Biochemical, hemodynamic, and vascular evidence concerning the free radical hypothesis of nitrate tolerance

Journal of Cardiovascular Pharmacology

Volumn 33, Issue 5, 1999, Pages 685-690

  Milone, Stephen D ^a   Pace Asciak, Cecil R ^a,b   Reynaud, Denis ^b   Azevedo, Eduardo R ^c   Newton, Gary E ^c   Parker, John D ^c  

^a UNIVERSITY OF TORONTO   (Canada)

^b HOSPITAL FOR SICK CHILDREN RESEARCH INSTITUTE   (Canada)

^c MOUNT SINAI HOSPITAL   (Canada)

Author keywords

F2 Isoprostanes; Free radicals; Lipid peroxidation products; Nitrate tolerance; Plethysmography; Vitamin C

Indexed keywords

8 ISOPROSTAGLANDIN F2 ALPHA; ASCORBIC ACID; BIOCHEMICAL MARKER; FREE RADICAL; GLYCERYL TRINITRATE; NITRATE; SUPEROXIDE;

ADULT; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; DOUBLE BLIND PROCEDURE; DRUG TOLERANCE; HEMODYNAMIC PARAMETERS; HUMAN; HUMAN EXPERIMENT; LIPID PEROXIDATION; MALE; PLETHYSMOGRAPHY; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SUBLINGUAL DRUG ADMINISTRATION; SYSTOLIC BLOOD PRESSURE; TRANSDERMAL DRUG ADMINISTRATION; VASCULAR ENDOTHELIUM;

ADMINISTRATION, CUTANEOUS; ANTIOXIDANTS; ASCORBIC ACID; BLOOD PRESSURE; CROSS-OVER STUDIES; DOUBLE-BLIND METHOD; DRUG TOLERANCE; FOREARM; FREE RADICALS; HEMODYNAMIC PROCESSES; HUMANS; MALE; NITROGLYCERIN; OXIDATIVE STRESS; PLETHYSMOGRAPHY; VEINS;

EID: 0032916248     PISSN: 01602446     EISSN: None     Source Type: Journal    
DOI: 10.1097/00005344-199905000-00002     Document Type: Article

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