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Volumn 18, Issue 10, 1996, Pages 799-807

Aging mechanisms in fruit flies

Author keywords

[No Author keywords available]

Indexed keywords

ANIMALIA; DROSOPHILA MELANOGASTER;

EID: 0030272620     PISSN: 02659247     EISSN: None     Source Type: Journal    
DOI: 10.1002/bies.950181006     Document Type: Review
Times cited : (93)

References (70)
  • 2
    • 0024375255 scopus 로고
    • Review of genetic investigations into the aging processes of Drosophila
    • Arking, R. and Dudas, S. P. (1989). Review of genetic investigations into the aging processes of Drosophila. JAGS 37, 757-773.
    • (1989) JAGS , vol.37 , pp. 757-773
    • Arking, R.1    Dudas, S.P.2
  • 7
    • 0027469970 scopus 로고
    • Optimally, mutation and the evolution of ageing
    • Partridge, L. and Barton, N. H. (1993). Optimally, mutation and the evolution of ageing. Nature 362, 305-311.
    • (1993) Nature , vol.362 , pp. 305-311
    • Partridge, L.1    Barton, N.H.2
  • 8
    • 0029994356 scopus 로고    scopus 로고
    • Age-specific inbreeding depression and components of genetic variance in relation to the evolution of senescence
    • in press
    • Charlesworth, B. and Hughes, K. A. (1996). Age-specific inbreeding depression and components of genetic variance in relation to the evolution of senescence. Proc. Natl Acad. Sci. USA (in press).
    • (1996) Proc. Natl Acad. Sci. USA
    • Charlesworth, B.1    Hughes, K.A.2
  • 9
    • 0028147624 scopus 로고
    • A genetic analysis of senescence in Drosophila
    • Hughes, K. A. and Charlesworth, B. (1994). A genetic analysis of senescence in Drosophila. Nature 367, 64-66.
    • (1994) Nature , vol.367 , pp. 64-66
    • Hughes, K.A.1    Charlesworth, B.2
  • 10
    • 0028843224 scopus 로고
    • The evolutionary genetics of male life-history characters in Drosophila melanogaster
    • Hughes, K. A. (1995). The evolutionary genetics of male life-history characters in Drosophila melanogaster. Evolution 49, 521-537.
    • (1995) Evolution , vol.49 , pp. 521-537
    • Hughes, K.A.1
  • 11
    • 0026499119 scopus 로고
    • Demography of genotypes: Failure of the limited life-span paradigm in Drosophila melanogaster
    • Curtsinger, J. W., Fukui, H. H., Townsend, D. R. and Vaupel, J. W. (1992). Demography of genotypes: failure of the limited life-span paradigm in Drosophila melanogaster. Science 258, 461-463.
    • (1992) Science , vol.258 , pp. 461-463
    • Curtsinger, J.W.1    Fukui, H.H.2    Townsend, D.R.3    Vaupel, J.W.4
  • 12
    • 0026615207 scopus 로고
    • Slowing of mortality rates at older ages in large medfly cohorts
    • Carey, J. R., Liedo, P., Orozco, D. and Vaupel, J. W. (1992). Slowing of mortality rates at older ages in large medfly cohorts. Science 258, 457-461.
    • (1992) Science , vol.258 , pp. 457-461
    • Carey, J.R.1    Liedo, P.2    Orozco, D.3    Vaupel, J.W.4
  • 13
    • 0026327547 scopus 로고
    • How long is the human life-span?
    • Barinaga, M. (1991). How long is the human life-span? Science 254, 936-938.
    • (1991) Science , vol.254 , pp. 936-938
    • Barinaga, M.1
  • 14
    • 0000977247 scopus 로고
    • Laboratory evolution of postponed senescence in Drosophila melanogaster
    • Rose, M. R. (1984). Laboratory evolution of postponed senescence in Drosophila melanogaster. Evolution 38, 1004-1010.
