Change to alanine of one out of four selectivity filter glycines in KtrB causes a two orders of magnitude decrease in the affinities for both K+ and Na+ of the Na+ dependent K+ uptake system KtrAB from Vibrio alginolyticus

FEBS Letters

Volumn 450, Issue 3, 1999, Pages 217-220

  Tholema, Nancy ^a   Bakker, Evert P ^a   Suzuki, Ayako ^b   Nakamura, Tatsunosuke ^b  

^a UNIVERSITY OF OSNABRÜCK   (Germany)

^b CHIBA UNIVERSITY   (Japan)

Author keywords

HKT1; K+ symporter family; KcsA K+ channel family; Na+ K+ symporter; P loop; Selectivity filter

Indexed keywords

ALANINE; GLYCINE; POTASSIUM; POTASSIUM CHANNEL; SODIUM;

ARTICLE; ESCHERICHIA COLI; FILTER; MEMBRANE; NONHUMAN; PLASMID; POTASSIUM TRANSPORT; PRIORITY JOURNAL; VIBRIO ALGINOLYTICUS;

ALANINE; AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; BACTERIAL PROTEINS; CARRIER PROTEINS; CATION TRANSPORT PROTEINS; GLYCINE; MEMBRANE PROTEINS; MOLECULAR SEQUENCE DATA; MUTAGENESIS; POTASSIUM; SODIUM; VIBRIO;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI; VIBRIO ALGINOLYTICUS;

EID: 0032921035     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-5793(99)00504-9     Document Type: Article

References (30)

1. Doyle D.A., Cabral J.M., Pfuetzner R.A., Kuo A., Gulbis J.M., Cohen S.L., Chait B.T., MacKinnon R. Science. 280:1998;69-77.
2. Jan L.Y., Jan Y.N. Nature. 371:1994;119-122.
3. Nakamura T., Yuda R., Unemoto T., Bakker E.P. J. Bacteriol. 180:1998;3491-3494.
4. Diatloff E., Kumar R., Schachtman D.P. FEBS Lett. 432:1998;31-36.
5. Durell, S.R., Hao, Y., Nakamura, T., Bakker, E.P. and Guy, H.R. (1999) Biophys. J. (submitted).
6. Schachtman D.P., Schroeder J.I. Nature. 370:1994;655-658.
7. Gaber R.F., Styles C.A., Fink G.R. Mol. Cell. Biol. 8:1988;2848-2859.
8. Ko C.H., Gaber R.F. Mol. Cell. Biol. 11:1991;4266-4273.
9. Takase K., Kakinuma S., Yamato I., Konishi K., Igarashi K., Kakinuma Y. J. Biol. Chem. 269:1994;11037-11044.
10. Schlösser A., Kluttig S., Hamann A., Bakker E.P. J. Bacteriol. 173:1991;3170-3176.
11. Schlösser A., Meldorf M., Stumpe S., Bakker E.P., Epstein W. J. Bacteriol. 177:1995;1908-1910.
12. Durell, S.R. and Guy, H.R. (1999) Biophys. J. (submitted).
13. Murata T., Takase K., Yamato I., Igarashi K., Kakinuma Y. J. Biol. Chem. 271:1996;10042-10047.
14. Clayton R.A., White O., Ketchum K.A., Venter J.C. Nature. 387:1996;459-462.
15. Stumpe S., Bakker E.P. Arch. Microbiol. 167:1997;126-136.
16. Ho S.N., Hunt H.D., Horton R.M., Pullen J.K., Pease L.R. Gene. 77:1989;51-59.
17. Epstein W., Kim B.S. J. Bacteriol. 108:1971;639-644.
18. Bakker E.P., Mangerich W.E. J. Bacteriol. 147:1981;820-826.
19. Bakker E.P., Kroll R.G., Booth I.R. FEMS Microbiol. Lett. 23:1984;293-297.
20. Sörensen E., Rosen B.P. Biochemistry. 19:1980;1458-1462.
21. Tokuda H., Unemoto T. Biochem. Biophys. es. Commun. 102:1981;265-271.
22. Atsumi T., McCarter L., Imae Y. Nature. 355:1992;182-184.
23. Tokuda H., Sugasawa M., Unemoto T. J. Biol. Chem. 257:1982;788-794.
24. Rubio F., Gassmann W., Schroeder J.I. Science. 270:1995;1660-1663.
25. Lichtenberg-Fraté H., Reid J.D., Heyer M., Hofer M. J. Membr. Biol. 152:1996;169-181.
26. Bakker, E.P. (1993) in: Alkali Cation Transport in Prokaryotes (Bakker, E.P., Ed.), pp. 253-276, CRC Press, Boca Raton, FL.
27. Yamato, I. and Anraku, Y. (1993) in: Alkali Cation Transport in Prokaryotes (Bakker, E.P., Ed.), pp. 53-76, CRC Press, Boca Raton, FL.
28. Lü Q., Miller C. Science. 268:1995;304-307.
29. Quick M., Tebbe S., Jung H. Eur. J. Biochem. 239:1997;732-736.
30. Jung H. Biochim. Biophys. Acta. 1365:1998;60-64.