An unequal crossover between the RCCX modules of the human MHC leading to the presence of a CYP21B gene and a tenascin TNXB/TNXA-RP2 recombinant between C4A and C4B genes in a patient with juvenile rheumatoid arthritis

Experimental and Clinical Immunogenetics

Volumn 16, Issue 2, 1999, Pages 81-97

  Rupert, Kristi L ^a,b   Rennebohm, Robert M ^a,b   Yu, C Yung ^a,b,c  

^a NATIONWIDE CHILDREN S HOSPITAL   (United States)

^b OHIO STATE UNIVERSITY   (United States)

^c OHIO STATE UNIVERSITY   (United States)

Author keywords

Complement C4; Juvenile rheumatoid arthritis; MHC class III region; RCCX modules; Steroid 21 hydroxylase CYP21; Tenascin TNXA and TNXB; Unequal crossover

Indexed keywords

COMPLEMENT COMPONENT C4; MAJOR HISTOCOMPATIBILITY ANTIGEN; STEROID 21 MONOOXYGENASE; TENASCIN;

ARTICLE; CONTROLLED STUDY; CROSSING OVER; DNA SEQUENCE; HAPLOTYPE; HISTOCOMPATIBILITY GENE; HUMAN; HUMAN CELL; JUVENILE RHEUMATOID ARTHRITIS; MOLECULAR CLONING; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; RECOMBINANT GENE; RESTRICTION FRAGMENT LENGTH POLYMORPHISM;

AMINO ACID SEQUENCE; ARTHRITIS, JUVENILE RHEUMATOID; BASE SEQUENCE; COMPLEMENT C4A; COMPLEMENT C4B; EYE PROTEINS; FEMALE; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MAJOR HISTOCOMPATIBILITY COMPLEX; MALE; MEMBRANE PROTEINS; MOLECULAR SEQUENCE DATA; PEDIGREE; POLYMERASE CHAIN REACTION; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH; PROTEINS; RECOMBINATION, GENETIC; STEROID 21-HYDROXYLASE; TENASCIN; TRANSLOCATION, GENETIC; TUMOR CELLS, CULTURED;

EID: 0032913040     PISSN: 02549670     EISSN: None     Source Type: Journal    
DOI: 10.1159/000019099     Document Type: Article

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