    • (1984) Evolution , vol.38 , pp. 1004-1010
    • Rose, M.R.1
  • 15
    • 0000977248 scopus 로고
    • Selection for delayed senescence in Drosophila melanogaster
    • Luckinbill, L. S., Arking, R., Clare, M., Cirocco, W. and Buck, S. (1984). Selection for delayed senescence in Drosophila melanogaster. Evolution 38, 996-1003.
    • (1984) Evolution , vol.38 , pp. 996-1003
    • Luckinbill, L.S.1    Arking, R.2    Clare, M.3    Cirocco, W.4    Buck, S.5
  • 16
    • 0023627355 scopus 로고
    • Successful selection for increased longevity in Drosophila: Analysis of the survival data and presentation of a hypothesis on the genetic regulation of longevity
    • Arking, R. (1987). Successful selection for increased longevity in Drosophila: analysis of the survival data and presentation of a hypothesis on the genetic regulation of longevity. Exp. Geron. 22, 199-220.
    • (1987) Exp. Geron. , vol.22 , pp. 199-220
    • Arking, R.1
  • 17
    • 0026452745 scopus 로고
    • Direct and correlated responses to selection on age at reproduction in Drosophila melanogaster
    • Partridge, L. and Fowler, K. (1992). Direct and correlated responses to selection on age at reproduction in Drosophila melanogaster. Evolution 46, 76-91.
    • (1992) Evolution , vol.46 , pp. 76-91
    • Partridge, L.1    Fowler, K.2
  • 18
    • 0001060762 scopus 로고
    • The genetics and cytology of Drosophila subobscura. XI. Hybrid vigor and longevity
    • Clarke, J. M. and Maynard Smith, J. (1955). The genetics and cytology of Drosophila subobscura. XI. Hybrid vigor and longevity. J. Genet. 53, 172-180.
    • (1955) J. Genet. , vol.53 , pp. 172-180
    • Clarke, J.M.1    Maynard Smith, J.2
  • 19
    • 0028930267 scopus 로고
    • Genes that regulate both development and longevity in Caenorhabditis elegans
    • Larsen, P. L., Albert, P. S. and Riddle, D. L. (1995). Genes that regulate both development and longevity in Caenorhabditis elegans. Genetics 139, 1567-1583.
    • (1995) Genetics , vol.139 , pp. 1567-1583
    • Larsen, P.L.1    Albert, P.S.2    Riddle, D.L.3
  • 20
    • 0028680523 scopus 로고
    • The evolution of development in Drosophila melanogaster selected for postponed senescence
    • Chippendale, A. K., Hoang, D. T., Service, P. M. and Rose, M. R. (1994). The evolution of development in Drosophila melanogaster selected for postponed senescence. Evolution 48, 1880-1899.
    • (1994) Evolution , vol.48 , pp. 1880-1899
    • Chippendale, A.K.1    Hoang, D.T.2    Service, P.M.3    Rose, M.R.4
  • 21
    • 0027380942 scopus 로고
    • Evolutionary effects of selection on age at reproduction in larval and adult Drosophila melanogaster
    • Roper, C., Pignatelli, P. and Partridge, L. (1993). Evolutionary effects of selection on age at reproduction in larval and adult Drosophila melanogaster. Evolution 47, 445-455.
    • (1993) Evolution , vol.47 , pp. 445-455
    • Roper, C.1    Pignatelli, P.2    Partridge, L.3
  • 22
    • 0001279257 scopus 로고
    • Physiological mechanism of increased stress resistance in Drosophila melanogaster selected for postponed senescence
    • Service, P. M. (1987). Physiological mechanism of increased stress resistance in Drosophila melanogaster selected for postponed senescence. Physiol. Zool. 60, 321-326.
    • (1987) Physiol. Zool. , vol.60 , pp. 321-326
    • Service, P.M.1
  • 23
    • 0001319705 scopus 로고
    • Dessication, flight, glycogen and postponed senescence in Drosophila melanogaster
    • Graves, J. L., Toolson, E. C., Jeong, C., Vu, L. N. and Rose, M. R. (1992) Dessication, flight, glycogen and postponed senescence in Drosophila melanogaster. Physiol. Zool. 65, 268-286.
