Molecular genetic alterations in radiation-induced astrocytomas

American Journal of Pathology

Volumn 154, Issue 5, 1999, Pages 1431-1438

  Brat, Daniel J ^a   James, C David ^c   Jedlicka, Anne E ^a   Connolly, Denise C ^a   Chang, Ed ^a   Castellani, Rudy J ^b   Schmid, Mathias ^d   Schiller, Martin ^a   Carson, Dennis A ^d   Burger, Peter C ^a  

^a JOHNS HOPKINS HOSPITAL   (United States)

^b UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^c MAYO CLINIC   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EPIDERMAL GROWTH FACTOR; PROTEIN P16; PROTEIN P53;

ADOLESCENT; ADULT; ARTICLE; ASTROCYTOMA; CANCER GRADING; CHROMOSOME 9P; CHROMOSOME ABERRATION; CLINICAL ARTICLE; FEMALE; GENE AMPLIFICATION; GENE SEQUENCE; GLIOBLASTOMA; GLIOMA; HUMAN; HUMAN CELL; HUMAN TISSUE; MALE; NUCLEIC ACID BASE SUBSTITUTION; ONCOGENE K RAS; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RADIATION DOSE; RADIATION INJURY; SCHOOL CHILD; SECOND CANCER; SEQUENCE ANALYSIS; TUMOR SUPPRESSOR GENE;

EID: 0032914668     PISSN: 00029440     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0002-9440(10)65397-7     Document Type: Article

References (38)

