Transcriptional activation of gonadotropin-releasing hormone (GnRH) receptor gene by GnRH: Involvement of multiple signal transduction pathways

Endocrinology

Volumn 140, Issue 1, 1999, Pages 358-364

  Lin, Xinwei ^a   Conn, P Michael ^a,b  

^a OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^b OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM ION; CYCLIC AMP; FOLLITROPIN; GONADORELIN; GONADORELIN RECEPTOR; LUTEINIZING HORMONE; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN KINASE C;

ANIMAL CELL; ARTICLE; GENE OVEREXPRESSION; GENETIC TRANSCRIPTION; GONADORELIN RELEASE; HORMONE RECEPTOR INTERACTION; HYPOTHALAMUS HYPOPHYSIS SYSTEM; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR GENE; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION;

EID: 0032922608     PISSN: 00137227     EISSN: None     Source Type: Journal    
DOI: 10.1210/endo.140.1.6452     Document Type: Article

References (48)

1. 1. Conn PM 1994 The molecular mechanism of gonadotropin-releasing hormone action in the pituitary. In: Knobil E, Neill JD (eds) The Physiology of Reproduction. Raven Press, New York, pp 1815-1832
2. 2. Sealfon SC, Weinstein H, Millar RP 1997 Molecular mechanisms of ligand interaction with the gonadotropin-relcasing hormone receptor. Endocr Rev 18:180-205
3. 3. Hawes BE, Barnes S, Conn PM 1993 Cholera toxin and pertussis toxin provoke differential effects on luteinizing hormone release, inositol phosphate production, and gonadotropin-releasing hormone (GnRH) receptor binding in the gonadotrope: evidence for multiple guanyl nucleotide binding proteins in GnRH action. Endocrinology 132:2124-2130
4. 11. Mol Endocrinol 6:1673-1681
5. 11α, equally. Mol Pharmacol 46:1-7
6. q/11α by the gonadotropin-releasing hormone receptor. Mol Endocrinol 11:738-746
7. 7. Conn PM, Janovick JA, Stanislaus D, Kuphal D, Jennes L 1995 Molecular and cellular basis of gonadotropin-releasing hormone action in the pituitary and central nervous system. In: Litwack G (ed) Vitamins and Hormones. Academic Press, New York, vol 50:151-214
8. 2+-independent release of LH. Mol Cell Endocrinol 58:155-160
9. 9. Borgeat P, Chavancy G, Dupont A, Labrie F, Arimura A, Schally AV 1972 Stimualtion of adenosine 3′:5′-cyclic monophosphate accumulation in anterior pituitary gland in vitro by synthetic luteinizing hormone-releasing hormone. Proc Natl Acad Sci USA 69:2677-2681
10. 10. Tashjian AH JR, Yasumura Y, Levine L, Sato GH, Parker ML 1968 Establishment of clonal strains of rat pituitary tumor cells that secrete growth hormone. Endocrinology 82:342-352
11. 3 cells stably transfected with gonadotropin-releasing hormone receptor complementary deoxyribonucleic acid. Endocrinology 135:2220-2227
12. 12. Kaiser UB, Conn PM, Chin WW 1997 Studies of gonadotropin-releasing hormone (GnRH) action using GnRH receptor-expressing pituitary cell lines. Endocr Rev 18:46-70
13. 13. Kaiser UB, Sabbagh E, Saunders BD, Chin WW 1998 Identification of cis-acting deoxyribonucleic acid elements that mediate gonadotropin-releasing hormone stimulation of the rat luteinizing hormone β-subunit gene. Endocrinology 139:2443-2451
14. 3 cells stably transfected with rat GnRH receptor complementary deoxyribonucleic acid. Endocrinology 135:2214-2219
15. 3 cells with rat gonadotropin-releasing hormone receptor complementary deoxyribonucleic acid results in expression of a receptor coupled to cyclic adenosine 3′,5′-monophosphate-dependent prolactin release via a G-protein. Endocrinology 135:315-320
16. 16. Lin X, Janovick JA, Brothers S, Blomenröhr M, Bogerd J, Conn PM 1998 Addition of catfish gonadotropin-releasing hormone (GnRH) receptor intracellualr carboxyl-terminal tail to rat GnRH receptor alters receptor expression and regulation. Mol Endocrinol 12:161-171
17. 3 cells: evidence from palmitoylation and overexpression of G-proteins. Biol Reprod 59:579-586
18. 18. Van Biesen T, Luttrell LM, Hawes BE, Lefkowitz RJ 1996 Mitogenic signaling via G protein-coupled receptors. Endocr Rev 17:698-714
19. 19. Gutkind JS 1998 The pathways connecting G protein-coupled receptors to the nucleus through devergent mitogen-activated protein kinase cascades. J Biol Chem 273:1839-1842
20. 20. Campbell JS, Seger R, Graves JD, Graves LM, Jensen AM, Krebs EG 1995 The MAP kinase cascade. Recent Prog Horm Res 50:131-159
21. 21. Ohmichi M, Sawasa T, Kanda Y, Koike K, Hirota K, Miyake A, Saltiel AR 1994 Thyrotropin-releasing hormone stimulates MAP kinase activity in GH3 cells by divergent pathways. J Biol Chem 269:3783-3788
22. 22. Mitchell R, Sim PJ, Leslie T, Johnson MS, Thomson FJ 1994 Activation of MAP kinase associated with the priming effect of LHRH. J Endocrinol 140:R15-R18
23. 23. Sim PJ, Wolbers WB, Mitchell R 1995 Activation of MAP kinase by the LHRH receptor through a dual mechanism involving protein kinase C and a pertussis toxin-sensitive G protein. Mol Cell Endocrinol 112:257-263