    • (1992) Physiol. Zool. , vol.65 , pp. 268-286
    • Graves, J.L.1    Toolson, E.C.2    Jeong, C.3    Vu, L.N.4    Rose, M.R.5
  • 24
    • 0026684532 scopus 로고
    • Selection on stress resistance increases longevity in Drosophila melanogaster
    • Rose, M. R., Vu, L. N., Park, S. U. and Graves, J. L. (1992) Selection on stress resistance increases longevity in Drosophila melanogaster. Exp. Geron. 27, 241-250.
    • (1992) Exp. Geron. , vol.27 , pp. 241-250
    • Rose, M.R.1    Vu, L.N.2    Park, S.U.3    Graves, J.L.4
  • 25
    • 0027767242 scopus 로고
    • The effect of superoxide dismutase alleles on aging in Drosophila
    • Tyler, R. H. et al. (1993). The effect of superoxide dismutase alleles on aging in Drosophila. Genetica 91, 141-149.
    • (1993) Genetica , vol.91 , pp. 141-149
    • Tyler, R.H.1
  • 26
    • 0029610090 scopus 로고
    • A comparative biochemical and stress analysis of genetically selected Drosophila strains with different longevities
    • Force, A. G., Staples, T., Soliman, S. and Arking, R. (1995). A comparative biochemical and stress analysis of genetically selected Drosophila strains with different longevities. Dev. Genet. 17, 340-351.
    • (1995) Dev. Genet. , vol.17 , pp. 340-351
    • Force, A.G.1    Staples, T.2    Soliman, S.3    Arking, R.4
  • 27
    • 84966195141 scopus 로고
    • Chromosomal localization and regulation of the longevity determinant genes in a selected strain of Drosophila melanogaster
    • Buck, S., Wells, R. A., Dudas, S. P., Baker, G. T. and Arking, R. (1993). Chromosomal localization and regulation of the longevity determinant genes in a selected strain of Drosophila melanogaster. Heredity 71, 11-22.
    • (1993) Heredity , vol.71 , pp. 11-22
    • Buck, S.1    Wells, R.A.2    Dudas, S.P.3    Baker, G.T.4    Arking, R.5
  • 28
    • 84966149683 scopus 로고
    • Larval regulation of adult longevity in a genetically-selected long-lived strain of Drosophila
    • Buck, S. et al. (1993). Larval regulation of adult longevity in a genetically-selected long-lived strain of Drosophila. Heredity 71, 23-32.
    • (1993) Heredity , vol.71 , pp. 23-32
    • Buck, S.1
  • 29
    • 0030297512 scopus 로고    scopus 로고
    • Factors contributing to the plasticity of the extended longevity phenotypes of Drosophila
    • in press
    • Arking, R., Force, A. G., Dudas, S. P., Buck, S. and Baker, G. T. (1996). Factors contributing to the plasticity of the extended longevity phenotypes of Drosophila. Exp. Geron. (in press).
    • (1996) Exp. Geron.
    • Arking, R.1    Force, A.G.2    Dudas, S.P.3    Buck, S.4    Baker, G.T.5
  • 30
    • 0027721217 scopus 로고
    • Genetic and environmental factors regulating the expression of an extended longevity phenotype in a long lived strain of Drosophila
    • Arking, R., Dudas, S. P. and Baker, G. T. (1993). Genetic and environmental factors regulating the expression of an extended longevity phenotype in a long lived strain of Drosophila. Genetica 91, 127-142.
