Coordinate intracellular expression of Salmonella genes induced during infection

Journal of Bacteriology

Volumn 181, Issue 3, 1999, Pages 799-807

  Heithoff, Douglas M ^a   Conner, Christopher P ^a   Hentschel, Ute ^a,c   Govantes, Fernando ^a,d   Hanna, Philip C ^b   Mahan, Michael J ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b DUKE UNIVERSITY MEDICAL CENTER   (United States)

^c UNIVERSITY OF WÜRZBURG   (Germany)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FERROUS ION; MAGNESIUM;

ANIMAL CELL; ARTICLE; BACTERIAL GENE; CONTROLLED STUDY; EPITHELIUM CELL; GENE EXPRESSION; GENE FUSION; HUMAN; HUMAN CELL; MACROPHAGE; MOUSE; NONHUMAN; PH; PRIORITY JOURNAL; REGULON; SALMONELLA TYPHIMURIUM; SALMONELLOSIS;

ANIMALIA; BACTERIA (MICROORGANISMS); MAMMALIA; MURINAE; NEGIBACTERIA; SALMONELLA; SALMONELLA TYPHIMURIUM; TYPHIMURIUM;

EID: 0032917462     PISSN: 00219193     EISSN: None     Source Type: Journal    
DOI: 10.1128/jb.181.3.799-807.1999     Document Type: Article

References (43)

