The vicious circle of stress and anticholinesterase responses

Neuroscientist

Volumn 5, Issue 3, 1999, Pages 173-183

  Kaufer, Daniela ^a   Friedman, Alon ^a,b   Soreq, Hermona ^a  

^a HEBREW UNIVERSITY OF JERUSALEM   (Israel)

^b BEN GURION UNIVERSITY OF THE NEGEV   (Israel)

Author keywords

Acetylcholinesterase inhibitors; Blood brain barrier; c fos; Psychological stress; Transgenic overexpression

Indexed keywords

ACETYLCHOLINE; ACETYLCHOLINESTERASE; CALCIUM; CHOLINESTERASE INHIBITOR; PROTEIN C FOS; PYRIDOSTIGMINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; BLOOD BRAIN BARRIER; BRAIN SLICE; COGNITIVE DEFECT; CONTROLLED STUDY; FEEDBACK SYSTEM; HIPPOCAMPUS; HYPOTHALAMUS HYPOPHYSIS ADRENAL SYSTEM; MENTAL STRESS; MOTOR DYSFUNCTION; MOUSE; NEUROPHYSIOLOGY; NEUROTOXICITY; NONHUMAN; REVIEW; SEIZURE SUSCEPTIBILITY; TRANSGENIC MOUSE;

EID: 0032906364     PISSN: 10738584     EISSN: None     Source Type: Journal    
DOI: 10.1177/107385849900500314     Document Type: Review

References (68)