    • (1993) Genetica , vol.91 , pp. 127-142
    • Arking, R.1    Dudas, S.P.2    Baker, G.T.3
  • 31
    • 0026058667 scopus 로고
    • Elevated paraquat resistance can be used as a bioassay for longevity in a genetically based long-lived strain of Drosophila
    • Arking, R., Buck, S., Berrios, A., Dwyer, S. and Baker, G. T. (1991). Elevated paraquat resistance can be used as a bioassay for longevity in a genetically based long-lived strain of Drosophila. Dev. Genet. 12, 362-370.
    • (1991) Dev. Genet. , vol.12 , pp. 362-370
    • Arking, R.1    Buck, S.2    Berrios, A.3    Dwyer, S.4    Baker, G.T.5
  • 32
    • 0028220114 scopus 로고
    • Extension of life-span by overexpression of superoxide dismutase and catalase in Drosophila melanogaster
    • Orr, W. and Sohal, R. S. (1994). Extension of life-span by overexpression of superoxide dismutase and catalase in Drosophila melanogaster. Science 263, 1128-1130.
    • (1994) Science , vol.263 , pp. 1128-1130
    • Orr, W.1    Sohal, R.S.2
  • 33
    • 0029039854 scopus 로고
    • Simultaneous overexpression of copper- and zinc-containing superoxide dismutase and catalase retards age-related oxidative damage and increases metabolic potential in Drosophila melanogaster
    • Sohal, R., Agarwal, A., Agarwal, S. and Orr, W. (1995). Simultaneous overexpression of copper- and zinc-containing superoxide dismutase and catalase retards age-related oxidative damage and increases metabolic potential in Drosophila melanogaster. J. Biol. Chem. 270, 15671-15674.
    • (1995) J. Biol. Chem. , vol.270 , pp. 15671-15674
    • Sohal, R.1    Agarwal, A.2    Agarwal, S.3    Orr, W.4
  • 34
    • 0029087068 scopus 로고
    • A coordinate upregulation of antioxidant gene activities is associated with the delayed onset of senescence in a long-lived strain of Drosophila
    • Dudas, S. P. and Arking, R. (1995). A coordinate upregulation of antioxidant gene activities is associated with the delayed onset of senescence in a long-lived strain of Drosophila. J. Geron.: Biological Sciences 50A, B117-B127.
    • (1995) J. Geron.: Biological Sciences , vol.50 A
    • Dudas, S.P.1    Arking, R.2
  • 35
    • 0024547664 scopus 로고
    • Null mutations of copper/zinc superoxide dismutase in Drosophila confers hypersensitivity to paraquat and reduced longevity
    • Phillips, J. P., Campbell, S. D., Michaud, D., Charbonneau, M. and Hilliker, A. J. (1989). Null mutations of copper/zinc superoxide dismutase in Drosophila confers hypersensitivity to paraquat and reduced longevity. Proc. Natl Acad. Sci. USA 86, 2761-2765.
    • (1989) Proc. Natl Acad. Sci. USA , vol.86 , pp. 2761-2765
    • Phillips, J.P.1    Campbell, S.D.2    Michaud, D.3    Charbonneau, M.4    Hilliker, A.J.5
  • 36
    • 0024392669 scopus 로고
    • The genetics of catalase in Drosophila melanogaster. Isolation and characterization of acatalasemic mutants
    • Mackay, W. J. and Bewley, G. C. (1989). The genetics of catalase in Drosophila melanogaster. Isolation and characterization of acatalasemic mutants. Genetics 122, 643-652.
    • (1989) Genetics , vol.122 , pp. 643-652
    • Mackay, W.J.1    Bewley, G.C.2
  • 37
    • 0026507286 scopus 로고
    • Urate-null rosy mutants of Drosophila melanogaster are hypersensitive to oxygen stress
    • Hilliker, A. J., Duyf, B., Evans, D. and Phillips, J. P. (1992). Urate-null rosy mutants of Drosophila melanogaster are hypersensitive to oxygen stress. Proc. Natl Acad. Sci. USA 89, 4343-4347.