1. Harrison MJ, Wolfe DE, Lau T, Mitnick RJ, Sachdev VP: Radiation-induced meningiomas: experience at the Mount Sinai Hospital and review of the literature. J Neurosurg 1991, 75:564-574
2. Kaschten B, Flandroy P, Reznik M, Hainaut H, Stevenaert A: Radiation-induced gliosarcoma: case report and review of the literature. J Neurosurg 1995, 83:154-162
3. Simmons NE, Laws ER Jr: Glioma occurrence after sellar irradiation: case report and review. Neurosurgery 1998, 42:172-178
4. Ron E, Modan B, Boice JD Jr., Alfandary E, Stovall M, Chetrit A, Katz L: Tumors of the brain and nervous system after radiotherapy in childhood. N Engl J Med 1988, 319:1033-1039
5. Brada M, Ford D, Ashley S, Bliss JM, Crowley S, Mason M, Rajan B, Traish D: Risk of second brain tumour after conservative surgery and radiotherapy for pituitary adenoma. Br Med J 1992, 304:1343-1346
6. Rimm IJ, Li FC, Tarbell NJ, Winston KR, Sallan SE: Brain tumors after cranial irradiation for childhood acute lymphoblastic leukemia: a 13-year experience from the Dana-Farber Cancer Institute and The Children's Hospital. Cancer 1987, 59:1506-1508
7. Tada M, Sawamura Y, Abe H, Iggo R: Homozygous p53 gene mutation in a radiation-induced glioblastoma 10 years after treatment for an intracranial germ cell tumor: case report. Neurosurgery 1997, 40:393-396
8. Brüstle O, Ohgaki H, Schmitt HP, Walter GF, Ostertag H, Kleihues P: Primitive neuroectodermal tumors after prophylactic central nervous system irradiation in children: association with an activated K-ras gene. Cancer 1992, 69:2385-2392
9. Guerrero I, Villasante A, Corces V, Pellicer A: Activation of a c-K-ras oncogene by somatic mutation in mouse lymphomas induced by γ radiation. Science 1984, 225:1159-1162
10. Eckstrand AJ, James CD, Cavenee WK, Seliger B, Petterrson RF, Collins VP: Genes for epidermal growth factor receptor, transforming growth factor α, and epidermal growth factor and their expression in human gliomas in vivo. Cancer Res 1991, 51:2164-2172
11. James CD, Carlbloom E, Dumanski JP, Hansen MF, Nordenskjöld M, Collins VP, Cavenee W: Clonal genomic alterations in glioma malignancy stages. Cancer Res 1988, 48:5546-5555
12. Li J, Yen C, Liaw D, Podsypanina K, Bose S, Wang SI, Puc J, Miliaresis C, Rodgers L, McCombie R, Bigner SH, Giovanella BC, Ittmann M, Tycko B, Hibshoosh H, Wigler MH, Parsons R: PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostrate cancer. Science 1997, 275:1943-1946
13. Jen J, Harper W, Bigner SH, Bigner DD, Papadopoulos N, Markowitz S, Wilson JKV, Kinzler KW, Vogelstein B: Deletion of p16 and p15 genes in brain tumors. Cancer Res 1994, 54:6353-6358
14. Giani C, Finocchiaro G: Mutation rate of the CDKN2 gene in malignant gliomas. Cancer Res 1994, 55:6338-6339
15. Sidransky D, Mikkelsen T, Schwecheimer K, Rosenblum ML, Cavenee W, Vogelstein B: Clonal expansion of p53 mutant cells is associated with brain tumor progession. Nature 1992, 355:846-847
16. Louis DN, Gusella JF: A tiger behind many doors: multiple genetic pathways to malignant glioma. Trends Genet 1995, 11:412-415
17. Schwengel DA, Nouri N, Meyers DA, Levitt RC: Linkage mapping of the human thromboxane A2 receptor (TBXA2R) to chromosome 19p13.3 using transcribed 3′ untranslated DNA sequence polymorphisms. Genomics 1993, 18:212-215
18. Sakar FH, Kupsky WJ, Li Y-W, Sreepathi P: Analysis of p53 gene mutations in human gliomas by polymerase chain reaction-based single strand conformation polymorphisms and DNA sequencing. Diagn Mol Pathol 1994, 3:2-8
19. Koga H, Zhang S, Kumanishi T, Washiyama K, Ichikawa T, Tanaka R, Mukawa J: Analysis of p53 gene mutations in low- and high-grade astrocytomas by polymerase chain reaction-assisted single strand conformation polymorphism and immunohistochemistry. Acta Neuropathol 1994, 87:225-232
20. Oghaki H, Eibl R, Wiestler O, Yasargil M, Newcomb E, Kleihues P: p53 mutations in nonastrocytic human brain tumors. Cancer Res 1991, 51:6202-6205
21. Kovach J, McGovern R, Cassady J, Swanson S, Wold L, Vogelstein B, Somer S: Direct sequencing from touch preparations of human carcinomas: analysis of p53 mutations in breast carcinomas. J Natl Cancer Inst 1991, 83:1004-1009
22. Hunter SB, Abbott A, Varma VA, Olson JJ, Barnett DW, James CD: Reliability of differential PCR for the detection of EGFR and MDM2 gene amplification in DNA extracted from FFPE glioma tissue. J Neuropathol Exp Neurol 1995, 54:57-64
23. Perry A, Nobori T, Ru N, Anderl K, Borell TJ, Mohapatra G, Feuerstein BG, Jenkins RB, Carson DA: Detection of p16 gene deletions in gliomas: A comparison of fluorescence in situ hybridization (FISH) versus quantitative PCR. J Neuropathol Exp Neurol 1996, 56:999-1008
24. von Deimling A, von Ammon K, Schoenfeld D, Wieslter OD, Seizinger BR, Louis DN: Subsets of glioblastoma multiforme defined by molecular genetic anaylsis. Brain Pathol 1993, 3:19-26
25. Watanabe K, Tachibana O, Sato K, Yonekawa Y, Kleihues P, Ohgaki H: Overexpression of the EGF receptor and p53 mutations are mutually exclusive in the evolution of primary and secondary glioblastomas. Brain Pathol 1996, 6:217-224
26. Biernat W, Tohma Y, Yonekawa Y, Kleihues P, Ohgaki H: Alterations of cell cycle regulatory genes in primary (de novo) and secondary glioblastomas. Acta Neuropathol 1994, 94:303-309
27. Hayahi Y, Ueki K, Waha A, Wiestler OD, Louis DN, von Deimling A: Association of EGFR gene amplification and CDKN2 (p16/MTS1) gene deletion in glioblastoma multiforme. Brain Pathol 1997, 7: 871-875
28. Rasheed BK, Stenzel TT, McLendon RE, Parsons R, Friedman AH, Bigner DD, Bigner SH: PTEN gene mutations are seen in high-grade but not in low-grade gliomas. Cancer Res 1997, 57:4187-4190
29. Tohma Y, Gratas C, Biernat W, Peraud A, Fukuda M, Yonekawa Y, Kleihues P, Ohgaki H: PTEN (MMAC1) mutations are frequent in primary glioblastomas (de novo) but not in secondary glioblastomas. J Neuropathol Exp Neurol 1998, 57:684-689
30. Bos JL: Ras oncogenes in human cancer: a review. Cancer Res 1990, 49:4682-4689
31. Burger PC, Scheithauer BW, Vogel FS: Surgical Pathology of the Nervous System and its Coverings. 3rd edition. New York, Churchill Livingstone, 1991
32. Burger PC, Scheithauer BW: Tumors of the Central Nervous System. Atlas of Tumor Pathology, 3rd Series, Fascicle 10. Washington, DC, Armed Forces Institute of Pathology, 1994
33. Fontana M, Stanton C, Pompili A, Amadori S, Mandelli F, Meloni G, Riccio A, Rubinstein LJ: Late multifocal gliomas in adolescents previously treated for acute lymphoblastic leukemia. Cancer 1987, 60: 1510-1518
34. Breimer LH: Ionizing radiation-induced mutagenesis. Br J Cancer 1988, 57:6-18
35. Withers HR: Biological basis of radiation therapy for cancer. Lancet 1992, 339:156-159
36. Sankaranarayanan K, Chakraborty R: Cancer pre-disposition, radio-sensitivity and the risk of radiation-induced cancers. Part I: Background. Radiat Res 1995, 143:121-143
37. Bondy ML, Kyritsis AP, Gu J, de Andrade M, Cunningham J, Levin VA, Bruner JM, Wei Q: Mutagen sensitivity and risk of gliomas: a case-control anaylsis. Cancer Res 1996, 56:1484-1486
38. Busch D: Genetic susceptibility to radiation and chemotherapy injury: diagnosis and treatment. Int J Radiat Oncol Biol Phys 1994, 30:997-1002