1. Sapolsky RM. Why stress is bad for your brain. Science 1996; 273:749-50.
2. McEwen BS. Possible mechanisms for atrophy of the human hippocampus. Mol Psychiatry 1997;2:255-62.
3. Bremner JD, Randall P, Vermetten E, Staib L, Bronen RA, Mazure C, et al. Magnetic resonance imaging-based measurement of hippocampal volume in posttraumatic stress disorder related to childhood physical and sexual abuse - a preliminary report. Biol Psychiatry 1997;41:23-32.
4. Bulloch AG. Sprouting and retraction of neurites by undamaged adult molluscan neurons. Brain Res 1984;12:368-73.
5. Burgess JW, Coss RG. Effects of chronic crowding stress on mid-brain development: changes in dendritic spine density and morphology in jewel fish optic tectum. Dev Psychol 1982;15:461-70.
6. Xu L, Anwyl R, Rowan MJ. Behavioural stress facilitates the induction of long-term depression in the hippocampus. Nature 1997; 387:497-500.
7. Kim JJ, Foy MR, Thompson RF. Behavioral stress modifies hippocampal plasticity through N-methyl-D-aspartate receptor activation. Proc Natl Acad Sci U S A 1996;93:4750-3.
8. Magarinos AM, McEwen BS, Flugge G, Fuchs E. Chronic psychosocial stress causes apical dendritic atrophy of hippocampal CA3 pyramidal neurons in subordinate tree shrews. J Neurosci 1996;16:3534-40.
9. Rosenstock L, Keifer M, Daniell WE, McConnell R, Claypoole K. Chronic central nervous system effects of acute organophosphate pesticide intoxication. The Pesticide Health Effects Study Group. Lancet 1991;338:223-7.
10. Wickelgr I. The big easy serves up a feast to visiting neuroscientists: rat model for Gulf War Syndrome? Science 1998;278:1404.
11. Soreq H, Zakut H. Human cholinesterases and anticholinesterases. San Diego (CA): Academic Press; 1993.
12. Friedman A, Kaufer D, Shemer J, Hendler I, Soreq H, Tur-Kaspa I, et al. Pyridostigmine brain penetration under stress enhances neuronal excitability and induces early immediate transcriptional response. Nat Med 1996;2:1382-5.
13. Johnson EO, Kamilaris TC, Carter CS, Calogero AE, Gold PW, Chrousos GP. The biobehavioral consequences of psychogenic stress in a small, social primate (Callithrix jacchus jacchus). Biol Psychiatry 1996;40:317-37.
14. Bremner JD, Brett E. Trauma-related dissociative states and long-term psychopathology in posttraumatic stress disorder. J Trauma Stress 1997;10:37-49.
15. Anthony J. Acetylcholinesterase activity and degenerative changes in various segments of the spinal cord of hens induced by ingestion of subchronic levels of leptophos. J Environ Sci Health 1993; 28:275-90.
16. Nio J, Breton P. Effects of organophosphates on rabbit pyramidal cells firing pattern and hippocampal theta rhythm. Brain Res Bull 1994;33:241-8.
17. Veronesi B, Jones K, Pope C. The neurotoxicity of subchronic acetylcholinesterase (AChE) inhibition in rat hippocampus. Toxicol Appl Pharmacol 1990;104:440-56.
18. Armstrong DL, Osaka T, Murphy MR, Kerenyi SZ, Miller SA, Hartgraves SL. Blockade of hippocampal long-term potentiation following soman pretreatment in the rat. Brain Res Bull 1997;43: 117-20.
19. McDonald BE, Costa LG, Murphy SD. Spatial memory impairment and central muscarinic receptor loss following prolonged treatment with organophosphates. Toxicol Lett 1988;40:42-56.
20. Petrali JP, Maxwell DM, Lenz DE, Mills KR. Effect of an anticholinesterase compound on the ultrastructure and function of the rat blood-brain barrier: a review and experiment. J Submicrosc Cytol Pathol 1991;23:331-8.
21. Maxwell DM, Castro CA, De La Hoz DM, Gentry MK, Gold MB, Solana RP, et al. Protection of rhesus monkeys against soman and prevention of performance decrement by pretreatment with acetylcholinesterase. Toxicol Appl Pharmacol 1992;115:44-9.
22. Savage EP, Keefe TJ, Mounce LM, Heaton RK, Lewis JA, Burcar PJ. Chronic neurological sequelae of acute organophosphate pesticide poisoning. Arch Enviromental Health 1988;43:38-45.
23. Winker MA. Tacrine for Alzheimer's disease: Which patient, what dose? JAMA 1994;271:1023-4.
24. Glickson M, Achiron A, Ram Z. The influence of pyridostigmine administration on human neuromuscular functions - studies in healthy human subjects. Fundam Appl Toxicol 1991;16:288-8.