    • (1992) Proc. Natl Acad. Sci. USA , vol.89 , pp. 4343-4347
    • Hilliker, A.J.1    Duyf, B.2    Evans, D.3    Phillips, J.P.4
  • 38
    • 0026783733 scopus 로고
    • The effects of catalase gene overexpression on life span and resistance to oxidative stress in transgenic Drosophila melanogaster
    • Orr, W. C. and Sohal, R. S. (1992). The effects of catalase gene overexpression on life span and resistance to oxidative stress in transgenic Drosophila melanogaster. Arch. Biochem. Biophys. 297, 35-41.
    • (1992) Arch. Biochem. Biophys. , vol.297 , pp. 35-41
    • Orr, W.C.1    Sohal, R.S.2
  • 39
    • 0027284743 scopus 로고
    • Molecular characterization of rescue of acatalasemic mutants of Drosophila melanogaster
    • Griswold, C. M., Matthews, A. L., Bewley, K. E. and Mahaffey, J. W. (1993). Molecular characterization of rescue of acatalasemic mutants of Drosophila melanogaster. Genetics 134, 781-788.
    • (1993) Genetics , vol.134 , pp. 781-788
    • Griswold, C.M.1    Matthews, A.L.2    Bewley, K.E.3    Mahaffey, J.W.4
  • 40
    • 0025681888 scopus 로고
    • Phenotypic consequences of copper/zinc superoxide dismutase overexpression in Drosophila melanogaster
    • Stavely, B. E., Phillips, J. P. and Hilliker, A. J. (1990). Phenotypic consequences of copper/zinc superoxide dismutase overexpression in Drosophila melanogaster. Genome 33, 867-872.
    • (1990) Genome , vol.33 , pp. 867-872
    • Stavely, B.E.1    Phillips, J.P.2    Hilliker, A.J.3
  • 41
    • 0025362247 scopus 로고
    • Overexpression of Cu-Zn superoxide dismutase in Drosophila does not affect life span
    • Seto, N. O. L., Hayashi, S. and Tener, G. M. (1990). Overexpression of Cu-Zn superoxide dismutase in Drosophila does not affect life span. Proc. Natl Acad. Sci. USA 87, 4270-4274.
    • (1990) Proc. Natl Acad. Sci. USA , vol.87 , pp. 4270-4274
    • Seto, N.O.L.1    Hayashi, S.2    Tener, G.M.3
  • 42
    • 0027293919 scopus 로고
    • Effects of Cu-Zn superoxide dismutase overexpression on life span and resistance to oxidative stress in transgenic Drosophila melanogaster
    • Orr, W. C. and Sohal, R. J. (1993). Effects of Cu-Zn superoxide dismutase overexpression on life span and resistance to oxidative stress in transgenic Drosophila melanogaster. Arch. Biochem. Biophys. 301, 34-40.
    • (1993) Arch. Biochem. Biophys. , vol.301 , pp. 34-40
    • Orr, W.C.1    Sohal, R.J.2
  • 43
    • 0025977719 scopus 로고
    • Expression of bovine superoxide dismutase in Drosophila melanogaster augments resistance to oxidative stress
    • Reveillaud, I., Niedzwiecki, A., Bensch, K. G. and Fleming, J. E. (1991). Expression of bovine superoxide dismutase in Drosophila melanogaster augments resistance to oxidative stress. Mol. Cell. Biol. 11, 632-640.
    • (1991) Mol. Cell. Biol. , vol.11 , pp. 632-640
    • Reveillaud, I.1    Niedzwiecki, A.2    Bensch, K.G.3    Fleming, J.E.4
  • 45
    • 0029022369 scopus 로고
    • Transcriptional activation by tetracyclines in mammalian cells
    • Gossen, M., Freundlieb, S., Bender, G., Muller, G., Hillen, W. and Bujard, H. (1995). Transcriptional activation by tetracyclines in mammalian cells. Science 268, 1766-1769.