1. Ailion, M., T. A. Bobik and J. R. Roth. 1993. Two global regulatory systems (Crp and Arc) control the cobalamin/propanediol regulon of Salmonella typhimurium. J. Bacteriol. 175:7200-7208.
2. Alpuche-Aranda, C. M., J. A. Swanson, W. P. Loomis, and S. I. Miller. 1992. Salmonella typhimurium activates virulence gene transcription within acidified macrophage phagosomes. Proc. Natl. Acad. Sci. USA 89:10079-10083.
3. Bearson, B., L. L. Wilson, and J. W. Foster. 1998. A low pH-inducible PhoPQ-dependent acid tolerance response protects Salmonella typhimurium against inorganic acid stress. J. Bacteriol. 180:2409-2417.
4. Blanc-Potard, A. B., and E. A. Groisman. 1997. The Salmonella selC locus contains a pathogenicity island mediating intramacrophage survival. EMBO J. 16:5376-5385.
5. 12 synthesis and propanediol degradation. J. Bacteriol. 174:2253-2266.
6. Burns-Keliher, L., C. A. Nickerson, B. J. Morrow, and R. C. Curtiss III. 1998. Cell-specific proteins synthesized by Salmonella typhimurium. Infect. Immun. 66:856-861.
7. Chan, R K., D. Botstein, T. Watanabe, and V. Ogata. 1972. Specialized transduction of tetracycline resistance by phage P22 in Salmonella typhimurium. II. Properties of a high-frequency-transducing lysate. Virology 50: 883-898.
8. Connor, C. P., D. M. Heithoff, and M. J. Mahan. 1998. In vivo gene expression: contributions to infection, virulence, and pathogenesis. Curr. Top. Microbiol. Immunol. 225:1-12.
9. Connor, C. P., D. M. Heithoff, S. M. Julio, R. L. Sinsheimer, and M. J. Mahan. 1998. Differential patterns of acquired virulence genes distinguish Salmonella strains. Proc. Natl. Acad. Sci. USA 95:4641-4645.
10. Davis, R. W., D. Botstein, and J. R. Roth. 1980. Advanced bacterial genetics. Cold Spring Harbor Laboratory Press, Plainview, N.Y.
11. Earhart, C. F. 1996. Uptake and metabolism of iron and molybdenum, p. 1075-1090. In F. C. Neidhardt, R. Curtiss III, J. L. Ingraham, E. C. C. Lin, K. B. Low, B. Magasanik, W. S. Reznikoff, M. Riley, M. Schaechter, and H. E. Umbarger (ed.), Escherichia coli and Salmonella: cellular and molecular biology, 2nd ed. ASM Press, Washington, D.C.
12. Fang, F. C., M. Krause, C. Roudier, J. Fierer, and D. G. Guiney. 1991. Growth regulation of a Salmonella plasmid gene essential for virulence. J. Bacteriol. 173:6783-6789.
13. Fierer, J., L. Eckmann, F. Fang, C. Pfeifer, B. B. Finlay, and D. Guiney. 1993. Expression of the Salmonella virulence plasmid gene spvB in cultured macrophages and nonphagocytic cells. Infect. Immun. 61:5231-5236.
14. Fleckenstein, J. M., D. J. Kopecko, R. L. Warren, and E. A. Elsinghorst. 1996. Molecular characterization of the tia invasion locus from enterotoxigenic Escherichia coli. Infect. Immun. 64:2256-2265.
15. Garcia-del Portillo, F., J. W. Foster, M. E. Maguire, and B. B. Finlay. 1992. Characterization of the micro-environment of Salmonella typhimurium-containing vacuoles within MDCK epithelial cells. Mol. Microbiol. 6:3289-3297.
16. 2+ as an extracellular signal: environmental regulation of Salmonella virulence. Cell 84:165-174.
17. Goldberg, M. B., V. J. DiRita, and S. B. Calderwood. 1990. Identification of an iron-regulated virulence determinant in Vibrio cholerae, using TnphoA mutagenesis. Infect. Immun. 58:55-60.
18. Groisman, E. A., and F. Heffron. 1995. Regulation of Salmonella virulence by two-component regulatory systems, p. 319-332. In J. A. Hoch and T. J. Silhavy (ed.), Two-component signal transduction. ASM Press, Washington, D.C.
19. Gulig, P. A., H. Danbara, D. G. Guiney, A. J. Lax, F. Norel, and M. Rhen. 1993. Molecular analysis of the spv virulence genes of the Salmonella virulence plasmids. Mol. Microbiol. 7:825-830.
20. Gunn, J. S., E. L. Hohman, and S. I. Miller. 1996. Transcriptional regulation of Salmonella virulence: a PhoQ periplasmic domain mutation results in increased net phosphotransfer to PhoP. J. Bacteriol. 178:6369-6373.
21. Gunn, J. S, and S. I. Miller. 1996. PhoP-PhoQ activates transcription of pmrAB, encoding a two-component regulatory systems involved in Salmonella typhimurium antimicrobial peptide resistance. J. Bacteriol. 178:6857-6864.
