Topology of the Shaker potassium channel probed with hydrophilic epitope insertions

Journal of Cell Biology

Volumn 136, Issue 5, 1997, Pages 1037-1045

  Shih, Theodore M ^a   Goldin, Alan L ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; EPITOPE; MONOCLONAL ANTIBODY; POTASSIUM; POTASSIUM CHANNEL;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; ELECTROPHYSIOLOGY; HYDROPHILICITY; IMMUNOFLUORESCENCE TEST; MODEL; NONHUMAN; POTASSIUM CURRENT; PRIORITY JOURNAL; VOLTAGE CLAMP; XENOPUS;

ANIMALS; CELL MEMBRANE; ELECTRIC CONDUCTIVITY; EPITOPES; MUTATION; OOCYTES; PATCH-CLAMP TECHNIQUES; PEPTIDES; POTASSIUM CHANNELS; PROTEIN CONFORMATION; RECOMBINANT FUSION PROTEINS; SHAKER SUPERFAMILY OF POTASSIUM CHANNELS; XENOPUS LAEVIS;

ANIMALIA;

EID: 0030896795     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.136.5.1037     Document Type: Article

References (28)

1. Bezanilla, F., and C.M. Armstrong. 1977. Inuctivalion of the sodium channel-sodium current experiments. J. Gen. Physiol. 70:549-566.
2. Catterall, W.A. 1993. Structure and function of voltage-gated ion channels. Trends Neurosci. 16:500-506.
3. + channel inactivation gating by the cAMP-dependent protein kinase. Neuron. 12:1097-1109.
4. Durell, S.R., and H.R. Guy. 1992. Atomic scale structure and functional models of voltage-gated potassium channels. Biophys. J. 62:238-250.
5. Goldin, A.L. 1991. Expression of ion channels by injection of mRNA into Xennpus oocytes. Methods Cell Biol. 36:487-509.
6. Greenblatt, R.E., Y. Blatt, and M. Montal. 1985. The structure of the voltage-sensitive sodium channel inferences derived from computer-aided analysis of the Electrophorus electricus channel primary structure. FEBS (Fed. Eur. Biochem. Soc.) Lett. 193:125-134.
7. + channels. Science (Wash. DC). 251:942-944.
8. Hoshi, T., W.N. Zagotta, and R.W. Aldrich. 1990. Biophysical and molecular mechanisms of Shaker potassium channel inactivation, Science (Wash. DC). 250:533-538.
9. + channels: effects of alterations in the carboxy-terminal region. Neuron. 7:547-556.
10. + channel. Nature (Lond.). 353:86-90.
11. + channels. Am. J. Physiol. 261:C583-C590.
12. Kosower, E.M. 1985. A structural and dynamic molecular model for the sodium channel of Electrophorus etectricus. FEBS (Fed. Eur. Biochem. Soc.lLett. 182:234-242.
13. Li, M., Y.N. Jan, and L.Y. Jan. 1992. Specification of subunit assembly by the hydrophilic amino-terminal domain of the Shaker potassium channel. Science (Wash. DC). 257:1225-1230.
14. + channel. Nature (Lond.). 353:752-756.
15. + channels. Neurun. 7:327-336.
16. Lopez-Barneo, J., T. Hoshi, S.H. Heinemann, and R.W. Aldrich. 1993. Effects of external cations and mutations in the pore region on C-type inactivation of Shaker potassium channels. Receptors and Channels. 1:61-71.
17. + channels. Science (Wash. DC). 250:276-279.
18. MacKinnon, R., L. Heginbotham, and T. Abramson. 1990. Mapping the receptor situ for a pore-blocking potassium channel inhibitor. Neuron. 5:767-771.
19. Nakai, J., B.A. Adams, K. Imoto, and K.G. Beam. 1994. Critical roles of the S3 segment and S3-S4 linker of repeat I in activation of L-type calcium channels. Proc. Natl. Acad. Sci. USA. 91:1014-1018.
20. Papazian, D.M., L.C. Timpe, Y.N. Jan, and L.Y. Jan. 1991. Alteration of voltage-dependence of Shaker potassium channel by mutations in the S4 sequence. Nature (Lund.). 349:305-310.
21. Papazian, D.M., X.M. Shao, S.-A. Seoh, A.F. Mock, Y. Huang, and D.H. Wainstock. 1995. Electrostatic interactions of S4 voltage sensor in Shaker K' channel Neuron. 14:1293-1301.
22. Patton, D.E., J.W. West, W.A. Catterall, and A.L. Goldin, 1993. A peptide segment critical for sodium channel inactivation functions as an inactivation gate in a potassium channel. Neuron. 11:967-974.
23. Santacruz-Toloza, L., Y. Huang, S.A. John, and D.M. Papazian. 1994. Glycosylation of shaker potassium channel protein in insect cell culture and in Xenopus oocytes. Biochemistry. 33:5607-5613.
24. Sawaryn, A., and H. Drouin. 1991. Reevaluation of hydropathy profiles of voltage-gated ionic channels. Experientia (Basel). 47:962-964.
25. + channel. Neuron. 16:1159-1167.
26. Slesinger, P.A., Y.N. Jan, and L.Y. Jan. 1993. The S4-S5 loop contributes to the ion-selective pore of potassium channels. Neuron. 11:739-749.
27. + channel by mutation of the H5 region. Nature (Land.). 349:700-704.
28. Zagotta, W.N., T. Hoshi, and R.W. Aldrich. 1990. Restoration of inactivation in mutants of Shaker potassium channels by a peptide derived from ShB. Science (Wash. DC). 250:568-571.