    • (1995) Science , vol.268 , pp. 1766-1769
    • Gossen, M.1    Freundlieb, S.2    Bender, G.3    Muller, G.4    Hillen, W.5    Bujard, H.6
  • 47
    • 0001095194 scopus 로고
    • Protein synthesis in aging organisms
    • (ed. R. S. Sohal et al.), Raven Press: New York
    • Webster, G. C. (1985). Protein synthesis in aging organisms. In Molecular Biology of Aging: Gene Stability and Gene Expression (ed. R. S. Sohal et al.), pp. 263-289. Raven Press: New York.
    • (1985) Molecular Biology of Aging: Gene Stability and Gene Expression , pp. 263-289
    • Webster, G.C.1
  • 48
    • 0038117292 scopus 로고
    • Fruit flies with additional expression of the elongation factor EF-1α live longer
    • Shepherd, J. C. W., Walldorf, U., Hug, P. and Gehring, W. J. (1989). Fruit flies with additional expression of the elongation factor EF-1α live longer. Proc. Natl Acad. Sci. USA 86, 7520-7521.
    • (1989) Proc. Natl Acad. Sci. USA , vol.86 , pp. 7520-7521
    • Shepherd, J.C.W.1    Walldorf, U.2    Hug, P.3    Gehring, W.J.4
  • 49
    • 0028346018 scopus 로고
    • Protein synthesis elongation factor EF-1α expression and longevity in Drosophila melanogaster
    • Shikama, N., Ackerman, R. and Brack, C. (1994). Protein synthesis elongation factor EF-1α expression and longevity in Drosophila melanogaster. Proc. Natl Acad. Sci. USA 91, 4199-4203.
    • (1994) Proc. Natl Acad. Sci. USA , vol.91 , pp. 4199-4203
    • Shikama, N.1    Ackerman, R.2    Brack, C.3
  • 50
    • 0027719292 scopus 로고
    • The effects of enhanced expression of elongation factor EF-1α on lifespan in Drosophila melanogaster
    • Stearns, S. C. and Kaiser, M. (1993). The effects of enhanced expression of elongation factor EF-1α on lifespan in Drosophila melanogaster. Genetica 91, 167-182.
    • (1993) Genetica , vol.91 , pp. 167-182
    • Stearns, S.C.1    Kaiser, M.2
  • 51
    • 0024723364 scopus 로고
    • P-elament-mediated enhancer detection: A versatile method to study development in Drosophila
    • Bellen, H. J. et al. (1989). P-elament-mediated enhancer detection: a versatile method to study development in Drosophila. Genes Dev. 3, 1288-1300.
    • (1989) Genes Dev. , vol.3 , pp. 1288-1300
    • Bellen, H.J.1
  • 52
    • 0029044141 scopus 로고
    • Temporal patterns of gene expression in the antenna of the adult Drosophila melanogasler
    • Heiland, S. L. et al. (1995). Temporal patterns of gene expression in the antenna of the adult Drosophila melanogasler. Genetics 140, 549-555.
    • (1995) Genetics , vol.140 , pp. 549-555
    • Heiland, S.L.1
  • 53
    • 0028785049 scopus 로고
    • Regulation of gene expression is linked to life span in adult Drosophila
    • Rogina, B. and Helfand, S. L. (1995). Regulation of gene expression is linked to life span in adult Drosophila. Genetics 141, 1043-1048.
    • (1995) Genetics , vol.141 , pp. 1043-1048
    • Rogina, B.1    Helfand, S.L.2
  • 54
    • 0028826029 scopus 로고
    • Muscle-specific expression of Drosophila hsp70 in response to aging and oxidative stress
    • Wheeler, J. C., Bieschke, E. T. and Tower, J. (1995). Muscle-specific expression of Drosophila hsp70 in response to aging and oxidative stress. Proc. Natl Acad. Sci. USA 92, 10408-10412.
