A novel mechanism for cyclic adenosine 3',5'-monophosphate regulation of gene expression by CREB-binding protein

Molecular Endocrinology

Volumn 13, Issue 2, 1999, Pages 268-275

  Zanger, Kerstin ^a   Cohen, Laurie E ^a   Hashimoto, Koshi ^b   Radovick, Sally ^a   Wondisford, Fredric E ^b,c  

^a BOSTON CHILDREN S HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c Research North 330C   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; TRANSCRIPTION FACTOR PIT 1;

ANIMAL CELL; ARTICLE; GENE EXPRESSION REGULATION; GROWTH HORMONE RELEASE; HORMONAL REGULATION; NONHUMAN; PRIORITY JOURNAL; PROLACTIN RELEASE; PROMOTER REGION; THYROTROPIN RELEASE;

ANIMALS; BLOTTING, WESTERN; CELLS, CULTURED; CREB-BINDING PROTEIN; CYCLIC AMP; CYCLIC AMP-DEPENDENT PROTEIN KINASES; DNA-BINDING PROTEINS; GENE EXPRESSION REGULATION; GLUTATHIONE TRANSFERASE; HUMANS; LUCIFERASES; NUCLEAR PROTEINS; PITUITARY GLAND; PRECIPITIN TESTS; PROLACTIN; PROMOTER REGIONS (GENETICS); RECOMBINANT FUSION PROTEINS; THYROTROPIN-RELEASING HORMONE; TRANS-ACTIVATORS; TRANSCRIPTION FACTOR PIT-1; TRANSCRIPTION FACTORS; TRANSFECTION;

ANIMALIA;

EID: 0032927943     PISSN: 08888809     EISSN: None     Source Type: Journal    
DOI: 10.1210/me.13.2.268     Document Type: Article

References (39)