25. Staddon JM, Rubin LL. Cell adhesion, cell junctions and the blood-brain barrier. Curr Opin Neurobiol 1996;6:622-7.
26. Elliott PJ, Hayward NJ, Huff MR, Nagle TL, Black KL, Bartus RT. Unlocking the blood-brain-barrier: a role for RMP-7 in brain tumor therapy. Exp Neurol 1996;242:214-24.
27. Luiten PG, de Jong GI, Van der Zee EA, van Dijken H. Ultrastructural localization of cholinergic muscarinic receptors in rat brain cortical capillaries. Brain Res 1996;720:225-9.
28. Melia KR, Ryabinin AE, Schroeder R, Bloom FE, Wilson MC. Induction and habituation of immediate early gene expression in rat brain by acute and repeated restraint stress. J Neurosci 1994; 14:5929-38.
29. Ding WQ, Larsson C, Ailing C. Stimulation of muscarinic receptors induces expression of individual fos and jun genes through different transduction pathways. J Neurochem 1998;70:1722-9.
30. Curran T, Franza BR Jr. Fos and Jun: the AP-1 connection. Cell 1988;55:395-7.
31. Hahn M, Hahn SL, Stone DM, Joh TH. Cloning of the rat gene encoding choline acetyltransferase, a cholinergic neuron-specific marker. Proc Natl Acad Sci U S A 1992;89:4387-91.
32. Ben Aziz-Aloya R, Seidman S, Timberg R, Sternfeld M, Zakut H, Soreq H. Expression of a human acetylcholinesterase promoter-reporter construct in developing neuromuscular junctions of Xenopus embryos. Proc Natl Acad Sci U S A 1993;90:2471-5.
33. Erickson JD, Varoqui H, Schafer MK, Modi W, Diebler MF, Weihe E. Functional identification of a vesicular acetylcholine transporter and its expression from a "cholinergic" gene locus. J Biol Chem 1994;269:21929-32.
34. Kaufer D, Friedman A, Seidman S, Soreq H. Acute stress facilitates long-lasting changes in cholinergic gene expression. Nature 1998;393:373-6.
35. von der Kammer H, Mayhaus M, Albrecht C, Enderich J, Wegner M, Nitsch RM. Muscarinic acetylcholine receptors activate expression of the Egr gene family of transcription factors. J Biol Chem. 1998;273:14538-44
36. Sapolsky RM. Stress glucocorticoids and damage to the nervous system: the current state of confusion. Stress 1996;1:1-19.
37. McEwen BS. Protective and damaging effects of stress mediators. N Engl J Med 1998;338:171-9.
38. Parnet P, Amindari S, Wu C, Brunke-Reese D, Goujon E, Weyhenmeyer JA, et al. Expression of type I and type II interleukin-1 receptors in mouse brain. Brain Res Mol Brain Res 1994; 27:63-70.
39. Buckingham JC, Loxley HD, Taylor AD, Flower RJ. Cytokines, glucocorticoids and neuroendocrine function. Pharmacol Res 1994;130:35-42.
40. Elliott EM, Sapolsky RM. Corticosterone impairs hippocampal neuronal calcium regulation-possible mediating mechanisms. Brain Res 1993;602:84-90.
41. Imperato A, Puglisi-Allegra S, Casolini P, Angelucci L. Changes in brain dopamine and acetylcholine release during and following stress are independent of the pituitary-adrenocortical axis. Brain Res 1991;538:111-7.
42. Helmreich DL, Cullinan WE, Watson SJ. The effect of adrenalectomy on stress-induced c-fos mRNA expression in the rat brain. Brain Res 1996;706:137-44.
43. Karpel R, Ben Aziz-Aloya R, Sternfeld M, Ehrlich G, Ginzberg D, Tarroni P, et al. Expression of three alternative acetylcholinesterase messenger RNAs in human tumor cell lines of different tissue origins. Exp Cell Res 1994;210:268-77.
44. Seidman S, Sternfeld M, Ben Aziz-Aloya R, Timberg R, Kaufer-Nachum D, Soreq H. Synaptic and epidermal accumulations of human acetylcholinesterase is encoded by alternative 3́-terminal exons. Mol Cell Biol 1995;15:2993-3002.
45. Sternfeld M, Ming G, Song H, Sela K, Timberg R, Poo M, et al. Acetylcholinesterase enhances neunte growth and synapse development through alternate contributions of its hydrolytic capacity, core protein and variable C-termini. J Neurosci 1998;18:1240-9.
46. Karpel R, Sternfeld M, Ginzberg D, Guhl E, Graessmann A, Soreq H. Overexpression of alternative human acetylcholinesterase forms modulates process extensions in cultured glioma cells. J Neurochem 1996;66:114-23.
47. Soreq H, Ben-Aziz R, Prody CA, Seidman S, Gnatt A, Neville L, et al. Molecular cloning and construction of the coding region for human acetylcholinesterase reveals a G,C-rich attenuating structure. Proc Natl Acad Sci U S A 1990;87:9688-92.