24. 2+ and protein kinase C. Endocrinology 138:1673-1682
25. 25. Roberson MS, Misra-Press A, Laurance ME, Stork PJS, Maurer RA 1995 A role for mitogen-activatcd protein kinase in mediating activation of the glycoprotein hormone a-subunit promoter by gonadotropin-releasing hormone. Mol Cell Biol 15:3531-3539
26. 26. Sundaresan S, Colin IM, Pestell RG, Jameson JL 1996 Stimualrion of mitogen-activated protein kinase by gonadotropin-releasing hormone: evidence for the involvement of protein kinase C. Endocrinology 137:304-311
27. 2+ influx and mitogen-activated protein kinase-signaling pathways. Mol Endocrinol 12:451-457
28. 28. Saunders BD, Sabbagh E, Chin WW, Kaiser UB 1998 Differential use of signal transduction pathways in the gonadotropin-releasing hormone-mediated regulation of gonadotropin subunit gene expression. Endocrinology 139:1835-1843
29. 29. Bauer-Dantoin AC, Hollenberg AN, Jameson JL 1993 Dynamic regulation of gonadotropin-releasing hormone receptor mRNA levels in the anterior pituitary gland during the rat estrous cycle. Endocrinology 133:1911-1914
30. 30. Brooks J, Taylor PL, Saunders PTK, Eidne KA, Struthers WJ, McNeilly AS 1993 Cloning and sequencing of the sheep pituitary gonadotropin-releasing hormone receptor and changes in expression of its mRNA during the estrous cycle. Mol Cell Endocrinol 94:R23-R27
31. 1. Lin X, Conn PM 1998 Transcriptional activation of gonadotropin-releasing hormone (GnRH) receptor gene by GnRH and cyclic adenosine monophosphate. Endocrinology 139:3896-3902
32. 32. Albarracin CT, Kaiser, UB, Chin WW 1994 Isolation and characterization of the 5′-flanking region of the mouse gonadotropin-releasing hormone receptor gene. Endocrinology 135:2300-2306
33. q family members couple parathyroid hormone (PTH)/PTH-related peptide and calcitonin receptors to phospholipase C in COS-7 cells. Mol Endocrinol 10:566-574
34. 34. Frost JA, Geppert TD, Cobb MH, Feramisco JR 1994 A requirement for extracellular signal-regulated kinase (ERK) function in the activation of AP-1 by Ha-Ras, phorbol 12-myristate 13-acetate, and serum. Proc Natl Acad Sci USA 91:3844-3848
35. 35. Robbins DJ, Zhen E, Owaki H, Vanderbilt CA, Ebert D, Geppert TD, Cobb MH 1993 Regulation and properties of extracellular signal-regulated protein kinases 1 and 2 in vitro. J Biol Chem 268:5097-5106
36. 36. Beck TW, Huleihel M, Gunnell M, Bonner TI, Kapp UR 1987 The complete coding sequence of the human A-raf-1 oncogene and transforming activity of a human A-raf carrying retrovirus. Nucleic Acids Res 15:595-609
37. 37. McArdle CA, Conn PM 1989 Use of protein kinase C-depleted cells for investigation of the role of protein kinase C in stimulus-response coupling in the pituitary. In: Conn PM (ed) Methods in Enzymology. Academic Press, San Diego, vol 168:287-301
38. 38 Dudley DT, Pang L, Decker SJ, Bridges AJ, Saltiel AR 1995 A synthetic inhibitor of the mitogen-activated protein kinase cascade. Proc Natl Acad Sci USA 92:7686-7689
39. 39. Aless DR, Cuenda A, Cohen P, Dudley DT, Saltiel AR 1995 PD 98059 is a specific inhibitor of the activation of mitogen-activated protein kinase in vitro and in vivo. J Biol Chem 270:27489-27494
40. 40. Kolch W, Heidecker G, Lloyd P, Rapp UR 1991 Raf-1 protein kinase is required for growth of induced NIH/3T3 cells. Nature 349:426-428
41. mapk are required for fibroblast proliferation. Proc Natl Acad Sci USA 90:8319-8323
42. 42. Kaiser UB, Sabbagh E, Katzenellenbogen RA, Conn PM, Chin WW 1995 A mechanism for the differential regulation of gonadotropin subunit gene expression by gonadotropin-releasing hormone. Proc Natl Acad Sci USA 92:12280-12284
43. 43. Kaiser UB, Katzenellenbogen RA, Conn PM, Chin WW 1994 Evidence that signalling pathways by which thyrotropin-releasing hormone and gonadotropin-releasing hormone act are both common and distinct. Mol Endocrinol 8:1038-1048
44. 2+ pulsatile signals. Endocrinology 138:5227-5230
45. 45. Garrel G, McArdle CA, Hemmings BA, Counis R 1997 Gonadotropin-releasing hormone and pituitary adenylate cyclase-activating polypeptide affect levels of cyclic adenosine 3′,5′-monophosphate-dependent protein kinase A (PKA) subunits in the clonal gonadotrope alphaT3-1 cells: evidence for cross-talk between PKA and protein kinase C pathways. Endocrinology 138:2259-2266
46. 46. Chen R-H, Abate C, Blenis J 1993 Phosphorylation of the c-Fos transrepression domain by mitogen-activated protein kinase and 90-kDa ribosomal 56 kinase. Proc Natl Acad Sci USA 90:10952-10956
47. mapk in vitro. Oncogene 8:2259-2265
48. 48. Chu B, Soncin F, Price BD, Stevenson MA, Calderwood SK 1996 Sequential phosphorylation by mitogen-activated protein kinase and glycogen synthase kinase 3 represses transcriptional activation by heat shock factor-1. J Biol Chem 271:30847-30857