22. Hall, H. K., and J. W. Foster. 1996. The role of Fur in the acid tolerance response of Salmonella typhimurium is physiologically and genetically separable from its role in iron acquisition. J. Bacteriol. 178:5683-5691.
23. Heithoff, D. M., C. P. Conner, P. C. Hanna, S. M. Julio, U. Hentschel, and M. J. Mahan. 1997. Bacterial infection as assessed by in vivo gene expression. Proc. Natl. Acad. Sci. USA 94:934-939.
24. Heithoff, D. M., C. P. Conner, and M. J. Mahan. 1997. Dissecting the biology of a pathogen during infection. Trends Microbiol. 5:509-513.
25. Krause, M., F. Fang, and D. G. Guiney. 1992. Regulation of plasmid virulence gene expression in Salmonella dublin involves an unusual operon structure. J. Bacteriol. 174:4482-4489.
26. Mahan, M. J., J. M. Slauch, and J. J. Mekalanos. 1993. Selection of bacterial virulence genes that are specifically induced in host tissues. Science 259:686-688.
27. Mahan, M. J., J. W. Tobias, J. M. Slauch, P. C. Hanna, R. J. Collier, and J. J. Mekalanos. 1995. Antibiotic-based selection for bacterial genes that are specifically induced during infection of a host. Proc. Natl. Acad. Sci. USA 92:669-673.
28. Mahan, M. J., J. M. Slauch, and J. J. Mekalanos. 1996. Environmental regulation of virulence gene expression in Escherichia, Salmonella, and Shigella spp., p. 1075-1090. In F. C. Neidhardt, R. Curtiss III, J. L. Ingraham, E. C. C. Lin, K. B. Low, B. Magasanik, W. S. Reznikoff, M. Riley, M. Schaechter, and H. E. Umbarger (ed.), Escherichia coli and Salmonella: cellular and molecular biology. 2nd ed. ASM Press, Washington, D.C.
29. Mekalanos, J. J. 1992. Environmental signals controlling the expression of virulence determinants in bacteria. J. Bacteriol. 174:1-7.
30. Miller, J. F., J. J. Mekalanos, and S. Falkow. 1989. Coordinate regulation and sensory transduction in the control of bacterial virulence genes. Science 243:916-922.
31. Miller, S. I., and J. J. Mekalanos. 1990. Constitutive expression of the PhoP regulon attenuates Salmonella virulence and survival within macrophages. J. Bacteriol. 172:2485-2490.
32. Miller, S. I., A. M. Kukral, and J. J. Mekalanos. 1989. A two component regulatory system (phoP and phoQ) controls Salmonella typhimurium virulence. Proc. Natl. Acad. Sci. USA 86:5054-5058.
33. Neidhardt, F. C., P. L. Bloch, and D. F. Smith. 1974. Culture medium for enterobacteria. J. Bacteriol. 119:736-747.
34. 12) biosynthetic genes of Salmonella typhimurium. J. Bacteriol. 175:3303-3316.
35. Sanderson, K. E., A. Hessel, S.-L. Liu, and K. E. Rudd. 1996. The genetic map of Salmonella typhimurium, edition VIII, p. 1903-1999. In F. C. Neidhardt, R. Curtiss III, J. L. Ingraham, E. C. C. Lin, K. B. Low, B. Magasanik, W. S. Reznikoff, M. Riley, M. Schaechter, and H. E. Umbarger (ed.), Escherichia coli and Salmonella: cellular and molecular biology, 2nd ed. ASM Press, Washington, D.C.
36. Schmieger, H. 1972. Phage P22-mutants with increased or decreased transduction abilities. Mol. Gen. Genet. 119:75-88.
37. Slauch, J. M., and T. Silhavy. 1991. cis-acting ompF mutations that result in OmpR-dependent constitutive expression. J. Bacteriol. 173:4039-4048.
38. Soncini, F. C., E. Garcia Vescovi, and E. A. Groisman. 1995. Transcriptional autoregulation of the Salmonella typhimurium phoPQ operon. J. Bacteriol. 177:4364-4371.
39. Soncini, F. C., and E. A. Groisman. 1996. Two-component regulatory systems can interact to process multiple environmental signals. J. Bacteriol. 178:6796-6801.
40. Soncini, F. C., E. Garcia Vescovi, F. Solomon, and E. A. Groisman. 1996. Molecular basis of the magnesium deprivation response in Salmonella typhimurium: identification of PhoP-regulated genes. J Bacteriol. 178:5092-5099.
41. Tsolis, R. M., A. J. Baumler, I. Stojiljkovic, and F. Heffron. 1995. Fur regulon of Salmonella lyphimurium: identification of new iron-regulated genes. J. Bacteriol. 177:4628-4637.
42. Waldor, M. K., and J. J. Mekalanos. 1996. Lysogenic conversion by a filamentous phage encoding cholera toxin. Science 272:1910-1914.
43. Williams, J. M., G. Chen, L. Zhu, and R. F. Rest. 1998. Using the yeast two-hybrid system to identify human epithelial cell proteins that bind gonococcal Opa proteins: intracellular gonococci bind pyruvate kinase via their Opa proteins and require host pyruvate for growth. Mol. Microbiol. 27:171-186.