Ten pulmonary chondroid hamartomas with chromosome 6p21 breakpoints within the HMG-I(Y) gene for its immediate surroundings

Journal of the National Cancer Institute

Volumn 88, Issue 17, 1996, Pages 1234-1236

  Kazmierczak, Bernd ^a   Wanschura, Sylke ^a   Rommel, Birgit ^a   Bartnitzke, Sabine ^a   Bullerdiek, Jörn ^a  

^a UNIVERSITY OF BREMEN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CHROMOSOME 6P; CHROMOSOME ABERRATION; CLINICAL ARTICLE; CONTROLLED STUDY; GENE AMPLIFICATION; HAMARTOMA; HUMAN; HUMAN TISSUE; LUNG TUMOR;

EID: 0029759372     PISSN: 00278874     EISSN: None     Source Type: Journal    
DOI: 10.1093/jnci/88.17.1234     Document Type: Article

References (10)

1. Johansson M, Dietrich C, Mandahl N, Hambraeus G, Johansson L, Clausen PP, et al. Recombinations of chromosomal bands 6p21 and 14q24 characterise pulmonary hamartomas. Br J Cancer 1993;67:1236-41.
2. Fletcher JA, Longtine J, Wallace K, Mentzer SJ, Sugarbaker DJ. Cytogenetic and histologic findings in 17 pulmonary chondroid hamartomas: evidence for a pathogenetic relationship with lipomas and leiomyomas. Genes Chromosomes Cancer 1995;12:220-3.
3. Sreekantaiah C, Leong SP, Fleming S, Sandberg AA. Translocation (2;6)(q36;p21.3) in a lipoma. Cancer Genet Cytogenet 1990; 45:81-4.
4. Mark J, Havel G, Grepp C, Dahlenfors R, Wedell B. Cytogenetical observations in human benign uterine leiomyomas. Anticancer Res 1988;8:621-6.
5. Schoenmakers EF. Wanschura S, Mols R, Bullerdiek J, van den Berghe H, Van de Ven WJ. Recurrent rearrangements in the high mobility group protein gene HMGI-C, in benign mesenchymal tumours. Nat Genet 1995;10:436-44.
6. Kazmierczak B, Wanschura S, Rosigkeit J, Meyer-Bolte K, Uschinsky K, Haupt R, et al. Molecular characterization of 12q14-l5 rearrangements in three pulmonary chondroid hamartomas. Cancer Res 1995;55:2497-9.
7. Kazmierczak B, Wanschura S, Meyer-Bolte K, Caselitz J, Meister P, Bartnitzke S, et al. Cytogenetic and molecular analysis of an aggressive angiomyxoma. Am J Pathol 1995; 147:580-5.
8. Friedmann M, Holth LT, Zoghbi HY, Reeves R. Organization, inducible-expression and chromosome localization of the human HMG-I(Y) nonhistone protein gene. Nucleic Acids Res 1993;21:4259-67.
9. Du W, Maniatis T. The high mobility group protein HMG I(Y) can stimulate or inhibit DNA binding of distinct transcription factor ATF-2 isoforms. Proc Natl Acad Sci U S A 1994;91:11318-22.
10. Kim J, Reeves R, Rothman P, Boothby M. The non-histone chromosomal protein HMG-I(Y) contributes to repression of the immunoglobulin heavy chain germ-line epsilon RNA promoter. Eur J Immunol 1995;25:798-808.