    • (1995) Proc. Natl Acad. Sci. USA , vol.92 , pp. 10408-10412
    • Wheeler, J.C.1    Bieschke, E.T.2    Tower, J.3
  • 55
    • 0025738386 scopus 로고
    • Aging affects expression of 70-kDa heat shock proteins in Drosophila
    • Niedzwiecki, A., Kongpachith, A. M. and Fleming, J. E. (1991). Aging affects expression of 70-kDa heat shock proteins in Drosophila. J. Biol. Chem. 266, 9332-9338.
    • (1991) J. Biol. Chem. , vol.266 , pp. 9332-9338
    • Niedzwiecki, A.1    Kongpachith, A.M.2    Fleming, J.E.3
  • 56
    • 0027312448 scopus 로고
    • Heat shock induces changes in the expression and binding of ubiquitin in senescent Drosophila melanogaster
    • Niedzwiecki, A. and Fleming, J. E. (1993). Heat shock induces changes in the expression and binding of ubiquitin in senescent Drosophila melanogaster. Dev. Genet. 14, 78-86.
    • (1993) Dev. Genet. , vol.14 , pp. 78-86
    • Niedzwiecki, A.1    Fleming, J.E.2
  • 57
    • 0025332602 scopus 로고
    • Changes in protein turnover after heat shock are related to accumulation of abnormal proteins in aging Drosophila melanogaster
    • Niedzwiecki, A. and Fleming, J. E. (1990) Changes in protein turnover after heat shock are related to accumulation of abnormal proteins in aging Drosophila melanogaster. Mech. Aging Dev. 52, 295-304.
    • (1990) Mech. Aging Dev. , vol.52 , pp. 295-304
    • Niedzwiecki, A.1    Fleming, J.E.2
  • 58
    • 0024022149 scopus 로고
    • Aging results in an unusual expression of Drosophila heat shock proteins
    • Fleming, J. E., Walton, J. K., Dubitsky, R. and Bensch, K. G. (1988). Aging results in an unusual expression of Drosophila heat shock proteins. Proc. Natl Acad. Sci. USA 85, 4099-4103.
    • (1988) Proc. Natl Acad. Sci. USA , vol.85 , pp. 4099-4103
    • Fleming, J.E.1    Walton, J.K.2    Dubitsky, R.3    Bensch, K.G.4
  • 59
    • 0025190717 scopus 로고
    • Decreased expression of heat shock protein 70 mRNA and protein after heat treatment in cells of aged rats
    • Fargnoli, J., Kunisada, T., Fornace, A. J., Schneider, E. L. and Holbrook, N. J. (1990). Decreased expression of heat shock protein 70 mRNA and protein after heat treatment in cells of aged rats. Proc. Natl Acad. Sci. USA 87, 846-850.
    • (1990) Proc. Natl Acad. Sci. USA , vol.87 , pp. 846-850
    • Fargnoli, J.1    Kunisada, T.2    Fornace, A.J.3    Schneider, E.L.4    Holbrook, N.J.5
  • 60
    • 0027154719 scopus 로고
    • Expression of heat shock protein 70 is altered by age and diet at the level of transcription
    • Heydari, A. R., Wu, B., Takahashi, R., Strong, R. and Richardson, A. (1993). Expression of heat shock protein 70 is altered by age and diet at the level of transcription. Mol. Cell. Biol. 13, 2909-2918.
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 2909-2918
    • Heydari, A.R.1    Wu, B.2    Takahashi, R.3    Strong, R.4    Richardson, A.5
  • 61
    • 0027244097 scopus 로고
    • Mitochondrial DNA remains intact during Drosophila aging, but the levels of mitochondrial transcripts are significantly reduced
    • Calleja, M., Pena, P., Ugalde, C., Ferreiro, C., Marco, R. and Garesse, R. (1993). Mitochondrial DNA remains intact during Drosophila aging, but the levels of mitochondrial transcripts are significantly reduced. J. Biol. Chem. 298, 18891-18897.
