentration and iron stores in normal subjects. J Clin Pathol 1973; 26: 770-72.
14. Milman N, Kirchhoff M, Jorgensen T. Iron status markers, serum ferritin and hemoglobin in 1359 Danish women in relation to menstruation, hormonal contraception, parity and postmenopausal hormone treatment. Ann Hematol 1992; 65: 96-102.
15. Schroll M, Hansen B, Hansen U et al. The incidence of myocardial infarction in Denmark. Results from Dan-Monica 1982-84. Ugeskr Laeg 1993; 155: 296-301.
16. Morrison HI, Semenciw RM, Mayo Y, Wigle DT. Serum iron and risk of fatal myocardial infarction. Epidemiology 1994; 5: 243-46.
17. Stampfer MJ, Grodstein F, Rosenberg I, Willett WC, Hennekens C. A prospective study of plasma ferritin and risk of myocardial infarction in US physicians. Circulation 1993; 87: 688.
18. Magnusson MK, Sigfusson N, Sigvaldson H, Johannesson GM, Magnusson S, Thorgeirsson G. Low iron binding capacity as a risk factor for myocardial infarction. Circulation 1994; 89: 102-108.
19. Sempos CT, Looker AC, Gillum RF, Makuc DM. Body iron stores and the risk of coronary heart disease. N Engl J Med 1994; 330: 1119-24.
20. Ascherio A, Willett WC, Rimm EB, Giovannucci EL, Stampfer MJ. Dietary iron intake and risk of coronary disease among men. Circulation 1994; 89: 969-74.
21. Powell LW, Jazwinska E, Halliday W. Primary iron overload. In: Brock JH, Halliday JW, Pippard MJ, Powell LW, eds. Iron Metabolism in Health and Disease. London: W.B. Saunders, 1994; 255-57.
22. Sempos CT, Looker AC, Gillum RF. Iron and heart disease: the epidemiologic data. Nutr Rev 1996; 54: 73-84.
23. Hein HO, Suadicani P, Gyntelberg F. Alcohol consumption, serum low density lipoprotein cholesterol, and risk of ischaemic heart disease: six year follow up in the Copenhagen male study. Br Med J 1996; 312: 736-41.
24. Milman N, Heitmann BL, Lyhne N, Rosdahl N, Jensen KH, Graudal N. Iron status in 1113 Danish men and women aged 35-65 years: relation to dietary and supplemental iron intake. Scand J Nutr 1993; 37: 98-103.
25. Naimark BJ, Ready AE, Sawatsky JA et al. Serum ferritin and heart disease: the effect of moderate exercise on stored iron levels in postmenopausal women. Can J Cardiol 1996; 12: 1253-57.
26. Leggett BA, Brown NN, Bryant SJ, Duplock L, Powell LW, Halliday JW. Factors affecting the concentration of serum ferritin in a healthy Australian population. Clin Chem 1990; 36: 1350-55.
27. Milman N, Kirchhoff M. Relationship between serum ferritin, alcohol intake, and social status in 2235 Danish men and women. Ann Hematol 1996; 72: 145-51.
28. Rimm EB, Giovannuci EL, Wilett WC et al. Prospective study of alcohol consumption and risk of coronary heart disease in men. Lancet 1991; 338: 464-68.
29. Castelli WP, Gordon T, Hjortland H et al. Alcohol and blood lipids: the cooperative lipoprotein phenotyping study. Lancet 1977; ii: 153-55.
30. Kirchhoff M, Torp-Pedersen C, Hougård K et al. Casual blood pressure in a general Danish population. Relation to age, sex, weight, height, diabetes, serum lipids and consumption of coffee, tobacco and alcohol. J Clin Epidemiol 1994; 47: 469-74.