48. Muller F, Dumez Y, Massoulie J. Molecular forms and solubility of acetylcholinesterase during the embryonic development of rat and human brain. Brain Res 1985;331:295-302.
49. Cisson CM, McQuarrie CH, Sketelj J, McNamee MG, Wilson BW. Molecular forms of acetylcholinesterase in chick embryonic fast muscle: developmental changes and effects of DFP treatment. Dev Neurosci 1981;4:157-64.
50. Schegg KM, Harrington LS, Neilsen S, Zweig RM, Peacock JH. Soluble and membrane-bound forms of brain acetylcholinesterase in Alzheimer's disease. Neurobiol Aging 1992;13:697-704.
51. Beeri R, Andres C, Lev-Lehman E, Timberg R, Huberman T, Shani M, et al. Transgenic expression of human acetylcholinesterase induces progressive cognitive deterioration in mice. Curr Biol 1995;5:1063-71.
52. Lennox WJ, Harris LW, Talbot BG, Anderson DR. Relationship between reversible acetylcholinesterase inhibition and efficacy against soman lethality. Life Sci 1985;37:793-8.
53. Dirnhuber P, French MC, Green DM, Leadbeater L, Stratton JA. The protection of primates against soman poisoning by pretreatment with pyridostigmine. J Pharm Pharmacol 1979;31:295-9.
54. Layer PG, Willbold E. Novel functions of cholinesterases in development, physiology and disease. Prog Histochem Cytochem 1995;29:1-94.
55. Small DH, Reed G, Whitefield B, Nurcombe V. Cholinergic regulation of neurite outgrowth from isolated chick sympathetic neurons in culture. J Neurosci 1995;15:144-51.
56. Jones SA, Holmes C, Budd TC, Greenfield SA. The effect of acetylcholinesterase on outgrowth of dopaminergic neurons in organotypic slice culture of rat mid-brain. Cell Tissue Res 1995; 279:323-30.
57. Andres C, Beeri R, Friedman A, Lev-Lehman E, Henis S, Timberg R, et al. Acetylcholinesterase-transgenic mice display embryonic modulations in spinal cord choline acetyltransferase and neurexin Iβ gene expression followed by late-onset neuromotor deterioration. Proc Natl Acad Sci U S A 1997;94:8173-8.
58. Beeri R, Le Novere N, Mervis R, Huberman T, Grauer E, Changeux JP, et al. Enhanced hemicholinium binding and attenuated dendrite branching in cognitively impaired acetylcholinesterase-transgenic mice. J Neurochem 1997;69:2441-51.
59. Ferrer I, Gullotta F. Down's syndrome and Alzheimer's disease: dendritic spine counts in the hippocampus. Acta Neuropathol Berl 1990;79:680-5.
60. Rash JE, Hudson CS, Graham WF, Mayer RF, Warnick JE, Albuquerque EX. Freeze fracture studies of human neuromuscular junctions. Membrane alterations observed in myasthenia gravis. Lab Invest 1981;44:519-30.
61. Heckers S, Geula C, Mesulam MM. Acetylcholinesterase-rich pyramidal neurons in Alzheimer's disease. Neurobiol Aging 1992; 13:455-60.
62. Loewenstein-Lichtenstein Y, Schwarz M, Glick D, Norgaard-Pedersen B, Zakut H, Soreq H. Genetic predisposition to adverse consequences of anti-cholinesterases in "atypical" BCHE carriers. Nat Med 1995;1:1082-5.
63. Lehmann D J, Johnston C, Smith AD. Synergy between the genes for butyrylcholinesterase K variant and apolipoprotein E4 in late-onset confirmed Alzheimer's disease. Hum Mol Genet 1997;6: 1933-6.
64. Hyman BT, Tanzi R. Molecular epidemiology of Alzheimer's disease. N Engl J Med 1995;333:1283-4.
65. Farlow MR, Lahiri DK, Poirier J, Davignon J, Schneider L, Hui SL. Treatment outcome of tacrine therapy depends on apolipoprotein genotype and gender of the subjects with Alzheimer's disease. Neurology 1998;50:669-77.
66. Grifman M, Lev-Lehman E, Ginzberg D, Eckstein F, Zakut H, Soreq H, et al. Potential antisense oligonucleotide therapies for neurodegenerative diseases. In: Strauss M, Barranger JA, editors. Concepts in gene therapy. Berlin: Walter de Gruyter; 1997. p. 141-67.
67. Sussman JL, Harel M, Frolow F, Oefner C, Goldman A, Toker L, et al. Atomic structure of acetylcholinesterase from Torpedo califomica: a prototypic acetylcholine-binding protein. Science 1991; 253:872-9.
68. Gould E, Tanapat P, McEwen BS. Proliferation of granule cell precursors in the dentate gyrus of adult monkeys is diminished by stress. Proc Natl Acad Sci U S A 1998;95:3168-71.