    • (1993) J. Biol. Chem. , vol.298 , pp. 18891-18897
    • Calleja, M.1    Pena, P.2    Ugalde, C.3    Ferreiro, C.4    Marco, R.5    Garesse, R.6
  • 62
    • 0002557105 scopus 로고
    • Accumulation of mitochondrial DNA deletions in organisms with various lifespans
    • Chen, X., Simonetti, S., Di Mauro, S. and Schon, E. A. (1993). Accumulation of mitochondrial DNA deletions in organisms with various lifespans. Bull. Mol. Biol. Med. 18, 57-66.
    • (1993) Bull. Mol. Biol. Med. , vol.18 , pp. 57-66
    • Chen, X.1    Simonetti, S.2    Di Mauro, S.3    Schon, E.A.4
  • 63
    • 0026732706 scopus 로고
    • A pattern of accumulation of a somatic deletion of mitochondrial DNA in aging human tissues
    • Cortopassi, G. A., Shibata, D., Soong, N.-W. and Amheim, N. (1992). A pattern of accumulation of a somatic deletion of mitochondrial DNA in aging human tissues. Proc. Natl Acad. Sci. USA 89, 7370-7374.
    • (1992) Proc. Natl Acad. Sci. USA , vol.89 , pp. 7370-7374
    • Cortopassi, G.A.1    Shibata, D.2    Soong, N.-W.3    Amheim, N.4
  • 64
    • 0021780444 scopus 로고
    • Age dependent changes in mitochondria
    • (ed. A. D. Woodhead, A. D. Blackett and A. Hollaender), Plenum Press, New York
    • Fleming, J. E., Miquel, J. and Bensch, K. G. (1985). Age dependent changes in mitochondria. In Molecular Biology of Aging (ed. A. D. Woodhead, A. D. Blackett and A. Hollaender), pp. 143-156. Plenum Press, New York.
    • (1985) Molecular Biology of Aging , pp. 143-156
    • Fleming, J.E.1    Miquel, J.2    Bensch, K.G.3
  • 65
    • 0028236756 scopus 로고
    • A manganese superoxide dismutase-encoding cDNA from Drosophila melanogaster
    • Duttaroy, A., Meidinger, R., Kirby, K., Carmichael, S., Hilliker, A. and Phillips, J. (1994). A manganese superoxide dismutase-encoding cDNA from Drosophila melanogaster. Gene 143, 223-225.
    • (1994) Gene , vol.143 , pp. 223-225
    • Duttaroy, A.1    Meidinger, R.2    Kirby, K.3    Carmichael, S.4    Hilliker, A.5    Phillips, J.6
  • 68
    • 0027070562 scopus 로고
    • Transposable elements as a factor in the aging of Drosophila melanogaster
    • Driver, C. J. I., and McKechnie, S. W. (1992). Transposable elements as a factor in the aging of Drosophila melanogaster. Ann. New York Acad Sci. 673, 83-91.
    • (1992) Ann. New York Acad Sci. , vol.673 , pp. 83-91
    • Driver, C.J.I.1    McKechnie, S.W.2
  • 69
    • 0029102124 scopus 로고
    • P DNA element movement in somatic cells reduces lifespan in Drosophila melanogaster. evidence in support of the somatic mutation theory of aging
    • Woodruff, R. C. and Nitikin, A. G. (1995). P DNA element movement in somatic cells reduces lifespan in Drosophila melanogaster. evidence in support of the somatic mutation theory of aging. Mut. Res. 338, 35-42.
    • (1995) Mut. Res. , vol.338 , pp. 35-42
    • Woodruff, R.C.1    Nitikin, A.G.2
  • 70
    • 0016664765 scopus 로고
    • The probability of survival of a mutant gene in an age-structured population and implications for the evolution of life-histories
    • Charlesworth, B. and Wllliamson, J. A. (1975). The probability of survival of a mutant gene in an age-structured population and implications for the evolution of life-histories. Genet. Res. 26, 1-10.
    • (1975) Genet. Res. , vol.26 , pp. 1-10
    • Charlesworth, B.1    Wllliamson, J.A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.