1. 1. Rosenfeld MG 1991 POU-domain transcription factors: pou-er-ful developmental regulators. Genes Dev 5:897-907
2. 2. Bodner M, Castrillo JL, Theill LE, Deerinck T, Ellisman M, Karin M 1988 The pituitary-specific transcription factor GHF-1 is a homeobox-containing protein. Cell 55:505-518
3. 3. Ingraham HA, Chen R, Mangalam HJ, Elsholtz HP, Flynn SE, Lin CR, Simmons DM, Swanson L, Rosenfeld MG 1988 A tissue-specific transcription factor containing a homeodomain specifies a pituitary phenotype. Cell 55:519-529
4. 4. Theill LE, Castrillo J-L, Wu D, Karin M 1989 Dissection of functional domains of the pituitary-specific transcription factor GHF-1. Nature 342:945-948
5. 5. Mangalam HJ, Albert VR, Ingraham HA, Kapiloff M, Wilson L, Nelson C, Elsholtz H, Rosenfeld MG 1989 A pituitary POU domain protein, Pit-1, activates both growth hormone, prolactin promoters transcriptionally. Genes Dev 3:946-958
6. 6. Chen R, Ingraham HA, Treacy MN, Albert VR, Wilson L, Rosenfeld MG 1990 Autoregulation of pit-1 gene expression mediated by two cis-active promoter elements. Nature 346:583-586
7. 7. McCormick A, Brady H, Theill LE, Karin M 1990 Regulation of the pituitary-specific homeobox gene GHF1 by cell-autonomous, environmental cues. Nature 345: 829-832
8. 8. Steinfelder HJ, Hauser P, Nakayama Y, Radovick S, McClaskey JH, Taylor T, Weintraub BD, Wondisford FE 1991 Thyrotropin-releasing hormone regulation of human TSH-β expression: role of a pituitary-specific transcription factor (Pit-1/ GHF-1), potential interaction with a thyroid hormone-inhibitory element. Proc Natl Acad Sci USA 88:3130-3134
9. 9. Supowit SC, Ramsey T, Thompson EB 1992 Extinction of prolactin gene expression in somatic cell hybrids is correlated with the repression of the pituitary-specific transactivator GHF-1/Pit-1. Mol Endocrinol 6:786-792
10. 10. d'Emden MC, Okimura Y, Maurer RA 1992 Analysis of functional cooperativity between individual transcription-stimulating elements in the proximal region of the rat prolactin gene. Mol Endocrinol 6:581-588
11. 11. Keech CA, Jackson SM, Siddiqui SK, Ocran KW, Gutierrez-Hartmann A 1992 Cyclic adenosine 3′,5′-monophosphate activation of the rat prolactin promoter is restricted to the pituitary-specific cell type. Mol Endocrinol 6:2059-2070
12. 12. Steinfelder HJ, Radovick S, Mroczynski MA, Hauser P, McClaskey JH, Weintraub BD, Wondisford FE 1992 Role of a pituitary-specific transcription factor (pit-1/GHF-1) or a closely related protein in c AMP regulation of human thyrotropin-β subunit gene expression. J Clin Invest 89:409-419
13. 13. Fischberg DJ, Chen X, Bancroft CA 1994 pit-1 phosphorylation mutant can mediate both basal, induced prolactin, growth hormone promoter activity. Mol Endocrinol 8:1566-1573
14. 14. Okimura Y, Howard PW, Maurer RA 1994 Pit-1 binding sites mediate transcriptional responses to cyclic adenosine 3′,5′-monophosphate through a mechanism that does not require inducible phosphorylation of pit-1. Mol Endocrinol 8:1559-1565
15. 15. Baringa M, Yamamoto G, Rivier C, Vale W, Evans R, Rosenfeld MG 1983 Transcriptional regulation of growth hormone gene expression by growth hormone-releasing factor. Nature 306:84-85
16. oα-mediated signaling in the Pit-1-dependent inhibition of the prolactin gene promoter. J Biol Chem 269:12007-12013
17. 17. Gershengorn MC 1986 Mechanism of thyrotropin-releasing hormone stimulation of pituitary hormone secretion. Annu Rev Physiol 48:515-526
18. 18. Chrivia JC, Kwok RP, Lamb N, Hadiwara M, Montminy MR, Goodman RH 1993 Phosphorylated CREB binds specifically to the nuclear protein CBP. Nature 365:855-859
19. 19. Arany Z, Sellers WR, Livingston DM, Ecker R 1994 E1A-associated p 300, CREB-associate CBP belong to a conserved family of coactivators. Cell 77:799-800
20. 20. Arias J, Alberts AS, Brindle P, Claret FX, Smeal T, Karin M, Feramisco J, Montminy M 1994 Activation of cAMP, mitogen responsive genes relies on a common nuclear factor. Nature 370:226-228
21. 21. Eckner R, Ewen ME, Newsome D, Gerdes M, DeCaprio JA, Lawrence JE, Livingston DM 1994 Molecular cloning, functional analysis of the adenovirus E1 A-associated 300-kD protein (p300) reveals a protein with properties of a transcriptional adapter. Genes Dev 8:869-884
22. 22. Kwok RP, Lundblad JR, Chrivia JC, Richards JP, Bachinger HP, Brennan RG, Roverts SGE, Green MR, Goodman RH 1994 Nuclear protein CBP is a coactivator for the transcription factor CREB. Nature 370:223-226
23. 23. Lundblad JR, Kwok RP, Laurance ME, Harter ML, Goodman RH 1995 Adenoviral E1 A-associated protein p300 as a functional homologue of the transcriptional co-activator CBP. Nature 374:85-88
24. 24. Ogryzko W, Schilz L, Russanova V, Howard BH, Nakatni Y 1996 The transcriptional coactivators p300, CBP are histone acetyltransferases. Cell 87:953-959
25. 25. Sharp ZD 1995 Rat Pit-1 stimulates transcription in vitro by influencing pre-initiation complex assembly. Biochem Biophys Res Commun 206:40-45
26. 26. Kee BL, Arias J, Montminy MR 1996 Adaptor-mediated recruitment of RNA polymerase II to a signal-dependent activator. J Biol Chem 271:2373-2375
27. 27. Nakajima T, Uchida C, Anderson SF, Lee C-G, Hurwitz J, Parvin JD, Montminy M 1997 RNA helicase A mediates association of CBP with RNA polymerase II Cell 90:1107-1112
28. 28. Chawla S, Hardingham GE, Quinn DR, Bading H 1998 CBP: a signal-regulated transcriptional coactivator controlled by nuclear calcium, CaM kinase IV Nature 281:1505-1509
29. 29. Kamei Y, Xu L, Heinzel T, Torchia J, Kukokawa R, Gloss B, Lin S-C, Heyman RA, Rose DW, Glass CK, Rosenfeld MG 1996 A CBP integrator complex mediates transcriptional activation, AP-1 inhibition by nuclear receptors. Cell 85:403-414
30. 30. Maurer RA 1989 Both isoforms of the cAMP-dependent protein kinase catalytic subunit can activate transcription of the prolactin gene. J Biol Chem 264:6870-6873
31. 31. Straub RE, Frech GC, Joho RH, Gershengorn MC 1990 Expression cloning of a cDNA encoding the mouse pituitary thyrotropin-releasing hormone receptor. Proc Natl Acad Sci USA 87:9514-9518
32. 32. Li S, Crenshaw EB, Rawson EJ, Simmons DM, Swanson LW, Rosenfeld MG 1990 Dwarf locus mutants lacking three pituitary cell types result from mutations in the POU-domain gene pit-1. Nature 347:528-533
33. 33. Konzak KE, Moore DD 1992 Functional isoforms of Pit-1 generated by alternative mRNA splicing. Mol Endocrinol 6:241-247
34. 34. Morris AE, Kloss B, McChesney RE, Bancroft C, Chasin LA 1992 An alternatively spliced Pit-1 isoform altered in its ability to trans-activate. Nucleic Acids Res 20:1355-1361
35. 35. Theill LE, Hattori K, Lazzaro D, Castrillo J-L, Karin M 1992 Differential splicing of the GHF 1 primary transcript gives rise to two functionally distinct homeodomain proteins. EMBO J 11:2261-2269
36. 36. Deutsch PJ, Jameson JL, Habener JF 1987 Cyclic AMP responsiveness of the human gonadotropin-a gene transcription is directed by a repeated 18-base pair enhancer. J Biol Chem 262:12169-12174
37. 37. Gonzalez GA, Montminy MR 1989 Cyclic AMP stimulates somatostatin gene transcription by phosphorylation of CREB at serine 133. Cell 59:675-680
38. 38. Kapiloff MS, Farkash Y, Wegner M, Rosenfeld MG 1991 Variable effects of phosphorylation of Pit-1 dictated by the DNA response elements. Science 253:786-789
39. 39. Xu L, Lavinsky RM, Dasen JS, Flynn SE, McInerney EM, Mullen T-M, Heinzel T, Szeto D, Korzus E, Kurokawal R, Aggarwal AK, Rose DW, Glass CK, Rosenfeld MG 1998 Signal-specific co-activator domain requirements for Pit-1 activation. Nature 395:301-306