HLA DRB1, DMA, and DMB gene polymorphisms in rheumatoid arthritis

Human Immunology

Volumn 60, Issue 3, 1999, Pages 245-249

  Reviron, Denis ^a   Du Montcel, Sophie Tezenas ^b   Foutrier, Catherine ^e   Guis, Sandrine ^e   Benazet, Jean François ^e   Auquier, Pascal ^c   Busson, Marc ^d   Roux, Hubert ^e   Mercier, Pierre ^a   Roudier, Jean ^c  

^a Etablissement de transfusion sanguine Alpes Provence   (France)

^b INSERM   (France)

^c AIX MARSEILLE UNIVERSITY   (France)

^d SAINT LOUIS HOSPITAL   (France)

^e HÔPITAL DE LA CONCEPTION   (France)

Author keywords

HLA DM; HLA DRB1; Linkage disequilibrium; Rheumatoid arthritis; Susceptibility

Indexed keywords

ADULT; ALLELISM; ARTICLE; CONTROLLED STUDY; DISEASE PREDISPOSITION; DNA POLYMORPHISM; GENE FREQUENCY; GENE LINKAGE DISEQUILIBRIUM; GENETIC SUSCEPTIBILITY; HLA SYSTEM; HUMAN; MAJOR CLINICAL STUDY; PHENOTYPE; PRIORITY JOURNAL; RHEUMATOID ARTHRITIS;

ADULT; ARTHRITIS, RHEUMATOID; FRANCE; GENETIC PREDISPOSITION TO DISEASE; HISTOCOMPATIBILITY ANTIGENS CLASS II; HLA-D ANTIGENS; HLA-DR ANTIGENS; HUMANS; LINKAGE DISEQUILIBRIUM; MEDITERRANEAN REGION; MIDDLE AGED; PHENOTYPE; POLYMORPHISM, GENETIC;

EID: 0032905453     PISSN: 01988859     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0198-8859(98)00116-5     Document Type: Article

References (17)

1. Ollier W., Thomson W. Population genetics of rheumatoid arthritis. Genetic factors. Rheum Dis Clin Nor Am. 18:1992;729-740.
2. Gregersen P., Silver J., Winchester R. The shared epitope hypothesis An approach to understanding the molecular genetics of susceptibility to rheumatoid arthritis . Arthritis Rheum. 30:1987;1205-1213.
3. Weyand C.M., Congping X., Goronzy J.J. Homozygosity for the HLA-DRB1 allele selects for extraarticular manifestations in rheumatoid arthritis. J Clin Invest. 89:1992;2033-2039.
4. Wordsworth P., Pile K., Buckely J., Lanchbury J., Ollier B., Lathrop M., Bell J. HLA heterozygosity contributes to susceptibility to rheumatoid arthritis. Am J Hum Genet. 51:1992;585-591.
5. Benazet J.F., Reviron D., Mercier P., Roux H., Roudier J. HLA-DRB1 alleles associated with rheumatoid arthritis in southern France absence of extraarticular disease despite expression of the shared epitope.J . Rheumatol. 22:1995;607-610.
6. Kelly A., Monaco J., Cho S., Trowsdale J. A new human HLA class II related locus, DM. Nature. 353:1991;571-573.
7. Busch R., Mellins E. Developing and shedding inhibitions how MHC class II molecules reach maturity . Curr Opin Immunol. 8:1996;51-58.
8. Fling S., Arp B., Pilous D. HLA-DMA and DMB genes are both required for MHC class II/peptide complex formation in antigen presenting cells. Nature. 368:1994;554-558.
9. Marsh S. HLA class II region sequences. Tissue Antigens. 51:1998;467-507.
10. Yen J.H., Chen C.J., Tsai W.C., Chang J.G., Liu H.W. HLA DMA and DMB genotyping in patients with rheumatoid arthritis. J. Rheumatol. 24:1997;442-444.
11. Takeuchi F, Nabeta H, Kuwata S, Tanimoto K, Ito K. Association of DMA and DMB with RA in Japanese. Clin Exp Rheumatol 1997 Mar 15(2):189-192.
12. Pinet V., Combe B., Avinens O., Caillat-Zucman S., Sany J., Clot J., Eliaou J. Polymorphism of the HLA-DMA and DMB genes in Rheumatoid Arthritis. Arthritis Rheum. 40:1997;854-858.
13. Singal D.P., Ye M. HLA-DM polymorphisms in patients with rheumatoid arthritis J . Rheumatol. 25:(7):1998;1295-1298.
14. Arnett F., Edworthy S., Block D. The 1987 revised ARA criteria for rheumatoid arthritis. Arthritis Rheum. 30:1987;S17.
15. Charron D, Fauchet R: Twelfth International Histocompatibility Workshop reference protocol Addendum 12-1994. Edited by: Charron D, Fauchet R. HLA et Médecine, 15 rue de l'école de médecine, 75006 Paris France.
16. Haldane J.B.S. The estimation and significance of the logarithm of a ratio of frequencies. Ann Hum Genet. 20:1955;309.
17. Crow JF, Kimura M: Generation of gametic phase disequilibrium with epistasis. In An introduction to population genetics theory. Harper International Ed Harper and Row Publisher. New York, 1970.